Selected publications from the Zani lab

Anti-inflammatory effects of antenatal administration of stem cell derived extracellular vesicles in the brain of rat fetuses with congenital diaphragmatic hernia
Blundell M, Doktor F, Figueira RL, Khalaj K, Biouss G, Antounians L, Zani A.
Pediatric Surgery International. 2023 Nov 13.


Congenital diaphragmatic hernia: exploring the intersection of personal experience and research
Zani A, Puri P.
Pediatric Research. 2023 May 31.


Beyond the diaphragm and the lung: a multisystem approach to understanding congenital diaphragmatic hernia
Antounians L, Zani A.
Pediatric Surgery International. 2023 May 9.


Congenital lung malformations: Dysregulated lung developmental processes and altered signaling pathways
Doktor F, Antounians L, Lacher M, Zani A.
Seminars in Pediatric Surgery. 2022 November 16.


Treatment with Amniotic Fluid Stem Cell Extracellular Vesicles Promotes Fetal Lung Branching and Cell Differentiation at Canalicular and Saccular Stages in Experimental Pulmonary Hypoplasia Secondary to Congenital Diaphragmatic Hernia
Khalaj K, Figueira RL, Antounians L, Gandhi S, Wales M, Montalva L, Biouss G, Zani A.
Stem Cells Translational Medicine. 2022 September 14.


Autophagy Is Impaired in Fetal Hypoplastic Lungs and Rescued by Administration of Amniotic Fluid Stem Cell Extracellular Vesicles
Khalaj K, Antounians L, Figueira RL, Post M, Zani A.
American Journal of Respiratory and Critical Care Medicine. 2022 August 15.


Seasonal Variation Of Congenital Diaphragmatic Hernia: A Review Of The Literature And Database Report From USA And Canada
Doktor F, Antounians L, Miller J, Harb M, Meats T, Bercovitch R, Ireland D, Zani A.
European Journal of Pediatric Surgery. 2022 July 20.


Congenital Diaphragmetic Hernia
Zani A, Chung WK, Deprest J, Harting MT, Jancelewicz T, Kunisaki SM, Patel N, Antounians L, Puligandla PS, Keijzer R.
Nature Reviews Disease Primers. 2022 June 1.


The Role of Exosomes in the Treatment, Prevention, Diagnosis, and Pathogenesis of COVID-19.
Zani-Ruttenstock E, Antounians L, Khalaj K, Figueira RL, Zani A.
European Journal of Paediatric Surgery. 2021 June 23.


Fetal lung underdevelopment is rescued by administration of amniotic fluid stem cell extracellular vesicles in rodents.
Antounians L, Catania VD, Montalva L, Liu BD, Hou H, Chan C, Matei AC, Tzanetakis A, Li B, Figueira RL, da Costa KM, Wong AP, Mitchell R, David AL, Patel K, De Coppi P, Sbragia L, Wilson MD, Rossant J, Zani A.
Science Translational Medicine. 2021 Apr 21;13(590):eaax5941.


Systematic review of extracellular vesicle-based treatments for lung injury: are EVs a potential therapy for COVID-19?
Khalaj K, Figueira RL, Antounians L, Lauriti G, Zani A.
Journal of Extracellular Vesicles. 2020 Aug 6;9(1):1795365.


The Regenerative Potential of Amniotic Fluid Stem Cell Extracellular Vesicles: Lessons Learned by Comparing Different Isolation Techniques.
Antounians L, Tzanetakis A, Pellerito O, Catania VD, Sulistyo A, Montalva L, McVey MJ, Zani A.
Scientific Reports. 2019 Feb 12;9(1):1837.


Congenital Diaphragmatic Hernia: State of the Art in Translating Experimental Research to the Bedside.
Antounians L, Figueira RL, Sbragia L, Zani A.
European Journal of Pediatric Surgery. 2019 Aug;29(4):317-327.