Transforming growth factor beta signaling functions during mammalian kidney development. Dumbrava MG, Lacanlale JL, Rowan CJ, Rosenblum ND. Pediatric Nephrology. 2020 Sep 3. Review.

Suppressor of fused controls cerebellum granule cell proliferation by suppressing Fgf8 and spatially regulating Gli proteins. Jiwani T, Kim JJ, Rosenblum ND. Development. 2020 Feb 3;147(3):dev170274.

 

Precision Health Resource of Control iPSC Lines for Versatile Multilineage Differentiation. Hildebrandt MR, Reuter MS, Wei W, Tayebi N, Liu J, Sharmin S, Mulder J, Lesperance LS, Brauer PM, Mok RSF, Kinnear C, Piekna A, Romm A, Howe J, Pasceri P, Meng G, Rozycki M, Rodrigues DC, Martinez EC, Szego MJ, Zúñiga-Pflücker JC, Anderson MK, Prescott SA, Rosenblum ND, Kamath BM, Mital S, Scherer SW, Ellis J. Stem Cell Reports. 2019 Dec 10;13(6):1126-1141.

Generation of infant- and pediatric-derived urinary induced pluripotent stem cells competent to form kidney organoids. Mulder J, Sharmin S, Chow T, Rodrigues DC, Hildebrandt MR, D’Cruz R, Rogers I, Ellis J, Rosenblum ND. Pediatric Research. 2019 Oct 19.

Building a Professional Identity and an Academic Career Track in Translational Medicine. van Dijk SJ, Domenighetti AA, Gomez-Ospina N, Hunter P, Lindemans CA, Melotte V, van Rossum AMC, Rosenblum ND. Frontiers in Medicine. 2019 Jul 3;6:151.

Critical Gaps in Understanding the Clinician-Scientist Workforce: Results of an International Expert Meeting. Weggemans MM, Friesen F, Kluijtmans M, Prakken B, Ten Cate O, Woods NN, Rosenblum ND; International Expert Group on the Clinician-Scientist Workforce. Academic Medicine. 2019 May 21.

The Integration of Clinical and Research Training: How and Why MD-PhD Programs Work. Ng E, Jones AA, Sivapragasam M, Nath S, Mak LE, Rosenblum ND. Academic Medicine. 2019 May;94(5):664-670.

Impaired SIRT1 activity leads to diminution in glomerular endowment without accelerating age-associated GFR decline. Bellin AR, Zhang Y, Thai K, Rosenblum ND, Cullen-McEwen LA, Bertram JF, Gilbert RE. Physiological Reports. 2019 May;7(9):e14044.

Lineage-specific roles of hedgehog-GLI signaling during mammalian kidney development. D’Cruz R, Stronks K, Rowan CJ, Rosenblum ND. Pediatric Nephrology. 2019 Mar 28. Review.

Preventing Translational Scientists From Extinction: The Long-Term Impact of a Personalized Training Program in Translational Medicine on the Careers of Translational Scientists. Weggemans MM, van der Schaaf M, Kluijtmans M, Hafler JP, Rosenblum ND, Prakken BJ. Frontiers in Medicine. (Lausanne). 2018 Nov 9;5:298.

Hedgehog-GLI signaling in Foxd1-positive stromal cells promotes murine nephrogenesis via TGFβ signaling. Rowan CJ, Li W, Martirosyan H, Erwood S, Hu D, Kim YK, Sheybani-Deloui S, Mulder J, Blake J, Chen L, Rosenblum ND. Development. 2018 Jul 9;145(13).

Predictors of sustained research involvement among MD/PhD programme graduates. Skinnider MA, Twa DDW, Squair JW, Rosenblum ND, Lukac CD; Canadian MD/PhD Program Investigation Group. Medical Education. 2018 May;52(5):536-545.

Protein Kinase 2β Is Expressed in Neural Crest-Derived Urinary Pacemaker Cells and Required for Pyeloureteric Contraction. Iskander SM, Feeney MM, Yee K, Rosenblum ND. Journal of American Society of Nephrology 2018 Apr;29(4):1198-1209.

Activated Hedgehog-GLI Signaling Causes Congenital Ureteropelvic Junction Obstruction. Sheybani-Deloui S, Chi L, Staite MV, Cain JE, Nieman BJ, Henkelman RM, Wainwright BJ, Potter SS, Bagli DJ, Lorenzo AJ, Rosenblum ND. Journal of American Society of Nephrology. 2018 Feb;29(2):532-544.

The Rising Challenge of Training Physician-Scientists: Recommendations From a Canadian National Consensus Conference. Strong MJ, Busing N, Goosney DL, Harris KA, Horsley T, Kuzyk A, Lingard L, Norman WV, Rosenblum ND, Saryeddine T, Wang X. Academic Medicine. 2018 Feb;93(2):172-178.

Canadians Seeking Solutions and Innovations to Overcome Chronic Kidney Disease (Can-SOLVE CKD): Form and Function. Levin A, Adams E, Barrett BJ, Beanlands H, Burns KD, Chiu HH, Chong K, Dart A, Ferera J, Fernandez N, Fowler E, Garg AX, Gilbert R, Harris H, Harvey R, Hemmelgarn B, James M, Johnson J, Kappel J, Komenda P, McCormick M, McIntyre C, Mahmud F, Pei Y, Pollock G, Reich H, Rosenblum ND, Scholey J, Sochett E, Tang M, Tangri N, Tonelli M, Turner C, Walsh M, Woods C, Manns B. Canadian Journal of Kidney Health Disease. 2018 Jan 17;5:2054358117749530.

Suppressor of fused controls cerebellar neuronal differentiation in a manner modulated by GLI3 repressor and Fgf15. Kim JJ, Jiwani T, Erwood S, Loree J, Rosenblum ND. Developmental Dynamics. 2018 Jan;247(1):156-169.

Characteristics and outcomes of Canadian MD/PhD program graduates: a cross-sectional survey. Skinnider MA, Squair JW, Twa DDW, Ji JX, Kuzyk A, Wang X, Steadman PE, Zaslavsky K, Dey AK, Eisenberg MJ, Gagné ÈR, HayGlass KT, Lewis JF, Margetts PJ, Underhill DA, Rosenblum ND, Raymond LA. CMAJ Open. 2017 Apr 25;5(2):E308-E314.

Origin and Function of the Renal Stroma in Health and Disease. Rowan CJ, Sheybani-Deloui S, Rosenblum ND. Results & Problems in Cell Differentiation. 2017;60:205-229.

Developing translational medicine professionals: the Marie Skłodowska-Curie action model. Petrelli A, Prakken BJ, Rosenblum ND; EUtrain Fellows. Journal of Translational Medicine. 2016 Nov 29;14(1):329.

The path ahead for MD/PhD programs in Canada Commentary on Jones et al. Rosenblum ND. Clinical and Investigative Medicine. 2016 Sep 11;39(4):E140-1.

Research projects in the Surgeon-Scientist and Clinician-Investigator programs at the University of Toronto (1987-2016): a cohort study. Goldenberg NM, Steinberg BE, Rutka JT, Chen R, Cabral V, Rosenblum ND, Kapus A, Lee WL. CMAJ Open. 2016 Aug 22;4(3):E444-E447.

Professional Identity Formation and the Clinician Scientist: A Paradigm for a Clinical Career Combining Two Distinct Disciplines. Rosenblum ND, Kluijtmans M, Ten Cate O. Academic Medicine. 2016 May 31. Epub ahead of print.

