Publications

Featured publications

The Canadian laboratory initiative on pediatric reference intervals: A CALIPER white paper
Adeli K, Higgins V, Trajcevski K, White-Al Habeeb N
Crit Rev Clin Lab Sci, September 2017

Important considerations for interpreting biochemical tests in children
Adeli K, Higgins V, Trajcevski K, Palmert MR
BMJ, May 2018

Postprandial Dyslipidemia, Hyperinsulinemia, and Impaired Gut Peptides/Bile Acids in Adolescents With Obesity
Higgins V, Asgari S, Hamilton JK, Wolska A, Remaley AT, Hartmann B, Holst JJ, Adeli K
J Clin Endocrinol Metab, April 2020

Latest publications

LMS-based continuous reference percentiles for 14 laboratory parameters in the CALIPER cohort of healthy children and adolescents
Wilson SM, Bohn MK, Madsen A, Hundhausen T, Adeli K
Clin Chem Lab Med, Online ahead of print
Reply to Cartier et al. – Response to Calculated LDL-C: Time to move on?
Higgins V, White-Al Habeeb N, Adeli K
Can J Cardiol, Online ahead of print
Age-specific reference intervals for routine biochemical parameters in healthy neonates, infants, and young children in Iran
Abdollahian N, Ghazizadeh H, Mohammadi-Bajgiran M, Pashirzad M, Yaghooti Khorasani M, Bohn MK, Steele S, Roudi F, Kamel Khodabandeh A, Ghazi Zadeh S, Alami-Arani I, Badakhshan SN, Esmaily H, Ferns GA, Assaran-Darban R, Adeli K, Ghayour-Mobarhan M
J Cell Mol Med, January 2023
Definitions and major prerequisites of direct and indirect approaches for estimating reference limits
Haeckel R, Adeli K, Jones G, Sikaris K, Wosniok W
Clin Chem Lab Med, December 2022
Central role of laboratory medicine in public health and patient care
Olver P, Bohn MK, Adeli K
Clin Chem Lab Med, November 2022
Anti-Mullerian Hormone (AMH) reference values in the CALIPER cohort of healthy community children and adolescent
Ronn R, Bohn MK, Greenblatt EM, Hoffman B, Adeli K
Clin Biochem, October 2022
Determination of pediatric reference limits for 10 commonly measured autoantibodies
Sepiashvili L, Bohn MK, Hall A, Henderson T, Chen J, Dunst R, Adeli K
Clin Chem Lab Med, September 2022
Platelet-activating factor acetylhydrolase is a biomarker of severe anaphylaxis in children
Upton JEM, Hoang JA, Leon-Ponte M, Finkelstein Y, Du YJ, Adeli K, Eiwegger T, Grunebaum E, Vadas P
Allergy, September 2022
Canadian Society of Clinical Chemists Harmonized Clinical Laboratory Lipid Reporting Recommendations on the Basis of the 2021 Canadian Cardiovascular Society Lipid Guidelines
White-Al Habeeb NMA, Higgins V, Venner AA, Bailey D, Beriault DR, Collier C, Adeli K; Canadian Society of Clinical Chemists Working Group on Reference Interval Harmonization
Can J Cardiol, August 2022
Age and sex-specific reference intervals for pro-oxidant-antioxidant balance (PAB), anti-heat-shock protein 27 (Anti-hsp27) and routine laboratory tests in the middle-aged adult population
Ghazizadeh H, Bohn MK, Yaghooti-Khorasani M, Ghaffarian-Zirak R, Valizadeh M, Saberi-Karimian M, Safarian H, Khodabandeh AK, Zare-Feyzabadi R, Timar A, Mohammadi-Bajgiran M, Oladi MR, Gachpazan M, Rohban M, Esmaily H, Ferns GA, Adeli K, Ghayour-Mobarhan M
Biotechnol Appl Biochem, June 2022
β-Carotene Increases Activity of Cytochrome P450 2E1 during Ethanol Consumption
Sandoval C, Mella L, Godoy K, Adeli K, Farías J
Antioxidants (Basel), May 2022
Fujirebio Lumipulse SARS-CoV-2 antigen immunoassay: pooled analysis of diagnostic accuracy
Lippi G, Henry BM, Adeli K, Plebani M
Diagnosis (Berl), March 2022
Pediatric Reference Intervals for Point-of-Care Random Glucose in Healthy Children and Adolescents
Wilson S, Earle H, Bohn MK, Hall A, Adeli K
