Longitudinal data subject to irregular observation

2023

Pullenayegum EM (PA), Birken C, Maguire J, The TARTGet Kids! Collaboration. Causal Inference with Longitudinal Data Subject to Irregular Assessment Times. Stat Med. 2023 Jun 30;42(14):2361-2393. doi: 10.1002/sim.9727. Epub 2023 Apr 13. PMID: 37054723.

2022

Pullenayegum EM, Scharfstein DO. Randomized Trials with Repeatedly Measured Outcomes: Handling Irregular and Potentially Informative Assessment Times. Epidemiologic Reviews 2022 Dec 21;44(1):121-137. doi: 10.1093/epirev/mxac010 (online ahead of print). PMID: 36259969
Golchi S, Willard JJ, Pullenayegum EM (CA), Bassani DG, Pell LG, Thorlund K, Roth DE. A Bayesian adaptive design for clinical trials of rare efficacy outcomes with multiple definitions. Clin Trials. 2022 Dec;19(6):613-622. doi: 10.1177/17407745221118366. PMID: 36408565
Aghababaei Jazi O, Pullenayegum E., Variable selection in semiparametric regression models for longitudinal data with informative observation times. Stat Med. 2022 Jul 40; 41(17): 3281-3298. doi: 10.1002/sim.9417. PMID: 35468658

2021

Lokku A*, Birken CS, Maguire JL, Pullenayegum EM; TARGet Kids! Collaboration. Quantifying the extent of visit irregularity in longitudinal data. Int J Biostat. 2021 Aug 16. doi: 10.1515/ijb-2020-0144. Online ahead of print. PMID: 34392639https://pubmed.ncbi.nlm.nih.gov/34392639/
Pullenayegum EM, Birken C, Maguire J; TARGet Kids! Collaboration, Clustered longitudinal data subject to irregular observation. Stat Methods Med Res.2021 Apr;30(4):1081-1100. doi: 10.1177/0962280220986193. Epub 2021 Jan 29. PMID: 33509042

2020

Lokku A*, Lim LS, Birken CS, Pullenayegum EM; TARGet Kids! Collaboration. Summarizing the extent of visit irregularity in longitudinal data. BMC Med Res Methodol. 2020 May 29;20(1):135. doi: 10.1186/s12874-020-01023-w. PMID: 32471357
Liu K*, Saarela O, Feldman BM, Pullenayegum E. Estimation of causal effects with repeatedly measured outcomes in a Bayesian framework. Stat Methods Med Res. 2020 Sep;29(9):2507-2519. doi: 10.1177/0962280219900362. Epub 2020 Jan 29. PMID: 31994451

Lim LSH, Pullenayegum EM, Feldman BM, Lim L, Gladman DD, Silverman ED. From Childhood to Adulthood: Disease Activity Trajectories in Childhood-Onset Systemic Lupus Erythematosus. Arthritis Care & Research (Hoboken). 2018; 70(5): 750-757. doi: 10.1002/acr.23319. Epub date: March 25 2018. PubMed PMID: 28704581

2017

Lim LSH, Pullenayegum E, Lim L, Gladman D, Feldman B, Silverman E. From Childhood to Adulthood: The Trajectory of Damage in Patients With Juvenile-Onset Systemic Lupus Erythematosus. Arthritis Care Res (Hoboken). 2017 Nov;69(11):1627-1635. doi: 10.1002/acr.23199. Epub 2017 Sep 26. PMID: 28118527
Farzanfar D*, Abumuamar A, Kim J, Sirotich E, Wang Y, Pullenayegum E. Longitudinal studies that use data collected as part of usual care risk reporting biased results: a systematic review. BMC Medical Research Methodology. 2017 Sep 6; 17(1):133. doi: 10.1186/s12874-017-0418-1. PubMed PMID: 28877680

2016 and earlier

Pullenayegum EM. Multiple outputation for the analysis of longitudinal data subject to irregular observation. Statistics in Medicine. 2016; 35(11); 1800-18. Epub date: 2015 Dec 13. doi: 10.1002/sim.6829. PubMed PMID: 26661690.
Pullenayegum EM, Lim LS. Longitudinal data subject to irregular observation: A review of methods with a focus on visit processes, assumptions, and study design. Statistical Methods in Medical Research. 2016 Dec; 25(6); 2992-3014. Epub date: 2014 May 21. doi: 10.1177/0962280214536537 pii: 0962280214536537. PubMed PMID: 24855119
Pullenayegum EM, Feldman BM. Doubly robust estimation, optimally truncated inverse-intensity weighting and increment-based methods for the analysis of irregularly observed longitudinal data. Statistics in Medicine. 2013 Mar 15; 32(6):1054-72. doi:10.1002/sim.5640. Epub 2012 Oct 10. PubMed PMID: 23047604
Pullenayegum EM, Cook RJ. The analysis of treatment effects for recurring episodic conditions. Statistics in Medicine 2010 Jun30; 29(14):1539-58. PubMed PMID: 20535764
Pullenayegum EM, Lam C, Manlhiot C, Feldman BM. Fitting Marginal Structural Models: Estimating covariate-treatment associations in the re-weighted dataset can guide model fitting. Journal of Clinical Epidemiology 2008 Sep;61(9):875-81. doi: 10.1016/j.jclinepi.2007.10.024. Epub 2008 May 16
Pullenayegum E; Xi Y*, Lim L; Levin J, Feldman B, Choosing the frequency of follow-up in longitudinal studies: is more necessarily better? Research Methods in Medicine & Health Sciences
Pullenyaegum EM. Meeting the Assumptions of Inverse-Intensity Weighting for Longitudinal Data Subject to Irregular Follow-Up: Suggestions for the Design and Analysis of Clinic-Based Cohort Studies. Epidemiologic Methods (epub ahead of print)

Health Utilities

2024

Roudijk B, Jonker MF, Bailey H, Pullenayegum EM. A Direct Comparison Between Discrete Choice With Duration and Composite Time Trade-Off Methods: Do They Produce Similar Results? Value Health. 2024 Sep;27(9):1280-1288. doi: 10.1016/j.jval.2024.05.016. Epub 2024 Jun 4. PMID: 38843979.
Tsui TCO*, Chan KKW, Xie F, Pullenayegum EM. Creating a Multiply Imputed Value Set for the EQ-5D-5L in Canada: State-Level Misspecification Terms Are Needed to Characterize Parameter Uncertainty Correctly. Med Decis Making. 2024 Apr 9:272989X241241328. doi: 10.1177/0272989X241241328. Epub ahead of print.

2023

Che M*, Xie F, Thomas S, Pullenayeugm EM (SRA). Bayesian models with spatial correlation improve the precision of EQ-5D-5L value sets. Medical Decision Making (accepted April 2023).
Che M*, Pullenayegum E. Efficient designs for valuation studies that use time trade-off (TTO) tasks to map latent utilities from discrete choice experiments to the interval scale: selection of health states for TTO tasks. Medical Decision Making (in press)

2020

Shams S*, Pullenayegum E. Design and sample size considerations for valuation studies of multi-attribute utility instruments. Stat Med. 2020 Oct 15;39(23):3074-3104. doi: 10.1002/sim.8592. Epub 2020 Jul 24. PMID: 32706130
Waudby-Smith I*, Pickard AS, Xie F, Pullenayegum EM. Using Both Time Tradeoff and Discrete Choice Experiments in Valuing the EQ-5D: Impact of Model Misspecification on Value Sets. Med Decis Making. 2020 May;40(4):483-497. doi: 10.1177/0272989X20924019. Epub 2020 Jun 9. PMID: 32517541
Chan KKW, Pullenayegum EM. The Theoretical Relationship between Sample Size and Expected Predictive Precision for EQ-5D Valuation Studies: A Mathematical Exploration and Simulation Study. Medical Decision Making 2020 Apr;40(3):339-347. doi: 10.1177/0272989X20915452. PMID: 32428427

2019

Pickard AS, Law EH, Jiang R, Pullenayegum E, Shaw JW, Xie F, Oppe M, Boye KS, Chapman RH, Gong CL, Balch A, Busschbach JJV. United States Valuation of EQ-5D-5L Health States Using an International Protocol. Value Health. 2019 Aug;22(8):931-941. doi: 10.1016/j.jval.2019.02.009. Epub 2019 May 25. PMID: 31426935
Pullenayegum EM, Pickard AS, Xie F. Latent Class Models Reveal Poor Agreement between Discrete Choice and Time Tradeoff Preferences. Medical Decision Making. 2019 May; 39(4):421-436. doi: 10.1177/0272989X19841592. Epub 2019 Apr 13. PubMed PMID: 30982403
Shams S*, Pullenayegum E. Reducing Uncertainty in EQ-5D Value Sets: The Role of Spatial Correlation. Medical Decision Making. 2019 Feb; 39(2):91-99. doi: 10.1177/0272989X18821368. Epub 2019 Jan 24. PubMed PMID: 30678526

2017

Chan KKW*, Xie F, Willan AR, Pullenayegum EM. Conducting EQ-5D Valuation Studies in Resource-Constrained Countries: The Potential Use of Shrinkage Estimators to Reduce Sample Size. Medical Decision Making. 2018; 38(1): 26-33. Doi: 10.1177/0272989X17725748. Epub date: 2017 August 19. PubMed PMID: 28823185

2016

Xie F, Pullenayegum E, Pickard AS, Ramos Goñi JM, Jo MW, Igarashi A. Transforming Latent Utilities to Health Utilities: East Does Not Meet West. Health Econ. 2017 Dec;26(12):1524-1533. doi: 10.1002/hec.3444. Epub 2016 Oct 16. PMID: 27747973
Pullenayegum EM, Sunderland K*, Johnson JA, Xie F. Handling regional variation in Health State Preferences within a country. Medical Decision Making. 2017 Apr;37(3):252-261. doi: 10.1177/0272989X16651885. Epub 2016 Jul 10. PMID: 27270112
Chan KKW*, Xie F, Willan AR, Pullenayegum EM. Underestimation of Variance of Predicted Health Utilities Derived from Multi-Attribute Utility Instruments: The Use of Multiple Imputation as a Potential Solution. Medical Decision Making. 2017; 37(3); 262- 272. Epub date July 10 2016. Doi: 10.1177/0272989X16650181. PMID: 27216582
Tsiplova K*, Pullenayegum E, Cooke T, Xie F. EQ-5D-derived health utilities and minimally important differences for chronic health conditions: 2011 Commonwealth Fund Survey of Sicker Adults in Canada. Quality of Life Research. 2016 June 15; 25(12); 3009-3016. Doi: 10.1007/s11136-016-1336-0. PubMed PMID: 27307010
Xie F, Pullenayegum E, Gaebel K, Bansback N, Bryan S, Ohinmaa A, Poissant L, Johnson JA. How different are composite and traditional TTO valuations of severe EQ- 5D-5L States? Quality of Life Research. 2016 Aug; 25(8); 2101-2108. Epu 2016 Feb 13. Doi: 10.1007/s11136-016-1242-5. PubMed PMID: 26875190
Xie F, Pullenayegum E, Gaebel K, Bansback N, Bryan S, Ohinmaa A, Poissant L, Johnson JA; Canadian EQ-5D-5L Valuation Study Group. A Time Trade-off-derived Value Set of the EQ-5D-5L for Canada. Medical Care. 2016 Jan; 54(1):98-105. doi: 10.1097/MLR.0000000000000447. PubMed PMID: 26492214; PubMed PMID: 4674140

2015

Sayah FA, Bansback N, Bryan S, Ohinmaa A, Poissant L, Pullenayegum E, Xie F, Johnson JA. Determinants of time trade-off valuations for EQ-5D-5L health states: data from the Canadian EQ-5D-5L valuation study. Quality of Life Research. 2016 Jul; 25(7); 1679-1685. Epub date: 2015 Dec 10. Doi: 10.1007/s11136-015-1203-4 PubMed PMID: 26659899
Pullenayegum EM, Perampaladas K, Gaebel K, Doble B, Xie F. Between-country heterogeneity in EQ-5D-3L scoring algorithms: how much is due to differences in health state selection? European Journal of Health Economics. 2015 Nov;16(8):847-55. doi: 10.1007/s10198-014-0633-1. Epub 2014 Sep 25. PMID: 25252970
Pullenayegum EM, Chan KKW*, Xie F. Quantifying Parameter Uncertainty in EQ-5D- 3L Value Sets and Its Impact on Studies That Use the EQ-5D-3L to Measure Health Utility: A Bayesian Approach. Medical Decision Making. 2016; 36(2): 223-233. doi: 10.1177/0272989X15591966. Epub date: July 2 2015. pii: 0272989X15591966. PubMed PMID: 26139449