Integrin-Linked-Kinase Controls Renal Branching Morphogenesis via Dual Specificity Phosphatase 8.  Smeeton J, Dhir P, Hu D, Feeney MM, Chen L, Rosenblum ND. Journal of the American Society of Nephrology. 2016 May;27(5):1465-77.

Uropathogenic E.coli (UPEC) infection induces proliferation through Enhancer of Zeste Homologue 2 (EZH2). Ting K, Aitken KJ, Penna F, Samiei AN, Sidler M, Jiang J-X, Ibrahim F, Tolg C, Delgado-Olguin P, Rosenblum ND, Bagli DJ. PLoS One. 2016 Mar 10;11(3):e0149118.

Urogenital Development in Pallister-Hall Syndrome is Disrupted in a Cell Lineage-Specific Manner by Constitutive Expression of GLI3 Repressor.  Blake J, Hu D, Rosenblum ND.  Human Molecular Genetics. 2016 Feb 1;25(3):437-47.

A New Grading System for the Management of Antenatal Hydronephrosis in Children. Dos Santos J, Parekh RS, Hassouna T, Figueroa V, Zhang Y, Salei A, Gonima P, Vargas I, Piscione TD, Farhat W, Rosenblum ND. Clinical Journal of the American Society of Nephrology. 2015 Oct 7;10(10):1783-90.

Blueprint for Action: Visioning Summit on the Future of the Workforce in Pediatrics. Sectish TC, Hay WW, Mahan JD, Mendoza FS, Spector ND, Stanton B, Szilagyi PG, Turner TL, Walker LR, and Slaw K.  Members of the Federation of Pediatric Organizations’ Visioning Summit Working Groups and Planning Committee. Pediatrics. 2015 Jul;136(1):161-9.

Insights into the renal pathogenesis in Schimke-immuno-osseous dysplasia: A renal histological characterization and expression analysis. Sarin S, Javidan A, Alexopoulou I, Svajger B, Boivin F, Chu S, Baradaran-Heravi A, Boerkoel CF, Rosenblum ND, Bridgewater D. The Journal of Histochemistry and Cytochemistry. 2015 Jan;63(1):32-44.

Renal Branching Morphogenesis: Morphogenetic and Molecular Mechanisms. Blake J, Rosenblum ND. Seminars in Cell and Developmental Biology. 2014 Dec;36:2-12.

Patching the Pipeline: Creation and Retention of the Next Generation of Physician – Scientists for Child Health Research. Cornfield DN, Lane R, Rosenblum ND, Hostetter M, Jobe A, Albertine K, Aschner J, Abman SH. The Journal of Paediatrics. 2014 Nov;165(5):882-4.

Challenges Facing Physician Scientist Trainees: a Survey of Trainees in Canada’s Largest Undergraduate and Postgraduate Programs in a Single Centre. Balls BG, Rosenblum ND. Clinical and Investigative Medicine. 2014 Oct 4;37(5):E268-83.

Developmental Origins and Functions of Stromal Cells in the Normal and Diseased Mammalian Kidney.  Li W, Hartwig S, Rosenblum ND.  Developmental Dynamics. 2014 Jul;243(7):853-63.

Canadian Journal of Kidney Health and Disease: a unique launch of a unique journal. Levin A, Clase CM, Sood MM, Dicks E, Fortin MC, Hartwig S, Holden R, Lafrance JP, Molzahn A, Rosenblum ND, Samuel S, Soroka. Canadian Journal of Kidney Health and Disease. 2014 Apr 7;1:1.

A translational approach to congenital non-obstructive hydronephrosis. Thom RP, Rosenblum ND. Pediatric Nephrology. 2013 Sept; 28:1757-1761.

Alagille Syndrome: renal involvement and the role of the NOTCH signalling pathway. Kamath BM, Spinner NB, Rosenblum ND. Nature Reviews. Nephrology. 2013 Jul;9(7):409-18.

Kif3a Regulates Murine Nephron Number via GLI3 Repressor, Cell Survival, and Gene Expression in a Lineage-Specific Manner. Chi L, Galtseva A, Chen L, Mo R, Hui C-C, Rosenblum ND. PLoS One. 2013 Jun 7;8(6):e65448.

Visualizing renal primary cilia. Deane JA, Verghese E, Martelotto LG, Cain JE, Galtseva A, Rosenblum ND, Watkins DN, Ricardo SD. Nephrology. 2013 Mar;18(3):161-8.

Deletions in 16q24.2 are associated with autism spectrum disorder, intellectual disability, and congenital renal malformation. David Chitayat, Anath C. Lionel, Maury Pinsk, Andrea K Vaags, Christian R. Marshall, Sarah Dyack, Luis F. Escobar, Bridget A. Fernandez, Joseph C. Stegman, Jill A. Rosenfeld, Lisa G. Shaffer, McKinsey Goodenberger, Jennelle C. Hodge, Jason E. Cain, Riyana Babul-Hirji, Dimitri J. Stavropoulos, Megan E. Tucker, Verna Yiu, Stephen W. Scherer, Rosenblum ND. Journal of Medical Genetics. 2013 Mar;50(3):163-73.

Investigating primary cilia in cultured metanephric mesenchyme cells. Chi L, Rosenblum ND. Methods in Molecular Biology. 2012;886:157-63.

Going beyond Kirkpatrick in evaluating a clinician scientist program: it’s not “if it works” but “how it works”. Parker K, Burrows G, Nash H, Rosenblum ND. Academic Medicine: Journal of the Association of American Medical Colleges. 2011 Nov;86(11):1389-96.

The 11th International Workshop in Developmental Nephrology (IWDN). Rosenblum ND. Pediatric Nephrology. 2011 Sep;26(9):1363-4.

Control of mammalian kidney development by the Hedgehog signaling pathway. Cain JE, Rosenblum ND. Pediatric Nephrology. 2011 Sep;26(9):1365-71.

Alk3 controls nephron number and androgen production via lineage-specific effects in intermediate mesoderm. Di Giovanni V, Alday A, Chi L, Mishina Y, Rosenblum ND. Development. 2011 Jul;138(13):2717-27.

The GDNF target VSNL1 marks the ureteric tip. Ola R, Jakobson M, Perälä N, Kuure S, Braunewell K-H, Bridgewater D, Rosenblum ND, Sainio K, Sariola H. Journal of the American Society of Nephrology. 2011 Feb;22(2):274-84.

GLI3 Repressor controls functional development of the mouse ureter. Cain JE, Islam E, Haxho F, Blake J, Rosenblum ND. The Journal of Clinical Investigation. 2011 Mar;121(3):1199-206.

Suppressor of Fused Controls Mid-Hindbrain Patterning and Cerebellar Morphogenesis Via GLI3 Repressor. Kim JJ, Gill PS, Rotin L, van Eede M, Henkelman M, Hui CC, Rosenblum ND. The Journal of Neuroscience: The Official Journal of the Society of Neuroscience. 2011 Feb 2;31(5):1825-36.

b-catenin causes renal dysplasia via upregulation of TGFb2 and Dkk1. Bridgewater DB, Di Giovanni V, Cain JE, Cox B, Jakobson M, Sainio K, Rosenblum ND. Journal of The American Society of Nephrology. 2011 Apr;22(4):718-31.

 

 

 

Integrin linked kinase regulates p38MAPK-dependent cell cycle arrest in ureteric bud development. Smeeton J, Zhang X, Bulus N, Mernaugh G, Lange L, Karner CM, Carroll TJ, Fässler R, Pozzi A, Rosenblum ND, Zent R. Development. 2010 Oct;137(19):3233-43.

