Sazia Sharmin – Postdoctoral Fellow, 2017-2018
Sazia received her PhD from Kumamoto University, Japan with Dr. Ryuichi Nishinakamura. She studied renal development. Sazia established a protocol to generate glomeruli from patient derived induced pluripotent stem cells and developed a transplantation method to generate vascularized glomeruli. In the Ellis lab, Sazia worked with patient derived induced pluripotent stem cells (Rett syndrome and ASD) to generate peripheral sensory neuron that can be a useful model system for drug screening to treat ASD and Rett syndrome patients. She was funded by a Restracomp Graduate Scholarship.
Selected Publications:
Mulder J., S. Sharmin, T. Chow, D.C. Rodrigues, M. Hildebrandt, R. D’Cruz, I. Rogers, J. Ellis and N.D. Rosenblum. 2020. Generation of Kidney Organoid Tissue from Infant- and Pediatric-derived Urinary Induced Pluripotent Stem Cells. Pediatric Research 87:647-55.
Nishinakamura R, Sharmin S, Taguchi A. (2017) Induction of nephron progenitors and glomeruli from human pluripotent stem cells. Pediatr Nephrol. ;32(2):195-200.
Sharmin S*, Taguchi A*, Kaku Y, Yoshimura Y, Ohmori T, Sakuma T, Mukoyama M, Yamamoto T, Kurihara H, Nishinakamura R. (2016). Human Induced Pluripotent Stem Cell-Derived Podocytes Mature into Vascularized Glomeruli upon Experimental Transplantation. Journal of the American Society of Nephrology: JASN. 27(6): 1778-91.
Taguchi A, Kaku Y, Ohmori T, Sharmin S, Ogawa M, Sasaki H, Nishinakamura R. (2014). Redefining the in vivo origin of metanephric nephron progenitors enables generation of complex kidney structures from pluripotent stem cells. Cell Stem Cell. 14(1): 53-67.
Reza KA*, Sharmin S*, Moosa MM, Mahmood N, Ghosh A, Begun RA, Khan H. (2013). Identification and molecular characterization of a receptor-like protein kinase gene from Corchorus capsularis. Turkish Journal of Biology. 37: 11-17.
Sakaguchi M, Sharmin S, Taguchi A, Ohmori T, Fujimura S, Abe T, Kiyonari H, Komatsu Y, Mishina Y, Asashima M, Araki E, Nishinakamura R. (2013). The phosphatase Dullard negatively regulates BMP signalling and is essential for nephron maintenance after birth. Nature Communications. 4: 1398.
Sharmin S*, Azam MS*, IslamMS*, Sajib AA, Mahmood N, Hasan AMM, Ahmed R, Sultana K, Khan, H. (2012). Xyloglucan endotransglycosylase/ hydrolase genes from a susceptible and resistant jute species show opposite expression pattern following Macrophomina phaseolina infection. Communicative & Integrative Biology. 5(6): 598-606.
Sharmin S*, Moosa MM*, Islam MS, Kabir I, Akter A, Khan H. (2011). Identification of a novel dehydration responsive transcript from Tossa jute. Journal of Cell and Molecular Biology. 9(1): 21-29.
Ghosh A, Sharmin S, Islam S, Pahloan M., Islam S, Khan H. (2010). SSR markers linked to mite (Polyphagotarsonemus latus Banks) resistance in jute (Corchorus olitorius L.). Czech Journal of Genetics and Plant Breeding. 46(2): 64-74.
Alam MM*, Sharmin S*, Nabi Z, Mondal SI, Islam MS, Nayeem SB, Shoyaib M, Khan, H. (2010). A Putative Leucine-Rich Repeat Receptor-Like Kinase of Jute Involved in Stress Response. Plant Molecular Biology Reporter. 28(3): 392-402.