Ureteric outgrowth imaged in urogenital culture

Embryonic mouse kidney explant cultured for 48 hours, then stained for Cytokeratin to mark ureteric branches. Imaged using Lightsheet Microscopy.

Image of mouse kidney stained with antibodies against Endomucin (vasculature) and SIX2 (nephrogenic cells)

Mouse kidney stained with antibodies against Endomucin (vasculature) and SIX2 (nephrogenic cells)

Image of mouse ureter stained with antibodies against smooth muscle actin and urinary pacemaker cells

Mouse ureter stained with antibodies against smooth muscle actin and urinary pacemaker cells

Kidney stained for LTL (green) and Endomucin (red)

Ex vivo assay demonstrating pyeloureteric contractions

Kidney stained for Vimentin (green) and Sall1 (red)

Image of embryonic kidney explant stained with antibodies against WT1 (red) and SIX2 (green)

Embryonic kidney explant stained with antibodies against WT1 (red) and SIX2 (green)

Image of kidney stained with antibodies against Sall1 (green) and PBX1 (pink)

Kidney stained with antibodies against Sall1 (green) and PBX1 (pink)

Kidney organoid section stained for WT1 (blue), LTL (green) and ECAD (red)

Kidney organoid stained with WT1 and E-cadherin antibodies. Organoid imaged using Lightsheet Microscopy.

Control Organoid stained for WT1, ECAD, DAPI

Kidney organoid stained for WT1, E-cadherin and DAPI

E13.5 kidney stained with SIX2 (green) and NCAM (red)

Image of kidney explant stained with antibodies against E-cadherin (green) and WT1 (red)

Kidney explant stained with antibodies against E-cadherin (green) and WT1 (red)

E13.5 kidney stained for SOX9 (branches)