• Our Paediatric Neuroinflammatory Disorders program, in collaboration with other site investigators across Canada and internationally, are currently recruiting for several studies under the following areas:
LIFESTYLE OUTCOMES

Active Teens with Multiple Sclerosis (ATOMIC) Physical Activity Study

We developed a physical activity intervention using a mobile app tailored for youth with multiple sclerosis (MS). We propose to test the feasibility of implementing this intervention in youth with multiple sclerosis (MS) and to examine the extent to which the intervention can change physical activity levels in this population. We will also evaluate improvement in regional brain volumes, mood, and quality of life in these youth. Learn more here.

You may be eligible for this study if you:

  • are between 11 and 21 years old;
  • have been diagnosed with MS or CIS.

If interested in learning more, please contact Olivia Lau (416-813-7654 x 328577).

 

Social Networks Study

The goal of this study is to understand the effects of COVID-19-related societal changes on health behaviours and mental health outcomes in children and adolescents with neuroinflammatory conditions. Learn more here.

You may be eligible for this study if you:

  • are between 8 and 18 years old;
  • have been diagnosed with a neuroinflammatory disorder.

If interested in learning more, please contact Mina Ly (416-813-7654 x 204757).

VISUAL AND NEURO-COGNITIVE OUTCOMES

Metformin in Children with MS Study

We want to see if we can repair damaged myelin in children with MS using a drug called metformin. Previous research has shown that metformin helps repair myelin in mice and may associate with decreased relapses in adults with MS and metabolic syndromes. Learn more here.

You may be eligible for this study if you:

  • are between 10 and 26 years old;
  • have been diagnosed with MS.

If interested in learning more, please contact Olivia Lau (416-813-7654 x 328576).

 

OMAS Study

The goal of this study is to investigate eye movement outcomes in relation to brain volume, cognitive function, and disease severity in pediatric OMAS. Learn more here.

You may be eligible for this study if you:

  • are between 6 and 18 years old;
  • have been diagnosed with OMAS.

If interested in learning more, please contact Shamashtika Thilagaratnam (416-813-7654 x 328576).

THERAPIES & OUTCOMES IN AUTOIMMUNE ENCEPHALOPATHY

Autoimmune Encephalitis (AE) Gene Expression Study

The goal of this study is to identify key molecular and cellular mechanisms of immune responses in childhood autoimmune encephalitides in order to help identify potential disease biomarkers and develop new targeted therapies. Learn more here.

You may be eligible for this study if you:

  • are under 18 years old;
  • have been diagnosed with autoimmune encephalitis.

If interested in learning more, please contact Carmen Yea (416-813-7654 x 308828) or Olivia Lau (416-813-7654 x 328577).

OTHER STUDIES

Neuroinflammatory Patient Registry Study

The purpose of the Registry is to collect information on children with neuroinflammatory disorders for use in research aimed to increase our knowledge of childhood neuroinflammation and to help doctors develop better ways to diagnose and treat children with this rare condition. Learn more here.

You may be eligible for this study if you:

  • are under 18 years old;
  • have been diagnosed with a neuroinflammatory disorder or a suspected neuroinflammatory disorder.

 

Acute Flaccid Paralysis (AFP) in Canadian Children Study

This study is a national collaborative retrospective evaluation of clinical and MRI outcomes of children presenting with non-polio acute onset flaccid paresis (AFP). Learn more here.

You may be eligible for this study if you:

  • are under 18 years old;
  • have been diagnosed with AFP in the past 30 days.

If interested in learning more, please contact Carmen Yea (416-813-7654 x 308828).

LIFESTYLE OUTCOMES

Check back later for new opportunities!

VISUAL AND NEURO-COGNITIVE OUTCOMES

OMAS Study

The goal of this study is to investigate eye movement outcomes in relation to brain volume, cognitive function, and disease severity in pediatric OMAS. Learn more here.

You may be eligible for this study as a healthy control participant if you:

  • are between 6 and 18 years old;
  • have no significant medical history.

If interested in learning more, please contact Shamashtika Thilagaratnam (416-813-7654 x 328576).

THERAPIES & OUTCOMES IN AUTOIMMUNE ENCEPHALOPATHY

Autoimmune Encephalitis (AE) Gene Expression Study

The goal of this study is to identify key molecular and cellular mechanisms of immune responses in childhood autoimmune encephalitides in order to help identify potential disease biomarkers and develop new targeted therapies. Learn more here.

You may be eligible for this study as a healthy control participant if you:

  • are under 18 years old;
  • have no significant medical history.

If interested in learning more, please contact Carmen Yea (416-813-7654 x 308828) or Olivia Lau (416-813-7654 x 328577).

OTHER STUDIES

Check back later for new opportunities!

