Our Publications

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Mitina A, Khan M, Lesurf R, Yin Y, Engchuan W, Hamdan O, Pellecchia G, Trost B, Backstrom I, Guo K, Pallotto LM, Lam Doong PH, Wang Z, Nalpathamkalam T, Thiruvahindrapuram B, Papaz T, Pearson CE, Ragoussis J, Subbarao P, Azad MB, Turvey SE, Mandhane P, Moraes TJ, Simons E, Scherer SW, Lougheed J, Mondal T, Smythe J, Altamirano-Diaz L, Oechslin E, Mital S, Yuen RKC. Genome-wide enhancer-associated tandem repeats are expanded in cardiomyopathy. EBioMedicine. 2024 Mar;101:105027 [PubMed]

Conway J, Min S, Villa C, Weintraub RG, Nakano S, Godown J, Tatangelo M, Armstrong K, Richmond M, Kaufman B, Lal AK, Balaji S, Power A, Baez Hernandez N, Gardin L, Kantor PF, Parent JJ, Aziz PF, Jefferies JL, Dragulescu A, Jeewa A, Benson L, Russell MW, Whitehill R, Rossano J, Howard T, Mital S. The Prevalence and Association of Exercise Test Abnormalities With Sudden Cardiac Death and Transplant-Free Survival in Childhood Hypertrophic Cardiomyopathy. Circulation. 2023 Feb 28;147(9):718-727. [PubMed]

Vaisbourd Y, Dahhou M, Zhang X, Sapir-Pichhadze R, Cardinal H, Johnston O, Blydt-Hansen TD, Tibbles LA, Hamiwka L, Urschel S, Birk P, Bissonnette J, Matsuda-Abedini M, BScPhm JH, Schiff J, Phan V, De Geest S, Allen U, Avitzur Y, Mital S, Foster BJ. Differences in medication adherence by sex and organ type among adolescent and young adult solid organ transplant recipients. Pediatr Transplant. 2023 Mar;27(2):e14446. [PubMed]

Lewis MJ, Hsieh A, Qiao L, Tan R, Kazzi B, Channing A, Griffin EL, Jobanputra V, Su J, Shahryar C, Kochilas L, Gaynor JW, Lee T, Goldmuntz E, Russell M, Mital S, Tristani M, Brueckner M, Newburger J, Shen Y, Chung WK. Association of Predicted Damaging De Novo Variants on Ventricular Function in Individuals With Congenital Heart Disease. Circ Genom Precis Med. 2023 Apr;16(2):e003900. [PubMed]

Lynch A, Tatangelo M, Ahuja S, Steve Fan CP, Min S, Lafreniere-Roula M, Papaz T, Zhou V, Armstrong K, Aziz PF, Benson LN, Butts R, Dragulescu A, Gardin L, Godown J, Jeewa A, Kantor PF, Kaufman BD, Lal AK, Parent JJ, Richmond M, Russell MW, Balaji S, Stephenson EA, Villa C, Jefferies JL, Whitehill R, Conway J, Howard TS, Nakano SJ, Rossano J, Weintraub RG, Mital S. Risk of Sudden Death in Patients With RASopathy Hypertrophic Cardiomyopathy. J Am Coll Cardiol. 2023 Mar 21;81(11):1035-1045. [PubMed]

Oliveros W, Delfosse K, Lato DF, Kiriakopulos K, Mokhtaridoost M, Said A, McMurray BJ, Browning JWL, Mattioli K, Meng G, Ellis J, Mital S, Melé M, Maass PG. Systematic characterization of regulatory variants of blood pressure genes. Cell Genom. 2023 May 24;3(7):100330. [PubMed]

Tessler I, Albuisson J, Piñeiro-Sabarís R, Verstraeten A, Kamber Kaya HE, Siguero-Álvarez M, Goudot G, MacGrogan D, Luyckx I, Shpitzen S, Levin G, Kelman G, Reshef N, Mananet H, Holdcraft J, Muehlschlegel JD, Peloso GM, Oppenheim O, Cheng C, Mazzella JM, Andelfinger G, Mital S, Eriksson P, Billon C, Heydarpour M, Dietz HC, Jeunemaitre X, Leitersdorf E, Sprinzak D, Blacklow SC, Body SC, Carmi S, Loeys B, de la Pompa JL, Gilon D, Messas E, Durst R. Novel Association of the NOTCH Pathway Regulator MIB1 Gene With the Development of Bicuspid Aortic Valve. JAMA Cardiol. 2023 Aug 1;8(8):721-731. [PubMed]

Akinrinade O, Lesurf R; Genomics England Research Consortium; Lougheed J, Mondal T, Smythe J, Altamirano-Diaz L, Oechslin E, Mital S. Age and Sex Differences in the Genetics of Cardiomyopathy. J Cardiovasc Transl Res. 2023 Dec;16(6):1287-1302. [PubMed]

Malik A, Villalobos Lizardi JC, Baranger J, Venet M, Pernot M, Mital S, Nguyen MB, Chaturvedi R, Mertens L, Villemain O. Comparison Between Acoustic Radiation Force-Induced and Natural Wave Velocities for Myocardial Stiffness Assessment in Hypertrophic Cardiomyopathy. JACC Cardiovasc Imaging. 2023 Sep 7:S1936-878X(23)00384-4. [PubMed]

Blue EE, White JJ, Dush MK, Gordon WW, Wyatt BH, White P, Marvin CT, Helle E, Ojala T, Priest JR, Jenkins MM, Almli LM, Reefhuis J, Pangilinan F, Brody LC, McBride KL, Garg V, Shaw GM, Romitti PA, Nembhard WN, Browne ML, Werler MM, Kay DM; National Birth Defects Prevention Study; University of Washington Center for Mendelian Genomics; Mital S, Chong JX, Nascone-Yoder NM, Bamshad MJ. Rare variants in CAPN2 increase risk for isolated hypoplastic left heart syndrome. HGG Adv. 2023 Aug 12;4(4):100232. [PubMed]

Zahavich L, Akilen R, George K, Mital S. Heart Failure with Recovered Ejection Fraction in Patients with Vinculin Loss-of-function Variants. J Cardiovasc Transl Res. 2023 Dec;16(6):1303-1309. [PubMed]

Nguyen MB, Venet M, Steve Fan CP, Dragulescu A, Rusin CG, Mertens LL, Mital S, Villemain O. Modeling the relationship between diastolic phenotype and outcomes in pediatric hypertrophic cardiomyopathy. J Am Soc Echocardiogr. 2023 Dec 12:S0894-7317(23)00653-3. [PubMed]

