Matthew Hildebrandt – Postdoctoral Fellow, 2016-2019

Matthew Hildebrandt obtained his Ph.D. from the University of Alberta with Dr. Roseline Godbout. He studied the role of an RNA binding protein DEAD Box 1 in early mouse development. During his tenure on the project he was investigating post-transcriptional regulation that occurs maternal-to-zygotic transition.

Matthew studied post-transcriptionally in the Ellis lab and used induced pluripotent stem cells (iPSCs) as a model. Reprogrammed cells from patients or healthy donors can be differentiated into functioning neurons and he was interested in how genes were regulated at the level of mRNA during different stages of development as stem cells mature into their terminally differentiated cell types.

Next position: Matthew joined Stem Cell Technologies (Vancouver, BC) in July 2019.

 

Selected Publications:

Hildebrandt M.R.⁺, M.S. Reuter⁺, W. Wei, N. Tayebi, J. Liu, S. Sharmin, J. Mulder, S. Lesperance, P.M. Bauer, R. Mok, C. Kinnear, A. Piekna, A. Romm, J. Howe, P. Pasceri, G. Meng,M. Rozycki, D.C. Rodrigues, E.C. Martinez, M. Szego, J.C. Zuniga-Pflucker, M.K. Anderson, S.A. Prescott, N.D. Rosenblum, B.M. Kamath, S. Mital, S.W. Scherer* and J. Ellis*. 2019. Precision health resource of control iPSC lines for versatile multi-lineage differentiation. ⁺Co-first authors, *co-corresponding authors. Stem Cell Reports 13:1126-41.

 

Scientific contributions