About the study

Children with very severe cardiopulmonary failure in Canada are supported with Extracorporeal membrane oxygenation called ECMO. Surgeons connect children to an artificial lung and pump using large tubes in their neck vessels (artery and vein). When children no longer need this support, they are separated from ECMO. Historically, when separated, the neck vessels are tied off. Over the last decade, surgeons have started to repair the neck vessels instead.

We do not know if later in life, children are better off with or without repaired vessels. The goal of this study is to compare the outcomes between children who had the vessels tied off and those who had them repaired. We will evaluate health-related quality of life and cognitive function. As this has not been studied previously, the results will be used to guide future surgical practice.

Please stay tuned for more information coming in 2021.

What is ECMO?

ECMO stands for Extracorporeal Membrane Oxygenation. It is an advanced life support system, that provides heart and breathing support for people with severe heart or lung problems. ECMO uses a machine that acts as an artificial lung. Blood from the child will pass through the machine, which will remove carbon dioxide and add in oxygen before returning to the child.

Meet the study team

Lead investigator
Anne-Marie Guerguerian

Project Manager
Geraldine Goco

Co-Investigators
Osami Honjo
Katia Sinopoli

Knowledge Users
Renee Sananes
Mark Todd

CHEO
Ottawa, ON

Co-Investigators
Gyaandeo Maharajh
Sonny Dhanani
Mariella Vargas-Guiterrez

Co-Investigators
Ben Sivarajan
Laurance Lequier
Lindsay Ryerson

Interested in learning more about this study?