About the SBC Facility
We are a core facility operating within the Peter Gilgan Centre for Research and Learning at The Hospital for Sick Children. Our facility houses a large suite of instruments used in basic research focusing on structural biology, molecular biophysics and more. Applications include molecular interaction characterization, multi-mode detection systems for assay development and implementation, large-scale association and particle analysis, structural denaturation characterization as well as a full X-ray analysis section including small / wide angle X-ray scattering for hydrodynamic and shape data collection, single crystal X-ray diffraction for detailed structure determination as well as protein crystallization support equipment.
We offer facility users access to SBC Facility-exclusive support equipment to assist with experimental set-up. This includes a full range of mechanical and electronic single and 12-channel pipettemen, refrigerated centrifuges, vortexes, balances as well as a NanoDrop, pH meter, temperature controlled sonicator, stirring plate and dry bath heating / cooling blocks.
All facility users have included access to full-time technical and experimental support provided by the dedicated facility manager.
Our facility is open to all scientists from universities, academic research hospitals and private industry members. We offer all-access, yearly facility memberships as well as individual instrument day-use packages.
SBC Facility Leadership
Scientific Directors:
Julie Forman-Kay (Head and Senior Scientist, The Hospital for Sick Children Molecular Medicine Program)
Lynne Howell (Senior Scientist, The Hospital for Sick Children Molecular Medicine Program)
Scientific Advisory Board:
Jean-Philippe Julien (Senior Scientist, The Hospital for Sick Children Molecular Medicine Program)
Simon Sharpe (Senior Scientist, The Hospital for Sick Children Molecular Medicine Program)
Frank Sicheri (Senior Investigator, The Lunenfeld-Tanenbaum Research Institute)
Facility Manager:
Greg Wasney (The Hospital for Sick Children Research Institute)
Facility Research Technicians:
James Magnus Jorgensen (The Hospital for Sick Children Research Institute)
Mario Vargas (The Hospital for Sick Children Research Institute)
Anthony Semesi (The Hospital for Sick Children Research Institute)
