Abdelilah-Seyfried S., Tournier-Lasserve E., and Brent Derry W. Blocking signalopathic events to treat Cerebral Cavernous Malformations. Trends in Molecular Medicine. 2020.

Popiel E, Derry WB. Affinity Purification and Preparation of Peptides for Mass Spectrometry from C. elegans. Methods in Molecular Biology. 2020;2152:479-485.

Popiel E, Derry WB. Generation and Analysis of CCM Phenotypes in C. elegans. Methods in Molecular Biology. 2020;2152:191-205.

Subramanian A, Hall M, Hou H, Mufteev M, Yu B, Yuki KE, Nishimura H, Sathaseevan A, Lant B, Zhai B, Ellis J, Wilson MD, Daugaard M, Derry WB. Alternative polyadenylation is a determinant of oncogenic Ras function. bioRxiv 2020.06.08.140145.

Tran, A.T, Chapman, E.M., Flamand, M.N., Yu, B., Krempel, S.J., Duchaine, T.F., Eroglu, M., & Derry, W.B. MiR-35 buffers apoptosis thresholds in the C. elegans germline by antagonizing both MAPK and core apoptosis pathways. (2019)  Cell Death & Differentiation,  published online.

Chapman, E.M., Lant, B., Ohashi, Y., Yu, B., Schertzberg, M., Go, C., Dogra, D., Koskimäki, J., Girard, R., Li, Y., Fraser, A.G., Awad, I.,A., Abdelilah-Seyfried, S., Gingras, A.C., & Derry, W.B. A Conserved CCM Complex Promotes Apoptosis Non-autonomously by Regulating Zinc Homeostasis. (2019) Nature Communications, 10 (1): 1791

Koskimäki J, Girard R, Li Y, Saadat L, Zeineddine HA, Lightle R, Moore T, Lyne S, Avner K, Shenkar R, Cao Y, Shi C, Polster SP, Zhang D, Carrión-Penagos J, Romanos S, Fonseca G, Lopez-Ramirez MA, Chapman EM, Popiel E, Tang AT, Akers A, Faber P, Andrade J, Ginsberg M, Derry WB, Kahn ML, Marchuk DA, Awad IA. Comprehensive transcriptome analysis of cerebral cavernous malformation across multiple species and genotypes.  (2019) JCI Insight, published online.

Lant, B., Pal, S., Chapman, E.M., Yu, B., Witvliet, D., Choi, S., Zhao, L., Albiges-Rizo, C., Faurobert, E. & Derry, W.B. Interrogating the ccm-3 gene network. (2018) Cell Reports, 24(11), 2857-2868

Otten, C., Knox, J., Boulday, G., Eymery, M., Haniszewski, M., Neuenschwander, M., Radetzki, S., Vogt, I., Hähn, K., De Luca, C., Cardoso, C., Hamad, S., Gil, C.I., Roy, P., Albiges-Rizo, C., Faurobert, E., von Kries, J., Campillos, M., Tournier-Lasserve, E., Derry, W.B., Seyfried, S. Systematic pharmacological suppression uncovers novel molecular pathways involved in cerebral cavernous malformations. (2018) EMBO Molecular Medicine, published online.

Verster, A.J., Styles, E.B., Mateo, A., Derry, W.B., Andrews, B.J., Fraser, A. Taxonomically restricted genes with essential functions frequently play roles in chromosome segregation in Caenorhabditis elegans and Saccharomyces cerevisiae(2017) G3 (Bethesda). 7(10): 3337-3347.

Pal, S., Lant, B., Yu, B., Tian, R., Tong, J., Krieger, J.R., Moran, M.F., Gingras, A.C., & Derry, W. B. CCM-3 Promotes C. elegans germline development by regulating vesicle trafficking cytokinesis and polarity. (2017) Current Biology. 27(6): 868-876.

Mateo, A.R. & Derry, W. B. CEP-1 is pro-choice for reproductive health in C. elegans. (2016) Invited editorial, Cell Cycle. 15(21): 2843-2844.

Derry, W.B. Chewing the fat about death with the neighbours. (2016) Invited editorial, Cell Death and Differentiation. 23(7): 1097-1098.

Eroglu, M. & Derry, W.B. (2016) Your neighbours matter – non-autonomous control of apoptosis in development and disease. Cell Death and Differentiation. 23(7): 1110-1118.

