Publications

Recent publications

Youssef M & Park J. LONRF2 is a gatekeeper against protein aggregation in aging neurons. Nature Aging (2023) DOI: 10.1038/s43587-023-00457-3. Epub ahead of print. PMID: 37474790.

Maksimovic K, Youssef M, You J, Sung H.K., Park J. Evidence of Metabolic Dysfunction in Amyotrophic Lateral Sclerosis (ALS) Patients and Animal Models. Biomolecules (2023) 13(5):863. DOI: 10.3390/biom13050863. PMID: 37238732

van Bruggen R*, Maksimovic K*, You J, Tran DD, Lee HJ, Khan M, Kao CS, Kim JR, Cho W, Chen XXL, Park J. MATR3 F115C knock-in mice do not exhibit motor defects or neuropathological features of ALS. Biochem Biophys Res Commun. 2021 Jun 25;568:48-54. PubMed PMID: 34182213. DOI: 1016/j.bbrc.2021.06.052 (*: co-first authors)

Kao CS*, van Bruggen R*, Kim JR*, Chen XXL*, Chan C, Lee J, Cho WI, Zhao M, Arndt C, Maksimovic K, Khan M, Tan Q, Wilson MD, Park J. Selective neuronal degeneration in MATR3 S85C knock-in mouse model of early-stage ALS. Nat Commun. 2020 Oct 20;11(1):5304. PubMed Central PMCID: PMC7576598. DOI: 1038/s41467-020-18949-w (*: co-first authors)

Chosen as an ‘Editor’s highlight’ article – Nature communications

Zhao M*, Kao CS*, Arndt C, Tran DD, Cho WI, Maksimovic K, Chen XXL, Khan M, Zhu H, Qiao J, Peng K, Hong J, Xu J, Kim D, Kim JR, Lee J, van Bruggen R, Yoon WH, Park J. Knockdown of genes involved in axonal transport enhances the toxicity of human neuromuscular disease-linked MATR3 mutations in Drosophila. FEBS Lett. 2020 Sep;594(17):2800-2818. PubMed PMID: 32515490. DOI: 1002/1873-3468.13858 (*: co-first authors)

Featured as an ‘Editor’s choice’ article – FEBS Letters

Zhao M*, Kim JR*, van Bruggen R, Park J. RNA-Binding Proteins in Amyotrophic Lateral Sclerosis. Mol Cells. 2018 Sep 30;41(9):818-829. PubMed Central PMCID: PMC6182225. DOI: 14348/molcells.2018.0243 (*: co-first authors)

Selected publications by Jeehye Park in previous labs

Tan, Q.*, Yalamanchili, H.K.*, Park, J.*, De Maio, A., Lu, H., Wan, Y., White, J.J., Bondar, V.V., Sayegh, L.S., Liu, X., Gao, Y., Sillitoe, R.V., Orr, H.T., Liu, Z. & Zoghbi, H.Y. Extensive cryptic splicing upon loss of RBM17 and TDP43 in neurodegenerative models. Hum. Molec. Genet. (2016) 25(23):5083-93. PMID: 28007900. DOI: 10.1093/hmg/ddw337 (*: co-first authors) (cover)

Park, J.*, Al-Ramahi, I.*, Tan, Q., Mollema, N., Diaz-Garcia, J. R., Gallego-Flores, T., Lu, H.-C., Lagalwar, S., Duvick, L., Kang, H., Lee, Y., Jafar-Nejad, P., Sayegh, L. S., Richman, R., Liu, X., Gao, Y., Shaw, C. A., Arthur, J. C., Orr, H. T., Westbrook, T. F., Botas, J. & Zoghbi, H. Y. RAS/MAPK/MSK1 pathway modulates Ataxin-1 protein levels and toxicity in SCA1. Nature (2013) 498(7454):325-31. PMID: 23719381. DOI: 10.1038/nature12204 (*: co-first authors)

Park, J., Kim, Y. & Chung, J. Mitochondrial dysfunction and Parkinson’s disease genes: insights from Drosophila. Dis. Model Mech. (2009) 2(7-8):336-40. PMID: 19553694. DOI:10.1242/dmm.003178 (Review paper)

Kim, Y.*, Park, J.*, Kim, S.*, Song, S., Kwon, S.K., Lee, S.H., Kitada, T., Kim, J.M. & Chung, J. PINK1 controls mitochondrial localization of Parkin through direct phosphorylation. Biochem. Biophys. Res. Commun. (2008) 377(3):975-80. PMID: 18957282. DOI: 10.1016/j.bbrc.2008.10.104 (*: co-first authors)

Park, J.*, Lee, S. B.*, Lee, S., Kim, Y., Song, S., Kim, S., Bae, E., Kim, J., Shong, M., Kim, J. & Chung, J. Mitochondrial dysfunction in Drosophila PINK1 mutants is complemented by parkin. Nature (2006) 441(7097):1157-61. PMID: 16672980. DOI: 10.1038/nature04788 (*: co-first authors)