Min S, Papaz T, Lambert AN, Allen U, Birk P, Blydt-Hansen T, Foster BJ, Grasemann H, Hamiwka L, Litalien C, Ng V, Berka N, Campbell P, Daniel C, Saw CL, Tinckam K, Urschel S, Van Driest SL, Parekh R, Mital S. An Integrated Clinical and Genetic Prediction Model for Tacrolimus Levels in Pediatric Solid Organ Transplant Recipients. Transplantation. 2022 Mar 1;106(3):597-606. [PubMed]

Škorić-Milosavljević D, Tadros R, Bosada FM, Tessadori F, van Weerd JH, Woudstra OI, Tjong FVY, Lahrouchi N, Bajolle F, Cordell HJ, Agopian AJ, Blue GM, Barge-Schaapveld DQCM, Gewillig M, Preuss C, Lodder EM, Barnett P, Ilgun A, Beekman L, van Duijvenboden K, Bokenkamp R, Müller-Nurasyid M; KORA-Study Group; Vliegen HW, Konings TC, van Melle JP, van Dijk APJ, van Kimmenade RRJ, Roos-Hesselink JW, Sieswerda GT, Meijboom F, Abdul-Khaliq H, Berger F, Dittrich S, Hitz MP, Moosmann J, Riede FT, Schubert S, Galan P, Lathrop M, Munter HM, Al-Chalabi A, Shaw CE, Shaw PJ, Morrison KE, Veldink JH, van den Berg LH, Evans S, Nobrega MA, Aneas I, Radivojkov-Blagojević M, Meitinger T, Oechslin E, Mondal T, Bergin L, Smythe JF, Altamirano-Diaz L, Lougheed J, Bouma BJ, Chaix MA, Kline J, Bassett AS, Andelfinger G, van der Palen RLF, Bouvagnet P, Clur SB, Breckpot J, Kerstjens-Frederikse WS, Winlaw DS, Bauer UMM, Mital S, Goldmuntz E, Keavney B, Bonnet D, Mulder BJ, Tanck MWT, Bakkers J, Christoffels VM, Boogerd CJ, Postma AV, Bezzina CR. Common Genetic Variants Contribute to Risk of Transposition of the Great Arteries. Circ Res. 2022 Jan 21;130(2):166-180. [PubMed]

Vaikom House AK, Chetan D, Mital S, Grosse-Wortmann L. Patients with repaired tetralogy of Fallot and the HIF1A1744C/T variant have increased imaging markers of diffuse myocardial fibrosis. Int J Cardiol. 2022 Mar 1;350:33-35. [PubMed]

Dave JM, Chakraborty R, Ntokou A, Saito J, Saddouk FZ, Feng Z, Misra A, Tellides G, Riemer RK, Urban Z, Kinnear C, Ellis J, Mital S, Mecham R, Martin KA, Greif DM. JAGGED1/NOTCH3 activation promotes aortic hypermuscularization and stenosis in elastin deficiency. J Clin Invest. 2022 Mar 1;132(5):e142338. [PubMed]

Dick SA, Wong A, Hamidzada H, Nejat S, Nechanitzky R, Vohra S, Mueller B, Zaman R, Kantores C, Aronoff L, Momen A, Nechanitzky D, Li WY, Ramachandran P, Crome SQ, Becher B, Cybulsky MI, Billia F, Keshavjee S, Mital S, Robbins CS, Mak TW, Epelman S. Three tissue resident macrophage subsets coexist across organs with conserved origins and life cycles. Sci Immunol. 2022 Jan 7;7(67):eabf7777. [PubMed]

Nguyen MB, Mital S, Mertens L, Jeewa A, Friedberg MK, Aguet J, Adler A, Lam CZ, Dragulescu A, Rakowski H, Villemain O. Pediatric Hypertrophic Cardiomyopathy: Exploring the Genotype-Phenotype Association. J Am Heart Assoc. 2022 Mar;11(5):e024220. [PubMed]

Lesurf R, Said A, Akinrinade O, Breckpot J, Delfosse K, Liu T, Yao R, Persad G, McKenna F, Noche RR, Oliveros W, Mattioli K, Shah S, Miron A, Yang Q, Meng G, Yue MCS, Sung WWL, Thiruvahindrapuram B, Lougheed J, Oechslin E, Mondal T, Bergin L, Smythe J, Jayappa S, Rao VJ, Shenthar J, Dhandapany PS, Semsarian C, Weintraub RG, Bagnall RD, Ingles J; Genomics England Research Consortium; Melé M, Maass PG, Ellis J, Scherer SW, Mital S. Whole genome sequencing delineates regulatory, copy number, and cryptic splice variants in early onset cardiomyopathy. NPJ Genom Med. 2022 Mar 14;7(1):18. [PubMed]

Meester JAN, Peeters S, Van Den Heuvel L, Vandeweyer G, Fransen E, Cappella E, Dietz HC, Forbus G, Gelb BD, Goldmuntz E, Hoskoppal A, Landstrom AP, Lee T, Mital S, Morris S, Olson AK, Renard M, Roden DM, Singh MN, Selamet Tierney ES, Tretter JT, Van Driest SL, Willing M, Verstraeten A, Van Laer L, Lacro RV, Loeys BL. Molecular characterization and investigation of the role of genetic variation in phenotypic variability and response to treatment in a large pediatric Marfan syndrome cohort. Genet Med. 2022 May;24(5):1045-1053. [PubMed]

Rumman RK, Slorach C, Hui W, Lopez C, Larios G, Fan S, Franco-Cereceda A, Loeys B, Mohamed SA, Dietz H, Mital S, Andelfinger G, Mertens L, Grattan M; Mechanistic Interrogation of Bicuspid Aortic Valve-associated Aortopathy (MIBAVA) Leducq Consortium. Regional Vascular Changes and Aortic Dilatation in Pediatric Patients With Bicuspid Aortic Valve. Can J Cardiol. 2022 May;38(5):688-694. [PubMed]

Jegathisawaran J, Tsiplova K, Hayeems RZ, Marshall CR, Stavropoulos DJ, Pereira SL, Thiruvahindrapuram B, Liston E, Reuter MS, Manshaei R, Cohn I, Jobling R, Kim RH, Mital S, Ungar WJ. Trio genome sequencing for developmental delay and pediatric heart conditions: A comparative microcost analysis. Genet Med. 2022 May;24(5):1027-1036. [PubMed]

Yu Z, Zhou X, Liu Z, Pastrana-Gomez V, Liu Y, Guo M, Tian L, Nelson TJ, Wang N, Mital S, Chitayat D, Wu JC, Rabinovitch M, Wu SM, Snyder MP, Miao Y, Gu M. KMT2D-NOTCH Mediates Coronary Abnormalities in Hypoplastic Left Heart Syndrome. Circ Res. 2022 Jul 22;131(3):280-282. [PubMed]

