Selected publications
Early human fetal lung atlas reveals the temporal dynamics of epithelial cell plasticity. Quach HT*, Farrell S*, Kanagarajah KR, Wu M, Xu X, Kallurkar P, Turinsky A, Bear C, Ratjen F, Goyal S, Mores TJ, Wong AP. (2023). bioRxiv 2023.10.27.564403 *Equal contribution
- Stage-Specific Generation of Human Pluripotent Stem Cell Derived Lung Models to Measure CFTR Function. Ngan SY, Quach HT, Laselva O, Huang EN, Mangos M, Xia S, Bear CE, Wong AP (2022). Current Protocols, 2(1), e341
- A developmental role of CFTR in cystic fibrosis lung disease pathogenesis. Huang EN*, Quach HT*, Lee J, Dierolf JG, Moraes TJ, Wong AP. Frontiers in Cell and Developmental Biology. (2021). Oct 11;9:742891.*Equal contribution
- Gene therapy for cystic fibrosis: New tools for precision medicine. Lee J, Cho A*, Huang EN*, Xu Y, Quach HT, Hu J, Wong AP. Journal of Translational Medicine. (2021). Oct 30;19(1):452.
- Modelling lung cell development using human pluripotent stem cells. Ngan SY*, Quach HT*, Dierolf JG, Laselva O, Lee J, Huang EN, Mangos M, Xia S, Wong AP. (2021). bioRxiv 2021.07.16.452691 *Equal contribution
- A new platform for high-throughput therapy testing on iPSC-derived, lung progenitor cells from Cystic Fibrosis Patients. Stem Cell Reports. Jiang JX, Wellhauser L, Laselva O, Utkina I, Bozoky Z, Gunawardena T, Ngan SY, Xia S, Eckford P, Ratjen F, Moraes TJ, Parkinson J, Wong AP and Bear CE. (2021). Stem Cell Reports. 2021 Oct 12.
- Conversion of human and mouse fibroblasts into lung-like epithelial cells. Wong AP, Shojaie S, Liang Q, Xia S, Di Paola M, Ahmadi S, Bilodeau C, Garner J, Post M, Duchesneau P, Waddell TK, Bear CE, Nagy A, Rossant J. Sci Rep. 2019 Jun 21;9(1):9027.
- The CF Canada-SickKids Program in Individual CF Therapy: A Resource for the Advancement of Personalized Medicine in CF. Eckford PW, McCormack J, Munsie L, He G, Stanojevic S, Pereira S, Ho K, Avolio J, Bartlett C, Yang JY, Wong AP, Wellhauser L, Huan LJ, Jiang J, Ouyang H, Du K, Klingel M, Kyriakopoulou L, Gonska T, Moraes TJ, Strug LJ, Rossant J, Ratjen F, Bear CE. Journal of Cystic Fibrosis 2018 Apr 20 S1569-1993(18)30086-9.
- Phenotypic profiling of CFTR modulators in patient-derived respiratory epithelia. Ahmadi S, Bozoky Z, Di Paola M, Xia S, Li C, Wong AP, Wellhauser L, Molinski S, Ip W, Ouyang H, Avolio J, Forman-Kay JD, Ratjen F, Hirota JA, Rommens J, Rossant J, Gonska T, Moraes TJ, Bear CE. NPJ Genom Med. 2017 Apr 14;2:12.
- Efficient generation of functional CFTR-expressing airway epithelial cells from human pluripotent stem cells. Wong AP, Stephanie Chin, Sunny Xia, Jodi Garner, Christine Bear, Janet Rossant. Nature Protocols. 2015 Mar;10(3):363-81.
- Directed differentiation of human pluripotent stem cells into functional airway epithelial cells expressing CFTR protein. Wong AP, Bear C, Chin S, Pasceri P, Thompson T, Huan LJ, Ratjen F, Ellis J, Rossant J. Nature Biotechnology, 2012 Sep;30(9):876-82.