Mateo, A.R, Kessler, Z., Jolliffe, A.K., McGovern, O., Yu, B., Nicolucci, A., Yanowitz, J.L. & Derry, W.B. (2016) The p53-like protein CEP-1 is required for meiotic fidelity in C. elegans. Current Biology. 26(9): 1148-1158.

Phanse, S., Wan, C., Borgeson, B., Tu, F., Drew, K., Clark, G., Xiong, X., Kagan, O., Kwan, J., Berzginov, A., Chessman, K., Pal, S., Cromar, G., Papoulas, O., Ni, Z., Boutz, D.R., Stoilova, S., Havugimana, P.C., Guo, X., Malty, R.H., Sarov, M., Greenblatt, J., Babu, M., Derry, W.B., Tillier, E., Wallingford, J.B., Parkinson, J., Marcotte, E.M. & Emili. A. (2015) Proteome-wide dataset supporting the study of ancient metazoan macromolecular complexes. Data in Brief. 6: 715-721.

Wan C, Borgeson B, Phanse S, Tu F, Drew K, Clark G, Xiong X, Kagan O, Kwan J, Bezginov A, Chessman K, Pal S, Cromar G, Papoulas O, Ni Z, Boutz DR, Stoilova S, Havugimana PC, Guo X, Malty RH, Sarov M, Greenblatt J, Babu M, Derry WB, R Tillier E, Wallingford JB, Parkinson J, Marcotte EM, Emili A. (2015) Panorama of ancient metazoan macromolecular complexes. Nature. 525(7569): 339-344.

Lant B, Yu B, Goudreault M, Holmyard D, Knight JD, Xu P, Zhao L, Chin K, Wallace E, Zhen M, Gingras AC, Derry WB. (2015) CCM-3/STRIPAK promotes seamless tube extension through endocytic recycling. Nature Communications. 6: 6449.

Lant, B. & Derry, W.B. (2014). Immunostaining for markers of apoptosis in the Caenorhabditis elegans germline. Cold Spring Harbor Protocols. 2014(5) pii: pdb.prot080242.

Lant, B. & Derry, W.B. (2014). Analysis of apoptosis in Caenorhabditis elegans. Cold Spring Harbor Protocols. 2014(5): pii: pdb.top070458.

Lant, B. & Derry, W.B. (2014). High-throughput RNAi screening for germline apoptosis genes in Caenorhabditis elegans. Cold Spring Harbor Protocols. 2014(4): 428-434.

Lant, B. & Derry, W.B. (2014). Fluorescent visualization of germline apoptosis in living Caenorhabditis elegans. Cold Spring Harbor Protocols. 2014(4): 420-427.

Lant, B. & Derry, W.B. (2014). Visualizing apoptosis in embryos and the germline of Caenorhabditis elegans. Cold Spring Harbor Protocols. 2014(3): 278-283. Cover Article

Lant, B. & Derry, W.B. (2014). Induction of germline apoptosis in Caenorhabditis elegans. Cold Spring Harbor Protocols. 2014(3): 271-277.

Baruah, A., Chang, H., Hall, M., Yuan, J., Gordon, S., Johnson, E., Shtessel, L.L., Yee, C., Hekimi, S., Derry, W.B., & Lee, S.S. (2014). CEP1, the Caenorhabditis elegans p53 homolog, mediates opposing longevity outcomes in mitochondrial electron transport chain mutants. PLoS Genetics. 10(2): e1004097.

Lant, B. & Derry, W.B. (2013). Methods for detection and analysis of apoptosis signalling in the C. elegans germline. Methods. 61(2): 174-182.

Leprivier, G., Remke, M., Dubuc, A., Rotblat, B., Kool, M., Agnihotr, S., El-Naggar, A., Yu, B., Mateo, A.R.F., Somasekharan, S., Tognon, C.E., Mathers, J., Thomas, R., Barokas, A., Bowden, M., Smith, S., Wu, X., Korshunov, A., Hielscher, T., Northcott, P.A., McCabe, M.G., Delattre, O., Gleave, M.E., Jan, E., Proud, C.G., Pfister, SM., Derry, W.B., Taylor, M.D., and Sorensen, P.H.B. (2013). The eEF2 kinase confers resistance to nutrient deprivation by blocking translation elongation. Cell. 153(5): 1064-1079.