J Appl Lab Med, March 2022
Multi-Inflammatory Syndrome in Children: A View into Immune Pathogenesis from a Laboratory Perspective
Bohn MK, Yousef P, Steele S, Sepiashvili L, Adeli K
J Appl Lab Med, January 2022
Reference Standards for Newborn Screening of Metabolic Disorders by Tandem Mass Spectrometry: A Nationwide Study on Millions of Chinese Neonatal Populations
He F, Yang R, Huang X, Tian Y, Pei X, Bohn MK, Zou L, Wang Y, Li H, Wang T, Gu M, Jiang T, Chen X, Zou H, Wei H, Tian W, Tang T, Adeli K, Wang Z
Front Mol Biosci, December 2021
A Canadian Study of Cisplatin Metabolomics and Nephrotoxicity (ACCENT): A Clinical Research Protocol
Jain A, Huang R, Lee J, Jawa N, Lim YJ, Guron M, Abish S, Boutros PC, Brudno M, Carleton B, Cuvelier GDE, Gunaratnam L, Ho C, Adeli K, Kuruvilla S, Lajoie G, Liu G, Nathan PC, Rod Rassekh S, Rieder M, Waikar SS, Welch SA, Weir MA, Winquist E, Wishart DS, Zorzi AP, Blydt-Hansen T, Zappitelli M, Urquhart B
Can J Kidney Health, November 2021
Defining and Reporting on Critical Values in Genetics: A Laboratory Survey
Goh ES, Stavropoulos DJ, Adeli K
J Appl Lab Med, September 2021
Age- and sex-specific reference intervals for superoxide dismutase enzyme and several minerals in a healthy adult cohort
Ghazizadeh H, Kathryn Bohn M, Yaghooti-Khorasani M, Kamel Khodabandeh A, Zare-Feyzabadi R, Timar A, Mohammadi-Bajgiran M, Oladi MR, Rohban M, Esmaily H, Ferns GA, Adeli K, Ghayour-Mobarhan M.
J Clin Lab Anal, September 2021
Cardiac Biomarkers in Pediatrics: An Undervalued Resource
Bohn MK, Steele S, Hall A, Poonia J, Jung B, Adeli K
Clin Chem, July 2021
POCT: An Inherently Ideal Tool in Pediatric Laboratory Medicine
Wilson S, Bohn MK, Adeli K.
EJIFCC, June 2021
A Snapshot of Lipid Reporting Practices in Canadian Clinical Laboratories: An Urgent Need for Harmonization
Higgins V, Habeeb NW, Venner AA, Bailey D, Collier C, Adeli K; Canadian Society of Clinical Chemists (CSCC) Working Group on Reference Interval Harmonization
Can J Cardiol, June 2021
Pediatric reference interval verification for common biochemical assays on the Abbott Alinity system
Bohn MK, Wilson S, Hall A, Massamiri Y, Randell E, Adeli K
Clin Chem Lab Med, May 2021
Reference intervals for hemoglobin and mean corpuscular volume in an ethnically diverse community sample of Canadian children 2 to 36 months
Hamid JS, Atenafu EG, Borkhoff CM, Birken CS, Maguire JL, Bohn MK, Adeli K, Abdelhaleem M, Parkin PC
BMC Pediatr, May 2021
IFCC interim guidelines on rapid point-of-care antigen testing for SARS-CoV-2 detection in asymptomatic and symptomatic individuals
Bohn MK, Lippi G, Horvath AR, Erasmus R, Grimmler M, Gramegna M, Mancini N, Mueller R, Rawlinson WD, Menezes ME, Patru MM, Rota F, Sethi S, Singh K, Yuen KY, Wang CB, Adeli K; IFCC Taskforce on COVID-19
Clin Chem Lab Med, April 2021
Establishing hematological reference intervals in healthy adults: Ravansar non-communicable disease cohort study, Iran
Moradinazar M, Najafi F, Pasdar Y, Hamzeh B, Shakiba E, Bohn MK, Adeli K, Rahimi Z
Int J Lab Hematol, April 2021
Guidance for the design and reporting of studies evaluating the clinical performance of tests for present or past SARS-CoV-2 infection
Doust JA, Bell KJL, Leeflang MMG, Dinnes J, Lord SJ, Mallett S, van de Wijgert JHHM, Sandberg S, Adeli K, Deeks JJ, Bossuyt PM, Horvath AR
BMJ, March 2021
Normative Values of High-Sensitivity Cardiac Troponin T and N-Terminal pro-B-Type Natriuretic Peptide in Children and Adolescents: A Study from the CALIPER Cohort
Lam E, Higgins V, Zhang L, Chan MK, Bohn MK, Trajcevski K, Liu P, Adeli K, Nathan PC
J Appl Lab Med, March 2021