2014

Chan KKW*, Gupta M, Willan A, Pullenayegum EM. Underestimation of Uncertainties in Health Utilities derived from Mapping Algorithms involving Health Related Quality of Life Measures: Statistical Explanations and Potential Remedies. Medical Decision Making. 2014 Oct; 34(7):863-72. doi: 10.1177/0272989X13517750. Epub 2014 Jan 9. PubMed PMID: 24407513

2013

Xie F, Pullenayegum EM, Gaebel K, Oppe M, Krabbe PF. Eliciting preferences to the EQ-5D-5L health states: discrete choice experiment or multiprofile case of best-worst scaling? European Journal of Health Economics. 2014 Apr; 15(3); 281-288. Doi: 10.1007/s10198-013-0474-3 Epub date: Apr 4 2013. PubMed PMID: 23553075
Xie F, Gaebel K, Perampaladas K, Doble B, Pullenayegum EM. Comparing EQ-5D Valuation Studies: A Systematic Review and Methodological Reporting Checklist. Medical Decision Making. 2014 Jan; 34(1); 8-20. Doi: 10.1177/0272989X13480852. Epub date: 2013 Mar 22. PubMed PMID: 23525701
Pullenayegum EM, Xie F. Scoring the 5-Level EQ-5D: Can Latent Utilities Derived from a Discrete Choice Model Be Transformed to Health Utilities Derived from Time Tradeoff Tasks? Medical Decision Making. 2013 May; 33(4):567-78. doi: 10.1177/0272989X13475718. Epub 2013 Mar 8. PubMed PMID: 23475942

2012 and earlier

Pullenayegum EM, Wong HS*, Childs A. Generalized additive models for the analysis of EQ-5D utility data. Medical Decision Making. 2013 Feb; 33(2):244-51. doi:10.1177/0272989X12465354. Epub 2012 Nov 6. PubMed PMID: 23132902
Pullenayegum EM, Tarride JE, Xie F, O’Reilly D. Calculating Utility Decrements Associated with an Adverse Event: Marginal Tobit and CLAD Coefficients Should be Used With Caution. Medical Decision Making. 2011 Nov: 31(6):790-9 PMID: 22067429
Pullenayegum EM, Tarride J-E, Xie F, Goeree R, Gerstein H, O’Reilly D. Analysis of health utility data when some subjects attain the upper bound of 1: are Tobit and CLAD models appropriate? Value in Health. 2010 Jun-Jul; 13(4):487-94. Epub 2010 Mar 10. PubMed PMID: 20230549
Pullenayegum EM, Willan AR. Semi-parametric models for cost-effectiveness analysis: improving the efficiency of estimation from censored data. Statistics in Medicine. 2007 Jul 30;26(17):3274-99. doi: 10.1002/sim.2814 PMID: 17309112
Willan AR, Goeree R, Pullenayegum EM, McBurney C, Blackhouse G. Economic evaluation of rivastigmine in patients with Parkinson’s disease dementia. Pharmacoeconomics 2006; 24(1): 93-106 doi: 10.2165/00019053-200624010-00008 PMID: 16445306
Pinto EM, Willan AR, O’Brien BJ. Cost-effectiveness analysis for multinational clinical trials. Statistics in Medicine. 2005 Jul 15;24(13):1965-82.
doi: 10.1002/sim.2078 PMID: 15803442
Willan AR, Pinto EM. The Value of Information and Optimal Clinical Trial Design. Statistics in Medicine. 2005 Jun 30;24(12):1791-806.
doi: 10.1002/sim.2069 PMID: 15806619
Willan AR, Pinto EM, O’Brien BJ, Kaul P, Goeree R, Lynd L, Armstrong PW. Country specific cost comparisons from multinational clinical trials using empirical Bayesian shrinkage estimation: the Canadian ASSENT-3 economic analysis. Health Economics. 2005 Apr;14(4):327-38.
doi: 10.1002/hec.969 PMID: 15685652

Knowledge Translation

2018

Lim LSH, Pullenayegum EM, Feldman BM, Lim L, Gladman DD, Silverman ED. From Childhood to Adulthood: Disease Activity Trajectories in Childhood-Onset Systemic Lupus Erythematosus. Arthritis Care & Research (Hoboken). 2018 May; 70(5): 750-757. doi: 10.1002/acr.23319. Epub 2018 Mar 25 PMID: 28704581

2017

Tian SY, Silverman ED, Pullenayegum EM, Brown PE, Beyene J, Feldman BM. Comparative Effectiveness of Mycophenolate Mofetil for the Treatment of Childhood-Onset Proliferative Lupus Nephritis. Arthritis Care and Research (Hoboken). 2018 May; 69(12):1887-1894. Epub 2017 Nov 2. doi: 10.1002/acr.23215. PubMed PMID: 28182833
Lim LSH, Pullenayegum E, Lim L, Gladman D, Feldman B, Silverman E. From Childhood to Adulthood: The Trajectory of Damage in Patients With Juvenile-Onset Systemic Lupus Erythematosus. Arthritis Care Res (Hoboken). 2017 Nov;69(11):1627-1635. doi: 10.1002/acr.23199. Epub 2017 Sep 26. PMID: 28118527
Farzanfar D*, Abumuamar A, Kim J, Sirotich E, Wang Y, Pullenayegum E. Longitudinal studies that use data collected as part of usual care risk reporting biased results: a systematic review. BMC Medical Research Methodology. 2017 Sep 6; 17(1):133. doi: 10.1186/s12874-017-0418-1. PubMed PMID: 28877680.

2015 and earlier

Pullenayegum EM, Platt RW, Barwick M, Feldman BM, Offringa M, Thabane L. Knowledge translation in biostatistics: a survey of current practices, preferences, and barriers to the dissemination and uptake of new statistical methods. Statistics in Medicine. 2016 Mar; 35(6); 805-818. doi: 10.1002/sim.6633. Epub date: 2015 Aug 25. PubMed PMID: 26307183
O’Reilly DJ, Xie F, Pullenayegum EM, Gerstein HC, Greb J, Blackhouse GK, Tarride JE, Bowen J, Goeree RA. Estimation of the impact of diabetes-related complications on health utilities for patients with type 2 diabetes in Ontario, Canada. Quality of Life Research. 2011 Aug 20; (6):939-43. Epub 2011 Jan 8 PMID: 21221816.
Pullenayegum EM, Thabane L. Teaching Bayesian Statistics in a Health Research Methodology Program. Journal of Statistics Education 2009; 17(3)

Collaborations

2024

Rae S, Pullenayegum E, Ong F, Dennis CL, Hamilton J, Maguire J, Birken C. Reliability of Anthropometric Measurement of Young Children with Parent Involvement. Child Obes. 2024 Aug 22. doi: 10.1089/chi.2023.0065. Epub ahead of print. PMID: 39169843.
Motaghi S, Pullenayegum E, Morgan RL, Loeb M. The role of influenza Hemagglutination-Inhibition antibody as a vaccine mediator in children. Vaccine. 2024 Aug 30;42(21):126122. doi: 10.1016/j.vaccine.2024.07.023. Epub 2024 Jul 28. PMID: 39074996.
Bailey H, Jonker MF, Pullenayegum E, Rencz F, Roudijk B. The EQ-5D-5L valuation study for Trinidad and Tobago. Health Qual Life Outcomes. 2024 Jul 2;22(1):51. doi: 10.1186/s12955-024-02266-7. PMID: 38956543; PMCID: PMC11218064.
Ahmed AM, Pullenayegum E, McDonald SD, Beltempo M, Premji SS, Shoukry R, Pole JD, Bacchini F, Shah PS, Pechlivanoglou P. Preterm Birth, Family Income, and Intergenerational Income Mobility. JAMA Netw Open. 2024 Jun 3;7(6):e2415921. doi: 10.1001/jamanetworkopen.2024.15921. PMID: 38857046; PMCID: PMC11165381.
Lamsal R, Yeh EA, Pullenayegum E, Ungar WJ. A Systematic Review of Methods and Practice for Integrating Maternal, Fetal, and Child Health Outcomes, and Family Spillover Effects into Cost-Utility Analyses. Pharmacoeconomics. 2024 Aug;42(8):843-863. doi: 10.1007/s40273-024-01397-5. Epub 2024 May 31. PMID: 38819718; PMCID: PMC11249496.
Lamsal R, Yeh EA, Pullenayegum E, Ungar WJ. A Systematic Review of Methods Used by Pediatric Cost-Utility Analyses to Include Family Pharmacoeconomics. 2024 Feb;42(2):199-217. doi: 10.1007/s40273-023-01331-1. Epub 2023 Nov 9. PMID: 37945777; PMCID: PMC10810985.
Nelson KE, Zhu J, Thomson J, Mahant S, Widger K, Feudtner C, Cohen E, Pullenayegum E, Feinstein JA. Recurrent Intensive Care Episodes and Mortality Among Children With Severe Neurologic Impairment. JAMA Netw Open. 2024 Mar 4;7(3):e241852. doi: 10.1001/jamanetworkopen.2024.1852. PMID: 38488795; PMCID: PMC10943411.
Krueger C, Nguyen EL, Mahant S, Borkhoff CM, Cichon J, Drouin O, Pound C, Quet J, Wahi G, Bayliss A, Vomiero G, Foulds J, Kanani R, Sakran M, Sehgal A, Pullenayegum E, Widjaja E, Reginald A, Wolter N, Parkin P, Gill PJ; Periorbital and Orbital Cellulitis (POC) Multicenter Study Group and the Canadian Paediatric Inpatient Research Network (PIRN); Periorbital and Orbital Cellulitis (POC) Multicenter Study Group and Canadian Pediatric Inpatient Research Network (PIRN). Association of empiric antibiotic selection and clinical outcomes in hospitalised children with severe orbital infections: a retrospective cohort study. Arch Dis Child. 2024 Apr 8:archdischild-2023-326175. doi: 10.1136/archdischild-2023-326175. Epub ahead of print. PMID: 38589203.
Anyiwe K, Erman A, Hassan M, Feld JJ, Pullenayegum E, Wong WWL, Sander B. Characterising the effectiveness of social determinants of health-focused hepatitis B interventions: a systematic review. Lancet Infect Dis. 2024 Jan 3:S1473-3099(23)00590-X. doi: 10.1016/S1473-3099(23)00590-X. Epub ahead of print. PMID: 38184004.
Nozawa T, Pullenayegum EM, Bell-Peter A, Marcuz JA, Whitney K, Vinik O, Shupak R, Dover S, Feldman BM. Disease activity trajectories in juvenile dermatomyositis from childhood to adulthood. Rheumatology (Oxford). 2024 Jan 12:keae027. doi: 10.1093/rheumatology/keae027. Epub ahead of print. PMID: 38216715.
Xie F, Xie S, Pullenayegum E, Ohinmaa A. Understanding Canadian stakeholders’ views on measuring and valuing health for children and adolescents: a qualitative study. Qual Life Res. 2024 Mar 5. doi: 10.1007/s11136-024-03618-y. Epub ahead of print. PMID: 38438665.

