Publications

Xiaobai XU, Negandhi J, Min W, Tsui M, Post M, Harrison R.V, Grunebaum E Early Enzyme Replacement Therapy Improves Hearing and Immune Defects in Adenosine Deaminase Deficient-Mice. Frontiers in Immunology, (2019) Feb. 2019, Volume 10, Article 416

Deonarain AR, Harrison RV, Gordon KA, Wolter NE, Looi T, Estrada M, Propst EJ. Live porcine model for surgical training in tracheostomy and open-airway surgery. Laryngoscope. (2019) Sep 30. doi: 10.1002/lary.28309.

Harrison RV (2020) “ Historical developments in CI devices”. Forward to: Cochlear Implants and other Implantable Hearing Devices 2nd ed. Plural publications, San Diego US (in press)

James AL, Dixon PR, Harrison RV. Cochlear nerve aplasia with maintained olivo-cochlear efferent function: a distinct form of auditory neuropathy spectrum disorder. Audiology Neuro-otology, (2018) DOI: 10.1159/000487584

D’Alessandro LM, Harrison RV. c-fos immunolabeling reveals changes in neural activation patterns in chinchilla auditory midbrain following chronic neonatal exposure to a moderately-intense sound environment. Neural Plasticity, (2018) Jul 5;2018:7160362. doi: 10.1155/2018/7160362

Papsin B, Gordon K, Cushing S, James A, Harrison RV. (2018) “ Unanswered questions in pediatric hearing loss” Chapter 12 in: Pediatric Sensorineural hearing Loss S. Anne, J.E.C. Lieu, M.A.Kenna eds. Plural publishing San Diego US.

Negandhi J, Bergevin D, Harrison RV. Scanning electron microscopy of the basilar papilla of the lizard (Anolis Carolensis). Canadian Acoustics, (2017) 46 (1) 7-12.

Harrison RV [2016] “Development of the Auditory System from Periphery to Cortex”. Chap. 3 in Comprehensive Handbook of Pediatric Audiology. J. S. Gravel and R. C. Seewald (eds.) pp 23-46. Plural Publishing, San Diego US

Carraro M, Park A, Harrison RV. Partial corrosion casting to assess cochlear vasculature in mouse models of presbycusis and CMV infection. Hearing Research (2016). 332 95-103. 

Carraro M, Paroutis P, Woodside M, Harrison RV. Improved Imaging of Cleared Samples with ZEISS Lightsheet Z.1: Refractive Index on Demand. Zeiss white paper Technical report. Carl Zeiss Microscopy GmbH. (2015). 

Carraro M, Harrison RV. Degeneration of stria vascularis in age-related hearing loss; a corrosion cast study in a mouse model. Acta Otolaryngol. (2016). 136(4):385-90.

Harrison RV. How can the audiogram be more useful? J Otolaryngol Head Neck Surg. (2016). 45; pp18.

D’Alessandro L. Harrison RV. Midbrain Frequency Representation following Moderately Intense Neonatal Sound Exposure in a Precocious Animal Model (chinchilla laniger). Neural Plasticity, (2016) vol. 2016, Article ID 3734646, 11 pages, 2016.

Harrison RV. Recent Studies at the Auditory Science Laboratory, University of Toronto. Canadian Hearing Report. (2016) 11 (4) 1-4.

Carraro M, Almishal A, Hillas E, Firpo M, Park A, Harrison RV. Cytomegalovirus (CMV) infection causes degeneration of cochlear vasculature and hearing loss in a mouse model. Journal of the Association for Research in Otolaryngology (JARO) (2016) Dec 19. Vol 18(2):263-273

Harrison R.V. On the biological plausibility of Wind Turbine Syndrome. Inter. J. Environmental Health Research (2015). 25(5):463-8. 

Harrison R.V., Gordon K.A., Papsin B.C., Negandhi J. and James A.L. Auditory neuropathy spectrum disorder (ANSD) and cochlear implantation. Int. J. Pediatric Otorhinolaryngology (2015) pp .

Harrison R.V.  and others  (2015) co-author of: Council of Canadian Academies (2015): Understanding the Evidence: Wind Turbine Noise. Ottawa: The Expert Panel on Wind Turbine Noise and Human Health, Council of Canadian Academies. ISBN 978-1-926522-07-4.