Normative serum lipid profiles in the Iranian adult population
Shabani N, Kamel Khodabandeh A, Bohn MK, Ghazizadeh H, Saberi-Karimian M, Ghafarian Zirak R, Emamian M, Haddadi Aval A, Fazli Y, Tayefi M, Esmaily H, Ferns GA, Rahnama G, Manavi N, Adeli K, Ghayour-Mobarhan M
Int J Clin Pract, February 2021
Pediatric evaluation of clinical specificity and sensitivity of SARS-CoV-2 IgG and IgM serology assays
Bohn MK, Hall A, Wilson S, Taher J, Sepiashvili L, Adeli K
Clin Chem Lab Med, January 2021
High fat-high fructose diet-induced changes in the gut microbiota associated with dyslipidemia in Syrian hamsters
Horne RG, Yu Y, Zhang R, Abdalqadir N, Rossi L, Surette M, Sherman PM, Adeli K
Nutrients, November 2020
Comprehensive laboratory reference intervals for routine biochemical markers and pro-oxidant-antioxidant balance (PAB) in male adults
Ghazizadeh H, Bohn MK, Zirak RG, Khodabandeh AK, Zare-Feyzabadi R, Saberi-Karimian M, Timar A, Jaberi N, Mohammadi-Bajgiran M, Sharifan P, Tayefi M, Silakhori S, Emamian M, Oladi MR, Esmaily H, Ferns GA, Adeli K, Ghayour-Mobarhan M
J Clin Lab Anal, November 2020

IFCC interim guidelines on biochemical/hematological monitoring of COVID-19 patients
Thompson S, Bohn MK, Mancini N, Loh TP, Wang CB, Grimmler M, Yuen KY, Mueller R, Koch D, Sethi S, Rawlinson WD, Clementi M, Erasmus R, Leportier M, Kwon GC, Menezes ME, Patru MM, Gramegna M, Singh K, Najjar O, Ferrari M, Lippi G, Adeli K, Horvath A and the IFCC Taskforce on COVID-19
Clin Chem Lab Med, October 2020
IFCC interim guidelines on serological testing of antibodies against SARS-CoV-2
Bohn MK, Loh TP, Wang CB, Mueller R, Koch D, Sethi S, Rawlinson WD, Clementi M, Erasmus R, Leportier M, Grimmler M, Yuen KY, Mancini N, Kwon GC, Menezes ME, Patru MM, Gramegna M, Singh K, Najjar O, Ferrari M, Horvath A, Lippi G, Adeli K and the IFCC Taskforce on COVID-19
Clin Chem Lab Med, October 2020