Pieles GE, Alkon J, Manlhiot C, Fan CPS, Kinnear C, Benson LN, Mital S, Friedberg MK. Association between genetic variants in the HIF1A-VEGF pathway and left ventricular regional myocardial deformation in patients with Hypertrophic Cardiomyopathy. Pediatric Research 2021; 89(3): 628-635. [PubMed]

Mawad W, Mertens L, Pagano JJ, Riesenkampff E, Reichert MJE, Mital S, Kantor PF, Greenberg M, Liu P, Nathan PC, Grosse-Wortmann L. Effect of Anthracycline Therapy on Myocardial Function and Markers of Fibrotic Remodelling in Childhood Cancer Survivors. Eur Heart J Cardiovasc Imaging 2021; 22(4): 435-442. [PubMed]

Mital S. A Pediatric Perspective on the ACC/AHA Hypertrophic Cardiomyopathy Guidelines. An Invited Expert Analysis for the American College of Cardiology Heart Failure and Cardiomyopathies Clinical Topic Collection. J Am Coll Cardiol 2021; www.acc.org/HFandCardiomyopathies. [PubMed]

Ommen SR (Chair), Mital S (Vice Chair), Burke MA, Day SM, Deswal A, Elliott P, Evanovich LL, Hung J, Joglar JA, Kantor P, Kimmelstiel C, Kittleson M, Link MS, Maron MS, Martinez MW, Miyake CY, Schaff HV, Semsarian C, Paul S. 2020 AHA/ACC Guideline for the Diagnosis and Treatment of Patients With Hypertrophic Cardiomyopathy: A Report of the American College of Cardiology/American Heart Association Joint Committee on Clinical Practice Guidelines. J Thorac Cardiovasc Surg 2021;162(1): e23-e106. [PubMed] 

Skoric-Milosavljevic D, Lahrouchi N, Bosada F, Dombrowsky G, Williams S, Lesurf R, Tjong F, Walsh R, El Bouchikhi I, Breckpot J*, Audain E, Ilgun A, Beekman L, Ratbi I, Strong A, Muenke M, Heidi S, Muir A, Hababa M, Cross L, Zhou D, Pastinen T, Zackai E, Atmani S, Ouldim K, Adadi N, Steindel K, Rauch A, Brook J, Wilsdon A, Kuipers I, Blom N, Mulder B, Mefford H, Keren B, Joset P, Kruszka P, Thiffault I, Sheppard S, Roberts A, Lodder E, Keavney B, Clur S-A B, Mital S, Hitz M-P, Christoffels V, Postma A, Bezzina C. Rare variants in KDR, encoding VEGF Receptor 2, are associated with tetralogy of Fallot. Genet in Medicine. 2021; 23(10):2013 https://doi.org/10.1038/s41436-021-01279-7. [PubMed]

Teekakirikul P, Zhu W, Gabriel GC, Young CB, Williams K, Martin LJ, Hill JC, Richards T, Billaud M, Phillippi JA, Wang J, Wu Y, Tan T, Devine W, Lin J-H, Bais AS, Klonowski J, de Bellaing AM, Saini A, Wang MX, Emerel L, Salamacha N, Wyman SK, Lee C, Li HS, Miron A, Zhang J, Xing J, McNamara DM, Fung E, Kirshbom P, Mahle W, Kochilas LK, He Y, Garg V, White P, McBride K, Benson DW, Gleason TG, Mital S, Lo CW. Common deletion variants causing protocadherin-a deficiency contribute to the complex genetics of bicuspid aortic valve and left-sided congenital heart disease. Human Genetics and Genomics Advances 2021; 2(3): 100037. [PubMed]

Dabirzadeh A,Dahhou M, Zhang X, Sapir-Pichhadze R, Cardinal H, White M, Johnston O, Blydt-Hansen T, Tibbles LA, Hamiwka L, Urschel S, Birk P, Matsuda-Abedini M, Phan V, De Geest S, Allen U, Mital S, Foster BJ. Care Processes and Structures Associated with Higher Medication Adherence in Adolescent and Young Adult Transplant Recipients. Pediatric Transplantation. 2021Aug 2:e14106. [PubMed]

Skoric-Milosavljevic D, Tadros R, Bosada F, Tessadori F, Weerd JV, Woudstra O,Tjong F, Lahrouchi N, Bajolle F, Cordell H, Agopian A.J., Blue G, Barge-Schaapveld D, Preuss C, Lodder E, Beekman L, Bokenkamp R, Müller-Nurasyid M, Vliegen H , Konings T, Melle JV, Dijk AV, Kimmenade RV, Roos-Hesselink J, Sieswerda G, Meijboom F, Abdul-Khaliq H, Berger F, Dittrich S, Hitz MP, Moosmann J, Riede FT, Schubert S, Galan P, Lathrop M, Munter H, Al-Chalabi A, Shaw C, Shaw P, Morrison K, Veldink J, van den Berg L, Radivojkov-Blagojevic M, Meitinger T, Oechslin E, Mondal T, Bergin L, Smythe J, Altamirano-Diaz L, Lougheed J, Bouma B, Chaix M*, Kline J, Bassett A, Andelfinger G, van der Palen R, Bouvagnet P, Clur SA, Breckpot J*, Kerstjens-Frederikse W, Winlaw D, Bauer U, Mital S, Goldmuntz E, Keavney B, Bonnet D, Mulder B, Tanck M, Bakkers J, Christoffels V, Postma A, Gewillig M, Bezzina C. Common genetic variants contribute to risk of transposition of the great arteries. Circulation Research 2021.[PubMed]

Diller GP, Arvanitaki A, Opotowsky AR, Jenkins K, Moons P, Kempny A, Tandon A, Redington A, Khairy P, Mital S, Gatzoulis MΑ, Li Y, Marelli A. Lifespan Perspective on Congenital Heart Disease Research: JACC State-of-the-Art Review. J Am Coll Cardiol. 2021 May 4;77(17):2219-2235. [PubMed]

Zaman R, Hamidzada H, Kantores C, Wong A, Dick SA, Wang Y, Momen A, Aronoff L, Lin J, Razani B, Mital S, Billia P, Lavine KJ, Nejat S, Epelman S. Selective loss of resident macrophage derived insulin-like growth factor-1 abolishes adaptive cardiac growth to stress. Immunity 2021: 54(9): 2057-2071. [PubMed]

