Brumell Lab

Exploring the interface between pathogens and human cell biology.

The Brumell Lab

Exploring the interface between pathogens and human cell biology.

Our research

The Brumell Lab is working to understand how intracellular pathogens interact with their hosts to subvert cellular immunity and adapt host processes to their advantage.

Although we primarily focus on Salmonella and Listeria, we have been recently expanding the common themes identified in these bacterial models to other pathogens including parasites such as Trypanosoma. By studying host-pathogen interactions, we are able to discover unique aspects of cell biology such as membrane dynamics, intracellular trafficking and autophagy.

Brumell lab photo on the stairs in the Research Institute.
Images acquired
Image of the Hospital for Sick Children's Research Institute.

Research environment

The Brumell Lab is located in the heart of downtown Toronto at The Hospital for Sick Children (SickKids) Research Institute (RI) – one of the largest paediatric research institutes in the world. Under the RI, we have access to:

  • World-class core facilities to support our research
  • State-of-the-art light and electron microscopes
  • An in-house animal facility that provides access and care for our model organisms

We are a part of the Cell Biology program at SickKids, which features weekly journal clubs and seminar series with international guest speakers.

Current funding

Canadian Institutes of Health Research logo
Canada Foundation for Innovation Logo
Emerging and Pandemic Infections Consortium Logo