IFCC interim guidelines on molecular testing of SARS-CoV-2 infection
Bohn MK, Mancini N, Loh TP, Wang CB, Grimmler M, Gramegna M, Yuen KY, Mueller R, Koch D, Sethi S, Rawlinson WD, Clementi M, Erasmus R, Leportier M, Kwon GC, Menezes ME, Patru MM, Singh K, Ferrari M, Najjar O, Horvath A, Adeli K, Lippi G and the IFCC Taskforce on COVID-19
Clin Chem Lab Med, October 2020

Editorial and executive summary: IFCC Interim Guidelines on clinical laboratory testing during the COVID-19 pandemic
Lippi G, Horvath A, Adeli K and the IFCC Taskforce on COVID-19
Clin Chem Lab Med, October 2020
Pathophysiology of COVID-19: Mechanisms Underlying Disease Severity Progression
Bohn MK, Hall A, Sepiashvili L, Jung B, Steele S, Adeli K
Physiology (Bethesda), September 2020
CALIPER Hematology Reference Standards (II)
Higgins V, Tahmasebi H, Bohn MK, Hall A, Adeli K
Am J Clin Pathol, August 2020

CALIPER Hematology Reference Standards (I)
Higgins V, Tahmasebi H, Bohn MK, Hall A, Adeli K
Am J Clin Pathol, August 2020

The association between body mass index trajectories and cardiometabolic risk in young children
Li X, Keown-Stoneman CDG, Lebovic G, Omand JA, Adeli K, Hamilton JK, Hanley AJ, Mamdani M, McCrindle BW, Sievenpiper JL, Tremblay MS, Maguire JL, Parkin PC, Birken CS; TARGet Kids! Collaboration
Pediatr Obes, August 2020

Laboratory practices to mitigate biohazard risks during the COVID-19 outbreak: an IFCC global survey
Loh TP, Horvath AR, Wang CB, Koch D, Lippi G, Mancini N, Ferrari M, Hawkins R, Sethi S, Adeli K, IFCC Taskforce on COVID-19
Clin Chem Lab Med, June 2020

Operational considerations and challenges of biochemistry laboratories during the COVID-19 outbreak: an IFCC global survey
Loh TP, Horvath AR, Wang CB, Koch D, Adeli K, Mancini N, Ferrari M, Hawkins R, Sethi S, Lippi G, IFCC Taskforce on COVID-19
Clin Chem Lab Med, June 2020

Molecular, serological, and biochemical diagnosis and monitoring of COVID-19: IFCC taskforce evaluation of the latest evidence
Bohn MK, Lippi G, Horvath A, Sethi S, Koch D, Ferrari M, Wang CB, Mancini N, Steele S, Adeli K
Clin Chem Lab Med, June 2020

Biosafety measures for preventing infection from COVID-19 in clinical laboratories: IFCC Taskforce Recommendations
Lippi G, Adeli K, Ferrari M, Horvath AR, Koch D, Sethi S, Wang CB
Clin Chem Lab Med, June 2020

Comprehensive hematological reference intervals in a healthy adult male population
Ghazizadeh H, Kathryn Bohn M, Kardagh Polus R, Abdulkarimi R, Mahdavizadeh V, Ghaffarian Zirak R, Kamel Khodabandeh A, Zare-Feyzabadi R, Timar A, Mohammadi-Bajgiran M, Oladi MR, Esmaily H, Sharifan P, Sahranavard T, Kazemi E, Ekhteraee Toosi MS, Taghizadeh N, Najar Sedgh Doust F, Ferns GA, Adeli K, Ghayour-Mobarhan M
Cell Mol Biol (Noisy-le-grand), May 2020

Bile acid treatment and FXR agonism lower postprandial lipemia in mice
Farr S, Stankovic B, Hoffman S, Masoudpoor H, Baker C, Taher J, Dean A, Anakk S, Adeli K
Am J Physiol Gastrointest Liver Physiol, April 2020