  • Yao RA, Akinrinade O, Chaix M, Mital S. Quality of whole genome sequencing from blood versus saliva derived DNA in cardiac patients. BMC Med Genomics 2020 Jan 29;13(1):11. [PubMed]
  • Grattan M, Prince A, Rumman RK, Morgan C, Petrovic M, Hauck A, Young L, Franco-Cereceda A, Loeys B, Mohamed SA, Dietz H, Mital S, Fan CS, Manlhiot C, Andelfinger G, Mertens L. Predictors of Bicuspid Aortic Valve-Associated Aortopathy in Childhood: A Report From the MIBAVA Consortium. Circ Cardiovasc Imaging 2020 Mar;13(3):e009717. [PubMed]
  • Kinnear C, Agrawal R, Loo C, Pahnke A, Rodrigues DC, Thompson T, Akinrinade O, Ahadian S, Keeley F, Radisic M, Mital S, Ellis J. Everolimus Rescues the Phenotype of Elastin Insufficiency in Patient Induced Pluripotent Stem Cell-Derived Vascular Smooth Muscle Cells. Arterioscler Thromb Vasc Biol 2020 May;40(5):1325-1339. [PubMed]
  • Pieles GE, Alkon J, Manlhiot C, Fan CS, Kinnear C, Benson LN, Mital S, Friedberg MK. Association between genetic variants in the HIF1A-VEGF pathway and left ventricular regional myocardial deformation in patients with hypertrophic cardiomyopathy. Pediatr Res 2020 May 6. [PubMed]
  • Miron A, Lafreniere-Roula M, Steve Fan CP, Armstrong KR, Dragulescu A, Papaz T, Manlhiot C, Kaufman B, Butts RJ, Gardin L, Stephenson EA, Howard TS, Aziz PF, Balaji S, Ladouceur VB, Benson LN, Colan SD, Godown J, Henderson HT, Ingles J, Jeewa A, Jefferies JL, Lal AK, Mathew J, Jean-St-Michel E, Michels M, Nakano SJ, Olivotto I, Parent JJ, Pereira AC, Semsarian C, Whitehill RD, Wittekind SG, Russell MW, Conway J, Richmond ME, Villa C, Weintraub RG, Rossano JW, Kantor PF, Ho CY, Mital S. A Validated Model for Sudden Cardiac Death Risk Prediction in Pediatric Hypertrophic Cardiomyopathy. Circulation 2020 Jul 21; 142(3):217-229. [PubMed]
  • Mawad W, Mertens L, Pagano JJ, Riesenkampff E, Reichert MJE, Mital S, Kantor PF, Greenberg M, Liu P, Nathan PC, Grosse-Wortmann L. Effect of anthracycline therapy on myocardial function and markers of fibrotic remodelling in childhood cancer survivors. Eur Heart J Cardiovasc Imaging 2020 Jun 14;jeaa093. [PubMed]
  • Van Driest SL, Sleeper LA, Gelb BD, Morris SA, Dietz HC, Forbus GA, Goldmuntz E, Hoskoppal A, James J, Lee TM, Levine JC, Li JS, Loeys BL, Markham LW, Meester JAN, Mital S, Mosley JD, Olson AK, Renard M, Shaffer CM, Sharkey A, Young L, Lacro RV, Roden DM. Variants in ADRB1 and CYP2C9: Association with Response to Atenolol and Losartan in Marfan Syndrome. J Pediatr 2020 Jul; 222:213-220.e5. [PubMed]
  • Miao Y, Tian L, Martin M, Paige SL, Galdos FX, Li J, Klein A, Zhang H, Ma N, Wei Y, Stewart M, Lee S, Moonen JR, Zhang B, Grossfeld P, Mital S, Chitayat D, Wu JC, Rabinovitch M, Nelson TJ, Nie S, Wu SM, Gu M. Intrinsic Endocardial Defects Contribute to Hypoplastic Left Heart Syndrome. Cell Stem Cell 2020 Oct 1; 27(4):574-589.e8. [PubMed]
  • Min S, Kinnear C, D’Alessandro LCA, Bouwmeester J, Yao R, Chiasson D, Keeley F, Mital S. Genetic Diagnosis and the Severity of Cardiovascular Phenotype in Patients with Elastin Arteriopathy. Circ Genom Precis Med 2020 Sep 22. [PubMed]
  • Lesurf R, Said A, Akinrinade O, Breckpot O, Delfosse K, Liu T, Yao R, McKenna F, Noche RR, Oliveros W, Mattioli K, Miron A, Yang Q, Meng G, SengYue MC, Sung WWL, Thiruvahindrapuram B, Genomics England Research Consortium, Lougheed J, Oechslin E, Bergin L, Smythe J, Mondal T, Melé M, Maass PH, Ellis J, Scherer SW, Mital S. Whole genome sequencing delineates regulatory and novel genic variants in childhood cardiomyopathy. medRxiv 2020 Oct 12. [Full Text]
  • Ommen SR, Mital S, Burke MA, Day SM, Deswal A, Elliott P, Evanovich LL, Hung J, Joglar JA, Kantor P, Kimmelstiel C, Kittleson M, Link MS, Maron MS, Martinez MW, Miyake CY, Schaff HV, Semsarian C, Sorajja P. 2020 AHA/ACC Guideline for the Diagnosis and Treatment of Patients With Hypertrophic Cardiomyopathy: A Report of the American College of Cardiology/American Heart Association Joint Committee on Clinical Practice Guidelines. Circulation 2020 Nov 20. [PubMed]
  • Chaix M*, Parmar N*, Kinnear C, Lafreniere-Roula M, Akinrinade O, Yao R, Miron A, Lam E, Meng G, Christie A, Manickaraj AK, Marjerrison S, Dillenburg R, Bassal M, Lougheed J, Zelcer S, Rosenberg H, Hodgson D, Sender L, Kantor P, Manlhiot C, Ellis J, Mertens L, Nathan PC, Mital S. Machine Learning Identifies Clinical and Genetic Factors Associated with Anthracycline Cardiotoxicity in Pediatric Cancer Survivors. JACC Cardiooncology. 2020: 2(5): 690-706. [PubMed]
  • Min S, Papaz T, Lambert AN, Allen U, Birk P, Blydt-Hansen T, Foster BJ, Grasemann BJ, Hamiwka L, Litalien C, Ng V, Berka N, Campbell P, Claude D, Saw CL, Tinckham K, Urschel S, Van Driest SL, Parekh R, Mital S. An integrated clinical and genetic prediction model for tacrolimus levels in pediatric solid organ transplant recipients. Transplantation 2020; doi: 10.1097/TP.0000000000003700.[PubMed]
  • Gould R, Aziz H, Woods C, Sparks E, Preuss C, Wunnemann F, Bjeda D, Moats C, McClymont S, Rose R, Sobreira N, Ling H, MacCarrick G, Kumar AA, Luyckx I, Cannaerts E, Verstraeten A, Bjork H, Lehsau A-C, Jaskula-Ranga V, Lauridsen H, Shah A, Bennett C, Ellinor P, Lin H, Isselbacher E, Lino Cardenas C, Butcher J, Hughes GC, Lindsay M, Mertens L, Franco-Cereceda A, Verhagen J, Wessels M, Mohamed S, Eriksson P, Mital S, van Laer L, Loeys B, Andelfinger G, McCallion A, Dietz H. ROBO4 Mutations Predispose Individuals to Bicuspid Aortic Valve and Thoracic Aortic Aneurysm. Nat Genet 2019 Jan; 51 (1): 42-50 [PubMed]