2023

Belza C, Pullenayegum E, Nelson KE, Aoyama K, Fu L, Buchanan F, Diaz S, Goldberg O, Guttmann A, Hepburn CM, Mahant S, Martens R, Nathwani A, Saunders NR, Cohen E. Severe Respiratory Disease Among Children With and Without Medical Complexity During the COVID-19 Pandemic. JAMA Netw Open. 2023 Nov 1;6(11):e2343318. doi: 10.1001/jamanetworkopen.2023.43318. PMID: 37962886; PMCID: PMC10646732.
Hayeems RZ, Luca S, Chad L, Quercia N, Xiao B, Hossain A, Meyn MS, Pullenayegum EM, Ungar WJ. Assessing the Performance of the Clinician-reported Genetic Testing Utility InDEx (C-): Further Evidence of Inter-rater Reliability. Clin Ther. 2023 Aug;45(8):729-735. doi: 10.1016/j.clinthera.2023.07.006. Epub 2023 Jul 27. PMID: 37516567.
McKerlie MF, Wolter NE, Mahant S, Cichon J, Widjaja E, Drouin O, Pound C, Quet J, Wahi G, Bayliss A, Vomiero G, Foulds JL, Kanani R, Sakran M, Sehgal A, Borkhoff CM, Pullenayegum EM, Reginald A, Parkin PC, Gill PJ; Periorbital and Orbital Cellulitis (POC); Multicentre Study Group and Canadian Pediatric Inpatient Research Network (PIRN). Abscess volume as a predictor of surgical intervention in children hospitalized with orbital cellulitis: A multicentre cohort study. Int J Pediatr Otorhinolaryngol. 2023 Aug;171:111629. doi: 10.1016/j.ijporl.2023.111629. Epub 2023 Jul 8. PMID: 37437497.
Ho M, Pullenayegum EM, Fuller-Thomson E. Is Social Participation Associated with Successful Aging among Older Canadians? Findings from the Canadian Longitudinal Study on Aging (CLSA). Int J Environ Res Public Health. 2023 Jun 6;20(12):6058. doi: 10.3390/ijerph20126058. PMID: 37372645; PMCID: PMC10298328.
Mac S, Evans G, Pullenayegum EM, Patel SN, Sander B. Healthcare costs and outcomes associated with laboratory-confirmed Lyme disease in Ontario, Canada: A population-based cohort study. PLoS One. 2023 Jun 22;18(6):e0286552. doi: 10.1371/journal.pone.0286552. PMID: 37347742; PMCID: PMC10286989.
Jiang R, Pullenayegum EM, Shaw JW, Mühlbacher A, Lee TA, Walton S, Kohlmann T, Norman R, Pickard AS. Comparison of Preferences and Data Quality between Discrete Choice Experiments Conducted in Online and Face-to-Face Respondents. Med Decis Making. 2023 Aug;43(6):667-679. doi: 10.1177/0272989X231171912. Epub 2023 May 18. PMID: 37199407; PMCID: PMC10422849.
Nguyen EL, Hersi L, Mahant S, Cichon J, Drouin O, Pound C, Quet J, Wahi G, Bayliss A, Vomiero G, Foulds JL, Kanani R, Sakran M, Sehgal A, Borkhoff CM, Pullenayegum EM, Widjaja E, Reginald A, Wolter NE, Oni S, Anwar R, Louriachi H, Ge Y, Kirolos N, Patel A, Jasani H, Kornelsen E, Chugh A, Gouda S, Akbaroghli S, McKerlie M, Parkin PC, Gill PJ. Variation in the Management of Hospitalized Children With Orbital Cellulitis Over 10 Years. Hosp Pediatr. 2023 May 1;13(5):375-391. doi: 10.1542/hpeds.2022-007006. PMID: 37122049.
Peel JK, Pullenayegum EM, Naimark D, Aversa M, Liu M, Del Sorbo L, Barrett K, Sander B, Keshavjee S. Evaluating the Impact of Ex Vivo Lung Perfusion on Organ Transplantation: A Retrospective Cohort Study. Ann Surg. 2023 Aug 1;278(2):288-296. doi: 10.1097/SLA.0000000000005887. Epub 2023 Apr 19. PMID: 37073734; PMCID: PMC10321509.
Rae S, Ong F, Dennis CL, Hamilton J, Pullenayegum EM, Maguire J, Birken C. Parent involvement in child anthropometric measurement. BMC Prim Care. 2023 Apr 5;24(1):89. doi: 10.1186/s12875-023-02028-2. PMID: 37016320; PMCID: PMC10073622.
Tang TS, Liao F, Webber D, Gold N, Cao J, Dominguez D, Gladman D, Knight A, Levy DM, Ng L, Paterson AD, Touma Z, Urowitz MB, Wither J, Silverman ED, Pullenayegum EM, Hiraki LT. Genetics of longitudinal kidney function in children and adults with systemic lupus erythematosus. Rheumatology (Oxford). 2023 Mar 14:kead119. doi: 10.1093/rheumatology/kead119. Epub ahead of print. PMID: 36916720.
Jakubczyk M, Lipman SA, Roudijk B, Norman R, Pullenayegum EM (CA), Yang Y, Gu NY, Stolk E. Modifying the Composite Time Trade-Off Method to Improve Its Disccriminatory Power. Value Health. 2023 Feb;26(2):280-291. doi: 10.1016/j.jval.2022.08.011. Epub 2022 Oct 14. PMID: 36244905.
Lim LSH, Lokku A, Pullenayegum EM, Ringold S. Probability of Response in the First Sixteen Weeks After Starting Biologics: An Analysis of Juvenile Idiopathic Arthritis Biologics Trials. Arthritis Care Res (Hoboken). 2023 Jun;75(6):1238-1249. doi: 10.1002/acr.25003. Epub 2023 Jan 18. PMID: 36651601.
Tsiplova K, Ungar WJ, Szatmari P, Cost KT, Pullenayegum EM (CA), Duku E, Volden J, Smith IM, Waddell C, Zwaigenbaum L, Bennett TA, Elsabbagh M, Georgiades S, Zaidman-Zait A. Measuring the association between behavioural services and outcomes in young children with autism spectrum disorder. Res Dev Disabil. 2023 Jan;132:104392. doi: 1016/j.ridd.2022.104392. PMID: 36493738
Hayeems RZ, Luca S, Hurst ACE, Cochran M, Owens C, Hossain A, Chad L, Meyn MS, Pullenayegum EM, Ungar WJ, Bick D. Applying the Clinician-reported Genetic testing Utility InDEx (C-GUIDE) to genome sequencing: further evidence of validity. Eur J Hum Genet. 2022 Dec;30(12):1423-1431. doi: 10.1038/s41431-022-01192-w. Epub 2022 Oct 4. PMID: 36195708; PMCID: PMC9712646.
Yan J, Xie S, Johnson JA, Pullenayegum EM, Ohinmaa A, Bryan S, Xie F. Canada population norms for the EQ-5D-5L. Eur J Health Econ. 2023 Feb 24. doi: 10.1007/s10198-023-01570-1. Epub ahead of print. PMID: 36828968.
Furlong W, Rae C, Feeny D, Ghotra S, Breakey VR, Carter T, Pai N, Pullenayegum EM (CA), Xie F, Barr R. Generic Health-Related Quality of Life Utility Measure for Preschool Children (Health Utilities Preschool): Design, Development, Properties. Value Health. 2023 Feb;26(2):251-260. doi: 10.1016/j.jval.2022.07.015. Epub 2022 Aug 26. PMID: 36031479

2022

Lim, LSH., Lokku, A^*., Pullenayegum, E. (CA), & Ringold, S. (2022). Probability of Response in the First Sixteen Weeks After Starting Biologics: An Analysis of Juvenile Idiopathic Arthritis Biologics Trials. Arthritis care & research, 10.1002/acr.25003. Advance online publication.
Loeb M, Bartholomew A, Hashmi M, Tarhuni W, Hassany M, Youngster I, Somayaji R, Larios O, Kim J, Missaghi B, Vayalumkal JV, Mertz D, Chagla Z, Cividino M, Ali K, Mansour S, Castellucci LA, Frenette C, Parkes L, Downing M, Muller M, Glavin V, Newton J, Hookoom R, Leis JA, Kinross J, Smith S, Borhan S, Singh P, Pullenayegum EM (CA), Conly J. Medical Masks Versus N95 Respirators for Preventing COVID-19 Among Health Care Workers: A Randomized Trial. Ann Intern Med. 2022 Dec;175(12):1629-1638. doi: 10.7326/M22-1966. PMID: 36442064
Hayeems RZ, Luca S, Hurst ACE, Cochran M, Owens C, Hossain A, Chad L, Stephen Meyn M, Pullenayegum EM (CA), Ungar WJ, Bick D. Applying the Clinician-reported Genetics testing Utility InDEx (C-GUIDE) to genome sequencing: further evidence of validity. Eur J Hum Genet. 2022 Dec;30(12):1423-1431. doi: 10.1038/s41431-022-01192-w. PMID: 36195708
Krakowski AD^ǂ, Cost KT, Szatmari P, Anagnostou E, Crosbie J, Schachar R, Duku E, Georgiades S, Ayub M, Kelley E, Nicholson R, Pullenayegum EM (CA), Barnett-Tapia C. Characterizing the ASD-ADHD phenotype: measurement structure and invariance in a clinical sample. J Child Psychol Psychiatry. 2022 Dec;63(12):1534-1534. doi: 10.1111/jcpp.13609. PMID: 35342939
Wee WB, Leigh MW, David SD, Rosenfeld M, Sullivan KM, Sawras MG, Ferkol TW, Knowles MR, Milla C, Sagel SD, Zariwala MA, Pullenayegum EM (CA), Dell SD. Association of Neonatal Hospital Length of Stay with Lung Function in Primary Ciliary Dyskinesia. Ann Am Thorac Soc. 2022 Nov;19(11):1865-1870. doi: 10.1513/AnnalsATS.202202-116OC. PMID: 35657736
Peel JK^ǂ, Keshavjee S, Naimark D, Liu M, Del Sorbo L, Cypel M, Barrett K, Pullenayegum EM (CA), Sander B. Determining the impact of ex-vivo lung perfusion on hospital costs for lung transplantation: A retrospective cohort study. J Heart Lung Transplant. 2022 Nov 9;S1053-2498(22)02198-2. doi: 10.1016/j.healun.2022.10.016. Online ahead of print. PMID: 36411188
Ho M^ǂ, Pullenayegum EM (CA), Burnes D, Fuller-Thomson E. Successful Aging among Immigrants and Canadian-Born Older Adults: Findings from the Canadian Longitudinal Study on Aging (CLSA). Int J Environ Res Public Health. 2022 Oct 13;19(20):13199. doi: 10.3390/ijerph192013199. PMID: 36293780
Switzer C, Verschoor CP, Pullenayegum E, Singh P, Loeb M. Adjuvant-attenuated symptom severity of influenza infections in vaccinated children. Infect Med (Beijing). 2022 Sep 15;1(3):163-170. doi: 10.1016/j.imj.2022.09.002. PMID: 38077624; PMCID: PMC10699701.
Gill PJ, Drouin O, Pound C, Quet J, Wahi G, Bayliss A, Vomiero G, Foulds J, Kanani R, Sakran M, Sehgal A, Pullenayegum EM (CA), Widjaja E, Reginald A, Wolter NE, Oni S, Anwar R, Jasani H, Kornelsen E, Chugh A, Gouda S, Akbaroghli S, McKerlie M, Parkin PC, Mahant S, Orbital Cellulitis (POC) Multicenter Study Group; Canadian Pediatric Inpatient Research Network (PIRN). Factors Associated with Surgery and Imaging Characteristics in Severe Orbital Infections. J Pediatr. 2022 Sep;248:66-73.e7. doi: 10.1016/j.jpeds.2022.05.010. PMID: 35568061
Baribeau DA^ǂ, Vigod S, Brittain H, Vaillancourt T, Szatmari P, Pullenayegum E (SRA). Application of Transactional (Cross-lagged panel) Models in Mental Health Research: An Introduction and Review of Methodological Considerations. J Can Acad Child Adolesc Psychiatry. 2022 Aug;31(3):124-134. Epub 2022 Aug 1. PMID: 35919904; PMCID: PMC9275371.
Lim LSH, Shobhan S, Lokku A^*, Ringold S, Pullenayegum E (SRA). Latent classes of early response trajectories to biologics initiation in juvenile idiopathic arthritis: an analysis of four trials. Pediatr Rheumatol Online J. 2022 Jul 30;20(1):57. doi: 10.1186/s12969-022-00719-1. PMID: 35907978; PMCID: PMC9338501.
Baribeau DA^ǂ, Vigod SN, Pullenayegum E (CA), Kerns CM, Vaillancourt T, Duku E, Smith IM, Volden J, Zwaigenbaum L, Bennett T, Elsabbagh M, Zaidman-Zait A, Richard AE, Szatmari P. Developmental cascades between insistence on sameness behaviour and anxiety symptoms in autism spectrum disorder. Eur Child Adolesc Psychiatry. 2022 Jul 24. doi: 10.1007/s00787-022-02049-9. Online ahead of print.
Chung KY^ǂ, Gebretekle GB, Howard A, Pullenayegum E (CA), Eshete M, Forrest CR, Sander B. Patient-Proxy and Societal Perspectives of Quality-of-Life Utilities in Children With Cleft Lip and Palate Managed With Surgical Repair vs No Repair in Ethiopia. JAMA Netw Open. 2022 Jul 1;5(7):e2220900. doi: 10.1001/jamanetworkopen.2022.20900.
Wee WB, Leigh MW, Davis SD, Rosenfeld M, Sullivan KM, Sawras MG, Ferkol TW, Knowles MR, Milla C, Sagel SD, Zariwala MA, Pullenayegum E (CA), Dell SD., Association of Neonatal Hospital Length of Stay with Lung Function in Primary Ciliary Dyskinesia. Ann Am Thorac Soc. 2022 Jun 3. doi: 10.1513/AnnalsATS.202202-116OC. Online ahead of print. PMID: 35657736
Roumeliotis N, Frndova H, Pullenayegum E, Taddio A, Rochon P, Parshuram CS., Dosing of enteral acetaminophen in critically ill children: a cohort study. Arch Dis Child. 2022 Apr;107(4):388-393. doi: 10.1136/archdischild-2021-321952. Epub 2021 Sep 27. PMID: 34580057
Dover S, Stephens S, Clairman H, Abesamis A, Jazi OA, Babij S, Marcuz JA, Naraidoo N, Pan J, Pullenayegum E, Rumsey D, Whitney K, Feldman BM., Feasibility of the wingate anaerobic exercise test as a clinical measure in patients with juvenile dermatomyositis. Pediatr Rheumatol Online J. 2022 Mar 28;20(1):21. doi: 10.1186/s12969-022-00679-6. PMID: 35346243
Krakowski AD, Cost KT, Szatmari P, Anagnostou E, Crosbie J, Schachar R, Duku E, Georgiades S, Ayub M, Kelley E, Nicolson R, Pullenayegum E, Barnett-Tapia C., Characterizing the ASD-ADHD phenotype: measurement structure and invariance in a clinical sample. J Child Psychol Psychiatry. 2022 Mar 27. doi: 10.1111/jcpp.13609. Online ahead of print. PMID: 35342939
Hayeems RZ, Luca S, Ungar WJ, Venkataramanan V, Tsiplova K, Bashir NS, Costain G, Inglese C, McNiven V, Quercia N, Shugar A, Yoon G, Cytrynbaum C, Dupuis L, Shao Z, Hewson S, Shuman C, Aul R, Liston E, Babul-Hirji R, Bushby A, Pullenayegum E, Chad L, Meyn MS., The Clinician-reported Genetic testing Utility InDEx (C-GUIDE): Preliminary evidence of validity and reliability. Genet Med. 2022 Feb;24(2):430-438. doi: 10.1016/j.gim.2021.10.005. Epub 2021 Nov 30. PMID: 34906486

