FFF-MALS
Bio-Inert High Performance Liquid Chromatography with Field-Flow Fractionation, Multi-angle Static Light Scattering, Dynamic Light Scattering and Refractive Index (Bio-HPLC-FFF-MALS-DLS-RI)
Agilent Technologies Bio-Inert HPLC and Wyatt Technology FFF-MALS-DLS-RI
Bio-Inert HPLC
- Agilent 1260 Infinity II Bio-Inert LC System using non-reactive materials
- Room temperature or component refrigerated
- Coupled to Wyatt FFF-MALS-DLS-RI
- HPLC system includes:
- Quaternary Pump (0.001 – 10 mL/min), max operating pressure 600 bar
- Multisampler / Autosampler (vials and multi-well plates)
- Bio-inert manual injector for larger injection volumes
- Peltier-controlled column compartment
- UV-VIS diode array detector
- Fluorescence diode array detector
- Fraction collector (glass vials / test tubes and 96-well, shallow and deep-well plates)
FFF-MALS-DLS-RI
- Field-Flow Fractionation, Multi-angle Static Light Scattering, Dynamic Light Scattering and Refractive Index Detection System
- Size exclusion chromatography (SEC-MALS) available
- Wyatt Technology Eclipse (FFF) with Dilution Control Module
- Wyatt Technology DAWN (18-angle MALS and DLS)
- Wyatt Technology Optilab (RI)
- Eclipse Short Channel, 350 µM and 500 µM fixed heights
- Eclipse Semi-preparative Channel, variable heights
- Refrigerated detection system
- Separation and characterization of macromolecules and nanoparticles from 1 to 1,000 nm in size
- Macromolecule molecular weight determination
- Multimeric state, shape, polydispersity