Grande G., Negandhi J., Harrison R.V. and Wang L.Y. Remodelling at the calyx of Held-MNTB synapse in mice developing with unilateral conductive hearing loss. J Physiol 592.7 (2014) pp 1581-1600.

Konomi U., Kanotra S., James A.L. and Harrison R.V. Age related changes to the dynamics of contralateral DPOAE suppression in human subjects. J. Otol. Head and Neck Surg. (2014). 43:15.

Kus L.H., Negandhi J., Sklar M.C., Eskander A., Estrada M., Harrison R.V., Campisi P., Forte V. and Propst E.J. Angiogenesis in costal cartilage graft laryngotracheoplasty: A corrosion cast study in piglets. The Laryngoscope. (2014) 124: 2411-2417.

D’Alessandro L. and Harrison R.V. Excitatory and inhibitory tonotopic bands in chinchilla inferior colliculus revealed by c-fos immune-labeling. Hearing Research. (2014) 316: 122-128.

Negandhi J., Harrison A.L., Allemang C. and Harrison R.V. Time course of cochlear injury discharge (excitotoxicity) determined by ABR monitoring of contralateral cochlear events. Hearing Research. (2014) 315: 34-39. 

Papsin E., Harrison A.L., Carraro M. and Harrison R.V. Contralateral ear occlusion for improving the reliability of otoacoustic emission screening tests. Inter. J. Otolaryngology. (2014) 2014: 248187.

Wolter N.E., Harrison R.V. and James A.L. Separating the contributions of olivocochlear and middle ear muscle reflexes in modulation of distortion product otoacoustic emission levels. Audiology and Neurotology. (2014) 19: 41-48.

Harrison R.V. (2014) “Neural Plasticity in Otology”. Chapter 132 in: Otolaryngology: Head and Neck Surgery, edition 6. Cummings et al. eds. Mosby/Elsevier Sciences. ISBN: 978-0-323-05283-2.

Carraro M., Negandhi J., Kuthubutheen J., Propst E.J., Kus L., Lin V.Y.W. and Harrison R.V. Attenuating cardiac pulsations within the cochlea: Structure and function of tortuous vessels feeding Stra Vascularis. ISRN Otolaryngology. (2013) 2013:941757.

Clinkard D., Amoodi H., Kandasamy T., Grewal A.S., Chen S., Qian W., Chen J.M., Harrison R.V. and Lin V.Y.W. Changes in the cochlear vasculature and vascular endothelial growth factor and its receptors in the aging C57 mouse cochlea. ISRN Otolaryngology. (2013) 2013: 430625.  

Harrison R.V., Konomi U., Kanotra S. and James A.L. Postnatal maturation of contralateral DPOAE suppression in precocious animal model (chinchilla) of the human neonate. Acta Oto-Laryngologica. (2013) 133: 383-389.

Kus L.H., Sklar M.C., Negandhi J., Estrada M., Eskander A., Harrison R.V., Campisi P., Forte V. and Propst E.J. Corrosion casting of the subglottis following endotracheal tube intubation injury: a pilot study in Yorkshire piglets. J. Otolarynology – Head and Neck Surg. (2013) 42:52.

Propst E.J., Ngan B.T., Mount R.J., Martin-Munoz D., Blaser S., Harrison R.V., Cushing S.L., Papsin B.C. Ossicular fusion and cholesteatoma in Auriculo-Condylar Syndrome: In vivo evidence of arrest of embryogenesis. The Laryngoscope. 123: 528-532.

Harrison R.V. and Negandhi J. Resting neural activity patterns in auditory brainstem and midbrain in conductive hearing loss. Acta. Oto-Laryngologica. (2012) 132(4): 409-414.

Robert V. Harrison. The prevention of noise induced hearing loss in children – Review Article. Inter. J. Pediatrics. (2012) 2012: 473541.

Wolter N.E., Harrison R.V. and James A.L. (2012). Contralateral Suppression of Otoacoustic Emissions: Working Towards a Simple Objective Frequency Specific Test for Hearing Screening, Hearing Loss, Dr. Sadaf Naz (Ed.), ISBN: 978-953-51-0366-0.