2021

Mac S, Evans GA, Patel SN, Pullenayegum EM, Sander B., Estimating the population health burden of Lyme disease in Ontario, Canada: a microsimulation modelling approach. CMAJ Open. 2021 Nov 16;9(4):E1005-E1012. doi: 10.9778/cmajo.20210024. Print 2021 Oct-Dec. PMID: 34785530
Loeb M, Russell ML, Kelly-Stradiotto C, Fuller N, Fonseca K, Earn DJD, Chokani K, Babiuk L, Neupane B, Singh P, Pullenayegum E. Adjuvanted trivalent influenza vaccine versus quadrivalent inactivated influenza vaccine in Hutterite Children: A randomized clinical trial. Vaccine. 2021 Nov 16;39(47):6843-6851. doi: 10.1016/j.vaccine.2021.10.035. Epub 2021 Oct 23. PMID: 34702621
Stimec J, Dover S, Pullenayegum E, Blanchette VS, Doria AS, Feldman BM, Carcao M, Rivard GE, Israels SJ, Chan AK, Steele M, Cloutier S, Klaassen RJ, Price VE, Sinha R, Laferriere N, Paradis E, Wu JKM, Babyn P., Magnetic resonance imaging in boys with severe hemophilia A: Serial and end-of-study findings from the Canadian Hemophilia Primary Prophylaxis Study. Res Pract Thromb Haemost. 2021 Oct 16;5(7):e12565. doi: 10.1002/rth2.12565. eCollection 2021 Oct. PMID: 34703973
Avila L, Amiri N, De R, Vincelli J, Pullenayegum EM, Williams S, Brandao LR., Characteristics of Upper and Lower Extremity Deep Vein Thrombosis and Predictors of Post-Thrombotic Syndrome in Children. Blood Adv. 2021 Oct 12;5(19):3737-3747. doi: 10.1182/bloodadvances.2021004727. Online ahead of print. PMID: 34474480
Tarride JE, Doumouras AG, Hong D, Paterson JM, Tibebu S, Nguyen F, Perez R, Taylor VH, Xie F, Boudreau V, Pullenayegum E, Urbach DR, Anvari M., Comparison of 4-Year Health Care Expenditures Associated With Roux-en-Y Gastric Bypass vs Sleeve Gastrectomy. JAMA Netw Open. 2021 Sep 1;4(9):e2122079. doi: 10.1001/jamanetworkopen.2021.22079. PMID: 34499137
Avila L, Amiri N, De R, Vincelli J, Pullenayegum E, Brandão LR. Compression garments for the management of pediatric post-thrombotic syndrome: A prospective longitudinal study. J Thromb Haemost. 2021 Dec;19(12):3073-3079. doi: 10.1111/jth.15507. Epub 2021 Aug 30. PMID: 34418289
Nelson KE, Chakravarti V, Diskin C, Thomson J, Cohen E, Mahant S, Feudtner C, Widger K, Pullenayegum E, Berry JG, Feinstein JA., Validation of Neurologic Impairment Diagnosis Codes as Signifying Documented Functional Impairment in Hospitalized Children. Acad Pediatr., 2021 Jul 25:S1876-2859(21)00376-4. doi: 10.1016/j.acap.2021.07.014. Online ahead of print. PMID: 34320414
Morris SK, Pell LG, Rahman MZ, Mahmud AA, Shi J, Ahmed T, Dimitris MC, Gubbay JB, Islam MM, Kashem T, Keya FK, Mohsin M, Pullenayegum E, Science M, Shanta SS, Sumiya MK, Zlotkin S, Roth DE., Effects of Maternal Vitamin D Supplementation During Pregnancy and Lactation on Infant Acute Respiratory Infections: Follow-up of a Randomized Trial in Bangladesh. J Pediatric Infect Dis Soc., 2021 Oct 27;10(9):901-909. doi: 10.1093/jpids/piab032. . PMID: 34213544
Goren R, Pullenayegum E, Blanchette VS, Dover S, Carcao M, Israels SJ, Chan A, Rivard GE, Steele M, Cloutier S, Klaassen RJ, Sinha R, Price VE, Laferriere N, Paradis E, Wu JK, Feldman BM., Patterns of joint damage in severe haemophilia A treated with prophylaxis. Haemophilia. 2021 Jul;27(4):666-673. doi: 10.1111/hae.14345. Epub 2021 May 20.PMID: 34015166
Avila ML, Amiri N, Pullenayegum E, Sealey VA, De R, Williams S, Vincelli J, Brandão LR., Diagnostic Value of D-dimers for Limb Deep Vein Thrombosis in Children: A Prospective Study. Am J Hematol.2021 Aug 1;96(8):954-960. doi:10.1002/ajh.26212.Epub 2021 May 15. PMID: 33930198
Stremler R, Micsinszki S, Adams S, Parshuram C, Pullenayegum E, Weiss SK., Objective Sleep Characteristics and Factors Associated With Sleep Duration and Waking During Pediatric Hospitalization. JAMA Netw Open. 2021 Apr 1;4(4):e213924. doi: 10.1001/jamanetworkopen.2021.3924. PMID: 33792731
Almaghlouth I, Johnson SR, Pullenayegum E, Gladman D, Urowitz M., Immunoglobulin levels in systemic lupus erythematosus: A narrative review. Lupus. 2021 May;30(6):867-875. doi: 10.1177/09612033211004714. Epub 2021 Mar 28. PMID: 33779380
Almaghlouth I, Su J, Johnson SR, Pullenayegum E, Gladman D, Urowitz M. Acquired low immunoglobulin levels and risk of clinically relevant infection in adult patients with systemic lupus erythematosus: a cohort study. Rheumatology (Oxford)2021 Mar 2;60(3):1456-1464. doi: 10.1093/rheumatology/keaa641. Online ahead of print. PMID: 33006611
Heath A, Rios JD, Pullenayegum E, Pechlivanoglou P, Offringa M, Yaskina M, Watts R, Rimmer S, Klassen TP, Coriolano K, Poonai N; PERC-KIDSCAN Ketodex Study Group., The intranasal dexmedetomidine plus ketamine for procedural sedation in children, adaptive randomized controlled non-inferiority multicenter trial (Ketodex): a statistical analysis plan. Trials. 2021 Jan 6;22(1):15. doi: 10.1186/s13063-020-04946-3. PMID: 33407719
Baribeau DA, Vigod S, Pullenayegum E, Kerns CM, Mirenda P, Smith IM, Vaillancourt T, Volden J, Waddell C, Zwaigenbaum L, Bennett T, Duku E, Elsabbagh M, Georgiades S, Ungar WJ, Zaidman Zait A, Szatmari P. Co-occurring trajectories of anxiety and insistence on sameness behaviour in autism spectrum disorder. Br J Psychiatry.2021 Jan;218(1):20-27. doi: 10.1192/bjp.2020.127. Online ahead of print. PMID: 32641181

2020

Heath A, Yaskina M, Pechlivanoglou P, Rios D, Offringa M, Klassen TP, Poonai N, Pullenayegum E, A Bayesian response-adaptive dose-finding and comparative effectiveness trial. Clin Trials. 2021 Feb;18(1):61-70. doi: 10.1177/1740774520965173. Epub 2020 Nov 24. PMID: 33231105
Avila ML, Amiri N, Pullenayegum E, Blanchette V, Imbach P, Kühne T; Intercontinental Cooperative ITP Study Group. Long-term outcomes after splenectomy in children with immune thrombocytopenia: an update on the registry data from the Intercontinental Cooperative ITP Study Group. Haematologica. 2020 Nov 1;105(11):2682-2685. doi: 10.3324/haematol.2019.236737. PMID: 33131262
Roumeliotis N, Pullenayegum E, Rochon P, Taddio A, Parshuram C, A modified Delphi to define drug dosing errors in pediatric critical care. BMC Pediatr. 2020 Oct 21;20(1):488. doi: 10.1186/s12887-020-02384-3. PMID: 33087096
Dover S, Stephens S, Schneiderman JE, Pullenayegum E, Wells GD, Levy DM, Marcuz JA, Whitney K, Schulze A, Tein I, Feldman BM. The effect of creatine supplementation on muscle function in childhood myositis: A randomized, double-blind, placebo-controlled feasibility study. J Rheumatol. 2021 Mar;48(3):434-441.. doi: 10.3899/jrheum.191375. Epub 2020 Aug 1. PMID: 32739897
Tarride JE, Doumouras AG, Hong D, Paterson JM, Tibebu S, Perez R, Ma J, Taylor VH, Xie F, Boudreau V, Pullenayegum E, Urbach DR, Anvari M. Association of Roux-en-Y Gastric Bypass With Postoperative Health Care Use and Expenditures in Canada. JAMA Surg. 2020 Sep 1;155(9):e201985. doi: 10.1001/jamasurg.2020.1985. Epub 2020 Sep 16. PMID: 32697298.
Mac S, Bahia S, Simbulan F, Pullenayegum EM, Evans GA, Patel SN, Sander B. Long-Term Sequelae and Health-Related Quality of Life Associated With Lyme Disease: A Systematic Review. Clin Infect Dis. 2020 Jul 11;71(2):440-452. doi: 10.1093/cid/ciz1158. PMID: 31773171
Almaghlouth I, Pullenayegum E, Gladman DD, Urowitz MB, Johnson SR. Propensity Score Methods in Rare Disease. A Demonstration Using Observational Data in Systemic Lupus Erythematosus. J Rheumatol. 2021 Mar;48(3):321-325. doi: 10.3899/jrheum.200254. Epub 2020 Jul 1. PMID: 32611674
Heath A, Offringa M, Pechlivanoglou P, Rios JD, Klassen TP, Poonai N, Pullenayegum E; KidsCAN PERC Innovative Paediatric Clinical Trials Team. Determining a Bayesian predictive power stopping rule for futility in a non-inferiority trial with binary outcomes. Contemp Clin Trials Commun. 2020 Apr 8;18:100561. doi: 10.1016/j.conctc.2020.100561. eCollection 2020 Jun. PMID: 32300671
Hayeems RZ, Luca S, Ungar WJ, Bhatt A, Chad L, Pullenayegum E, Meyn MS. Response to Rubanovich et al. Genet Med. 2020 Mar;22(3):667-668. doi: 10.1038/s41436-019-0700-1. Epub 2019 Nov 19. PMID: 31740736
Dover S, Blanchette VS, Wrathall D, Pullenayegum E, Kazandjian D, Song B, Hawes SA, Cloutier S, Rivard GE, Klaassen RJ, Paradis E, Laferriere N, Stain AM, Chan AK, Israels SJ, Sinha R, Steele M, Wu JKM, Feldman BM. Hemophilia prophylaxis adherence and bleeding using a tailored, frequency-escalated approach: The Canadian Hemophilia Primary Prophylaxis Study. Res Pract Thromb Haemost. 2020 Jan 29;4(2):318-325. doi: 10.1002/rth2.12301. eCollection 2020 Feb. PMID: 32110763

