Joel P. Ross, Research Associate, 2010-2016

Originally from New Brunswick, Joel obtained his B.Sc. from the University of New Brunswick and his PhD from the University of Ottawa. His doctoral research with Dr. Robin Parks explored the role of chromatin in the regulation of adenovirus vector-encoded transgenes. His research in the Ellis lab employed induced pluripotent stem cell technology to generate novel cell-based models of autism spectrum disorders. Ross’ long-term goal was to examine the relative contribution of genetic and epigenetic factors in the development of neuropsychiatric diseases. His research was funded by the Ontario Stem Cell Initiative Fellowship Program.

 

Next Position: Assistant Professor in the Department of Biology at the University of Prince Edward Island.

 

Selected Publications:

Ross, P.J.+, W. Zhang+, R.S.F. Mok, K. Zaslavsky, E. Deneault, L. D’Abate, D.C. Rodrigues, R.K.C. Yuen, M. Faheem, M. Mufteev, A. Piekna, W. Wei, P. Pasceri, R.J. Landa, A. Nagy, B. Varga, M.W. Salter, S.W. Scherer and J. Ellis. 2020. Synaptic Dysfunction in Human Neurons with Autism-Associated Deletions in PTCHD1-AS. +Co-first authors. Biological Psychiatry 87:139-149.
 
Ross P.J.*, R.S.F. Mok, B.S. Smith, D.C. Rodrigues, M. Mufteev, S.W. Scherer and J. Ellis. 2020. Modeling neuronal consequences of autism-associated gene regulatory variants with human induced pluripotent stem cells. *Corresponding author. Molecular Autism 11:33.

Zhang WB, Ross PJ, Tu Y, Wang Y, Beggs S, Sengar AS, Ellis J, Salter MW. (2016) Fyn Kinase regulates GluN2B subunit-dominant NMDA receptors in human induced pluripotent stem cell-derived neurons. Science Reports. Apr 4;6:23837.

Khattak S, Brimble E, Zhang W, Zaslavsky K, Strong E, Ross PJ, Hendry J, Mital S, Salter MW, Osborne LR, Ellis J. (2015) Human induced pluripotent stem cell derived neurons as a model for Williams-Beuren syndrome. Molecular Brain. Nov 24;8(1):77.

Djuric U, Cheung AY, Zhang W, Mok RS, Lai W, Piekna A, Hendry JA, Ross PJ, Pasceri P, Kim DS, Salter MW, Ellis J. (2015) MECP2e1 isoform mutation affects the form and function of neurons derived from Rett syndrome patient iPS cells. Neurobiology of Disease. Jan 30;76C:37-45.

Ross PJ. and Ellis J. (2010) Modeling complex neuropsychiatric disease with induced pluripotent stem cells. F1000 Biology Reports. 2:84.