Publications

Highlighted Publications

McGillis L, Bronte-Tinkew, D, Dang F, McGillis L, Capurro M, Greenfield L, Riccuito A, Lozano-Ruf A, Siddiqui I, Hsieh A, Church P, Walters T, Roth D, Griffiths A, Philpott D, Jones NL. Vitamin D deficiency enhances expression of autophagy-regulating miR-142-3p in mouse and inflamed IBD patient intestinal tissues. American Journal of Physiology GI. 2021 Aug 1;321(2): G171-G184.
Capurro MI, Prashar A, Jones NL. MCOLN1/TRPML1 inhibition – a novel strategy used by Helicobacter pylori to escape autophagic killing and antibiotic eradication therapy in vivo. Autophagy. 2020 Jan;16(1):169-170.
Capurro M, Greenfield LK, Abdullah M, Wong H, Zhong XZ, Wilms KJD, Bertaux-Skeirik N, Chakrabarti J, O’Brien C, Dong XP, Robinson L, Philpott DJ, Zavros Y, Helmrath M, Jones NL. (2019). VacA generates a protective intracellular reservoir for Helicobacter pylori which is eliminated by activation of the lysosomal calcium channel TRPML1. Nature Microbiology. 4(8): 1411-1423.
Abdullah M, Greenfield L, Bronte-Tinkew D, Capurro M, Rizzuti D, Jones NL. (2019). VacA promotes CagA accumulation in gastric epithelial cells during Helicobacter pylori infection. Scientific Reports. 9(1): 38
Sibony M, Abdullah M, Greenfield L, Raju D, Wu T, Rodrigues D, Galindo-Mata E, Mascarenhas H, Philpott D, Silverberg M, Jones NL. Microbial disruption of autophagy alters expression of the RISC component AGO2, a critical regulator of the miRNA silencing pathway. Journal of Inflammatory Bowel Diseases Dec 2015: 21 (12): pp 2778-2786. PMID: 26332312
Rizzuti D, Ang M, Sokollik C, Wu T, Fattouh R, Reardon C, Schindler C, Jones NL. Helicobacter pylori inhibits dendritic cell maturation via interleukin-10 mediated activation of the signal transducer and activator of transcription 3 (STAT3) pathway. Journal of Innate Immunity Feb 2015: 7 (2): pp 199-211. PMID: 25412627
Raju D, Hussey S, Ang M, Terebiznik MR, Sibony M, Galindo-Mata E, Gupta V, Blanke SR, Delgado A, Romero-Gallo J, Ramjeet MS, Mascarenhas H, Peek RM, Correa P, Streutker C, Hold G, Kunstmann E, Yoshimori T, Silverberg MS, Girardin SE, Philpott DJ, El Omar E, Jones NL. Vacuolating cytotoxin and variants in Atg16L1 that disrupt autophagy promote Helicobacter pylori infection in humans. Gastroenterology 2012: 142 (5): pp 1160-1171.
Travasso LH, Carneiro LAM, Hussey S, Yuan L, Magalhaes JG, Le Bourhis L, Ramjeet M, Boneca IG, Allaoui A, Jones NL, Girardin SE and Philpott DJ. Nod1 and Nod2 direct autophagy by recruiting ATG16L1 to the plasma membrane at the site of bacterial entry. Nature Immunology. 2010: 11 (1): pp 55-62. (Accompanying editorial in Nature Medicine 2010: 16 (1): pp 28-30).

2021

McGillis L, Bronte-Tinkew, D, Dang F, McGillis L, Capurro M, Greenfield L, Riccuito A, Lozano-Ruf A, Siddiqui I, Hsieh A, Church P, Walters T, Roth D, Griffiths A, Philpott D, Jones NL. Vitamin D deficiency enhances expression of autophagy-regulating miR-142-3p in mouse and inflamed IBD patient intestinal tissues. American Journal of Physiology GI. 2021 Aug 1;321(2): G171-G184.
Macarthur C, Walsh C, Buchanan F, Karoly A, Pires L, McCreath G, Jones NL. Development of the Patient-Oriented Research Curriculum in Child Health (PORCCH). Submitted to Research Involvement and Engagement. Accepted
Prashar A, Capurro MI, Jones NL. (2021). Under the radar: Strategies used by Helicobacter pylori to evade host responses. Annual Reviews in Physiology. Accepted
Jaehoon C, Prashar A, Jones N, Moss, SF. (2021). Helicobacter pylori Infection. Gastroenterology Clinics of NA. 50(2): 1131.

2020

Seo JH, Bortolin K, Jones NL. (2020). Review: Helicobacter pylori infection in Children. Helicobacter. 25(S1): e12742
Capurro MI, Prashar A, Jones NL. MCOLN1/TRPML1 inhibition – a novel strategy used by Helicobacter pylori to escape autophagic killing and antibiotic eradication therapy in vivo. Autophagy. 2020 Jan;16(1):169-170

2019

Capurro M, Greenfield LK, Abdullah M, Wong H, Zhong XZ, Wilms KJD, Bertaux-Skeirik N, Chakrabarti J, O’Brien C, Dong XP, Robinson L, Philpott DJ, Zavros Y, Helmrath M, Jones NL. (2019). VacA generates a protective intracellular reservoir for Helicobacter pylori which is eliminated by activation of the lysosomal calcium channel TRPML1. Nature Microbiology. 4(8): 1411-1423.
Abdullah M, Greenfield L, Bronte-Tinkew D, Capurro M, Rizzuti D, Jones NL. (2019). VacA promotes CagA accumulation in gastric epithelial cells during Helicobacter pylori infection. Scientific Reports. 9(1): 38
Goldaracena N, Echeverri J, Kehar M, DeAngelis M, Jones N, Ling S, Kamath BM, Avitzur Y, Ng VL, Cattral MS, Grant DR, Ghanekar A. (2019). Pediatric Living Donor Liver Transplantation with Large-for-Size Left Lateral Segment Grafts. Am J Transplant. 20(2):504-512
Benchimol E, Jones NL, Muise AM, Sherman PM. (2019). 2019 Harry Shwachman Award: Dr. Anne M. Griffiths, MD, FRCPC. J Pediatric Gastroenterology Nutrition.
Kehar M, Parekh R.S, Stunguris J, De Angelis M, Van Roestel K, Ghanekar A, Cattral M, Fecteau A, Ling S, Kamath BM, Jones N, Avitzur Y, Grant D, NG VL. Superior outcomes and reduced wait times in pediatric recipients of living donor liver transplantation. Transplantation Direct Feb 2019: 5 (3): pp e430.