2019

Gill PJ, Parkin PC, Begum N, Drouin O, Foulds J, Pound C, Quet J, Vomiero G, Wahi G, Sakran M, Kozlowski N, Bayliss A, Kanani R, Sehgal A, Pullenayegum EM, Reginald A, Wolter N, Mahant S. Care and outcomes of Canadian children hospitalised with periorbital and orbital cellulitis: protocol for a multicentre, retrospective cohort study. BMJ Open. 2019 Dec 22;9(12):e035206. doi: 10.1136/bmjopen-2019-035206. PMID: 31871262
Brent SE, Pullenayegum E, Russell ML, Loeb M. Effect of seasonal influenza vaccination on influenza symptom severity among children in Hutterite communities: Follow-up study of a randomized trial. Influenza Other Respir Viruses. 2020 Jan;14(1):28-36. doi: 10.1111/irv.12689. Epub 2019 Nov 8. PMID: 31702876
Hayeems RZ, Luca S, Pullenayegum E, Meyn MS, Ungar WJ. Genome Diagnostics: Novel Strategies for Measuring Value. J Manag Care Spec Pharm. 2019 Oct;25(10):1096-1101. doi: 10.18553/jmcp.2019.25.10.1096. PMID: 31556822
Baribeau DA, Vigod S, Pullenayegum E, Kerns CM, Mirenda P, Smith IM, Vaillancourt T, Volden J, Waddell C, Zwaigenbaum L, Bennett T, Duku E, Elsabbagh M, Georgiades S, Ungar WJ, Zaidman-Zait A, Szatmari P. Repetitive Behavior Severity as an Early Indicator of Risk for Elevated Anxiety Symptoms in Autism Spectrum Disorder. J Am Acad Child Adolesc Psychiatry. 2020 Jul;59(7):890-899.e3. doi: 10.1016/j.jaac.2019.08.478. Epub 2019 Sep 18. PMID: 31541676
Avila ML, Feldman BM, Pullenayegum E, Lumia C, Montoya MI, Vincelli J, Williams S, Brandão LR. Post-thrombotic syndrome in children: Measurement properties of CAPTSure, a new diagnostic tool. Res Pract Thromb Haemost. 2019 Aug 28;3(4):652-657. doi: 10.1002/rth2.12251. eCollection 2019 Oct. PMID: 31624784
Hayeems RZ, Luca S, Ungar WJ, Bhatt A, Chad L, Pullenayegum E, Meyn MS. The development of the Clinician-reported Genetic testing Utility InDEx (C-GUIDE): a novel strategy for measuring the clinical utility of genetic testing. Genetics in Medicine. 2020 Jan; 22(1):95-101 doi: 10.1038/s41436-019-0620-0. Epub 2019 Jul 31. PubMed PMID: 3136318
Mtaweh H, Soto Aguero MJ, Campbell M, Allard JP, Pencharz P, Pullenayegum E, Parshuram CS. Systematic review of factors associated with energy expenditure in the critically ill. Clin Nutr ESPEN. 2019 Oct;33:111-124. doi: 10.1016/j.clnesp.2019.06.009. Epub 2019 Jul 11. PMID: 31451246
Mtaweh H, Garros C, Ashkin A, Tuira L, Allard JP, Pencharz P, Pullenayegum E, Joffe A, Parshuram CS. An Exploratory Retrospective Study of Factors Affecting Energy Expenditure in Critically Ill Children. Journal of Parenteral and Enteral Nutrition. 2020 Mar;44(3):507-515. doi: 10.1002/jpen.1673. Epub 2019 Jul 2. PMID: 31267545.
Marshall DA, Ferrusi IL, Trudeau M, Leighl NB, Hoch JS, Grazziotin LR, Khong H, Pullenayegum E, Earle CC. Adherence to human epidermal growth factor receptor-2 testing and adjuvant trastuzumab treatment guidelines in Ontario. Journal of Oncology Pharmacy Practice. 2020 Mar; 26(2): 379-385 doi: 10.1177/1078155219850299. Epub 2019 Jun 2. PubMed PMID: 31156051
Pickard AS, Law EH, Jiang R, Pullenayegum E, Shaw JW, Xie F, Oppe M, Boye KS, Chapman RH, Gong CL, Balch A, Busschbach JJV. United States Valuation of EQ-5D-5L Health States Using an International Protocol. Value Health. 2019 Aug;22(8):931-941. doi: 10.1016/j.jval.2019.02.009. Epub 2019 May 25. PMID: 31426935
Carsley S, Parkin PC, Tu K, Pullenayegum E, Persaud N, Maguire JL, Birken CS; TARGet Kids! Collaboration. Reliability of routinely collected anthropometric measurements in primary care. BMC Medical Research Methodology. 2019 Apr 24;19(1):84. doi: 10.1186/s12874-019-0726-8. https://pubmed.ncbi.nlm.nih.gov/31014250/ PMID: 31014250.
Vuichard-Gysin D, Mertz D, Pullenayegum EM, Singh P, Smieja M, Loeb M. Development and validation of clinical prediction models to distinguish influenza from other viruses causing acute respiratory infections in children and adults. PLoS One. 2019 Feb 11; 14(2):e0212050. doi:10.1371/journal.pone.0212050. eCollection 2019. PMID: 30742654
Loeb M, Dang AD, Thiem VD, Thanabalan V, Wang B, Nguyen NB, Tran HTM, Luong TM, Singh P, Smieja M, Maguire J, Pullenayegum EM. Effect of Vitamin D supplementation to reduce respiratory infections in children and adolescents in Vietnam: A randomized controlled trial. Influenza and Other Respiratory Viruses. 2019 Mar; 13(2):176-183. doi: 10.1111/irv.12615. Epub 2019 Jan 4. PubMed PMID: 30328294

2018

Carsley S, Tu K, Parkin PC, Pullenayegum E, Birken CS. Overweight and obesity in preschool aged children and risk of mental health service utilization. International Journal of Obesity (London). 2019 Jul; 43(7):1325-1333 doi: 10.1038/s41366-018-0280-1. Epub 2018 Dec 13. PMID: 30546134
Rae C, Furlong W, Feeny D, Couchman R, Silverman L, Sallan S, Laverdiere C, Clavell L, Michon B, Kelly K, Larsen E, Pullenayegum E, Athale U, Barr R. Health Status and Health-related Quality of Life Measurement in Pediatric Cancer Clinical Trials: An Examination of the DFCI 00-01 Acute Lymphoblastic Leukemia Protocol. Journal of Pediatric Hematology Oncology. 2018 Nov; 40(8):580-587. doi: 10.1097/MPH.0000000000001235. PMID: 29901560
Loeb M, Russell ML, Neupane B, Thanabalan V, Singh P, Newton J, Pullenayegum EM. A randomized, blinded, placebo-controlled trial comparing antibody responses to homeopathic and conventional vaccines in university students. Vaccine. 2018 Nov 19; 36(48):7423-7429. doi: 10.1016/j.vaccine.2018.08.082. Epub 2018 Oct 21. PMID: 30352746
Eny KM, Chen S, Anderson LN, Chen Y, Lebovic G, Pullenayegum E, Parkin PC, Maguire JL, Birken CS; TARGet Kids! Collaboration. Breastfeeding duration, maternal body mass index, and birth weight are associated with differences in body mass index growth trajectories in early childhood. The American Journal of Clinical Nutrition. 2018 Apr 1; 107(4):584-592. doi: 10.1093/ajcn/nqx081. PMID: 29635496
Deakin CT, Campanilho-Marques R, Simou S, Moraitis E, Wedderburn LR, Pullenayegum E, Pilkington CA; Juvenile Dermatomyositis Research Group. Efficacy and Safety of Cyclophosphamide Treatment in Severe Juvenile Dermatomyositis Shown by Marginal Structural Modeling. Arthritis & Rheumatology. 2018 May; 70(5):785-793. doi: 10.1002/art.40418. Epub 2018 Mar 25. PMID: 29342499;
Lim LSH, Pullenayegum EM, Feldman BM, Lim L, Gladman DD, Silverman ED. From Childhood to Adulthood: Disease Activity Trajectories in Childhood-Onset Systemic Lupus Erythematosus. Arthritis Care & Research (Hoboken). 2018 May; 70(5): 750-757. doi: 10.1002/acr.23319. Epub 2018 Mar 25. PMID: 28704581
Carsley S, Birken CS, Parkin P, Pullenayegum E, Tu K. Completeness and accuracy of anthropometric measurements in electronic medical records for children attending primary care. Journal of Innovation in Health Informatics. 2018 Mar 9; 25(1):963. doi: 10.14236/jhi.v25i1.963. PMID: 29717951

2017

Huff H, Merchant AT, Lonn E, Pullenayegum E, Smaill F, Smieja M. Vitamin D and progression of carotid intima-media thickness in HIV-positive Canadians. HIV Medicine. 2018 Feb; 19(2):143-151. doi: 10.1111/hiv.12563. Epub 2017 Nov 6. PMID: 29110385.
Tian SY, Silverman ED, Pullenayegum EM, Brown PE, Beyene J, Feldman BM. Comparative Effectiveness of Mycophenolate Mofetil for the Treatment of Juvenile-Onset Proliferative Lupus Nephritis. Arthritis Care and Research (Hoboken). 2018 May; 69(12):1887-1894. Epub 2017 Nov 2. doi: 10.1002/acr.23215. PubMed PMID: 28182833.
Keilty K, Cohen E, Spalding K, Pullenayegum EM, Stremler R. Sleep disturbance in family caregivers of children who depend on medical technology. Archives of Disease in Childhood. 2018 Feb; 103(2):137-142. doi: 10.1136/archdischild-2016-312205. Epub 2017 Oct 26. PMID: 29074731
Carsley S, Birken CS, Tu K, Pullenayegum EM, Parkin PC. Examining growth monitoring practices for children in primary care. Archives of Disease in Childhood. 2018 Apr; 103(4):406-407. doi: 10.1136/archdischild-2017-314016. Epub 2017 Oct 26. PMID: 29074730
Cheng S, Qureshi M, Pullenayegum E, Haynes A, Chan KK. Do patients with reduced or excellent performance status derive the same clinical benefit from novel systemic cancer therapies? A systematic review and meta-analysis. ESMO Open. 2017 Sep 21; 2(4):e000225. doi: 10.1136/esmoopen-2017-000225. eCollection 2017. PMID: 29209535;
Lim LSH, Pullenayegum E, Lim L, Gladman D, Feldman B, Silverman E. From Childhood to Adulthood: The Trajectory of Damage in Patients With Juvenile-Onset Systemic Lupus Erythematosus. Arthritis Care Res (Hoboken). 2017 Nov;69(11):1627-1635. doi: 10.1002/acr.23199. Epub 2017 Sep 26. PMID: 28118527
Tsoi B*, Akioyamen LE, Bonner A, Frankfurter C, Levine M, Pullenayegum E, Goeree R, O’Reilly D. Comparative Efficacy of Angiotensin II Antagonists in Essential Hypertension: Systematic Review and Network Meta-analysis of Randomised Controlled Trials. Heart, Lung and Circulation. 2018 Jun; 27(6): 666-682. doi: 10.1016/j.hlc.2017.06.721. Epub 2017 July 14. PMID: 28807582
Lim LS, Pullenayegum E, Moineddin R, Gladman DD, Silverman ED, Feldman BM. Methods for analyzing observational longitudinal prognosis studies for rheumatic diseases: a review & worked example using a clinic-based cohort of juvenile dermatomyositis patients. Pediatric Rheumatology Online Journal. 2017 Mar 29; 15(1):18. doi: 10.1186/s12969-017-0148-2. PMID: 28356102;
Tanvejsilp P, Pullenayegum E, Loeb M, Dushoff J, Xie F. Role of pharmaceutical care for self-administered pulmonary tuberculosis treatment in Thailand. Journal of Clinical Pharmacy and Therapeutics. 2017 Jun; 42 (3):337-344. doi: 10.1111/jcpt.12519. Epub 2017 Mar 19. PMID: 28317143.
Stremler R, Haddad S, Pullenayegum EM, Parshuram C. Psychological Outcomes in Parents of Critically Ill Hospitalized Children. Journal of Pediatric Nursing. 2017 May – Jun; 34:36-43. doi: 10.1016/j.pedn.2017.01.012. Epub 2017 Mar 6.https://pubmed.ncbi.nlm.nih.gov/28274664/ PMID: 28274664.

