Bio-Inert High Performance Liquid Chromatography with Multi-angle Static Light Scattering, Quasi-Elastic Light Scattering and Refractive Index (Bio-HPLC-MALS-QELS-RI)

Agilent Bio-Inert HPLC and Wyatt MALS-QELS-RI

 Bio-Inert HPLC

  • Agilent 1260 Infinity II Bio-Inert LC System using non-reactive materials
  • Refrigerated chromatography system
  • Coupled to Wyatt MALS-QELS-RI
  • HPLC system includes:
    • Quaternary Pump (0.001 – 10mL/min), max operating pressure 600 bar
    • Multisampler / Autosampler (vials and multi-well plates)
    • Peltier-controlled column compartment
    • UV-VIS diode array detector
    • Fluorescence diode array detector
    • Fraction collector (glass vials / test tubes and 96-well, shallow and deep-well plates)

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 SEC-MALS-QELS-RI

  • Multi-angle Static Light Scattering, Quasi-Elastic Light Scattering and Refractive Index Detection System
  • Size exclusion chromatography (SEC) using Bio-HPLC
  • Wyatt MiniDAWN TREOS (MALS and QELS)
  • Wyatt Optilab T-rEX (RI)
  • Refrigerated detection system
  • Macromolecule molecular weight determination
  • Multimeric state, shape, polydispersity

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