The SPARC lentiviral core facility provides production of small-scale lentiviral stocks containing shRNA or cDNA for your gene(s) of interest, as well as lentiviral concentration, titrations and transductions. To ensure the compliance with biosafety containment required for lentiviral-based research, SPARC uses the Horizon Discovery TransLenti™ Viral GPIZ Packaging System. The facility will construct individual lentiviral constructs from template cDNA in our set of lentiviral vectors or shRNA from our extensive on-site pGIPZ human and mouse shRNA libraries.