Li lab members

Dr. Yun Li leaning against a railing, smiling

Dr. Yun Li


Dr. Yun Li is a neurobiologist interested in understanding human brain development and diseases. She attended graduate school at the University of Texas Southwestern Medical Center. Her PhD work, conducted in the lab of Luis Parada, focused on using genetically engineered mouse models to study psychiatric disorders like depression and anxiety, as well as neurodegeneration such as Alzheimer’s and Huntington’s diseases.

As a postdoctoral fellow, Yun worked in the lab of Rudolf Jaenisch at The Whitehead Institute and MIT. She used human pluripotent stem cells to create “disease-in-a-dish” models of human brain disorders such as Rett Syndrome and microcephaly. Her work also combined brain organoid with CRISPR genome editing, to create 3-dimensional models of human brain development and diseases.

Dr. Yun Li is currently a Scientist in the Development and Stem Cell Biology Program at The Hospital for Sick Children, and an Assistant Professor in the Department of Molecular Genetics at the University of Toronto. She is also a Medicine by Design Investigator, and received Young Investigator Award recognitions from the Stem Cell Network, Brain Canada, Epilepsy Canada, Brain & Behavior Research Foundation, and Simons Foundation.

Alex Ng
Aditi Aggarwal