Harrison R.V. (2012) “The Anatomy and Function of the Cochlea” In Translational Perspectives in Hearing Science. Burkard and Tremblay eds. Plural publishing. (ISBN-13: 978-1597564694).

Asrar S., Kaneko K., Takao K., Negnadhi J., Matsui M., Shibasaki K., Miyakawa T., Harrison R.V., Jia Z., Salter M.W., Tominaga M. and Fukumi-Tominaga T. DIP/WISH deficiency enhances synaptic function and performance in the Barnes maze. Molecular Brain. (2011) 4:39.

Brown T.A., Harrison R.V. Neuronal responses in chinchilla auditory cortex after postnatal exposure to frequency-modulated tones. Hearing Research. (2011) 275: 8-16.

Davids T., Mount R.J., Blaser S., Campisi P. and Harrison R.V. CT study of acoustic signal pathway through the middle ear of the sperm whale (physeter macrosepalus). Canadian Acoustics. (2011) 39(4): 13-17.

Harrison R.V. [2011] “Development of the Auditory System from Periphery to Cortex”. Chap. 3 in Comprehensive Handbook of Pediatric Audiology. J. S. Gravel and R. C. Seewald (eds.) pp 23-46. Plural Publishing (IBSN 978-1-59756-245-4).

Allegro J., Papsin B.C., Harrison R.V., Campisi P. Acoustic analysis of voice in cochlear implant recipients with post-meningitic hearing loss. Cochlear Implants Inter. (2010) 11(2): 100-116.

Brown T.A. and Harrison R.V. Postnatal development of neuronal responses to frequency-modulated tones in chinchilla auditory cortex. Brain Research. (2010) 1309: 29-39.

Schramm D.R. and Harrison R.V. Performance after cochlear implantation in children with auditory neuropathy. Cochlear implants inter. (2010) 11(supp.1): 207-212.

Harrison R.V. (2010) “Neural Plasticity in Otology”. Chapter 132 in: Otolaryngology: Head and Neck Surgery, edition 5. Cummings et al. eds. Mosby/Elsevier Sciences. pp1876-1887. (IBSN 978-0-323-05283-2).

Brown T.A. and Harrison R.V. Responses of neurons in chinchilla auditory cortex to frequency-modulated tones. J Neurophysiol. (2009) 101: 2017-2029.

Chugh B.P., Lerch J.P., Yu L.X., Pienkowski M., Harrison R.V., Henkelman M.R. and Sled J.G. Measurement of cerebral blood volume in mouse brain regions using micro-computed tomography. NeuroImage. (2009) 47: 1312-1318.

Holler T., Allegro J., Chadha N.K., Hawkes M., Harrison R.V., Forte V. and Campisi P. Voice outcomes following repeated surgical resection of laryngeal papillomata in children. J. Otolaryngology – Head and neck Surg. (2009) 141: 522-526.

Davids T., Valero J., Papsin B.C., Harrison R.V. and Gordon K.A. Effects of stimulus manipulation on electrophysiological responses in pediatric cochlear implant users. Part 1: Duration effects. Hearing Research. (2008) 244: 7-14.

Davids T., Valero J., Papsin B.C., Harrison R.V. and Gordon K.A. Effects of stimulus manipulation on electrophysiological responses in pediatric cochlear implant users. Part 2: Rate effects. Hearing Research. (2008) 244: 15-24.

Harrison R.V., Sharma A., Brown T.A., Jiwani S. and James A.L. Amplitude modulation of DPOAEs by acoustic stimulation of the contralateral ear. Acta. Oto-laryngological. (2008) 128: 404-407.

Harrison R.V. Noise-induced hearing loss in children: A ‘less than silent’ environmental danger. Paediatr. Child Health. (2008) 13(5): 377- 382.

Saburi S., Hester I., Fischer E., Pontoglio M., Eremina V., Gessler M., Quaggin S.E., Harrison R.V., Mount R.J. and McNeill H. Loss of Fat4 distrupts PCP signaling and oriented cell division and leads to cystic kidney disease. Nature Genetics. (2008) 40(8): 1010- 1015.

