SPARC Selected Co-authored Publications

Proteomic Characterization of a Candidate Polygenic Driver of Metabolism in Non-small Cell Lung Cancer
Journal of Molecular Biology. 2022.
Badr, H., Blutrich, R., Chan, K., Tong, J., Taylor, P., Zhang, W., Kafri, R., Röst H.L., Tsao, M., Moran, M.F.


Integrative analysis of non-small cell lung cancer patient-derived xenografts identifies distinct proteotypes associated with patient outcomes
Nature Communications. 2022.
Mirhadi, S., Tam, S., Li, Q., Moghal, N., Pham, N., Tong, J., Golbourn, B.J., Krieger, J.R., Taylor, P., Li, M., Weiss, J., Martins-Filho, S.N., Raghavan, V., Mamatjan, Y., Khan, A.A., Cabanero, M., Sakashita, S., Huo, K., Agnihotri, S., Ishizawa, K., Waddell, T.K., Zadeh, G., Yasufuku, K., Liu, G., Shepherd, F.A., Moran, M.F., Tsao, M.


Mitochondrial Aconitase ACO2 Links Iron Homeostasis with Tumorigenicity in Non-Small Cell Lung Cancer
Molecular Cancer Research. 2023.
Mirhadi, S., Zhang, Z., Pham, N., Karimzadeh, F., Pintilie, M., Tong, J., Taylor, P., Krieger, J., Pitcher, B., Sykes, J., Wybenga-Groot, L.E., Fladd, C., Xu, J., Wang, T., Cabanero, M., Li, M., Weiss, J., Sakashita, S., Zaslaver, O., Yu, M., Caudy, A.A., St-Pierre, J., Hawkins, C., Kislinger, T., Liu, G., Shepherd, F.A., Tsao, M., Moran, M.F.


Sleuthing biochemical evidence to elucidate unassigned electron density in a CBL-SLAP2 crystal complex

Structural Biology Communications. 2021.
Wybenga-Groot, L.E., McGlade, C.J.


SLAP2 Adaptor Binding Disrupts c-CBL Autoinhibition to Activate Ubiquitin Ligase Function
Journal of Molecular Biology. 2021.
Wybenga-Groot, L.E., Tench, A.J., Simpson, C.D., St. Germain, J., Raught, B., Moran, M.F., McGlade, C.J.


Numb exon 9 inclusion regulates Integrinβ5 surface expression and promotes breast cancer metastasis
Nature Communications. 2022.
Zhang, Y., Dho, S.E., Othman, K., Simpson, C.D., Lapierre, J., Bondoc, A., McGlade, J.


SPARC Acknowledged Publications

Proteome and secretome profiling of zinc availability in Cryptococcus neoformans identifies Wos2 as a subtle influencer of fungal virulence determinants
BMC Microbiology. 2021.
Ball, B., Woroszchuk, E., Sukumaran, A., West, H., Afaq, A., Carruthers-Lay, D., Muselius, B., Gee, L., Langille, M., Pladwig, S., Kazi, S., Hendriks, A., Geddes-McAlister, J.


A designer peptide against the EAG2-Kvβ2 potassium channel targets the interaction of cancer cells and neurons to treat glioblastoma
Nature Cancer. 2023.
Dong, W., Fekete, A., Chen, X., Liu, H., Beilhartz, G.L., Chen, X., Bahrampour, S., Xiong, Y., Yang, Q., Zhao, H., Kong, T., Morioka, M.S., Jung, G., Kim, J., Schramek, D., Dirks, P.B., Song, Y., Kim, T., He., Y., Wanggou, S., Li, X., Melnyk, R.A., Wang, L., Huang, X.


Differential protein abundance in the regenerating Caribbean corallimorpharian Ricordea florida
Journal of Zoo and Aquarium Research
Horricks, R., Millar, Z., Sykes, K., Lumsden, J.


Loss of mfsd8 alters the secretome during Dictyostelium aggregation
European Journal of Cell Biology. 2023.
Huber, R.J., Gray, J., Kim, W.D.


Proteomic profiling reveals engineered chitosan nanoparticles mediated cellular crosstalk and immunomodulation for therapeutic application in apical periodontitis
BioActive Materials. 2022.
Hussein, H., Kishen, A.


TRPV4 regulates β1 integrin-mediated cell-matrix adhesions and collagen remodeling
Federation of American Societies for Experimental Biology. 2023.
Ji, C., Wang, Y., Wang, Q., Wang, A., Ali, A., McCulloch, C.A.


A Proteomics Analysis of Calmodulin-Binding Proteins in Dictyostelium discoideum during the Transition from Unicellular Growth to Multicellular Development
International Journal of Molecular Sciences. 2021.
Kim, W.D., Yap, S.Q., Huber, R.B.


Coordination of metal center biogenesis in human cytochrome c oxidase
Nature Communications. 2022.
Nývltová, E., Dietz, J.V., Seravalli, J., Khalimonchuk, O., Barrientos, A.


Germination alters the microstructure, in vitro protein digestibility, α-glucosidase and dipeptidyl peptidase-IV inhibitory activities of bioaccessible fraction of pigeon pea (Cajanus cajan) seeds
Legume Sciences. 2021.
Ohanenye, I.C., Sun, X., Sarteshnizi, R.A., Udenigwe, C.C.


Vimentin tunes cell migration on collagen by controlling β1 integrin activation and clustering
Journal of Cell Science. 2021.
Ostrowska-Podhorodecka, Z., Ding, I., Lee, W., Tanic, J., Abbasi, S., Arora, P.D., Liu, R.S., Patteson, A.E., Janmey, P.A., McCulloch, C.A.


Phosphorylation of the DNA repair scaffold SLX4 drives folding of the SAP domain and activation of the MUS81-EME1 endonuclease
Cell Reports. 2022.
Payliss, B.J., Tse. Y.W., Reichheld, S.E., Lemak, A., Yun, H.Y., Houliston, S., Patel, A., Arrowsmith, C.H., Sharpe, S., Wyatt, H.D.M.


Elevated glycolysis imparts functional ability to CD8+ T cells in HIV infection
Life Science Alliance. 2021.
Rahman, A.N., Liu, J., Mujib, S., Kidane, S., Ali, A., Szep, S., Han. S., Bonner, P., Parsons, M., Benko, E., Kovacs, C., Yue, F.Y., Ostrowski, M.


Polyproline type II helical antifreeze proteins are widespread in Collembola and likely originated over 400 million years ago in the Ordovician Period
Scientific Reports. 2023.
Scholl, C.L., Holmstrup, M., Graham, L.A., Davies, P.L.


In Silico Analysis of Bioactive Peptides Produced from Underutilized Sea Cucumber By-Products—A Bioinformatics Approach
Marine Drugs. 2022.
Senadheera, T.R.L., Hossain, A., Dave, D., Shahidi, F.


Functional and physiochemical properties of protein isolates from different body parts of North Atlantic sea cucumber (Cucumaria frondosa)
Scientific Reports. 2023.
Senadheera, T.R.L., Hossain, A., Dave, D., Shahidi, F.


Chilling injury in human kidney tubule cells after subzero storage is not mitigated by antifreeze protein addition
Cryobiology. 2023.
Tomalty, H.E., Graham, L.A., Walker, V.K., Davies, P.L.


A Peptidisc-Based Survey of the Plasma Membrane Proteome of a Mammalian Cell
Molecular & Cellular Proteomics. 2023.
Zhao, Z., Khurana, A., Antony, F., Young, J.W., Hewton, K.G., Brough, Z., Zhong, Parker, S.J., Duong van Hoa, F.