Our gastrointestinal tract plays an important role both in maintaining health and wellbeing. However, changes within our gastrointestinal tract or the bacteria housed in our gut can trigger disease. The Jones lab team is interested in understanding the pathogenesis of chronic intestinal disorders with the hopes of improving health and treating or preventing disease.

Our laboratory focuses on two main areas:

  1. Identifying mechanisms by which chronic infection with Helicobacter pylori causes inflammation and gastric cancer.
  2. Delineating the interplay between microbes, host genetics and the environment in inflammatory bowel disease.

Our translational research program employs cell culture, organoids, animal models and patient samples to answer our research questions.