2016

Cheng J, Iorio A, Marcucci M, Romanov V, Pullenayegum EM, Marshall JK, Thabane L. Bayesian approach to the assessment of the population-specific risk of inhibitors in hemophilia A patients: a case study. Journal of Blood Medicine. 2016 Oct 25;7:239-253. doi: 10.2147/JBM.S103087. eCollection 2016. PMID: 27822129.
Xie F, Pullenayegum E, Pickard AS, Ramos Goñi JM, Jo MW, Igarashi A. Transforming Latent Utilities to Health Utilities: East Does Not Meet West. Health Econ. 2017 Dec;26(12):1524-1533. doi: 10.1002/hec.3444. Epub 2016 Oct 16. PMID: 27747973
Morris SK, Pell LG, Rahman MZ, Dimitris MC, Mahmud A, Islam MM, Ahmed T, Pullenayegum E, Kashem T, Shanta SS, Gubbay J, Papp E, Science M, Zlotkin S, Roth DE. Maternal vitamin D supplementation during pregnancy and lactation to prevent acute respiratory infections in infancy in Dhaka, Bangladesh (MDARI trial): protocol for a prospective cohort study nested within a randomized controlled trial. BMC Pregnancy Childbirth. 2016 Oct 13;16(1):309. doi: 10.1186/s12884-016-1103-9. PMID: 27737646
Ahmed RJ, Gafni A, Hutton EK, Hu ZJ, Pullenayegum E, von Dadelszen P, Rey E, Ross S, Asztalos E, Murphy KE, Menzies J, Sanchez JJ, Ganzevoort W, Helewa M, Lee SK, Lee T, Logan AG, Moutquin JM, Singer J, Thornton JG, Welch R, Magee LA. The Cost Implications of Less Tight Versus Tight Control of Hypertension in Pregnancy (CHIPS Trial). Hypertension. 2016 Oct; 68(4):1049-55. doi: 10.1161/HYPERTENSIONAHA.116.07466. Epub 2016 Aug 22.PMID: 27550914.
Jamal AN, Feldman BM, Pullenayegum E. The Use of Neck Support Pillows and Postural Exercises in the Management of Chronic Neck Pain. Journal of Rheumatology. 2016 Oct; 43(10):1871-1873. doi: 10.3899/jrheum.151368. Epub 2016 Aug 1. PMID: 27481909.
Loeb M, Russell ML, Manning V, Fonseca K, Earn DJ, Horsman G, Chokani K, Vooght M, Babiuk L, Schwartz L, Neupane B, Singh P, Walter SD, Pullenayegum E. Live Attenuated Versus Inactivated Influenza Vaccine in Hutterite Children: A Cluster Randomized Blinded Trial. Annals of Internal Medicine. 2016 Nov 1;165(9):617-624. doi: 10.7326/M16-0513. Epub 2016 Aug 16. PMID: 27538259.
Cheng J, Pullenayegum E, Marshall JK, Iorio A, Thabane L. Impact of including or excluding both-armed zero-event studies on using standard meta-analysis methods for rare event outcome: a simulation study. BMJ Open. 2016 Aug 16; 6(8):e010983. doi: 10.1136/bmjopen-2015-010983. PMID: 27531725.
Crivianu-Gaita V, Rivard GE, Carcao M, Teitel J, St-Louis J, Blanchette V, Pullenayegum E, Abad A, Feldman BM. Pilot study of once-a-day prophylaxis for youth and young adults with severe haemophilia A. Haemophilia. 2016 Sep; 22(5):e401- 5. doi: 10.1111/hae.13058. Epub 2016 Aug 1. PMID: 27481574.
Fotis L, Shaikh N, Baszis K, French A, Tarr P, Grevich S, Lee P, Ringold S, Leroux B, Leahey H, Yuasa M, Foster J, Sokolove J, Lahey L, Robinson W, Newsom J, Stevens A, Karasawa R, Tamaki M, Tanaka M, Sato T, Yudoh K, Jarvis JN, Moncrieffe H, Bennett MF, Tsoras M, Luyrink L, Xu H, Prahalad S, Morris P, Dare J, Nigrovic PA, Rosenkranz M, Becker M, O’Neil KM, Griffin T, Lovell DJ, Grom AA, Medvedovic M, Thompson SD, Zhu L, Jiang K, Wong L, Buck MJ, Chen Y, Moncrieffe H, Brungs L, Liu T, Wang T, Jarvis JN, Alsaeid K, Alfailakawi J, Alenezi H, Alsaeed H, Beukelman T, Natter M, Ilowite N, Mieszkalski K, Burrell G, Best B, Bristow H, Carr S, Dennos A, Kaufmann R, Kimura Y, Schanberg L, Blier PR, Boneparth A, Wenderfer SE, Moorthy LN, Radhakrishna SM, Sagcal-Gironella ACP, von Scheven E, Gedik KC, Siddique S, Aguiar CL, Erkan D, Cohen E, Lee Y, Dossett M, Mehta D, Davis R, Gilbert M, Goilav B, Meidan E, Hsu J, Boneparth A, Chua A, Ardoin S, Wenderfer SE, Von Scheven E, Ruth NM, Hui-Yuen J, Gedik KC, Bermudez L, Cook A, Imundo L, Starr A, Eichenfield A, Askanase A, Janow G, Schanberg LE, Setoguchi S, Hasselblad V, Mellins ED, Schneider R, Kimura Y; The CARRA Legacy Registry Investigators, Kimura Y, Grevich S, Beukelman T, Morgan E, Graham TB, Ibarra M, Ruas YS, Klein-Gitelman M, Onel K, Prahalad S, Punaro M, Ringold S, Toib D, Van Mater H, Weiss JE, Weiss PF, Mieszkalski K, Schanberg LE, Kwok TSH, Bisaillon J, Smith C, Brosseau L, Stinson J, Huber AM, Duffy CM, April KT, Lewandowski LB, Scott C, Li SC, Torok KS, Rabinovich CE, Hong SD, Becker ML, Dedeoglu F, Ibarra MF, Ferguson PJ, Fuhbrigge RC, Stewart KG, Pope E, Laxer RM, Mason TG, Higgins GC, Li X, Punaro MG, Tomlinson G, Pullenayegum E, Matelski J, Schanberg L, Feldman BM, Manthiram K, Correa H, Edwards K, Oberle EJ, Bayer M, Co DO, Baris HE, Chiu Y, Huber A, Kim S, Oberle EJ, Beukelman T, Orandi AB, Baszis KW, Dharnidharka V, Hoeltzel MF; for the CARRA JDM Committee, Reed A, Huber A, Tomlinson G, Pullenayegum E, Matelski J, Goh YI, Schanberg L, Feldman BM, Schnabel A, Range U, Hahn G, Siepmann T, Berner R, Hedrich CM, Stevens B, Torok KS, Li S, Hershey N, Curran M, Higgins G, Moore K, Rabinovich E, Stevens AM; for the CARRA Registry Investigators, Stinson J, Connelly M, Huber A, Luca N, Spiegel L, Tsimicalis A, Luca S, Tajuddin N, Berard R, Barsalou J, Campillo S, Dancey P, Duffy C, Feldman B, Johnson N, McGrath P, Shiff N, Tse S, Tucker L, Victor C, Stinson J, Lalloo C, Harris L, Cafazzo J, Spiegel L, Feldman B, Luca N, Laxer R, Bullock DR, Vehe RK, Zhang L, Correll CK, Ganguli S, Shenberger M, Korumilli R, Gottlieb B, Rodriguez M, de Ranieri D, Onel K, Wagner-Weiner L, Tesher M, Wojcicki ER, Maletta KL, Co DO, Malloy M, Thomson S, Olson JC, Wenderfer SE, Gilbert M, Hsu J, Sule S, Rubinstein TB, Goilav B, Okamura DM, Chua A, Greenbaum LA, Lane JC, von Scheven E, Ardoin SP, Ruth NM, Woo JMP, Malloy MM, Jegers JA, Hahn DJ, Hintermeyer MK, Martinetti SM, Heckel GR, Roth-Wojcicki EL, Co DO. Proceedings of the 2016 Childhood Arthritis and Rheumatology Research Alliance (CARRA) Scientific Meeting : Toronto, Canada. 14-17 April 2016 Pediatr Rheumatol Online J. 2016 Jul 12;14 Suppl 1(Suppl 1):41. doi: 10.1186/s12969-016-0098-0. PMID: 27409414
Avila ML, Pullenayegum E, Williams S, Yue N, Krol P, Brandão LR. Post-thrombotic syndrome and other outcomes of lower extremity deep vein thrombosis in children. Blood. 2016 Oct 6;128(14):1862-1869. Doi: 10.1182/blood-2016-03-704585. Epub 2016 Jul 29. PMID: 27474755.
Portwine C, Rae C, Davis J, Teira P, Schechter T, Lewis V, Mitchell D, Wall DA, Pullenayegum EM, Barr RD. Health-Related Quality of Life in Survivors of High-Risk Neuroblastoma After Stem Cell Transplant: A National Population-Based Perspective. Pediatric Blood & Cancer. 2016 Sep; 63(9):1615-21. doi: 10.1002/pbc.26063. Epub 2016 May 20. PMID: 27203368.
Avila ML, Pullenayegum E, Shammas A, Brandão LR. An evidence-based perspective on warfarin and the growing bone: response to Sugiyama et al. Osteoporosis International. 2016 Sep;27(9):2885-2886. doi: 10.1007/s00198-016-3587-6. Epub 2016 Apr 18. PMID: 27091740.
Avila ML, Pullenayegum E, Williams S, Shammas A, Stimec J, Sochett E, Marr K, Brandão LR. Timing of low bone mineral density and predictors of bone mineral density trajectory in children on long-term warfarin: a longitudinal study. Osteoporosis International. 2016 Apr; 27(4); 1547-1557. doi: 10.1007/s00198-015-3411-8. Epub 2015 Nov 16.PMID: 26572757.
Xie F, Pullenayegum E, Gaebel K, Bansback N, Bryan S, Ohinmaa A, Poissant L, Johnson JA. How different are composite and traditional TTO valuations of severe EQ- 5D-5L States? Quality of Life Research. 2016 Aug; 25(8); 2101-2108. doi: 10.1007/s11136-016-1242-5. Epub 2016 Feb 13. PMID: 26875190.
Oremus M, Xie F, Pullenayegum E, Gaebel K. Can the general public use vignettes to discriminate between Alzheimer’s disease health states? BMC Geriatrics. 2016 Feb 3; 16(1):36. doi: 10.1186/s12877-016-0207-4. PMID: 26842500.
Xie F, Pullenayegum E, Gaebel K, Bansback N, Bryan S, Ohinmaa A, Poissant L, Johnson JA; Canadian EQ-5D-5L Valuation Study Group. A Time Trade-off-derived Value Set of the EQ-5D-5L for Canada. Medical Care. 2016 Jan; 54(1):98-105. doi: 10.1097/MLR.0000000000000447. PMID: 26492214.