Gordon K.A., Papsin B.C. and Harrison R.V. Auditory brainstem activity and development evoked by apical verses basal cochlear implant electrode stimulation in children. Clinical Neurophysiology. (2007) 118: 1671-1684.

Harrison R.V. (2007) “Anatomy and Physiology of the Auditory Periphery” In: Auditory Evoked Potentials. R. Burkard; JJ Eggermont eds. Chapter 7 140-158 (Lippincott, Williams and Wilkins) (IBSN -13: 978-0-7817-5756-0).

Harrison R.V. (2007) “Development, Maintenance and Plasticity of Tonotopic Projections from Cochlea to Cortex” In: Reprogramming the Cerebral Cortex. S Lomber and JJ Eggermont eds. Pp 159-180 Oxford University Press. ((IBSN 0-19-852899-X).

Gordon K.A., Papsin B.C. and Harrison R.V. An evoked potential study of the developmental time course of the auditory nerve and brainstem in children using cochlear implants. Audiology and Neurotology. (2006) 11:7-23.

Propst E.J., Papsin B.C., Stockley T.L., Harrison R.V., Gordon K.A. Auditory responses in cochlear implant users with and without GJB2 deafness. The laryngoscope. (2006) 116: 317-327.

Propst E.J., Stockley T.L., Gordon K.A., Harrison R.V. and Papsin B.C. Ethnicity and mutations in GJB2 (connexin 26) and GJB6 (connexin 30) in a multi-cultural Canadian paediatric cochlear implant program. Inter. J. pediatric otorhinolaryngology. (2006) 70: 435-444.

Propst E.J., Blaser S., Stockley T.L., Harrison R.V., Gordon K.A. and Papsin B.C. Temporal bone imaging in GJB2 deafness. The Laryngoscope. (2006) 116: 2178- 2186.

Campisi P., Low A., Papsin B.C., Mount R.J., Cohen-Kerem R. and Harrison R.V. Acoustic analysis of the voice in pediatric cochlear implant recipients: A longitudinal study. The Laryngoscope. (2005) 115: 1046- 1050.

Gordon K.A., Papsin B.C., Harrison R.V. Effects of cochlear implant use on the electrically evoked middle latency response in children. Hearing Research. (2005) 204: 78-89.

Harrison R.V., Gordon K.A. and Mount R.J. Is there a critical period for cochlear implantation in congenitally deaf children? Analyses of hearing and speech perception performance after implantation. Devel. psychobiol. (2005) 46(3):252-61.

James A.L., Harrison R.V., Pienkowski M., Dajani H.R. and Mount R.J. Dynamics of real time DPOAE contralateral suppression in chinchillas and humans. Inter. J. Audiol. (2005) 44: 118-129.

Licup-Bravo A.T.D., Mount R.J., Minnich B., Lametschwandtner A. and Harrison R.V. Microvascular characteristics of auditory cortex: A corrosion cast study. Microsc. Microanal. (2005) 11(suppl 2): 176- 177.

Mount R.J., Licup-Bravo A.T.D., Pienkowski M., Daniel S. and Harrison R.V. Changes to vascular supply of auditory cortex following chronic conductive hearing loss. Microsc. Microanal. (2005) 11(suppl 2): 1214- 1215.

Pienkowski M. and Harrison R.V. Tone frequency maps and receptive fields in the developing chinchilla auditory cortex. J. Neurophysiol. (2005) 93: 454-466.

Pienkowski M. and Harrison R.V. Tone responses in core versus belt auditory cortex in the developing chinchilla. J. comp. Neurology. (2005) 492: 101-109.

Propst E.J., Blaser S., Gordon K.A., Harrison R.V., Papsin B.C. Temporal bone findings on computed tomography imaging in branchio-oto-renal syndrome. The Laryngoscope. (2005) 115: 1855 – 1862.

Xiang J., Daniel S.J., Ishii R., Holowka S., Harrison R.V. and Chuang S. Auditory detection of motion velocity in humans: a magnetoencephalographic study. Brain Topography. (2005) 17(3): 139- 149.