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Paediatric Neuroinflammatory Disorders Program
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OUR RESEARCH
ALL STUDIES
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THERAPIES & OUTCOMES IN AUTOIMMUNE ENCEPHALOPATHY
OTHER STUDIES
CLINIC QUESTIONNAIRES: FAQ
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Publications
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2024
Can placebo-controlled phase 2 disease-modifying therapy trials in MS still be justified?
Assessment of dietary intake and its inflammatory potential in persons with pediatric-onset multiple sclerosis
Where does multiple sclerosis come from?
Real-life benefits of high-efficacy therapies for children with multiple sclerosis
OCT-Angiography in AQP4-positive NMOSD: finding subclinical disease using a new tool
Clinical features and outcomes in children with seronegative autoimmune encephalitis
Epstein-Barr Virus Strongly Associates With Pediatric Multiple Sclerosis, But Not Myelin Oligodendrocyte Glycoprotein-Antibody-Associated Disease
2023
Social network size and mental health outcomes in youth with neuroinflammatory disorders
Can we improve outcomes in MS around the world? Access and global considerations across income strata
Pediatric Multiple Sclerosis: Changing the Trajectory of Progression
Sleep, physical activity, and psychological outcomes in children and adolescents with pediatric onset multiple sclerosis
Beyond the B-cell as a treatment target in multiple sclerosis
Deviation From Normative Whole Brain and Deep Gray Matter Growth in Children With MOGAD, MS, and Monophasic Seronegative Demyelination
Delayed oculomotor response associates with optic neuritis in youth with demyelinating disorders
Multiple types of relapses in MOG antibody disease
Are we ready for CD19-targeted CAR T-cell therapies in MS?
2022
Linking X to MS: Immunity and demyelination on the X-chromosome in MS
High efficacy treatment is not enough in MS: Socioeconomic factors are key to improving outcomes
Implications of Low-Titer MOG Antibodies
Editorial: New Therapeutic Options for Rare Diseases
Diagnosis and Management of Opsoclonus-Myoclonus-Ataxia Syndrome in Children: An International Perspective
Structural visual metrics associate with moderate to vigorous physical activity in youth with pediatric onset neuroinflammatory disorders
2021
Infection-Related Myelopathies
It is time to move to alternative clinical trial designs: Reconsidering the holy grail of trial methodology
Lifestyle factors and outcomes in paediatric-onset multiple sclerosis
Longer-term Safety of B-Cell Therapy With Ocrelizumab in Multiple Sclerosis
Corrigendum: Pediatric NMOSD: A Review and Position Statement on Approach to Work-Up and Diagnosis
Physical Activity in Youth with Multiple Sclerosis receiving the ATOMIC intervention: Social connectedness above all else
2020
Could wider social networks prevent disability in MS and other neurologic disorders?
Tracking Therapies in MS: More Evidence in Favor of Neurofilament
2019
Improving outcomes in pediatric onset MS
Therapeutic plasma exchange in children with acute demyelination: kids are not small adults!
Vaccination: Not a trigger for MS.
Demyelinating lesions and progressive MS: location, location, location
Evolution of regional brain atrophy in children with multiple sclerosis: Gray matters
Family functioning among adolescents with narcolepsy.
Forecasting outcomes in anti-NMDAR encephalitis
A surface‐in gradient of thalamic damage evolves in pediatric multiple sclerosis
Live-cell based assays are the gold standard for anti-MOG-Ab testing
Abnormal effector and regulatory T cell subsets in paediatric-onset multiple sclerosis
Enhanced Recruitment During Executive Control Processing in Cognitively Preserved Patients With Pediatric-Onset MS.
Benefits of Physical Activity for Depression and Fatigue in Multiple Sclerosis: A Longitudinal Analysis.
Treatment of rituximab-associated chronic CNS enterovirus using IVIg and fluoxetine.
PANDAS/PANS in childhood: Controversies and evidence.
An upfront immunomodulatory therapy protocol for pediatric opsoclonus-myoclonus syndrome.
Clinical trials of disease-modifying agents in pediatric MS: Opportunities, challenges, and recommendations from the IPMSSG.
Depressive symptoms, sleep patterns, and physical activity in adolescents with narcolepsy.
Rituximab in children with myelin oligodendrocyte glycoprotein antibody and relapsing neuroinflammatory disease.
Early neuroaxonal injury is seen in the acute phase of pediatric optic neuritis.
Serial Anti-Myelin Oligodendrocyte Glycoprotein Antibody Analyses and Outcomes in Children With Demyelinating Syndromes.
Therapeutic plasma exchange in children with acute demyelination: Kids are not small adults!
Factors associated with health care utilization in pediatric multiple sclerosis.
Deep learning segmentation of orbital fat to calibrate conventional MRI for longitudinal studies.
2018
Incidence and prevalence of MS in children: A population-based study in Ontario, Canada.
Physical activity and dentate gyrus volume in pediatric acquired demyelinating syndromes.
Natural history and extracutaneous involvement of congenital morphea: Multicenter retrospective cohort study and literature review.
Radiologically isolated syndrome in children: Current knowledge and future directions.
Neuroimmune disorders of the central nervous system in children in the molecular era.
Acute Flaccid Paralysis and Enteroviral Infections.
Adherence in Youth With Multiple Sclerosis: A Qualitative Assessment of Habit Formation, Barriers, and Facilitators.
