Find a complete list of published work in MyBibliography.

Lung Formation

Tibboel, J., Groenman, FA., Selvaratnam, J., Wang, I., Tseu, I., Huang, Z., Caniggia, I., Luo, D., van Tuyl, M., Ackerley, C., de Jongste, J., Tibboel, D., Post. M. HIF-1 stimulates postnatal lung development but does not prevent O2-induced alveolar injury. Am J Respir Cell Mol Biol 52(4):448-458, 2015.

Joza, S., Wang, J., Fox, E., Hillman, V., Ackerley, C., Post, M. Loss of Semaphorin-Neuropilin-1 signaling causes dysmorphic vascularization reminiscent of alveolar capillary dysplasia. Am. J. Pathol.181:2003-2017, 2012.

Motoyama, J., Liu, J., Mo, R. Ding, Q., Post. M., Hui, C.-c. Essential functions of Gli2 and Gli3 zinc finger genes in the formation of lung, trachea and esophagus. Nature genetics 20, 54-57, 1998.

Lung Lipid Metabolism

Snoek, K.G., Reiss, I.K.M., Tibboel, J., van Rosmalen, J., Capolupo, I., van Heijst, A., Schaible, T., Post, M., Tibboel, D. Sphingolipids in congenital diaphragmatic hernia; results from an international multicenter study. PLoS One 11(5):e0155136, 2016.

Lee, J, Yeganeh, B., Ermini, L., Post, M. Sphingolipids as Cell Fate Regulators in Lung Development and Disease. Apoptosis 20 (5), 740-757, 2015

Tibboel, J., Joza, S., Reiss, I., de Jongste, J., Post, M. Amelioration of hyperoxia-induced lung injury in newborn mice using a sphingolipid-based intervention. Eur Respir J. 42(3):776-784, 2013.

Ventilation and Lung Development

Otulakowski, G., Engelberts, D., Arima,H., Hirate, H., Bayir, Post, M., Kavanagh, B.P. α-Tocopherol Transfer Protein Mediates Protective Hypercapnia in Murine Ventilator-Induced Lung Injury. Thorax. 2017 Feb 3. pii: thoraxjnl-2016-209501.

Kroon, A.A., DelRiccio, V., Tseu, I., Kavanagh, B.P., Post, M. Mechanical Ventilation-Induced Apoptosis in Newborn Rat Lung is mediated via FasL/Fas Pathway. Am J Physiol Lung 305(11):L795-804, 2013.

Copland, I., Engelberts, D., McKerlie, C., Belik J., Kavanagh, B.P., Post, M. Early changes in lung gene expression due to high tidal volume. Am J Respir Crit Care 168, 1051-10591, 2003.

Stem Cells and Lung Regeneration

Litvack, M., Wigle, TJ, Wang, J., Ackerley, C., Grunebaum, E., Post, M. Alveolar-like stem cell-derived Mybneg macrophages promote recovery and survival in airway disease. Am J Respir Crit. Care Med. 193 (11),1219-1229, 2016.

Shojaie, S., Ermini, L., Ackerley, C., Wang, J., Chin, S., Yeganeh, B., Bilodeau,M., Sambi, M., Rogers, I., Rossant, J., Bear, CE., Post, M. Acellular Lung Scaffolds Direct Differentiation of Endoderm to Functional Airway Epithelial Cells: Requirement of Matrix-bound HS Proteoglycans. Stem Cell Reports 4, 1-12, 2015

Fox, E., Wang, J., Tseu, I., Ackerley, C., Bilodeau, M., Post, M. Three-dimensional culture and FGF signaling drive differentiation of murine pluripotent cells to distal lung epithelial cells. Stem Cells Dev 24: 21-35, 2015.

Congenital Diaphragmatic Hernia

Pereira-Terra, P., Deprest, J.A., Kholdebarin, R., DeKoninck, P., Boerema-De Munck, A.A., Wang, J., Zhu, F., Rottier, R.J., Iwasiow, B.M., Correia-Pinto, J., Tibboel, D., Post, M., Keijzer, R. Unique Tracheal Fluid MicroRNA Signature Predicts Response to FETO in Patients with Congenital Diaphragmatic Hernia. Ann Surg 262:1130-40, 2015.

van Loenhout, R.B, Tseu, I., Fox, E.K., Huang, Z., Tibboel, D., Post, M., Keijzer, R. The pulmonary mesenchymal tissue layer is defective in an in vitro recombinant model of nitrofen-induced lung hypoplasia. Am J Pathol 180(1):48-60, 2012.

Keijzer, R., Liu, J., Deimling, J., Tibboel, D., Post, M. Dual-hit hypothesis explains pulmonary hypoplasia in the nitrofen model of congenital diaphragmatic hernia. Am J Pathol 156, 1299-1306, 2000.

Placenta

Melland-Smith M, Ermini L, Chauvin S, Craig-Barnes H, Tagliaferro A, Todros T, Post M, Caniggia I. Disruption of Sphingolipid Metabolism Augments Ceramide-Induced Placental Autophagy in Preeclampsia. Autophagy 11: 653-69, 2015.

Soleymanlou, N., Jurisica, I., Zamudio, S., Post, M., Caniggia, I. Molecular Evidence of Placental Hypoxia in Preeclampsia. J Clin Endocrin & Metab 90(7): 4299-308, 2005.

Caniggia, I., Mostachfi, H., Winter, J., Gassman, M, Lye, S., Kuliszewski, M, Post, M. Hypoxia inducible factor-1α mediates the biological effects of oxygen on human trophoblast differentiation via TGFß3. J Clin Invest 105, 577-587, 2000.