2015

Sayah FA, Bansback N, Bryan S, Ohinmaa A, Poissant L, Pullenayegum E, Xie F, Johnson JA. Determinants of time trade-off valuations for EQ-5D-5L health states: data from the Canadian EQ-5D-5L valuation study. Quality of Life Research. 2016 Jul; 25(7); 1679-1685. doi: 10.1007/s11136-015-1203-4. Epub 2015 Dec 10. PMID: 26659899.
Akioyamen L, Levine M, Sherifali D, O’Reilly D, Frankfurter C, Pullenayegum EM, Goeree R, Tsoi B. Cardiovascular and cerebrovascular outcomes of long-term angiotensin receptor blockade: meta-analyses of trials in essential hypertension. Journal of the American Society of Hypertension. 2016 Jan;10(1):55-69.e1. doi: 10.1016/j.jash.2015.11.005. Epub 2015 Dec 1. PMID: 26684588.
Valentino PL, Feldman BM, Walters TD, Griffiths AM, Ling SC, Pullenayegum EM, Kamath BM. Abnormal Liver Biochemistry Is Common in Pediatric Inflammatory Bowel Disease: Prevalence and Associations. Inflammatory Bowel Diseases. 2015 Dec; 21(12): 2848-56. doi: 10.1097/MIB.0000000000000558 PMID: 26273817
Nayiager T, Duckworth J, Pullenayegum E, Whitton A, Hollenberg R, Horsman J,Furlong W, Spitzer R, Barr R. Exploration of Morbidity in a Serial Study of Long-Term Brain Tumor Survivors: A Focus on Pain. Journal of Adolescent and Young Adult Oncology. 2015 Sep; 4(3):129-36. doi: 10.1089/jayao.2015.0026. Epub 2015 Aug 17. PMID: 26812665.
Duckworth J, Nayiager T, Pullenayegum EM, Whitton A, Hollenberg R, Horsman J, Furlong W, Spitzer R, Barr RD. Health-related Quality of Life in Long-term Survivors of Brain Tumors in Childhood and Adolescence: A Serial Study Spanning a Decade. Journal of Pediatric Hematology/Oncology. 2015 July; 37(5):362-7. doi: 10.1097/MPH.0000000000000365. PMID: 26018809.
Stephens S, Takken T, Esliger DW, Pullenayegum E, Beyene J, Tremblay M, Schneiderman J, Biggar D, Longmuir P, McCrindle B, Abad A, Ignas D, Van Der Net J, Feldman B. Validation of Accelerometer Prediction Equations in Children With Chronic Disease. Pediatric Exercise Science. 2016 Feb; 28(1); 117-32. doi: 10.1123/pes.2014- 0185. Epub 2015 Jul 1. PMID: 26182189
Lutsiv O, McKinney B, Foster G, Taylor VH, Pullenayegum E, McDonald SD. Pregnancy complications associated with the co-prevalence of excess maternal weight and depression. Int J Obes (Lond). 2015 Dec;39(12):1710-6. doi: 10.1038/ijo.2015.119. Epub 2015 Jun 22. PMID: 26095247

2014

Lim LS, Lee SJ, Feldman BM, Gladman DD, Pullenayegum EM, Uleryk E, Silverman ED. Systematic review of the quality of prognosis studies in systemic lupus erythematosus. Arthritis Care & Research (Hoboken). 2014 Oct; 66(10):1536-41 doi: 10.1002/acr.22322. PMID: 24643975.
Choong K, Foster G, Fraser DD, Hutchison JS, Joffe AR, Jouvet PA, Menon K, Pullenayegum EM, Ward RE; conducted on behalf of the Canadian Critical Care Trials Group. Acute Rehabilitation Practices in Critically Ill Children: A Multicenter Study. Pediatric Critical Care Medicine. 2014 Jul;15(6):e270-9. doi: 10.1097/PCC.000000000000016. PMID: 24777303.
Müller D, Pullenayegum EM, Gandjour A. Impact of small study bias on cost- effectiveness acceptability curves and value of information analyses. European Journal of Health Economics. 2015 Mar; 16(2):219-23. doi: 10.1007/s10198-014-0607-3 Epub 2014 May 20. PMI 24840608.
Goodall EC, Granados AC, Luinstra K, Pullenayegum EM, Coleman BL, Loeb M, Smieja M. Vitamin D3 and gargling for the prevention of upper respiratory tract infections: a randomized controlled trial. BMC Infectious Diseases. 2014 May 19; 14(1):273. doi: 10.1186/1471-2334-14-273. PMID: 24885201.
Stremler R, Dhukai Z, Pullenayegum EM, Weston J, Wong L, Parshuram C. Sleep, Sleepiness, and Fatigue Outcomes for Parents of Critically Ill Children. Pediatric Critical Care Medicine. 2014 Feb; 15(2); e56-65. doi: 10.1097/01.pcc.0000436198.15337.15. PMID: 24196009.
Agoritsas T, Iserman E, Hobson N, Cohen N, Cohen A, Roshanov PS, Perez M, Cotoi C, Parrish R, Pullenayegum EM, Wilczynski NL, Iorio A, Haynes RB. Increasing the quantity and quality of searching for current best evidence to answer clinical questions: protocol and intervention design of the MacPLUS FS Factorial Randomized Controlled Trials. Implementation Science. 2014 Sep 20;9:125. doi: 10.1186/s13012-014-0125-9.
PMID: 25239537

2013

Lutsiv O, Giglia L, Pullenayegum EM, Foster G, Vera C, Chapman B, Fusch C, McDonald SD. A Population-Based Cohort Study of Breastfeeding According to Gestational Age at Term Delivery. Journal of Pediatrics. 2013 Nov; 163(5); 1283-8. doi: 10.1016/j.jpeds.2013.06.056. Epub 2013 Aug 3. PMID: 23919904.
Holbrook A, Lexchin J, Pullenayegum EM, Campbell C, Marlow B, Troyan S, Weijer C, Blackmer J, Brazil K, Willison D. What do Canadians think about physician- pharmaceutical industry interactions? Health Policy. 2013 Oct; 112(3); 255-63. doi: 10.1016/j.healthpol.2013.04.020. Epub 2013 May 24. PMID: 23711633.
Hong C, Kim S, Curnew G, Schulman S, Pullenayegum EM, Holbrook A. Validation of a patient decision aid for choosing between dabigatran and warfarin for atrial fibrillation. Journal of Population Therapeutics and Clinical Pharmacology. 2013; 20(3):e229-37. Epub 2013 Sep 6. PMID: 24163147.
Lutsiv O, Pullenayegum EM, Foster G, Vera C, Giglia L, Chapman B, Fusch C, McDonald S. Women’s intentions to breastfeed: a population-based cohort study. BJOG. 2013 Nov; 120(12); 1490-8. doi: 10.1111/1471-0528.12376. Epub 2013 Jul 17. PMID: 23859024.
Chu R, Mills EJ, Beyene J, Pullenayegum EM, Bakanda C, Nachega JB, Devereaux PJ, Thabane L. Impact of tuberculosis on mortality among HIV-infected patients receiving antiretroviral therapy in Uganda: a prospective cohort analysis. AIDS Research and Therapy. 2013 Jul 13; 10(1):19. doi: 10.1186/1742-6405-10-19. PMID: 23849301.
Oremus M, Tarride JE, Pullenayegum EM, Clayton N, Study Group CW, Raina P. Caregivers’ willingness-to-pay for Alzheimer’s disease medications in Canada. Dementia (London). 2015 Jan; 14(1):63-79. doi: 10.1177/1471301213490709 Epub 2013 Jun 5. PMID: 24339090.
Zorko DJ, Choong K, Gilleland J, Agar B, Baker S, Brennan C, Pullenayegum EM. Urgent ultrasound guided hemodynamic assessments by a pediatric medical emergency team: a pilot study. PLoS One. 2013 Jun 25; 8(6):e66951. doi: 10.1371/journal.pone.0066951. Print 2013. PMID: 23825593.
Lam J, Gomes T, Juurlink DN, Mamdani MM, Pullenayegum EM, Kearon C, Spencer FA, Paterson M, Zheng H, Holbrook AM. Hospitalization for hemorrhage among warfarin recipients prescribed amiodarone. American Journal of Cardiology. 2013 Aug 1; 112(3):420-3. doi: 10.1016/j.amjcard.2013.03.051. Epub 2013 May 8. PMID: 23664078.
Xie F, Pullenayegum EM, Gaebel K, Oppe M, Krabbe PF. Eliciting preferences to the EQ-5D-5L health states: discrete choice experiment or multiprofile case of best-worst scaling? European Journal of Health Economics. 2014 Apr; 15(3); 281-288. doi: 10.1007/s10198-013-0474-3 Epub 2013 Apr 4. PMID: 23553075.
Xie F, Gaebel K, Perampaladas K, Doble B, Pullenayegum EM. Comparing EQ-5D Valuation Studies: A Systematic Review and Methodological Reporting Checklist. Medical Decision Making. 2014 Jan; 34(1); 8-20. doi: 10.1177/0272989X13480852. Epub 2013 Mar 22. PMID: 23525701.
Oremus M, Tarride JE, Pullenayegum EM, Clayton N; Canadian Willingness-to-Pay Study Group, Raina P. Patients’ Willingness-to-Pay for an Alzheimer’s Disease Medication in Canada. Patient. 2013; 6(3):161-8. doi: 10.1007/s40271-013-0014-3. PMID: 23716166.
Ferrusi IL, Earle CC, Trudeau M, Leighl NB, Pullenayegum EM, Khong H, Hoch JS, Marshall DA. Closing the personalized medicine information gap: HER2 test documentation practice. American Journal of Managed Care. 2013 Jan; 19(1):838-44. PMID: 23379747.

2012

McCarron CE, Pullenayegum EM, Thabane L, Goeree R, Tarride JE. The Impact of Using Informative Priors in a Bayesian Cost-Effectiveness Analysis: An Application of Endovascular versus Open Surgical Repair for Abdominal Aortic Aneurysms in High- Risk Patients. Medical Decision Making. 2013 Apr; 33(3); 437-50. doi: 10.1177/0272989X12458457 Epub 2012 Oct 9. PMID: 23054366.
Rae C, Furlong W, Horsman J, Pullenayegum EM, Demers C, St-Louis J, Lillicrap D, Barr R. Bleeding disorders, menorrhagia and iron deficiency: impacts on health-related quality of life. Haemophilia. 2013 May; 19(3); 385-91. doi: 10.1111/hae.12014. Epub 2012 Sep 21. PMID: 22994803
Celluci T, Tyrell PN, Pullenayegum EM, Benseler SM. Von Willebrand factor antigen – a possible biomarker of disease activity in childhood central nervous system vasculitis? Rheumatology (Oxford). 2012 Oct; 51(10); 1838-45. doi: 10.1093/rheumatology/kes156. Epub 2012 Jun 26. PMID: 22740622.
Lustiv O, Bracken K, Pullenayegum EM, Sword W, Taylor VH, McDonald SD. Little Congruence Between Health Care Provider and Patient Perceptions of Counselling on Gestational Weight Gain. Journal of Obstetrics and Gynaecology Canada. 2012 Jun; 34(6): 518-24. doi: 10.1016/S1701-2163(16)35267-7. PMID: 22673167.
McDonald SD, Pullenayegum EM, Chapman B, Vera C, Giglia L, Fusch C, Foster G. Prevalence and predictors of exclusive breastfeeding at hospital discharge. Obstetrics & Gynecology. 2012 Jun; 119(6): 1171-9. doi: 10.1097/AOG.0b013e318256194b. PMID: 22617582.
Hopkins RB, Tarride JE, Leslie WD, Metge C, Lix LM, Morin S, Finlayson G, Azimaee M, Pullenayegum EM, Goeree R, Adachi JD, Papaioannou A, Thabane L. Estimating the excess costs for patients with incident fractures, prevalent fractures, and nonfracture osteoporosis. Osteoporosis International. 2013 Feb; 24(2); 581-93. doi: 10.1007/s00198- 012-1997-7. Epub 2012 May 10. PMID: 22572964.
Cheng J, Pullenayegum EM, Marshall DA, Marshall JK, Thabane L. An empirical comparison of methods for analyzing correlated data from a discrete choice survey to elicit patient preference for colorectal cancer screening. BMC Medical Research Methodology. 2012 Feb 20; 12: 15. doi: 10.1186/1471-2288-12-15.PMID: 22348526.
McDonald SD, Pullenayegum EM, Bracken K, Chen AM, McDonald H, Malott A, Hutchison R, Haley S, Lutsiv O, Taylor VH, Good C, Hutton E, Sword W. Comparison of midwifery, family medicine, and obstetric patients’ understanding of weight gain during pregnancy: a minority of women report correct counselling. Journal of Obstetrics and Gynaecology Canada. 2012 Feb; 34(2):129-35. doi: 10.1016/S1701-2163(16)35155-6. PMID: 22340061.
Kwan MY, Carney J, Faulkner GE, Pullenayegum EM. Physical activity and other health-risk behaviors during the transition into early adulthood: a longitudinal cohort study. American Journal of Preventitive Medicine. 2012 Jan: 42(1):14-20. doi: 10.1016/j.amepre.2011.08.026. PMID: 22176841.