  • Kinnear C, Haranal M, Shannon P, Jaeggi E, Chitayat D, Mital S. Abnormal fetal cerebrovascular development in hypoplastic left heart syndrome. Prenatal Diagnosis 2019 Jan; 39(1): 38-44 [PubMed]
  • Lafreniere-Roula M, Bolkier Y, Zahavich L, Mathew J, George K, Wilson J, Stephenson EA, Benson LN, Manlhiot CM, Mital S. Family screening for hypertrophic cardiomyopathy: Is it time to change practical guidelines? Eur Heart J 2019 Jun 6. [PubMed]
  • Mital S, Ommen S. To Screen or Not to Screen, That Is the Question. Circulation 2019 Jul 16;140(3):193-195. [PubMed]
  • Papaz T, Liston E, Zahavich L, Stavropoulos DJ, Jobling RK, Kim RH, Reuter M, Miron A, Oechslin E, Mondal T, Bergin L, Smythe JF, Altamirano-Diaz L, Lougheed J, Yao R, Akinrinade O, Breckpot J, Mital S. Return of genetic and genomic research findings: experience of a pediatric biorepository. BMC Med Genomics 2019 Nov 27;12(1):173. [PubMed]
  • Hildebrandt MR, Reuter MS, Wei W, Tayebi N, Liu J, Sharmin S, Mulder J, Lesperance LS, Brauer PM, Mok RSF, Kinnear C, Piekna A, Romm A, Howe J, Pasceri P, Meng G, Rozycki M, Rodrigues DC, Martinez EC, Szego MJ, Zúñiga-Pflücker JC, Anderson MK, Prescott SA, Rosenblum ND, Kamath BM, Mital S, Scherer SW, Ellis J. Precision Health Resource of Control iPSC Lines for Versatile Multilineage Differentiation. Stem Cell Reports 2019 Dec 10;13(6):1126-1141. [PubMed]
  • Slieker MG, Fackoury C, Slorach C, Hui W, Friedberg MK, Fan CS, Manlhiot C, Dillenburg R, Kantor P, Mital S, Liu P, Nathan PC, Mertens L. Echocardiographic Assessment of Cardiac Function in Pediatric Survivors of Anthracycline-Treated Childhood Cancer. Circ Cardiovasc Imaging 2019 Dec;12(12):e008869. [PubMed]
  • Ryan TD, Border WL, Baker-Smith C, Barac A, Bock MJ, Canobbio MM, Choueiter NF, Chowdhury D, Gambetta KE, Glickstein JS, Kondapalli L, Mital S, Peiris V, Schiff RJ, Spicer RL, Towbin JA, Chen MH. The landscape of cardiovascular care in pediatric cancer patients and survivors: a survey by the ACC Pediatric Cardio-Oncology Work Group. Cardiooncology 2019 Oct 23;5:16. [PubMed]
  • Mathew J, Zahavich L, Wilson J, George K, Benson L, Bowdin S, Mital S. Utility of Genetics for Risk Stratification in Pediatric Hypertrophic Cardiomyopathy. Clinical Genetics 2018 Feb;93:310-319 [PubMed] [Full Text]
  • Chen CK, Manlhiot C, Mital S, Schwartz SM, Van Arsdell GS, Caldarone C, McCrindle BW, Dipchand AI. Pre-listing predictions of early post-operative survival in infant heart transplantation using classification and regression tree (CART) analysis. Pediatrc Transpl 2018 Mar;22(2) [PubMed] [Full Text]
  • Newburger, JW, Sleeper LA, Gaynor JW, Hollenbeck-Pringle D, Frommelt PC, Li J, Mahle WT, Williams IA, Atz AM, Burns KM, Chen S, Cnota J, Dunbar-Masterson C, Ghanayem NS, Goldberg CS, Jacobs JP, Lewis AB, Mital S, Pizarro C, Eckhauser A, Stark p, Ohye RG, for the Pediatric Heart Network Investigators. Transplant-Free Survival and Interventions at 6 Years in the Single Ventricle Reconstruction Trial. Circulation  2018 May 22;137(21):2246-2253 [PubMed] [Full Text]
  • Pierpont ME, Brueckner M, Chung WK, Garg V, Lacro RV, McGuire AL, Mital S, Priest JR, Pu WT, Roberts A, Ware SM, Gelb BD, Russell MW. Genetic Basis for Congenital Heart Disease: Revisited. American Heart Association Scientific Statement. Circulation 2018; 138 (21): e653-e711 [PubMed] [Full Text]
  • Min S, Papaz T, Lafreniere-Roula M, Nalli N, Grasemann H, Schwartz SM, Kamath BM, Ng V, Parekh RS, Manlhiot C, Mital S. A Randomized Clinical Trial of Age and Genotype-guided Tacrolimus Dosing After Pediatric Solid Organ Transplantation. Pediatric Transplant 2018 Nov; 22(7):e13285 [PubMed] [Full Text]
  • Zahavich L, Tarnopolsky M, Yao R, Mital S. A novel association of a de novo CALM2 mutation with long QT syndrome and hypertrophic cardiomyopathy. Circ Genomics Precision Med 2018 Oct, 11(10) :e002255 [PubMed] [Full Text]
  • Gould R, Aziz H, Woods C, Sparks E, Preuss C, Wunnemann F, Bjeda D, Moats C, McClymont S, Rose R, Sobreira N, Ling H, MacCarrick G, Kumar AA, Luyckx I, Cannaerts E, Verstraeten A, Bjork H, Lehsau A-C, Jaskula-Ranga V, Lauridsen H, Shah A, Bennett C, Ellinor P, Lin H, Isselbacher E, Lino Cardenas C, Butcher J, Hughes GC, Lindsay M, Mertens L, Franco-Cereceda A, Verhagen J, Wessels M, Mohamed S, Eriksson P, Mital S, van Laer L, Loeys B, Andelfinger G, McCallion A, Dietz H. ROBO4 Mutations Predispose Individuals to Bicuspid Aortic Valve and Thoracic Aortic Aneurysm. Nat Genet 2019 Jan; 51 (1): 42-50 [PubMed] [Full Text]
  • Papaz T, Allen U, Blydt-Hansen T, Birk P, Min S, Hamiwka L, Phan V, Schechter-Finkelstein T, Wall D, Urschel S, Foster BJ, Mital S. Paediatric Outcomes in Transplant: PersOnaliSing Immunosuppression To ImproVe Efficacy (POSITIVE Study): The unique collaboration and design of a national transplant precision medicine program. Transplantation Direct 2018 Nov 27; 4 (12) e410 [PubMed] [Full Text]
  • Gillis E, Kumar AA, Luyckx I, Preuss C, Cannaerts E, van de Beek G, Wieschendorf B, Alaerts M, Bolar N, Vandeweyer G, et. al. Candidate Gene Resequencing in a Large Bicuspid Aortic Valve-Associated Thoracic Aortic Aneurysm Cohort: SMAD6 as an Important Contributor. Frontiers Physiology. 2017 Jun 13;8:400. doi: 10.3389/fphys.2017.00400. eCollection 2017.  [Pubmed] [Full Text]
  • Zahavich L, Bowdin S, Mital S. Use of Clinical Exome Sequencing in Isolated Congenital Heart Disease. Circulation Cardiovascular Genetics. 2017 Jun;10(3). pii: e001581. doi: 10.1161/CIRCGENETICS.116.001581. [Pubmed]