Patient Opportunities
LIFESTYLE OUTCOMES

Active Teens with Multiple Sclerosis (ATOMIC) Physical Activity Study

We developed a physical activity intervention using a mobile app tailored for youth with multiple sclerosis (MS). We propose to test the feasibility of implementing this intervention in youth with multiple sclerosis (MS) and to examine the extent to which the intervention can change physical activity levels in this population. We will also evaluate improvement in regional brain volumes, mood, and quality of life in these youth. Learn more here.

You may be eligible for this study if you:

  • are between 11 and 21 years old;
  • have been diagnosed with MS or CIS.

If interested in learning more, please contact Olivia Lau (416-813-7654 x 328577).

 

Social Networks Study

The goal of this study is to understand the effects of COVID-19-related societal changes on health behaviours and mental health outcomes in children and adolescents with neuroinflammatory conditions. Learn more here.

You may be eligible for this study if you:

  • are between 8 and 18 years old;
  • have been diagnosed with a neuroinflammatory disorder.

If interested in learning more, please contact Mina Ly (416-813-7654 x 204757).

VISUAL AND NEURO-COGNITIVE OUTCOMES

Metformin in Children with MS Study

We want to see if we can repair damaged myelin in children with MS using a drug called metformin. Previous research has shown that metformin helps repair myelin in mice and may associate with decreased relapses in adults with MS and metabolic syndromes. Learn more here.

You may be eligible for this study if you:

  • are between 10 and 26 years old;
  • have been diagnosed with MS.

If interested in learning more, please contact Olivia Lau (416-813-7654 x 328576).

 

OMAS Study

The goal of this study is to investigate eye movement outcomes in relation to brain volume, cognitive function, and disease severity in pediatric OMAS. Learn more here.

You may be eligible for this study if you:

  • are between 6 and 18 years old;
  • have been diagnosed with OMAS.

If interested in learning more, please contact Shamashtika Thilagaratnam (416-813-7654 x 328576).

THERAPIES & OUTCOMES IN AUTOIMMUNE ENCEPHALOPATHY

Autoimmune Encephalitis (AE) Gene Expression Study

The goal of this study is to identify key molecular and cellular mechanisms of immune responses in childhood autoimmune encephalitides in order to help identify potential disease biomarkers and develop new targeted therapies. Learn more here.

You may be eligible for this study if you:

  • are under 18 years old;
  • have been diagnosed with autoimmune encephalitis.

If interested in learning more, please contact Carmen Yea (416-813-7654 x 308828) or Olivia Lau (416-813-7654 x 328577).

OTHER STUDIES

Neuroinflammatory Patient Registry Study

The purpose of the Registry is to collect information on children with neuroinflammatory disorders for use in research aimed to increase our knowledge of childhood neuroinflammation and to help doctors develop better ways to diagnose and treat children with this rare condition. Learn more here.

You may be eligible for this study if you:

  • are under 18 years old;
  • have been diagnosed with a neuroinflammatory disorder or a suspected neuroinflammatory disorder.

 

Acute Flaccid Paralysis (AFP) in Canadian Children Study

This study is a national collaborative retrospective evaluation of clinical and MRI outcomes of children presenting with non-polio acute onset flaccid paresis (AFP). Learn more here.

You may be eligible for this study if you:

  • are under 18 years old;
  • have been diagnosed with AFP in the past 30 days.

If interested in learning more, please contact Carmen Yea (416-813-7654 x 308828).

Healthy Control Opportunities
LIFESTYLE OUTCOMES

Check back later for new opportunities!

VISUAL AND NEURO-COGNITIVE OUTCOMES

OMAS Study

The goal of this study is to investigate eye movement outcomes in relation to brain volume, cognitive function, and disease severity in pediatric OMAS. Learn more here.

You may be eligible for this study as a healthy control participant if you:

  • are between 6 and 18 years old;
  • have no significant medical history.

If interested in learning more, please contact Shamashtika Thilagaratnam (416-813-7654 x 328576).

THERAPIES & OUTCOMES IN AUTOIMMUNE ENCEPHALOPATHY

Autoimmune Encephalitis (AE) Gene Expression Study

The goal of this study is to identify key molecular and cellular mechanisms of immune responses in childhood autoimmune encephalitides in order to help identify potential disease biomarkers and develop new targeted therapies. Learn more here.

You may be eligible for this study as a healthy control participant if you:

  • are under 18 years old;
  • have no significant medical history.

If interested in learning more, please contact Carmen Yea (416-813-7654 x 308828) or Olivia Lau (416-813-7654 x 328577).

OTHER STUDIES

Check back later for new opportunities!

LEARN MORE ABOUT OUR RESEARCH

To learn more about what our research participants do,
visit the Research Components page.

 

To view our past publications, please click here.