Genetics of Renal Hypoplasia: Insights into the Mechanisms Controlling Nephron Endowment. Cain JE, Di Giovanni V, Smeeton J, Rosenblum ND. Pediatric Research. 2010 Aug;68(2):91-8.

A Scientist Track Investigator Program to Support Early Career Outcomes for Clinician Scientists. Rosenblum ND, Bazett-Jones D, O’Brodovich H. The Journal of Paediatrics. 2009 Nov;155(5):603-4.e1.

GLI3 repressor controls nephron number via regulation of Wnt11 and Ret in Ureteric Tip Cells. Cain, JE, Islam E, Haxho F, Chen L, Bridgewater D, Nieuwenhuis E, Hui CC, Rosenblum ND. PLoS One. 2009 Oct 7;4(10):e7313.

Stimulatory and inhibitory signaling molecules that regulate renal branching morphogenesis. Bridgewater D, Rosenblum ND. Pediatric Nephrology. 2009 Sep;24(9):1611-9.

Cell and molecular biology of kidney development. Reidy KJ, Rosenblum ND. Seminars in Nephrology. 2009 Jul;29(4):321-37.

Systems Biology of Autosomal Dominant Polycystic Kidney Disease (ADPKD): Computational Identification of Gene Expression Pathways and Integrated Regulatory Networks. Song X, Di Giovanni V, He N, Wang K, Ingram A, Rosenblum ND, York P. Human Molecular Genetics. 2009 Jul 1;18(13):2328-43.

 

Tubulointerstitial nephritis as an extraintestinal manifestation of Crohn’s Disease. Waters AM, Zachos M, Herzenberg AM, Harvey E, Rosenblum ND. Nature Clinic Practice. Nephrology. 2008 Dec;4(12):693-7.

Polycystin-1 C-terminal tail associates with b-catenin and inhibits canonical Wnt signaling. Lai M, Song X, Pluznick JL, Di Giovanni V, Merrick DM, Rosenblum ND, Chauvet V, Gottard CJ, Pei Y, Caplan MJ. Human Molecular Genetics. 2008 Oct 15;17(20):3105-17.

Bone morphogenetic protein signaling in the developing kidney: Present and Future. Cain JE, Hartwig S, Bertram JF, Rosenblum ND. Differentiation. 2008 Oct;76(8):831-42.

Developmental Biology of the Human Kidney. Rosenblum ND. Seminars in Fetal & Neonatal Medicine. 2008 Jun;13(3):125-32.

Defects in ciliary localization of Nek8 is associated with cytogenesis. Trapp M, Galtseva A, Manning D, Beier D, Rosenblum ND, Quarmby L. Pediatric Nephrology. 2008 Mar;23(3):377-87.

The BMP receptor ALK3 controls collecting system formation during murine kidney development. Hartwig S, Bridgewater D, Cain J, DiGiovanni V, Mishina Y, Rosenblum ND. Journal of the American Society of Nephrology. 2008 Jan;19(1):117-24.

Performance of a career development and compensation program at an academic health sciences centre. O’Brodovich H, Beyene J, Tallett S, MacGregor D, Rosenblum ND. Pediatrics. 2007 Apr;119(4):e791-7.

Control of murine kidney development by Sonic Hedgehog and its GLI effectors. Gill PS, Rosenblum ND. Cell Cycle. 2006 Jul;5(13):1426-30.

GLI3-dependent transcriptional repression of Gli1 and Gli2 and kidney patterning genes disrupts renal morphogenesis. Hu MC, Mo R, Bhella S, Wilson CW, Chuang P-T, Hui CC, Rosenblum ND. Development. 2006 Feb;133(3):569-78.

Outcome of isolated antenatal hydronephrosis: a systematic review and meta-analysis. Sidhu G, Beyene J, Rosenblum NDPediatric Nephrology. 2006 Feb;21(2):218-24.

Shh controls epithelial proliferation via independent pathways that converge on N-Myc. Hu MC, Mo R, Bhella S, Wilson CW, Chuang P-T, Hui C-C, Rosenblum ND. Developmental Cell2005 Aug;9(2):293-303.

Outcome of isolated antenatal hydronephrosis: a systematic review and meta-analysis. Sidhu G, Beyene J, Rosenblum ND. Pediatric Nephrology. 2006 Feb;21(2):218-24.

Glypican-3 Modulates Inhibitory Bmp2-Smad Signaling to Control Renal Development in vivo. Hartwig S, Hu MC, Cella C, Piscione TD, Filmus J, Rosenblum ND. Mechanisms of Development.  2005 Jul;122(7-8):928-38.

Neonatal renal venous thrombosis: Clinical outcomes and Prevalence of prothrombotic disorders. Marks SD, Massicotte MP, Steele BT, Matsell DG, Filler G, Shah P, Perlman M, Rosenblum ND, Shah VS.The Journal of Pediatrics. 2005 Jun;146(6):811-6.

Integrin linked kinase mediates BMP7 dependent renal epithelial cell morphogenesis. Leung-Hagestejn C, Hu MC, Mahendra AS, Hartwig S, Klamut H, Rosenblum ND, Hannigan GE. Molecular and Cellular Biology. 2005 May;25(9):3648-57.

Smad1, b-catenin and TCF4 associate in a molecular complex with the c-MYC promoter in dysplastic renal tissue and cooperate to control c-MYC transcription. Hu MC, Rosenblum ND. Development. 2005 Jan;132(1):215-25.

HGF mediated renal epithelial branching morphogenesis is regulated by Glypican-4 expression. Karihaloo A, Kale S, Rosenblum ND, Cantley L. Molecular and Cellular Biology. 2004 Oct;24(19):8745-52.

Favourable outcome in patients with renal involvement complicating macrophage activation syndrome (MAS) in systemic onset JRA (SoJRA).  Ramanan AV, Rosenblum ND, Feldman BM, Laxer RM, Schneider R. Journal of Rheumatology. 2004 Oct;31(10):2068-70.

p38MAPK Acts in the BMP7-dependent stimulatory pathway during epithelial cell morphogenesis and is regulated by Smad1. Hu MC, Hartwig S, Wasserman D, Rosenblum ND. The Journal of Biological Chemistry. 2004 Mar 26;279(13):12051-9.

Outcome of isolated antenatal hydronephrosis. Cheng AM, Phan V, Geary DF, Rosenblum ND. Archives of Pediatric and Adolescent Medicine. 2004 Jan;158(1):38-40.

Prevalence of vesicoureteral reflux (VUR) in infants with isolated antenatal hydronephrosis (ANH): the role of post natal investigation. Phan V, Traubici J, Hershenfield B, Stephens D, Rosenblum ND, Geary D. Pediatric Nephrology. 2003 Dec;18(12):1224-8.

Genetic regulation of branching morphogenesis: lessons learned from loss-of-function phenotypes. Hu MC, Rosenblum ND. Pediatric Research. 2003 Oct;54(4):433-8.

Elevated Smad1/b-catenin molecular complexes and renal medullary dysplasia in ALK3 transgenic mice. Hu MC, Piscione TD, Rosenblum ND. Development. 2003 Jun;130(12):2753-66.

Hypercalciuria in Beckwith-Wiedemann Syndrome. Goldman M, Shuman C, Weksberg R, Rosenblum ND. Journal of Pediatrics. 2003 Feb;142(2):206-8.

Evaluation of a peer-reviewed career development and compensation programme for physicians at an academic health science centre. O’Brodovich H, Pleinys R, Laxer R, Tallett, S, Rosenblum ND, Sass-Kortsak C. Pediatrics. 2003 Jan;111(1):e26-31.