  • Ouellette AC, Mathew J, Manickaraj AK, Manase G, Zahavich L, Wilson J, George K, Benson L, Bowdin S, Mital S. Clinical Genetic Testing in Pediatric Cardiomyopathy: Is Bigger Better? Clinical Genetics. 2017 Mar 30. doi: 10.1111/cge.13024. [Pubmed]
  • Fridman MD, Mital S. Perspective on precision medicine in paediatric heart failure. Clinical Science (London) 2017 Mar 1;131(6):439-448. [Pubmed] [Full Text]
  • Canobbio MM, Warnes CA, Aboulhosn J, Connolly HM, Khanna A, Koos BJ, Mital S, Rose C, Silversides C, Stout K, et al, Management of Pregnancy in Patients With Complex Congenital Heart Disease: A Scientific Statement for Healthcare Professionals From the American Heart Association. Circulation 2017 Feb 21;135(8):e50-e87. [Pubmed] [Full Text]
  • Mital S, Musunuru K, Garg V, Russell MW, Lanfear DE, Gupta RM, Hickey KT, Ackerman MJ, Perez MV, Roden DM, et al. Enhancing Literacy in Cardiovascular Genetics: A Scientific Statement From the American Heart Association. Circulation Cardiovascular Genetics 2016;9(5):448-467.. [Pubmed] [Full Text]
  • Sifrim A, Hitz MP, Wilsdon A, Breckpot J, Turki SH, Thienpont B, McRae J, Fitzgerald TW, Singh T, Swaminathan GJ, et al. Distinct genetic architectures for syndromic and nonsyndromic congenital heart defects identified by exome sequencing. Nature Genetics 2016 ;48(9):1060-5. [Pubmed]
  • Patel P, Kuzmanov U, Mital S. Avoiding false discovery in biomarker research. BMC Biochemistry 2016;17(1):17. [Pubmed] [Full Text]
  • Al Teneiji A, Siriwardena K, George K, Mital S, Mercimek-Mahmutoglu S. Progressive Cerebellar Atrophy and a Novel Homozygous Pathogenic DNAJC19 Variant as a Cause of Dilated Cardiomyopathy Ataxia Syndrome. Pediatric Neurology 2016; pii: S0887-8994(15)30207-1. [Pubmed]
  • Priest JR, Osoegawa K, Mohammed N, Nanda V, Kundu R, Schultz K, Lammer EJ, Girirajan S, Scheetz T, Waggott D et al. De Novo and Rare Variants at Multiple Loci Support the Oligogenic Origins of Atrioventricular Septal Heart Defects. PLoS Genetics 2016, 12(4):e1005963. [Pubmed] [Full Text]
  • Shah SH, Arnett D, Houser SR, Ginsburg GS, MacRae C, Mital S, Loscalzo J, Hall JL. Opportunities for the Cardiovascular Community in the Precision Medicine Initiative. Circulation 2016,133(2):226-31. [Pubmed] [Full Text]
  • D’Alessandro LC, Al Turki S, Manickaraj AK, Manase D, Mulder BJ, Bergin L, Rosenberg HC, Mondal T, Gordon E, Lougheed J et al: Exome sequencing identifies rare variants in multiple genes in atrioventricular septal defect. Genetics in medicine 2016, 18;189–198. [Pubmed] [Full Text]
  • Reddy S, Fung A, Manlhiot C, Tierney ES, Chung WK, Blume E, Kaufman BD, Goldmuntz E, Colan S, Mital S. Adrenergic receptor genotype influences heart failure severity and β-blocker response in children with dilated cardiomyopathy. Pediatric Research 2015, 77(2):363-9.  [Pubmed] [Full Text]
  • Khattak S, Brimble E, Zhang W, Zaslavsky K, Strong E, Ross PJ, Hendry J, Mital S, Salter MW, Osborne LR et al: Human induced pluripotent stem cell derived neurons as a model for Williams-Beuren syndrome. Molecular brain 2015, 8(1):77. [Pubmed] [Full Text]
  • Homsy J, Zaidi S, Shen Y, Ware JS, Samocha KE, Karczewski KJ, DePalma SR, McKean D, Wakimoto H, Gorham J et al: De novo mutations in congenital heart disease with neurodevelopmental and other congenital anomalies. Science (New York, NY) 2015, 350(6265):1262-1266. [Pubmed]
  • Burchill LJ, Redington AN, Silversides CK, Ross HJ, Jimenez-Juan L, Mital S, Oechslin EN, Dragulescu A, Slorach C, Mertens L et al: Renin-angiotensin-aldosterone system genotype and serum BNP in a contemporary cohort of adults late after Fontan palliation. International journal of cardiology 2015, 197:209-215. [Pubmed]
  • Bhatt AB, Foster E, Kuehl K, Alpert J, Brabeck S, Crumb S, Davidson WR, Jr., Earing MG, Ghoshhajra BB, Karamlou T et al: Congenital heart disease in the older adult: a scientific statement from the American Heart Association. Circulation 2015, 131(21):1884-1931. [Pubmed] [Full Text]
  • Newburger JW, Sleeper LA, Frommelt PC, Pearson GD, Mahle WT, Chen S, Dunbar-Masterson C, Mital S, Williams IA, Ghanayem NS et al: Transplantation-free survival and interventions at 3 years in the single ventricle reconstruction trial. Circulation 2014, 129(20):2013-2020. [Pubmed] [Full Text]
  • Manase D, D’Alessandro LC, Manickaraj AK, Al Turki S, Hurles ME, Mital S: High throughput exome coverage of clinically relevant cardiac genes. BMC medical genomics 2014, 7:67. [Pubmed] [Full Text]
  • Jeewa A, Manlhiot C, Kantor PF, Mital S, McCrindle BW, Dipchand AI: Risk factors for mortality or delisting of patients from the pediatric heart transplant waiting list. The Journal of thoracic and cardiovascular surgery 2014, 147(1):462-468. [Pubmed]
  • Gaynor JW, Kim DS, Arrington CB, Atz AM, Bellinger DC, Burt AA, Ghanayem NS, Jacobs JP, Lee TM, Lewis AB et al: Validation of association of the apolipoprotein E epsilon2 allele with neurodevelopmental dysfunction after cardiac surgery in neonates and infants. The Journal of thoracic and cardiovascular surgery 2014, 148(6):2560-2566. [Pubmed] [Full Text]
  • Fahed AC, Roberts AE, Mital S, Lakdawala NK: Heart failure in congenital heart disease: a confluence of acquired and congenital. Heart failure clinics 2014, 10(1):219-227. [Pubmed] [Full Text]