Marked Influence of Adiposity on Laboratory Biomarkers in a Healthy Cohort of Children and Adolescents
Higgins V, Omidi A, Tahmasebi H, Asgari S, Gordanifar K, Nieuwesteeg M, Adeli K
J Clin Endocrinol Metab, April 2020

Postprandial Dyslipidemia, Hyperinsulinemia, and Impaired Gut Peptides/Bile Acids in Adolescents With Obesity
Higgins V, Asgari S, Hamilton JK, Wolska A, Remaley AT, Hartmann B, Holst JJ, Adeli K
J Clin Endocrinol Metab, April 2020

Influence of ethnicity on biochemical markers of health and disease in the CALIPER cohort of healthy children and adolescents
Tahmasebi H, Asgari S, Hall A, Higgins V, Chowdhury A, Thompson R, Bohn MK, Macri J, Adeli K
Clin Chem Lab Med, March 2020

miR-130b is a potent stimulator of hepatic VLDL assembly and secretion via marked induction of microsomal triglyceride transfer protein (MTP)
Zhang J, Jazii FR, Haghighi MM, Alvares D, Liu L, Khosraviani N, Adeli K
Am J Physiol Endocrinol Metab, February 2020

Screening for Nonclassic Congenital Adrenal Hyperplasia in the Era of Liquid Chromatography-Tandem Mass Spectrometry
Chesover AD, Millar H, Sepiashvili L, Adeli K, Palmert MR, Hamilton J
J Endocr Soc, December 2019

The Role of the Gut Microbiota in Lipid and Lipoprotein Metabolism
Yu Y, Raka F, Adeli K
J Clin Med, December 2019
Paediatric reference intervals for 17 Roche cobas 8000 e602 immunoassays in the CALIPER cohort of healthy children and adolescents
Bohn MK, Higgins V, Asgari S, Leung F, Hoffman B, Macri J, Adeli K
Clin Chem Lab Med, November 2019
Metabolic control via nutrient-sensing mechanisms: role of taste receptors and the gut-brain neuroendocrine axis
Raka F, Farr S, Kelly J, Stoianov A, Adeli K
Am J Physiol Endocrinol Metab, October 2019

Choosing the best statistical method for reference interval estimation
Higgins V, Asgari S, Adeli K
Clin Biochem, September 2019

Characterisation of serum total tau following paediatric traumatic brain injury: a case-control study
Stukas S, Higgins V, Frndova H, Gill J, Hubara E, Guerguerian AM, Boutis K, Beauchamp M, Farrell C, Babl FE, Delzoppo C, Greenham M, Wilkinson AA, Crichton A, Anderson V, Adeli K, Hutchison J, Wellington C; Serum Biomarkers and Quality of Life in Children with Traumatic Brain Injury investigators; National Biobank and Database for Patients with Traumatic Brain Injury investigators; Canadian Critical Care Translation Biology Group, and the Canadian Traumatic Brain Injury Research Consortium
Lancet Child Adolesc Health, August 2019

Intestinal lipogenesis: how carbs turn on triglyceride production in the gut
Hoffman S, Alvares D, Adeli K
Curr Opin Clin Nutr Metab Care, July 2019

Association of accelerated body mass index gain with repeated measures of blood pressure in early childhood
Eny KM, Maguire JL, Dai DWH, Lebovic G, Adeli K, Hamilton JK, Hanley AJ, Mamdani M, McCrindle BW, Tremblay MS, Parkin PC, Birken CS; TARGet Kids! Collaboration
Int J Obes (Lond), July 2019

Morphoquantitative effects of oral β-carotene supplementation on liver of C57BL/6 mice exposed to ethanol consumption
Sandoval C, Vásquez B, Souza-Mello V, Adeli K, Mandarim-de-Lacerda C, Del Sol M
Int J Clin Exp Pathol, May 2019

Gut peptide and neuroendocrine regulation of hepatic lipid and lipoprotein metabolism in health and disease
Alvares D, Hoffman S, Stankovic B, Adeli K
Biochim Biophys Acta Mol Cell Biol Lipids, March 2019