Molecular control of renal branching morphogenesis: current knowledge and emerging insights. Piscione TD, Rosenblum ND. Differentiation. 2002 Aug;70(6):227-46.

Renal abnormalities in Beckwith-Wiedemann Syndrome are associated with 11p.15.5 uniparental disomy. Goldman M, Smith A, Shuman C, Caluseiu O, Wei CH, Steele L, Ray P, Sadowski P, Squire J, Weksberg R, Rosenblum ND. Journal of the American Society of Nephrology. 2002 Aug;13(8):2077-84.

Endostatin regulates branching morphogenesis of renal epithelial cells and ureteric bud. Karihaloo A, Karumanchi SA, Barasch J, Jha V, Nickel CH, Yang J, Grisaru S, Bush KT, Nigam S, Rosenblum ND, Sukhatme VP, Cantley LG. Proceedings of the National Academy of Sciences of the United States of America. 2001 Oct 23;98(22):12509-14

Glypicans and the biology for renal malformations. Grisaru S, Rosenblum ND. Pediatric Nephrology. 2001 Mar;16(3):302-6.

Glypican-3 modulates BMP and FGF mediated effects during renal branching morphogenesis. Grisaru S, Cano-Gauci D, Tee J, Filmus J, Rosenblum ND. Developmental Biology. 2001 Mar 1;231(1):31-46.

p38MAPK acts in the BMP7-dependent stimulatory pathway during epithelial cell morphogenesis and is regulated by Smad1. Piscione TD, Phan T, Rosenblum ND. The Journal of Biological Chemistry. 2004 Mar 26;279(13):12051-9.

BMP2/ALK3 and HGF signal in parallel to regulate collecting duct morphogenesis. Gupta IR, Macias-Silva M, Kim S, Zhou X, Piscione TD, Whiteside C, Wrana JL, Rosenblum ND. Journal of Cell Science. 2000 Jan;113 Pt 2:269-78.

Vesicoureteric reflux (VUR) associated with renal dysplasia in the Wolf-Hirschhorn Syndrome (WHS). Ramage IJ, Grisaru S, Balfe WJ, Rosenblum ND. Pediatric Nephrology. 2000 Feb;14(2):146-8.

The Malformed Kidney: Disruption of Glomerular and Tubular Development. Piscione TD, Rosenblum ND. Clinical Genetics. 1999 Nov;56(5):341-56.

Protein kinase A is a negative regulator of renal branching morphogenesis and modulates inhibitory and stimulatory bone morphogenetic proteins. Gupta IR, Piscione TD, Grisaru S, Phan T, Macias-Silva M, Zhou X, Whiteside C, Wrana JL, Rosenblum ND. The Journal of Biological Chemistry. 1999 Sep 10;274(37):26305-14.

Glypican-3-deficient mice exhibit developmental overgrowth and some of the abnormalities typical of Simpson-Golabi-Behmel syndrome. Cano-Gauci DF, Yang H, McKerlie C,  Choo B, Shi W, Pullano R, Grisaru S, Piscione TD, Soon S, Wong, Z-M, Song H,  Sedlackova L, Tanswell AK, Mak TW, Yeger H, Rosenblum ND, Films J. The Journal of Cell Biology. 1999 Jul 12;146(1):255-64.v

Bone morphogenetic protein -2 and osteogenic protein -1 exert direct and opposite effects on renal branching morphogenesis. Piscione TD, Yager TD, Gupta IR, Grinfeld B, Pei Y, Attisano L, Wrana JL, Rosenblum ND. The American Journal of Physiology. 1997 Dec;273(6 Pt 2):F961-75.

Changing Patterns of Gene Expression in Developing Mouse Kidney, as Probed by Differential mRNA Display, Combined with cDNA Library Screening. Rosenblum ND, Yager TD. Kidney International. 1997 Mar;51(3):920-5.

Recombinant Alpha 1(VIII) Collagen Chains Form Homotrimers In Vitro. Rosenblum ND. Biochemical and Biophysical Research Communications. 1996 Oct 3;227(1):205-10.

Spontaneous Resolution Of Bilateral Upper Urinary Tract Obstruction in an Anuric Premature Neonate. Gupta IR, Chait P, Rosenblum ND. Pediatric Nephrology. 1996 Aug;10(4):544-5.

Expression of a Xenopus counterpart of mammalian syndecan 2 during embryogenesis. Rosenblum ND, Botelho BB, Bernfield M. The Biochemical Journal1995 Jul 1;309 ( Pt 1):69-76.

The pedagogic characteristics of a clinical conference for senior residents and faculty. Rosenblum ND, Nagler J, Lovejoy FH, Hafler JP. Archives of Pediatric and Adolescent Medicine. 1995 Sep;149(9):1023-8.

The Mesangial Matrix in the Normal and Sclerotic Glomerulus. Rosenblum ND. Kidney International. 1994 Feb;45:S73-7.

Predicting Medical Student Success in a Clinical Clerkship by Rating Students’ Nonverbal Behaviour. Rosenblum ND, Wetzel M, Platt, Daniels S, Crawford J, Rosenthal R. Archives of Pediatrics and Adolescent Medicine. 1994 Feb;148(2):213-9.

Alpha I(VIII) Collagen is Expressed in the Rat Glomerulus and in Resident Glomerular Cells. Rosenblum ND, Briscoe DM, Karnovsky MJ, Olsen BR. American Journal of Physiology. 1993 Jun;264(6 Pt 2):F1003-10.

A 13 Year-Old Girl with Gross Hematuria Four Years After a Diagnosis of Idiopathic Pulmonary Hemosiderosis. Rosenblum ND, Colvin RB.  The New England Journal of Medicine. 1993 Apr 22;328(16):1183-90.

Effect of Context on the Rating of Students by Faculty and Housestaff in a Clinical Clerkship. Rosenblum ND, Wetzel M, Platt O, Rosenthal R. Academic Medicine. Journal of The Association of American Medical Colleges. 1992 Jul;67(7):485.

Developmental Stage and Site Specific Expression of Collagen I and XII mRNA’s in The Rat Periodontal Ligament. Karimbux NY, Rosenblum ND, Nishimura I. Journal of Dental Research. 1992 Jul;71(7):1355-62.

Non-fibrillar collagenous proteins synthesized by rat mesangial cells. Rosenblum ND, Karnovsky MJ, Olsen BR. Journal of The American Society of Nephrology. 1990 Nov;1(5):785-91.

The type X collagen gene. Intron sequences split the 5′-untranslated region and separate the coding regions for the non-collagenous amino-terminal and triple-helical domains. LuValle P, Ninomiya Y, Rosenblum ND, Olsen BR. The Journal of Biological Chemistry. 1988 Dec 5;263(34):18378-85.

Treatment of chronic renal allograft rejection with cyclosporine and prednisone. Rosenblum ND, Harmon WE, Levey RH. Transplantation. 1988 Jan;45(1):232-4.

Pyloric stenosis and eosinophilic gastroenteritis in infants. Snyder JD, Rosenblum ND, Wershil B, Goldman H, Winter HS. Journal of Pediatric Gastroenterology and Nutrition. 1987 Jul-Aug;6(4):543-7.

Steroid effects on the course of abdominal pain in children with Henoch-Schonlein purport. Rosenblum ND, Winter HS. Pediatrics. 1987 Jun;79(6):1018-21.