Perrin, A.J., Gunda, M., Yu, B., Yen, K., Ito, S., Forster, S., Young, J., Tissenbaum, H.A. & Derry, W.B. (2013). Noncanonical control of C. elegans germline apoptosis by the insulin/IGF-1 and Ras/MAPK signaling pathways. Cell Death and Differentiation. 20(1): 97-107.

Jolliffe, A.K. & Derry, W.B. (2013). The p53 signaling network in mammals and worms. Briefings in Functional Genomics. 12(2): 129-141.

Ceccarelli, D.F., Laister, R.C., Mulligan, V.K., Kean, M.J., Goudreault, M., Scott, I.C., Derry, W.B., Chakrabartty, A., Gingras, A.C. & Sicheri, F. (2011). CCM3/PDCD10 heterodimerizes with germinal center kinase III (GCKIII) proteins using a mechanism analogous to CCM3 homodimerization. Journal of Biological Chemistry. 286(28): 25056-25064.

Kean,M.J., Ceccarelli, D., Goudreault, M., Sanches, M., Tate, S., Larsen, B., Gibson, L.C., Derry, W.B., Scott, I.C., Pelletier, L., Baillie, G., Sicheri, F. & Gingras, A.C. (2011). Structure-function analysis of core STRIPAK: a signalling complex implicated in golgi polarization. Journal of Biological Chemistry. 286(28): 25065-25075.

Ross, A.J., Li, M., Yu, B., Gao, M.X. & Derry, W.B. (2011). The EEL-1 ubiquitin ligase promotes DNA damage-induced germ cell apoptosis in C. elegans. Cell Death and Differentiation. 18(7): 1140-1149.

Ito, S., Greiss, S., Gartner, A. & Derry, W.B. (2010). Cell-nonautonomous regulation of C. elegans germ cell death by kri-1. Current Biology. 20(4): 333-338.

Gao, X. Liao, E., Yu, B., Wang, Y., Zhen, M. & Derry, W.B. (2008). The SCFFSN-1 ubiquitin ligase controls CEP-1/p53-dependent apoptosis in Caenorhabditis elegans. Cell Death and Differentiation. 15(6): 1054-1062.

Taylor, R.C., Brumatti, G., Ito, S., Hengartner, M.O., Derry, W.B. & Martin SJ. (2007). Establishing a blueprint for CED-3-dependent killing through identification of multiple substrates for this protease. Journal of Biological Chemistry. 282(20): 15011-15021.

Derry, W.B., Bierings, R., van Iersel, M. , Satkunendran, T., Reinke, V. & Rothman, J.H. (2007). Regulation of developmental timing and germ cell proliferation in C. elegans by the p53 gene network. Cell Death and Differentiation. 14(4): 662-670.

Quevedo, C., Kaplan, D.R. & Derry, W.B. (2007). AKT-1 regulates DNA-damage induced germline apoptosis in C. elegans. Current Biology. 17(3): 286-292.

Huyen, Y., Stavridi, E.S., Derry, W.B., Jeffrey, P., Rothman, J.H., Pavletich, N.P. & Halazonetis, T.D. (2004). Structural differences in the DNA binding domains of human p53 and its evolutionary ancestor C. elegans CEP-1. Structure. 12(7): 1237-1243.

Dumontet, C., Jaffrezou, J.P., Tsuchiya, E., Duran, G.E., Chen, G., Derry, W.B., Wilson, L., Jordan, M.A., Sikic, B.I. (2004). Resistance to microtubule-targeted cytotoxins in a K562 leukemia cell variant associated with altered tubulin expression and polymerization. Bulletin du Cancer. 91(5): E81-E112.

 

Fukuyama, M, Gendreau, S.B., Derry, W.B. & Rothman, J.H. (2003). Essential embryonic roles of the CKI-1 cyclin-dependent kinase inhibitor in cell-cycle exit and morphogenesis in C. elegans. Developmental Biology. 260(1): 273-286.

Derry, W.B., Putzke, A.P. & Rothman, J.H. (2001). Caenorhabditis elegans p53: Role in apoptosis, meiosis, and stress resistance. Science. 294(5542): 591-594.

Sugimoto, A, Kusano, A., Hozak, R.R., Derry, W.B., Zhu, J. & Rothman, J.H. (2001). Many genomic regions are required for normal embryonic programmed cell death in Caenorhabditis elegans. Genetics. 158(1): 237-252.