2011

Tarride J, Oremus M, Pullenayegum EM, Clayton N, Raina P. How does the Canadian general public rate moderate Alzheimer’s disease? Journal of Aging Research. 2011; 2011:602470. Epub 2011 Dec 20 PMID: 22229093.
Holbrook A, Pullenayegum EM, Thabane L, Troyan S, Foster G, Keshavjee K, Chan D, Dolovich L, Gerstein H, Demers C, Curnew G. Shared Electronic Vascular Risk Decision Support in Primary Care: Computerization of Medical Practices for the Enhancement of Therapeutic Effectiveness (COMPETE III) Randomized Trial. Archives of Internal Medicine. 2011 Oct 24; 171(19):1736-44. doi: 10.1001/archinternmed.2011.471. PMID: 22025430
McCarron CE, Pullenayegum EM, Thabane L, Goeree R, Tarride JE. Bayesian Hierarchical models combining different study types and adjusting for covariate imbalances: a simulation study to assess model performance. PLOS ONE 2011; 6(10):e25635. Epub 2011 Oct 10 PMID: 22016772.
Lam C, Manlhiot C, Pullenayegum EM, Feldman BM. Efficacy of intravenous Ig therapy in juvenile dermatomyositis. Annals of Rheumatic Diseases. 2011 Dec; 70(12):2089-94. doi: 10.1136/ard.2011.153718. 2011 Oct 6. PMID: 21978999.
Sherifali D, Greb JL, Amirthavasar G, Hunt D, Haynes RB, Harper W, Holbrook A, Capes S, Goeree R, O’Reilly D, Pullenayegum EM, Gerstein HC. Effect of computer- generated tailored feedback on glycemic control in people with diabetes in the community: a randomized controlled trial. Diabetes Care. 2011 Aug; 34(8):1794-8. doi: 10.2337/dc11-0006. Epub 2011 Jun 16. PMID: 21680723.
Xie F, Pullenayegum EM, Li SC, Hopkins R, Thumboo J, Lo NN. Use of a Disease-Specific Instrument in Economic Evaluations: Mapping WOMAC onto the EQ- 5D Utility Index. Value Health 2010 Dec; 13(8):873-8. doi: 10.111/j. 1524- 4733.2010.00770.x. PMID: 20667055.
McDonald SD, Pullenayegum EM, Taylor V, Lustiv O, Bracken K, Good C, Hutton E, Sword W. Despite 2009 guidelines few women are counseled correctly about weight gain during pregnancy. American Journal of Obstetrics & Gynecology. 2011 Oct; 205(4):333.e1-6. doi: 10.1016/j.ajog.2011.05.039. Epub 2011 May 27. PMID: 21784404.
Hopkins RB, Pullenayegum EM, Goeree R, Adachi JD, Papaioannou A, Leslie WD, Tarride JE, Thabane L. Estimation of the lifetime risk of hip fracture for women and men in Canada. Osteoporosis International. 2012 Mar; 23(3): 921-7. doi: 10.1007/s00198-011- 1652-8. Epub 2011 May 11. PMID: 21557096.
Ye C, Giangregorio L, Holbrook A, Pullenayegum EM, Goldsmith CH, ThabaneL. Data Withdraw in Randomized Controlled Trials: Defining the Problem and Proposing Solutions: a commentary. Contemporary Clinical Trials. 2011 May; 32(3); 318-22. doi: 10.1016/j.cct.2011.01.016. Epub 2011 Feb 4. PMID: 21300179.
Ratchada K, Rahman A, Pullenayegum EM, Sant Anna GM. Positive airway pressure levels and pneumothorax: a case-control study in very low birth weight infants. Journal of Maternal-Fetal & Neonatal Medicine. 2011 Jul; 24(7):912-6. doi: 10.3109/14767058.2010.535877. Epub 2011 Apr 4. PMID: 21463217.
Hang MX, Blanchette VS, Pullenayegum EM, McLimont M, Feldman BM, Canadian Hemophilia Primary Prophylaxis Study Group. Age at first joint bleed and bleeding severity in boys with severe hemophilia A: Canadian Hemophilia Primary Prophylaxis Study. Journal of Thrombosis and Haemostasis. 2011 May;9(5):1067-9. doi: 10.1111/j.1538-7836.2011.04228.x. PMID: 21320278.
Ion A, Wenjie C, Elston D, Pullenayegum EM, Smaill F, Smieja M. A Comparison of the MOD-HIV and SF-12Y2 for measuring health-related quality of life men and women living with HIV/AIDS. AIDS Research and Therapy. 2011 Jan 27; 8(1):5. doi: 10.1186/1742-6405-8-5. PMID: 21272358.
O’Reilly DJ, Xie F, Pullenayegum EM, Gerstein HC, Greb J, Blackhouse GK, Tarride JE, Bowen J, Goeree RA. Estimation of the impact of diabetes-related complications on health utilities for patients with type 2 diabetes in Ontario, Canada. Quality of Life Research. 2011 Aug;20(6):939-43. doi: 10.1007/s11136-010-9828-9. Epub 2011 Jan 8. PMID: 21221816.
Hopkins RB, Goeree R, Pullenayegum EM, Adachi JD, Papaioannou A, Xie F, Thabane L. The relative efficacy of nine osteoporosis medications for reducing the rate of fractures in post-menopausal women. BMC Musculoskeletal Disorders. 2011 Sep 26;12:209. doi:10.1186/1471-2474-12-209. PMID: 21943363.
Chu R, Thabane L, Ma J, Holbrook A, Pullenayegum EM, Devereaux PJ. Comparing methods to estimate treatment effects on a continuous outcome in multicentre randomized controlled trials: A simulation study. BMC Medical Research Methodology. 2011 Feb 21;11:21. doi: 10.1186/1471-2288-11-21. PMID: 21338524.
Thabane L, Wells G, Cook R, Platt R, Pogue J, Pullenayegum EM, Matthews D, McCready T, Devereaux PJ, Cairns JA, Yusuf S, CANadian Network and Centre for Trials Internationally (CANNeCTIN) Investigators. Canadian-led capacity-building in biostatistics and methodology in cardiovascular and diabetes trials: the CANNeCTIN Biostatistics and Methodological Innovation Working Group. Trials. 2011 Feb 18;12:48. doi: 10.1186/1745-6215-12-48. PMID: 21332987.

2010

Xie F, Lo N, Pullenayegum EM, Tarride JE, O’Reilly D, Goeree R, Lee HP. Evaluation of Health Outcomes in Osteoarthritis Patients after Total Knee Replacement: A Two-Year Follow-up. Health and Quality of Life Outcomes 2010 Aug 19; 8:87. doi: 10.1186/1477-7525-8-87. PMID: 20723239.
Soreni N, Noseworthy MD, Konyer NB, Pullenayegum E, Schachar R. Interindividual, repositioning and time-of-day effects on single voxel proton MR Spectroscopy of the anterior cingulate cortex. Journal of Magnetic Resonance Imaging 2010 Aug; 32(2):276-82. doi: 10.1002/jmri.22264. PMID: 20677251.
McCarron CE, Pullenayegum EM, Thabane L, Goeree R, Tarride JE. The importance of adjusting for potential confounders in Bayesian hierarchial models synthesising evidence from randomised and non randomised studies: an application comparing treatments for abdominal aortic aneurysms. BMC Med Res Methodol. 2010 Jul 9;10:64. doi: 10.1186/1471-2288-10-64. PMID: 20618973.
Bridle BW, Stephenson KB, Boudreau JE, Koshy S, Kazdlan N, Pullenayegum EM, Brunelliere J, Bramson JL, Lichty BD, Wan Y. Potentiating cancer immunotherapy using an oncolytic virus. Mol Ther. 2010 Aug; 18(8):1430-9. doi: 10.1038/mt.2010.98. Epub 2010 Jun 15. PMID: 20551919.
Sherifali D, Nerenberg K, Pullenayegum E, Cheng J, Gerstein HC. The effect of oral antidiabetic agents on A1C levels: a systematic review and meta-analysis. Diabetes Care. 2010 Aug; 33(8):1859-64. doi: 10.2337/dc09-1727. Epub 2010 May 18. PMID: 20484130.
Briel M, Meade M, Mercat A, Brower RG, Talmor D, Walter SD, Slutsky AS, Pullenayegum EM, Zhou Q, Cook D, Brochard L, Richard JC, Lamontagne F, Bhatnagar N, Stewart TE, Guyatt G. Higher vs lower positive end-expiratory pressure in patients with acute lung injury and acute respiratory distress syndrome: systematic review and meta-analysis. JAMA. 2010 Mar 3;303(9):865-73. doi: 10.1001/jama.2010.218. PMID: 20197533

2009 and earlier

McCarron CE, Pullenayegum EM, Marshall DA, Goeree R, Tarride JE. Handling Uncertainty in Economic Evaluations of Patient Level Data: A Review of the Use of Bayesian Methods to Inform Health Technology Assessments. Int J Technol Assess Health Care 2009 Oct;25(4):546-54. doi: 10.1017/S0266462309990316. PMID: 19845985
Yang RC, Young A, Nevis IFP, Lee D, Jain AK, Dominic A, Klarenbach S, Pullenayegum EM, Guyatt G, Garg AX. Life Insurance for Living Kidney Donors: A Canadian Undercover Investigation. Am J Transplant. 2009 Jul;9(7):1585-90. doi: 10.1111/j.1600-6143.2009.02679.x. Epub 2009 Jun 10. PMID: 19519823
Thabane L, Walter SD, Hanna S, Goldsmith CH, Pullenayegum EM. Developing a biostatistical collaboration course in a health science research methodology program. Journal of Statistics Education. 2008; 16(2). https://doi.org/10.1080/10691898.2008.11889564
Humphrey A, Williams J, Pinto EM, Bolton PF. A prospective longitudinal study of early cognitive development in tuberous sclerosis – a clinic based study. Eur Child Adolesc Psychiatry. 2004 Jun;13(3):159-65. doi: 10.1007/s00787-004-0383-1. PMID: 15254843
Johnson P, Richard C, Ravid A, Spencer L, Pinto EM, Hanna M, Cohen Z, McLeod R. Female infertility after ileal pouch-anal anastomosis for ulcerative colitis. Dis Colon Rectum. 2004 Jul;47(7):1119-26. doi: 10.1007/s10350-004-0570-7. Epub 2004 May 28. PMID: 15164254
Pinto EM, Huppert FA, Morgan K, Mrc Cfas, Brayne CE. Neutrophil counts, monocyte counts and cardiovascular disease in the elderly. Exp Gerontol. 2004 Apr;39(4):615-9. doi: 10.1016/j.exger.2003.12.011. PMID: 15050297.
Beardsall K, White DK, Pinto EM, Kelsall AW. Pericardial effusion and cardiac tamponade as complications of neonatal long lines: are they really a problem? Arch Dis Child Fetal Neonatal Ed. 2003 Jul;88(4):F292-5. doi: 10.1136/fn.88.4.f292. PMID: 12819160
Huppert FA, Pinto EM, Morgan K, Medical Research Council Cognitive Function and Ageing Study, Brayne CE. Immune measures which predict 9-year survival in an elderly population sample. Advances in Cell Aging and Gerontology 2003; 13: 17-28. doi:10.1016/S1566-3124(02)13002-1.
Huppert FA, Pinto EM, Morgan K, Brayne C. Survival in a population sample is predicted by proportions of lymphocyte subsets. Mech Aging Dev. 2003 Apr;124(4):449-51. doi: 10.1016/s0047-6374(03)00021-6. PMID: 12714252.
Dawes EN, Clarke SA, Lamanuzzi N, Pinto EM, Brooks RA, Rushton N. The response of macrophages to particles of resorbable polymers and their degradation products. J Mater Sci Mater Med. 2003 Mar;14(3):271-5. doi: 10.1023/a:1022892925877. PMID: 15348474.
Ng CS, Doyle TC, Pinto EM, Courtney HM, Miller R, Bull RK, Freeman AH, Dixon AK. Caecal carcinomas in the elderly: useful signs in minimal preparation CT. Clin Radiol. 2002 May;57(5):359-64. doi: 10.1053/crad.2001.0841. PMID: 12014932. (joint winner of the 2002 Robert and Elma Kemp Harper Prize).
Ng CS, Doyle TC, Pinto EM, Courtney HM, Bull RK, Prevost AT, Campbell GA, Freeman AH, Dixon AK. Evaluation of CT in identifying colorectal carcinoma in the frail and disabled patient. Eur Radiol. 2002 Dec;12(12):2988-97. doi: 10.1007/s00330-002-1367-5. PMID: 12439581
Huntly BJ, Bench AJ, Delabesse E, Reid AG, Li J, Scott MA, Campbell L, Byrne J, Pinto EM, Brizard A, Niedermeiser D, Nacheva EP, Guilhot F, Deininger M, Green AR. Derivative chromosome 9 deletions in chronic myeloid leukemia: poor prognosis is not associated with loss of ABL-BCR expression, elevated BCR-ABL levels, or karyotypic instability. Blood. 2002 Jun 15;99(12):4547-53. doi: 10.1182/blood.v99.12.4547. PMID: 12036887

Publications

Longitudinal data subject to irregular observation

Health Utilities

Knowledge Translation

Collaborations