3D chromosome illustration with small clocks throughout

Welcome to the Yuen Lab!

We are interested in understanding how genetic and epigenetic variations contribute to human health, with a focus on neurodevelopmental and neurological disorders. Utilizing (epi)genomic technologies, we aim to develop novel disease gene discovery strategies, effective diagnostic approaches, and better treatments for the disorders. Our current research includes: gene identification, tool development, variant characterization, tandem repeats, and genetic modifiers. You can find us in the Peter Giligan Centre for Research and Learning (PGCRL) – the research arm of The Hospital for Sick Children.