Other ongoing clinical studies
| Study title | Study objective |
|---|---|
| Quantification of ventricular function in hearts with pressure and/or volume overload and their acute response to cardiac interventions | Evaluate the end-systolic and end-diastolic pressure-volume relationship as well as stroke work, and elastance and diastolic myocardial stiffness as a method of quantifying ventricular function |
| Ultrafast Ultrasound Imaging: Application in Paediatric Cardiology | Aim 1: We will validate UFUS non-invasive methods against gold-standard invasive pressure measurements and tissue characterization by cardiac MRI. Aim 2: We will define maturational changes in UFUS parameters during normal growth in comparison to changes in patients with suspected LV or RV DD. Aim 3: We will define myocardial perfusion and myocardial stiffness in 2 specific congenital heart defect populations (transposition of great arteries and hypoplastic left heart syndrome) before and after surgery. |
| Brain perfusion in congenital heart disease: Ultrafast Ultrasound Imaging & MRI (cola. Birgit Erlt Wagner) | Establish reference values of cerebral blood flow (CBF) and cerebral resistivity indexes (RI) in healthy newborns and congenital heart defects (TGA and HLHS) for both Ultrafast Ultrasound and Magnetic Resonance perfusion imaging |
| Validation of electromechanical delay assessment by ultrafast ultrasound imaging with electrophysiology studies | Compare the myocardium mechanical activation mapping as obtained by electromechanical wave imaging (ultrafast imaging) with the gold standard of electrical activation during an invasive electrophysiology study. |