2020

Transforming growth factor beta signaling functions during mammalian kidney development. Dumbrava MG, Lacanlale JL, Rowan CJ, Rosenblum ND. Pediatric Nephrology. 2020 Sep 3. Review.

Suppressor of fused controls cerebellum granule cell proliferation by suppressing Fgf8 and spatially regulating Gli proteins. Jiwani T, Kim JJ, Rosenblum ND. Development. 2020 Feb 3;147(3):dev170274.

 

2019

Precision Health Resource of Control iPSC Lines for Versatile Multilineage Differentiation. Hildebrandt MR, Reuter MS, Wei W, Tayebi N, Liu J, Sharmin S, Mulder J, Lesperance LS, Brauer PM, Mok RSF, Kinnear C, Piekna A, Romm A, Howe J, Pasceri P, Meng G, Rozycki M, Rodrigues DC, Martinez EC, Szego MJ, Zúñiga-Pflücker JC, Anderson MK, Prescott SA, Rosenblum ND, Kamath BM, Mital S, Scherer SW, Ellis J. Stem Cell Reports. 2019 Dec 10;13(6):1126-1141.

Generation of infant- and pediatric-derived urinary induced pluripotent stem cells competent to form kidney organoids. Mulder J, Sharmin S, Chow T, Rodrigues DC, Hildebrandt MR, D’Cruz R, Rogers I, Ellis J, Rosenblum ND. Pediatric Research. 2019 Oct 19.

Building a Professional Identity and an Academic Career Track in Translational Medicine. van Dijk SJ, Domenighetti AA, Gomez-Ospina N, Hunter P, Lindemans CA, Melotte V, van Rossum AMC, Rosenblum ND. Frontiers in Medicine. 2019 Jul 3;6:151.

Critical Gaps in Understanding the Clinician-Scientist Workforce: Results of an International Expert Meeting. Weggemans MM, Friesen F, Kluijtmans M, Prakken B, Ten Cate O, Woods NN, Rosenblum ND; International Expert Group on the Clinician-Scientist Workforce. Academic Medicine. 2019 May 21.

The Integration of Clinical and Research Training: How and Why MD-PhD Programs Work. Ng E, Jones AA, Sivapragasam M, Nath S, Mak LE, Rosenblum ND. Academic Medicine. 2019 May;94(5):664-670.

Impaired SIRT1 activity leads to diminution in glomerular endowment without accelerating age-associated GFR decline. Bellin AR, Zhang Y, Thai K, Rosenblum ND, Cullen-McEwen LA, Bertram JF, Gilbert RE. Physiological Reports. 2019 May;7(9):e14044.

Lineage-specific roles of hedgehog-GLI signaling during mammalian kidney development. D’Cruz R, Stronks K, Rowan CJ, Rosenblum ND. Pediatric Nephrology. 2019 Mar 28. Review.

2018

Preventing Translational Scientists From Extinction: The Long-Term Impact of a Personalized Training Program in Translational Medicine on the Careers of Translational Scientists. Weggemans MM, van der Schaaf M, Kluijtmans M, Hafler JP, Rosenblum ND, Prakken BJ. Frontiers in Medicine. (Lausanne). 2018 Nov 9;5:298.

Hedgehog-GLI signaling in Foxd1-positive stromal cells promotes murine nephrogenesis via TGFβ signaling. Rowan CJ, Li W, Martirosyan H, Erwood S, Hu D, Kim YK, Sheybani-Deloui S, Mulder J, Blake J, Chen L, Rosenblum ND. Development. 2018 Jul 9;145(13).

Predictors of sustained research involvement among MD/PhD programme graduates. Skinnider MA, Twa DDW, Squair JW, Rosenblum ND, Lukac CD; Canadian MD/PhD Program Investigation Group. Medical Education. 2018 May;52(5):536-545.

Protein Kinase 2β Is Expressed in Neural Crest-Derived Urinary Pacemaker Cells and Required for Pyeloureteric Contraction. Iskander SM, Feeney MM, Yee K, Rosenblum ND. Journal of American Society of Nephrology 2018 Apr;29(4):1198-1209.

Activated Hedgehog-GLI Signaling Causes Congenital Ureteropelvic Junction Obstruction. Sheybani-Deloui S, Chi L, Staite MV, Cain JE, Nieman BJ, Henkelman RM, Wainwright BJ, Potter SS, Bagli DJ, Lorenzo AJ, Rosenblum ND. Journal of American Society of Nephrology. 2018 Feb;29(2):532-544.

The Rising Challenge of Training Physician-Scientists: Recommendations From a Canadian National Consensus Conference. Strong MJ, Busing N, Goosney DL, Harris KA, Horsley T, Kuzyk A, Lingard L, Norman WV, Rosenblum ND, Saryeddine T, Wang X. Academic Medicine. 2018 Feb;93(2):172-178.

Canadians Seeking Solutions and Innovations to Overcome Chronic Kidney Disease (Can-SOLVE CKD): Form and Function. Levin A, Adams E, Barrett BJ, Beanlands H, Burns KD, Chiu HH, Chong K, Dart A, Ferera J, Fernandez N, Fowler E, Garg AX, Gilbert R, Harris H, Harvey R, Hemmelgarn B, James M, Johnson J, Kappel J, Komenda P, McCormick M, McIntyre C, Mahmud F, Pei Y, Pollock G, Reich H, Rosenblum ND, Scholey J, Sochett E, Tang M, Tangri N, Tonelli M, Turner C, Walsh M, Woods C, Manns B. Canadian Journal of Kidney Health Disease. 2018 Jan 17;5:2054358117749530.

Suppressor of fused controls cerebellar neuronal differentiation in a manner modulated by GLI3 repressor and Fgf15. Kim JJ, Jiwani T, Erwood S, Loree J, Rosenblum ND. Developmental Dynamics. 2018 Jan;247(1):156-169.

2017

Characteristics and outcomes of Canadian MD/PhD program graduates: a cross-sectional survey. Skinnider MA, Squair JW, Twa DDW, Ji JX, Kuzyk A, Wang X, Steadman PE, Zaslavsky K, Dey AK, Eisenberg MJ, Gagné ÈR, HayGlass KT, Lewis JF, Margetts PJ, Underhill DA, Rosenblum ND, Raymond LA. CMAJ Open. 2017 Apr 25;5(2):E308-E314.

Origin and Function of the Renal Stroma in Health and Disease. Rowan CJ, Sheybani-Deloui S, Rosenblum ND. Results & Problems in Cell Differentiation. 2017;60:205-229.

2016

Developing translational medicine professionals: the Marie Skłodowska-Curie action model. Petrelli A, Prakken BJ, Rosenblum ND; EUtrain Fellows. Journal of Translational Medicine. 2016 Nov 29;14(1):329.

The path ahead for MD/PhD programs in Canada Commentary on Jones et al. Rosenblum ND. Clinical and Investigative Medicine. 2016 Sep 11;39(4):E140-1.

Research projects in the Surgeon-Scientist and Clinician-Investigator programs at the University of Toronto (1987-2016): a cohort study. Goldenberg NM, Steinberg BE, Rutka JT, Chen R, Cabral V, Rosenblum ND, Kapus A, Lee WL. CMAJ Open. 2016 Aug 22;4(3):E444-E447.

Professional Identity Formation and the Clinician Scientist: A Paradigm for a Clinical Career Combining Two Distinct Disciplines. Rosenblum ND, Kluijtmans M, Ten Cate O. Academic Medicine. 2016 May 31. Epub ahead of print.