Evaluation of an Ophthalmoscopy Simulator to Teach Funduscopy Skills to Pediatric Residents.
Detection and clinical correlation of leukocortical lesions in pediatric-onset multiple sclerosis on multi-contrast MRI.
Lyme disease presenting with multiple cranial neuropathies on MRI.
Correction to: Impact of an electronic monitoring device and behavioural feedback on adherence to multiple sclerosis therapies in youth: results of a randomized trial.
MRI and laboratory features and the performance of international criteria in the diagnosis of multiple sclerosis in children and adolescents: a prospective cohort study.
Risk factors for non-adherence to disease-modifying therapy in pediatric multiple sclerosis.
Specific myelopathy diagnoses using advancing diagnostics
Involvement of the Amygdala in Memory and Psychosocial Functioning in Pediatric-Onset Multiple Sclerosis.
2017
Evaluation and treatment of Langerhans cell histiocytosis patients with central nervous system abnormalities: Current views and new vistas.
Radiologically isolated syndrome in children
A feasibility study of working memory training for individuals with paediatric-onset multiple sclerosis.
Impact of an electronic monitoring device and behavioral feedback on adherence to multiple sclerosis therapies in youth: results of a randomized trial
Monophasic demyelination reduces brain growth in children.
White matter changes in paediatric multiple sclerosis and monophasic demyelinating disorders.
Interferon-Stimulated Gene Expression as a Preferred Biomarker for Disease Activity in Aicardi-Goutières Syndrome.
The computer-based Symbol Digit Modalities Test: establishing age-expected performance in healthy controls and evaluation of pediatric MS patients.
Longitudinal Outcomes in the 2014 Acute Flaccid Paralysis Cluster in Canada.
Risk factors for non-adherence to disease-modifying therapy in pediatric multiple sclerosis
How to Treat Involvement of the Central Nervous System in Hemophagocytic Lymphohistiocytosis?
2016
The Changing Landscape of Childhood Inflammatory Central Nervous System Disorders
Physical Activity and Its Correlates in Youth with Multiple Sclerosis.
Cognitive and Behavioral Functioning in Childhood Acquired Demyelinating Syndromes.
Physical activity in pediatric onset multiple sclerosis: Validating a questionnaire for clinical practice and research.
Pediatric optic neuritis.
ROHHAD syndrome and evolution of sleep disordered breathing.
Canadian Paediatric Neurology Workforce Survey and Consensus Statement.
Contribution of the cerebellum to cognitive performance in children and adolescents with multiple sclerosis.
Long-Term Neurocognitive, Psychosocial, and Magnetic Resonance Imaging Outcomes in Pediatric-Onset Acute Disseminated Encephalomyelitis.
Fatigue in childhood multiple sclerosis
2015
The temporal evolution of structural and functional measures after acute optic neuritis.
Lower physical activity is associated with higher disease burden in pediatric multiple sclerosis.
Physical activity and pediatric multiple sclerosis: Developing a research agenda.
Recovery From Central Nervous System Acute Demyelination in Children.
Outcomes after early administration of plasma exchange in pediatric central nervous system inflammatory demyelination.
Evaluation of fall Sun Exposure Score in predicting vitamin D status in young Canadian adults, and the influence of ancestry.
2014
Rituximab as a first-line preventive treatment in pediatric NMOSDs: Preliminary results in 5 children.
Functional-structural correlations in the afferent visual pathway in pediatric demyelination.
Antinuclear antibodies in pediatric acquired demyelinating diseases of the central nervous system.
White matter changes in childhood NMDA receptor encephalitis
Multicystic demyelinating myelopathy: widening spectrum of pediatric aquaporin-4 autoimmunity.
Tract-based spatial statistics analysis of diffusion-tensor imaging data in pediatric- and adult-onset multiple sclerosis.
2013
2010 McDonald criteria in a pediatric cohort: is positivity at onset associated with a more aggressive multiple sclerosis course?
Glatiramer acetate-induced acute hepatotoxicity in an adolescent with MS.
Fatigue and depression in children with demyelinating disorders.
Antibody response to common viruses and human leukocyte antigen-DRB1 in pediatric multiple sclerosis.
Synthesis and analysis of the all-(S) side chain of phosphomycoketides: a test of NMR predictions for saturated oligoisoprenoid stereoisomers.
Iron content of the pulvinar nucleus of the thalamus is increased in adolescent multiple sclerosis.
Bare-minimum fluorous mixture synthesis of a stereoisomer library of 4,8,12-trimethylnonadecanols and predictions of NMR spectra of saturated oligoisoprenoid stereoisomers.
Reversible diffusion weighted imaging changes in propionic acidemia.
2012
No association between conventional brain MR imaging and chronic cerebrospinal venous insufficiency in multiple sclerosis.
The management of pediatric multiple sclerosis.
Management of children with multiple sclerosis.
Clinical correlates of chronic cerebrospinal venous insufficiency in multiple sclerosis.
Neurologic complications of 2009 influenza-a H1N1 infection in children.
Multiple sclerosis: Which MRI findings predict MS development in children?
Acuted disseminated encephalomyelitis.
Regression-based norms improve the sensitivity of the National MS Society Consensus Neuropsychological Battery for Pediatric Multiple Sclerosis (NBPMS).
Consensus statement: evaluation of new and existing therapeutics for pediatric multiple sclerosis.
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