Joel Rubin arrived from Montreal with a B.Sc. from McGill University. For his M.Sc., he wrenched the HS3beta-globin transgene expression project from James’ hands (and took his bench too). He also contributed greatly to characterizing gene silencing induced by the eGFP reporter gene coding sequences.

Rubin was known for rabidly supporting the Montreal Canadiens and saying “Non?” when he meant yes.

Funded by an FCAR studentship.

Next position
Biologist, Merck Frosst, Kirkland QC

Selected Publications
Dalle B,* Rubin J*, Alkan O, Sukonnik T, Pasceri P, Yao S, Pawliuk R, Leboulch P, Ellis J. (2005) eGFP reporter genes silence LCRβ-globin transgene expression via CpG dinucleotides. *Equal first authors. Molecular Therapy. 11:591-599.

Rubin J, Pasceri P, Wu X, Leboulch P, Ellis J. (2000) Locus control region activity by 5’HS3 requires a functional interaction with beta-globin gene regulatory elements: expression of novel beta/gamma globin hybrid transgenes. Blood. 95: 3242-3249.