Integrin-Linked-Kinase Controls Renal Branching Morphogenesis via Dual Specificity Phosphatase 8.  Smeeton J, Dhir P, Hu D, Feeney MM, Chen L, Rosenblum ND. Journal of the American Society of Nephrology. 2016 May;27(5):1465-77.

Uropathogenic E.coli (UPEC) infection induces proliferation through Enhancer of Zeste Homologue 2 (EZH2). Ting K, Aitken KJ, Penna F, Samiei AN, Sidler M, Jiang J-X, Ibrahim F, Tolg C, Delgado-Olguin P, Rosenblum ND, Bagli DJ. PLoS One. 2016 Mar 10;11(3):e0149118.

Urogenital Development in Pallister-Hall Syndrome is Disrupted in a Cell Lineage-Specific Manner by Constitutive Expression of GLI3 Repressor.  Blake J, Hu D, Rosenblum ND.  Human Molecular Genetics. 2016 Feb 1;25(3):437-47.

2015

A New Grading System for the Management of Antenatal Hydronephrosis in Children. Dos Santos J, Parekh RS, Hassouna T, Figueroa V, Zhang Y, Salei A, Gonima P, Vargas I, Piscione TD, Farhat W, Rosenblum ND. Clinical Journal of the American Society of Nephrology. 2015 Oct 7;10(10):1783-90.

Blueprint for Action: Visioning Summit on the Future of the Workforce in Pediatrics. Sectish TC, Hay WW, Mahan JD, Mendoza FS, Spector ND, Stanton B, Szilagyi PG, Turner TL, Walker LR, and Slaw K.  Members of the Federation of Pediatric Organizations’ Visioning Summit Working Groups and Planning Committee. Pediatrics. 2015 Jul;136(1):161-9.

Insights into the renal pathogenesis in Schimke-immuno-osseous dysplasia: A renal histological characterization and expression analysis. Sarin S, Javidan A, Alexopoulou I, Svajger B, Boivin F, Chu S, Baradaran-Heravi A, Boerkoel CF, Rosenblum ND, Bridgewater D. The Journal of Histochemistry and Cytochemistry. 2015 Jan;63(1):32-44.

2014

Renal Branching Morphogenesis: Morphogenetic and Molecular Mechanisms. Blake J, Rosenblum ND. Seminars in Cell and Developmental Biology. 2014 Dec;36:2-12.

Patching the Pipeline: Creation and Retention of the Next Generation of Physician – Scientists for Child Health Research. Cornfield DN, Lane R, Rosenblum ND, Hostetter M, Jobe A, Albertine K, Aschner J, Abman SH. The Journal of Paediatrics. 2014 Nov;165(5):882-4.

Challenges Facing Physician Scientist Trainees: a Survey of Trainees in Canada’s Largest Undergraduate and Postgraduate Programs in a Single Centre. Balls BG, Rosenblum ND. Clinical and Investigative Medicine. 2014 Oct 4;37(5):E268-83.

Developmental Origins and Functions of Stromal Cells in the Normal and Diseased Mammalian Kidney.  Li W, Hartwig S, Rosenblum ND.  Developmental Dynamics. 2014 Jul;243(7):853-63.

Canadian Journal of Kidney Health and Disease: a unique launch of a unique journal. Levin A, Clase CM, Sood MM, Dicks E, Fortin MC, Hartwig S, Holden R, Lafrance JP, Molzahn A, Rosenblum ND, Samuel S, Soroka. Canadian Journal of Kidney Health and Disease. 2014 Apr 7;1:1.

2013

A translational approach to congenital non-obstructive hydronephrosis. Thom RP, Rosenblum ND. Pediatric Nephrology. 2013 Sept; 28:1757-1761.

Alagille Syndrome: renal involvement and the role of the NOTCH signalling pathway. Kamath BM, Spinner NB, Rosenblum ND. Nature Reviews. Nephrology. 2013 Jul;9(7):409-18.

Kif3a Regulates Murine Nephron Number via GLI3 Repressor, Cell Survival, and Gene Expression in a Lineage-Specific Manner. Chi L, Galtseva A, Chen L, Mo R, Hui C-C, Rosenblum ND. PLoS One. 2013 Jun 7;8(6):e65448.

Visualizing renal primary cilia. Deane JA, Verghese E, Martelotto LG, Cain JE, Galtseva A, Rosenblum ND, Watkins DN, Ricardo SD. Nephrology. 2013 Mar;18(3):161-8.

Deletions in 16q24.2 are associated with autism spectrum disorder, intellectual disability, and congenital renal malformation. David Chitayat, Anath C. Lionel, Maury Pinsk, Andrea K Vaags, Christian R. Marshall, Sarah Dyack, Luis F. Escobar, Bridget A. Fernandez, Joseph C. Stegman, Jill A. Rosenfeld, Lisa G. Shaffer, McKinsey Goodenberger, Jennelle C. Hodge, Jason E. Cain, Riyana Babul-Hirji, Dimitri J. Stavropoulos, Megan E. Tucker, Verna Yiu, Stephen W. Scherer, Rosenblum ND. Journal of Medical Genetics. 2013 Mar;50(3):163-73.

2012

Investigating primary cilia in cultured metanephric mesenchyme cells. Chi L, Rosenblum ND. Methods in Molecular Biology. 2012;886:157-63.

2011

Going beyond Kirkpatrick in evaluating a clinician scientist program: it’s not “if it works” but “how it works”. Parker K, Burrows G, Nash H, Rosenblum ND. Academic Medicine: Journal of the Association of American Medical Colleges. 2011 Nov;86(11):1389-96.

The 11th International Workshop in Developmental Nephrology (IWDN). Rosenblum ND. Pediatric Nephrology. 2011 Sep;26(9):1363-4.

Control of mammalian kidney development by the Hedgehog signaling pathway. Cain JE, Rosenblum ND. Pediatric Nephrology. 2011 Sep;26(9):1365-71.

Alk3 controls nephron number and androgen production via lineage-specific effects in intermediate mesoderm. Di Giovanni V, Alday A, Chi L, Mishina Y, Rosenblum ND. Development. 2011 Jul;138(13):2717-27.

The GDNF target VSNL1 marks the ureteric tip. Ola R, Jakobson M, Perälä N, Kuure S, Braunewell K-H, Bridgewater D, Rosenblum ND, Sainio K, Sariola H. Journal of the American Society of Nephrology. 2011 Feb;22(2):274-84.

GLI3 Repressor controls functional development of the mouse ureter. Cain JE, Islam E, Haxho F, Blake J, Rosenblum ND. The Journal of Clinical Investigation. 2011 Mar;121(3):1199-206.

Suppressor of Fused Controls Mid-Hindbrain Patterning and Cerebellar Morphogenesis Via GLI3 Repressor. Kim JJ, Gill PS, Rotin L, van Eede M, Henkelman M, Hui CC, Rosenblum ND. The Journal of Neuroscience: The Official Journal of the Society of Neuroscience. 2011 Feb 2;31(5):1825-36.

b-catenin causes renal dysplasia via upregulation of TGFb2 and Dkk1. Bridgewater DB, Di Giovanni V, Cain JE, Cox B, Jakobson M, Sainio K, Rosenblum ND. Journal of The American Society of Nephrology. 2011 Apr;22(4):718-31.

 

 

 

2010

Integrin linked kinase regulates p38MAPK-dependent cell cycle arrest in ureteric bud development. Smeeton J, Zhang X, Bulus N, Mernaugh G, Lange L, Karner CM, Carroll TJ, Fässler R, Pozzi A, Rosenblum ND, Zent R. Development. 2010 Oct;137(19):3233-43.