  • Burns KM, Byrne BJ, Gelb BD, Kuhn B, Leinwand LA, Mital S, Pearson GD, Rodefeld M, Rossano JW, Stauffer BL et al: New mechanistic and therapeutic targets for pediatric heart failure: report from a National Heart, Lung, and Blood Institute working group. Circulation 2014, 130(1):79-86. [Pubmed] [Full Text]
  • Al Turki S, Manickaraj AK, Mercer CL, Gerety SS, Hitz MP, Lindsay S, D’Alessandro LC, Swaminathan GJ, Bentham J, Arndt AK et al: Rare variants in NR2F2 cause congenital heart defects in humans. American journal of human genetics 2014, 94(4):574-585. [Pubmed] [Full Text]
  • Patel P, Mital S: Stem cells in pediatric cardiology. European journal of pediatrics 2013, 172(10):1287-1292. [Pubmed] [Full Text]
  • Molina KM, Shrader P, Colan SD, Mital S, Margossian R, Sleeper LA, Shirali G, Barker P, Canter CE, Altmann K et al: Predictors of disease progression in pediatric dilated cardiomyopathy. Circulation Heart failure 2013, 6(6):1214-1222. [Pubmed] [Full Text]
  • Kinnear C, Chang WY, Khattak S, Hinek A, Thompson T, de Carvalho Rodrigues D, Kennedy K, Mahmut N, Pasceri P, Stanford WL et al: Modeling and rescue of the vascular phenotype of Williams-Beuren syndrome in patient induced pluripotent stem cells. Stem cells translational medicine 2013, 2(1):2-15. [Pubmed] [Full Text]
  • Gaber N, Gagliardi M, Patel P, Kinnear C, Zhang C, Chitayat D, Shannon P, Jaeggi E, Tabori U, Keller G et al: Fetal reprogramming and senescence in hypoplastic left heart syndrome and in human pluripotent stem cells during cardiac differentiation. The American journal of pathology 2013, 183(3):720-734. [Pubmed] [Full Text]
  • Fung A, Manlhiot C, Naik S, Rosenberg H, Smythe J, Lougheed J, Mondal T, Chitayat D, McCrindle BW, Mital S: Impact of prenatal risk factors on congenital heart disease in the current era. Journal of the American Heart Association 2013, 2(3):e000064. [Pubmed] [Full Text]
  • Cordell HJ, Topf A, Mamasoula C, Postma AV, Bentham J, Zelenika D, Heath S, Blue G, Cosgrove C, Granados Riveron J et al: Genome-wide association study identifies loci on 12q24 and 13q32 associated with tetralogy of Fallot. Human molecular genetics 2013, 22(7):1473-1481. [Pubmed] [Full Text]
  • Cordell HJ, Bentham J, Topf A, Zelenika D, Heath S, Mamasoula C, Cosgrove C, Blue G, Granados-Riveron J, Setchfield K et al: Genome-wide association study of multiple congenital heart disease phenotypes identifies a susceptibility locus for atrial septal defect at chromosome 4p16. Nature genetics 2013, 45(7):822-824. [Pubmed] [Full Text]
  • Buske OJ, Manickaraj A, Mital S, Ray PN, Brudno M: Identification of deleterious synonymous variants in human genomes. Bioinformatics (Oxford, England) 2013, 29(15):1843-1850. [Pubmed] [Full Text]
  • Binesh Marvasti T, D’Alessandro LC, Manase D, Papaz T, Mital S: Personalized medicine in the care of the child with congenital heart disease: discovery to application. Congenital heart disease 2013, 8(3):266-269. [Pubmed] [Full Text]
  • Yoon G, Soman T, Wilson J, George K, Mital S, Dipchand AI, McCabe J, Logan W, Kantor P: Cardiac transplantation in Friedreich ataxia. Journal of child neurology 2012, 27(9):1193-1196. [Pubmed] [Full Text]
  • Papaz T, Safi M, Manickaraj AK, Ogaki C, Breaton Kyryliuk J, Burrill L, Dodge C, Chant-Gambacort C, Walter LL, Rosenberg H et al: Factors influencing participation in a population-based biorepository for childhood heart disease. Pediatrics 2012, 130(5):e1198-1205. [Pubmed] [Full Text]
  • Newburger JW, Sleeper LA, Bellinger DC, Goldberg CS, Tabbutt S, Lu M, Mussatto KA, Williams IA, Gustafson KE, Mital S et al: Early developmental outcome in children with hypoplastic left heart syndrome and related anomalies: the single ventricle reconstruction trial. Circulation 2012, 125(17):2081-2091. [Pubmed] [Full Text]
  • Manickaraj AK, Mital S: Personalized medicine in pediatric cardiology: do little changes make a big difference? Current opinion in pediatrics 2012, 24(5):584-591.[Pubmed]
  • Jeewa A, Manickaraj AK, Mertens L, Manlhiot C, Kinnear C, Mondal T, Smythe J, Rosenberg H, Lougheed J, McCrindle BW et al: Genetic determinants of right-ventricular remodeling after tetralogy of Fallot repair. Pediatric research 2012, 72(4):407-413. [Pubmed] [Full Text]
  • Farra N, Manickaraj AK, Ellis J, Mital S: Personalized Medicine in the Genomics Era: highlights from an international symposium on childhood heart disease. Future cardiology 2012, 8(2):157-160. [Pubmed]
  • Alkon J, Friedberg MK, Manlhiot C, Manickaraj AK, Kinnear C, McCrindle BW, Benson LN, Addonizio LJ, Colan SD, Mital S: Genetic variations in hypoxia response genes influence hypertrophic cardiomyopathy phenotype. Pediatric research 2012, 72(6):583-592. [Pubmed] [Full Text]
  • Ofori-Amanfo G, Hsu D, Lamour JM, Mital S, O’Byrne ML, Smerling AJ, Chen JM, Mosca R, Addonizio LJ: Heart transplantation in children with markedly elevated pulmonary vascular resistance: impact of right ventricular failure on outcome. The Journal of heart and lung transplantation 2011, 30(6):659-666. [Pubmed]
  • Mital S, Chung WK, Colan SD, Sleeper LA, Manlhiot C, Arrington CB, Cnota JF, Graham EM, Mitchell ME, Goldmuntz E et al: Renin-angiotensin-aldosterone genotype influences ventricular remodeling in infants with single ventricle. Circulation 2011, 123(21):2353-2362. [Pubmed] [Full Text]
  • Mital S: Personalizing medicine for the child with heart disease: a path forward. Journal of cardiovascular pharmacology 2011, 58(1):1-3. [Pubmed]
