photo of William Trimble, Senior Scientist

Bill Trimble received his PhD in 1987 from the University of Toronto where he worked in the laboratory of Dr. Nobumichi Hozumi studying the mechanisms responsible for cellular transformation by the ras oncogene.  He then went on to do postdoctoral work with Dr. Richard Scheller at Stanford University where he discovered the VAMP protein, the first member of the family of proteins now known as SNAREs that are responsible for the fusion of membranes in virtually all cellular contexts.  In 1990 he moved back to the University of Toronto and in 1996 to the Hospital for Sick Children where he is a Senior Scientist and Head of the Cell Biology Program.

His research focuses on the basic mechanisms controlling a variety of cellular processes, such as membrane transport, lipid metabolism and cell division, and how these go awry in diseases such as atherosclerosis and cancer.


Awards & Distinctions

2006 — Fellow of the Royal Society of Canada
2005-2019 — Canada Research Chair in Molecular Cell Biology (Tier 1)
2000-2005 — CIHR Investigator Award
1987-1990 — MRC Centennial Fellow


Courses Taught

BCH 2024H Subcellular Social Networks: Inter-Organelle Contact sites
BCH473Y Advanced Research Project in Biochemistry
BCH444H Protein Trafficking in the Secretory and Endocytic Pathways

Extra-Departmental Courses

PSL450H Mechanisms of Neural and Endocrinal Secretion