Genetics of Renal Hypoplasia: Insights into the Mechanisms Controlling Nephron Endowment. Cain JE, Di Giovanni V, Smeeton J, Rosenblum ND. Pediatric Research. 2010 Aug;68(2):91-8.

2009

A Scientist Track Investigator Program to Support Early Career Outcomes for Clinician Scientists. Rosenblum ND, Bazett-Jones D, O’Brodovich H. The Journal of Paediatrics. 2009 Nov;155(5):603-4.e1.

GLI3 repressor controls nephron number via regulation of Wnt11 and Ret in Ureteric Tip Cells. Cain, JE, Islam E, Haxho F, Chen L, Bridgewater D, Nieuwenhuis E, Hui CC, Rosenblum ND. PLoS One. 2009 Oct 7;4(10):e7313.

Stimulatory and inhibitory signaling molecules that regulate renal branching morphogenesis. Bridgewater D, Rosenblum ND. Pediatric Nephrology. 2009 Sep;24(9):1611-9.

Cell and molecular biology of kidney development. Reidy KJ, Rosenblum ND. Seminars in Nephrology. 2009 Jul;29(4):321-37.

Systems Biology of Autosomal Dominant Polycystic Kidney Disease (ADPKD): Computational Identification of Gene Expression Pathways and Integrated Regulatory Networks. Song X, Di Giovanni V, He N, Wang K, Ingram A, Rosenblum ND, York P. Human Molecular Genetics. 2009 Jul 1;18(13):2328-43.

 

2008

Tubulointerstitial nephritis as an extraintestinal manifestation of Crohn’s Disease. Waters AM, Zachos M, Herzenberg AM, Harvey E, Rosenblum ND. Nature Clinic Practice. Nephrology. 2008 Dec;4(12):693-7.

Polycystin-1 C-terminal tail associates with b-catenin and inhibits canonical Wnt signaling. Lai M, Song X, Pluznick JL, Di Giovanni V, Merrick DM, Rosenblum ND, Chauvet V, Gottard CJ, Pei Y, Caplan MJ. Human Molecular Genetics. 2008 Oct 15;17(20):3105-17.

Bone morphogenetic protein signaling in the developing kidney: Present and Future. Cain JE, Hartwig S, Bertram JF, Rosenblum ND. Differentiation. 2008 Oct;76(8):831-42.

Developmental Biology of the Human Kidney. Rosenblum ND. Seminars in Fetal & Neonatal Medicine. 2008 Jun;13(3):125-32.

Defects in ciliary localization of Nek8 is associated with cytogenesis. Trapp M, Galtseva A, Manning D, Beier D, Rosenblum ND, Quarmby L. Pediatric Nephrology. 2008 Mar;23(3):377-87.

The BMP receptor ALK3 controls collecting system formation during murine kidney development. Hartwig S, Bridgewater D, Cain J, DiGiovanni V, Mishina Y, Rosenblum ND. Journal of the American Society of Nephrology. 2008 Jan;19(1):117-24.

Archive

Performance of a career development and compensation program at an academic health sciences centre. O’Brodovich H, Beyene J, Tallett S, MacGregor D, Rosenblum ND. Pediatrics. 2007 Apr;119(4):e791-7.

Control of murine kidney development by Sonic Hedgehog and its GLI effectors. Gill PS, Rosenblum ND. Cell Cycle. 2006 Jul;5(13):1426-30.

GLI3-dependent transcriptional repression of Gli1 and Gli2 and kidney patterning genes disrupts renal morphogenesis. Hu MC, Mo R, Bhella S, Wilson CW, Chuang P-T, Hui CC, Rosenblum ND. Development. 2006 Feb;133(3):569-78.

Outcome of isolated antenatal hydronephrosis: a systematic review and meta-analysis. Sidhu G, Beyene J, Rosenblum NDPediatric Nephrology. 2006 Feb;21(2):218-24.

Shh controls epithelial proliferation via independent pathways that converge on N-Myc. Hu MC, Mo R, Bhella S, Wilson CW, Chuang P-T, Hui C-C, Rosenblum ND. Developmental Cell2005 Aug;9(2):293-303.

Outcome of isolated antenatal hydronephrosis: a systematic review and meta-analysis. Sidhu G, Beyene J, Rosenblum ND. Pediatric Nephrology. 2006 Feb;21(2):218-24.

Glypican-3 Modulates Inhibitory Bmp2-Smad Signaling to Control Renal Development in vivo. Hartwig S, Hu MC, Cella C, Piscione TD, Filmus J, Rosenblum ND. Mechanisms of Development.  2005 Jul;122(7-8):928-38.

Neonatal renal venous thrombosis: Clinical outcomes and Prevalence of prothrombotic disorders. Marks SD, Massicotte MP, Steele BT, Matsell DG, Filler G, Shah P, Perlman M, Rosenblum ND, Shah VS.The Journal of Pediatrics. 2005 Jun;146(6):811-6.

Integrin linked kinase mediates BMP7 dependent renal epithelial cell morphogenesis. Leung-Hagestejn C, Hu MC, Mahendra AS, Hartwig S, Klamut H, Rosenblum ND, Hannigan GE. Molecular and Cellular Biology. 2005 May;25(9):3648-57.

Smad1, b-catenin and TCF4 associate in a molecular complex with the c-MYC promoter in dysplastic renal tissue and cooperate to control c-MYC transcription. Hu MC, Rosenblum ND. Development. 2005 Jan;132(1):215-25.

HGF mediated renal epithelial branching morphogenesis is regulated by Glypican-4 expression. Karihaloo A, Kale S, Rosenblum ND, Cantley L. Molecular and Cellular Biology. 2004 Oct;24(19):8745-52.

Favourable outcome in patients with renal involvement complicating macrophage activation syndrome (MAS) in systemic onset JRA (SoJRA).  Ramanan AV, Rosenblum ND, Feldman BM, Laxer RM, Schneider R. Journal of Rheumatology. 2004 Oct;31(10):2068-70.

p38MAPK Acts in the BMP7-dependent stimulatory pathway during epithelial cell morphogenesis and is regulated by Smad1. Hu MC, Hartwig S, Wasserman D, Rosenblum ND. The Journal of Biological Chemistry. 2004 Mar 26;279(13):12051-9.

Outcome of isolated antenatal hydronephrosis. Cheng AM, Phan V, Geary DF, Rosenblum ND. Archives of Pediatric and Adolescent Medicine. 2004 Jan;158(1):38-40.

Prevalence of vesicoureteral reflux (VUR) in infants with isolated antenatal hydronephrosis (ANH): the role of post natal investigation. Phan V, Traubici J, Hershenfield B, Stephens D, Rosenblum ND, Geary D. Pediatric Nephrology. 2003 Dec;18(12):1224-8.

Genetic regulation of branching morphogenesis: lessons learned from loss-of-function phenotypes. Hu MC, Rosenblum ND. Pediatric Research. 2003 Oct;54(4):433-8.

Elevated Smad1/b-catenin molecular complexes and renal medullary dysplasia in ALK3 transgenic mice. Hu MC, Piscione TD, Rosenblum ND. Development. 2003 Jun;130(12):2753-66.

Hypercalciuria in Beckwith-Wiedemann Syndrome. Goldman M, Shuman C, Weksberg R, Rosenblum ND. Journal of Pediatrics. 2003 Feb;142(2):206-8.

