About the SBC Facility
We are a core facility operating within the Peter Gilgan Centre for Research and Learning at The Hospital for Sick Children. Our facility houses a large suite of instruments used in basic research focusing on structural biology, molecular biophysics and more. Applications include molecular interaction characterization, multi-mode detection systems for assay development and implementation, large-scale association and particle analysis, structural denaturation characterization as well as a full X-ray analysis section including small / wide angle X-ray scattering for hydrodynamic and shape data collection, single crystal X-ray diffraction for detailed structure determination as well as protein crystallization support equipment.
We offer facility users access to SBC Facility-exclusive support equipment to assist with experimental set-up. This includes a full range of mechanical and electronic single and 12-channel pipettemen, refrigerated centrifuges, vortexes as well as temperature controlled sonicator, stirring plate and dry bath heating / cooling blocks.
All facility users have included access to full-time technical and experimental support provided by the dedicated facility manager.
Our facility is open to all scientists from universities, academic research hospitals and private industry members. We offer all-access, yearly facility memberships as well as individual instrument day-use packages.
Please browse this website to learn more about the facility’s available instrumentation and capabilities.
SBC Facility Leadership
Julie Forman-Kay (Head and Senior Scientist, The Hospital for Sick Children Molecular Medicine Program)
Lynne Howell (Senior Scientist, The Hospital for Sick Children Molecular Medicine Program)
Scientific Advisory Board:
Jean-Philippe Julien (Senior Scientist, The Hospital for Sick Children Molecular Medicine Program)
Jason Maynes (Scientist, The Hospital for Sick Children Molecular Medicine Program)
Simon Sharpe (Senior Scientist, The Hospital for Sick Children Molecular Medicine Program)
Frank Sicheri (Senior Investigator, The Lunenfeld-Tanenbaum Research Institute)
Greg Wasney (The Hospital for Sick Children Research Institute)
Facility Research Technicians:
James Magnus Jorgensen (The Hospital for Sick Children Research Institute)