  • Lai WW, Vetter VL, Richmond M, Li JS, Saul JP, Mital S, Colan SD, Newburger JW, Sleeper LA, McCrindle BW et al: Clinical research careers: reports from a NHLBI pediatric heart network clinical research skills development conference. American heart journal 2011, 161(1):13-67. [Pubmed] [Full Text]
  • Kantor PF, Rusconi P, Lipshultz S, Mital S, Wilkinson JD, Burch M: Current applications and Future Needs for Biomarkers in Pediatric Cardiomyopathy and Heart Failure: Summary From The Second International Conference On Pediatric Cardiomyopathy. Progress in pediatric cardiology 2011, 32(1):11-14. [Pubmed] [Full Text]
  • Gijsen V, Mital S, van Schaik RH, Soldin OP, Soldin SJ, van der Heiden IP, Nulman I, Koren G, de Wildt SN: Age and CYP3A5 genotype affect tacrolimus dosing requirements after transplant in pediatric heart recipients. The Journal of heart and lung transplantation 2011, 30(12):1352-1359. [Pubmed] [Full Text]
  • Davies RR, Russo MJ, Hong KN, Mital S, Mosca RS, Quaegebeur JM, Chen JM: Increased short- and long-term mortality at low-volume pediatric heart transplant centers: should minimum standards be set? Retrospective data analysis. Annals of surgery 2011, 253(2):393-401. [Pubmed] [Full Text]
  • Burchill L, Greenway S, Silversides CK, Mital S: Genetic counseling in the adult with congenital heart disease: what is the role? Current cardiology reports 2011, 13(4):347-355. [Pubmed]
  • Williams RV, Ravishankar C, Zak V, Evans F, Atz AM, Border WL, Levine J, Li JS, Mahony L, Mital S et al: Birth weight and prematurity in infants with single ventricle physiology: pediatric heart network infant single ventricle trial screened population. Congenital heart disease 2010, 5(2):96-103. [Pubmed] [Full Text]
  • Stevens KN, Hakonarson H, Kim CE, Doevendans PA, Koeleman BP, Mital S, Raue J, Glessner JT, Coles JG, Moreno V et al: Common variation in ISL1 confers genetic susceptibility for human congenital heart disease. PloS one 2010, 5(5):e10855. [Pubmed] [Full Text]
  • Silversides CK, Marelli A, Beauchesne L, Dore A, Kiess M, Salehian O, Bradley T, Colman J, Connelly M, Harris L et al: Canadian Cardiovascular Society 2009 Consensus Conference on the management of adults with congenital heart disease: executive summary. The Canadian journal of cardiology 2010, 26(3):143-150. [Pubmed] [Full Text]
  • Ohye RG, Sleeper LA, Mahony L, Newburger JW, Pearson GD, Lu M, Goldberg CS, Tabbutt S, Frommelt PC, Ghanayem NS et al: Comparison of shunt types in the Norwood procedure for single-ventricle lesions. The New England journal of medicine 2010, 362(21):1980-1992. [Pubmed] [Full Text]
  • Minich LL, Atz AM, Colan SD, Sleeper LA, Mital S, Jaggers J, Margossian R, Prakash A, Li JS, Cohen MS et al: Partial and transitional atrioventricular septal defect outcomes. The Annals of thoracic surgery 2010, 89(2):530-536. [Pubmed] [Full Text]
  • Marelli A, Beauchesne L, Mital S, Therrien J, Silversides CK: Canadian Cardiovascular Society 2009 Consensus Conference on the management of adults with congenital heart disease: introduction. The Canadian journal of cardiology 2010, 26(3):e65-69. [Pubmed] [Full Text]
  • Hsu DT, Zak V, Mahony L, Sleeper LA, Atz AM, Levine JC, Barker PC, Ravishankar C, McCrindle BW, Williams RV et al: Enalapril in infants with single ventricle: results of a multicenter randomized trial. Circulation 2010, 122(4):333-340. [Pubmed] [Full Text]
  • Cadeiras M, Shahzad K, John MM, Gruber D, Bayern M, Auerbach S, Sinha A, Latif F, Unniachan S, Memon S et al: Relationship between a validated molecular cardiac transplant rejection classifier and routine organ function parameters. Clinical transplantation 2010, 24(3):321-327. [Pubmed]
  • Hsu DT, Mital S, Ravishankar C, Margossian R, Li JS, Sleeper LA, Williams RV, Levine JC, McCrindle BW, Atz AM et al: Rationale and design of a trial of angiotensin-converting enzyme inhibition in infants with single ventricle. American heart journal 2009, 157(1):37-45. [Pubmed] [Full Text]
  • Auerbach SR, Manlhiot C, Reddy S, Kinnear C, Richmond ME, Gruber D, McCrindle BW, Deng L, Chen JM, Addonizio LJ et al: Recipient genotype is a predictor of allograft cytokine expression and outcomes after pediatric cardiac transplantation. Journal of the American College of Cardiology 2009, 53(20):1909-1917. [Pubmed] [Full Text]
  • Paridon SM, Mitchell PD, Colan SD, Williams RV, Blaufox A, Li JS, Margossian R, Mital S, Russell J, Rhodes J: A cross-sectional study of exercise performance during the first 2 decades of life after the Fontan operation. Journal of the American College of Cardiology 2008, 52(2):99-107. [Pubmed] [Full Text]
  • Osorio JC, Cheema FH, Martens TP, Mahmut N, Kinnear C, Gonzalez AM, Bonney W, Homma S, Liao JK, Mital S: Simvastatin reverses cardiac hypertrophy caused by disruption of the bradykinin 2 receptor. Canadian journal of physiology and pharmacology 2008, 86(9):633-642. [Pubmed] [Full Text]
  • Kaufman BD, Desai M, Reddy S, Osorio JC, Chen JM, Mosca RS, Ferrante AW, Mital S: Genomic profiling of left and right ventricular hypertrophy in congenital heart disease. Journal of cardiac failure 2008, 14(9):760-767. [Pubmed]
  • Vogt KN, Manlhiot C, Van Arsdell G, Russell JL, Mital S, McCrindle BW: Somatic growth in children with single ventricle physiology impact of physiologic state. Journal of the American College of Cardiology 2007, 50(19):1876-1883. [Pubmed] [Full Text]
  • Mital S: Value of surveillance biopsy in pediatric heart transplantation. Pediatric transplantation 2007, 11(3):233-235. [Pubmed]
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