Evaluation of a peer-reviewed career development and compensation programme for physicians at an academic health science centre. O’Brodovich H, Pleinys R, Laxer R, Tallett, S, Rosenblum ND, Sass-Kortsak C. Pediatrics. 2003 Jan;111(1):e26-31.

Molecular control of renal branching morphogenesis: current knowledge and emerging insights. Piscione TD, Rosenblum ND. Differentiation. 2002 Aug;70(6):227-46.

Renal abnormalities in Beckwith-Wiedemann Syndrome are associated with 11p.15.5 uniparental disomy. Goldman M, Smith A, Shuman C, Caluseiu O, Wei CH, Steele L, Ray P, Sadowski P, Squire J, Weksberg R, Rosenblum ND. Journal of the American Society of Nephrology. 2002 Aug;13(8):2077-84.

Endostatin regulates branching morphogenesis of renal epithelial cells and ureteric bud. Karihaloo A, Karumanchi SA, Barasch J, Jha V, Nickel CH, Yang J, Grisaru S, Bush KT, Nigam S, Rosenblum ND, Sukhatme VP, Cantley LG. Proceedings of the National Academy of Sciences of the United States of America. 2001 Oct 23;98(22):12509-14

Glypicans and the biology for renal malformations. Grisaru S, Rosenblum ND. Pediatric Nephrology. 2001 Mar;16(3):302-6.

Glypican-3 modulates BMP and FGF mediated effects during renal branching morphogenesis. Grisaru S, Cano-Gauci D, Tee J, Filmus J, Rosenblum ND. Developmental Biology. 2001 Mar 1;231(1):31-46.

p38MAPK acts in the BMP7-dependent stimulatory pathway during epithelial cell morphogenesis and is regulated by Smad1. Piscione TD, Phan T, Rosenblum ND. The Journal of Biological Chemistry. 2004 Mar 26;279(13):12051-9.

BMP2/ALK3 and HGF signal in parallel to regulate collecting duct morphogenesis. Gupta IR, Macias-Silva M, Kim S, Zhou X, Piscione TD, Whiteside C, Wrana JL, Rosenblum ND. Journal of Cell Science. 2000 Jan;113 Pt 2:269-78.

Vesicoureteric reflux (VUR) associated with renal dysplasia in the Wolf-Hirschhorn Syndrome (WHS). Ramage IJ, Grisaru S, Balfe WJ, Rosenblum ND. Pediatric Nephrology. 2000 Feb;14(2):146-8.

The Malformed Kidney: Disruption of Glomerular and Tubular Development. Piscione TD, Rosenblum ND. Clinical Genetics. 1999 Nov;56(5):341-56.

Protein kinase A is a negative regulator of renal branching morphogenesis and modulates inhibitory and stimulatory bone morphogenetic proteins. Gupta IR, Piscione TD, Grisaru S, Phan T, Macias-Silva M, Zhou X, Whiteside C, Wrana JL, Rosenblum ND. The Journal of Biological Chemistry. 1999 Sep 10;274(37):26305-14.

Glypican-3-deficient mice exhibit developmental overgrowth and some of the abnormalities typical of Simpson-Golabi-Behmel syndrome. Cano-Gauci DF, Yang H, McKerlie C,  Choo B, Shi W, Pullano R, Grisaru S, Piscione TD, Soon S, Wong, Z-M, Song H,  Sedlackova L, Tanswell AK, Mak TW, Yeger H, Rosenblum ND, Films J. The Journal of Cell Biology. 1999 Jul 12;146(1):255-64.v

Bone morphogenetic protein -2 and osteogenic protein -1 exert direct and opposite effects on renal branching morphogenesis. Piscione TD, Yager TD, Gupta IR, Grinfeld B, Pei Y, Attisano L, Wrana JL, Rosenblum ND. The American Journal of Physiology. 1997 Dec;273(6 Pt 2):F961-75.

Changing Patterns of Gene Expression in Developing Mouse Kidney, as Probed by Differential mRNA Display, Combined with cDNA Library Screening. Rosenblum ND, Yager TD. Kidney International. 1997 Mar;51(3):920-5.

Recombinant Alpha 1(VIII) Collagen Chains Form Homotrimers In Vitro. Rosenblum ND. Biochemical and Biophysical Research Communications. 1996 Oct 3;227(1):205-10.

Spontaneous Resolution Of Bilateral Upper Urinary Tract Obstruction in an Anuric Premature Neonate. Gupta IR, Chait P, Rosenblum ND. Pediatric Nephrology. 1996 Aug;10(4):544-5.

Expression of a Xenopus counterpart of mammalian syndecan 2 during embryogenesis. Rosenblum ND, Botelho BB, Bernfield M. The Biochemical Journal1995 Jul 1;309 ( Pt 1):69-76.

The pedagogic characteristics of a clinical conference for senior residents and faculty. Rosenblum ND, Nagler J, Lovejoy FH, Hafler JP. Archives of Pediatric and Adolescent Medicine. 1995 Sep;149(9):1023-8.

The Mesangial Matrix in the Normal and Sclerotic Glomerulus. Rosenblum ND. Kidney International. 1994 Feb;45:S73-7.

Predicting Medical Student Success in a Clinical Clerkship by Rating Students’ Nonverbal Behaviour. Rosenblum ND, Wetzel M, Platt, Daniels S, Crawford J, Rosenthal R. Archives of Pediatrics and Adolescent Medicine. 1994 Feb;148(2):213-9.

Alpha I(VIII) Collagen is Expressed in the Rat Glomerulus and in Resident Glomerular Cells. Rosenblum ND, Briscoe DM, Karnovsky MJ, Olsen BR. American Journal of Physiology. 1993 Jun;264(6 Pt 2):F1003-10.

A 13 Year-Old Girl with Gross Hematuria Four Years After a Diagnosis of Idiopathic Pulmonary Hemosiderosis. Rosenblum ND, Colvin RB.  The New England Journal of Medicine. 1993 Apr 22;328(16):1183-90.

Effect of Context on the Rating of Students by Faculty and Housestaff in a Clinical Clerkship. Rosenblum ND, Wetzel M, Platt O, Rosenthal R. Academic Medicine. Journal of The Association of American Medical Colleges. 1992 Jul;67(7):485.

Developmental Stage and Site Specific Expression of Collagen I and XII mRNA’s in The Rat Periodontal Ligament. Karimbux NY, Rosenblum ND, Nishimura I. Journal of Dental Research. 1992 Jul;71(7):1355-62.

Non-fibrillar collagenous proteins synthesized by rat mesangial cells. Rosenblum ND, Karnovsky MJ, Olsen BR. Journal of The American Society of Nephrology. 1990 Nov;1(5):785-91.

The type X collagen gene. Intron sequences split the 5′-untranslated region and separate the coding regions for the non-collagenous amino-terminal and triple-helical domains. LuValle P, Ninomiya Y, Rosenblum ND, Olsen BR. The Journal of Biological Chemistry. 1988 Dec 5;263(34):18378-85.

Treatment of chronic renal allograft rejection with cyclosporine and prednisone. Rosenblum ND, Harmon WE, Levey RH. Transplantation. 1988 Jan;45(1):232-4.

Pyloric stenosis and eosinophilic gastroenteritis in infants. Snyder JD, Rosenblum ND, Wershil B, Goldman H, Winter HS. Journal of Pediatric Gastroenterology and Nutrition. 1987 Jul-Aug;6(4):543-7.

Steroid effects on the course of abdominal pain in children with Henoch-Schonlein purport. Rosenblum ND, Winter HS. Pediatrics. 1987 Jun;79(6):1018-21.