- The No-OUCH trial has now finished recruiting. It used a patient preference approach to randomization to evaluate the comparative effectiveness of ibuprofen alone, or in combination with acetaminophen or hydromorphone, in clinical pain relief for suspected fractures.
- The The DOSE-AGE Study, expected to finish recruitment Q2 2024, is a pragmatic trial that evaluates both safety and efficacy of multiple doses of ondansetron administered post-discharge to children with acute gastroenteritis
- The INK study – recruitment ongoing – evaluates the use of intranasal versus intravenous ketamine as a less painful experience in procedural sedation as it correlates with child satisfaction and healthcare team morale.
- The Bronchiolitis trial – expected to finish recruitment Q3 2024 – builds on previous evidence and will definitively confirm whether combination therapy with epinephrine and dexamethasone is effective in treating bronchiolitis and reducing infant hospitalizations.
Updated February 2024