JOURNAL ARTICLES (Published or In Press)
Currie G, Marshall D, Dal Ben R, Yeung RSM, Vastert S, Wulffraat N, Swart JF, Benseler S: Work productivity loss and activity impairment in parents of children with juvenile idiopathic arthritis. The Journal of Pediatrics. In press. C
Kip MMA, Avantil JA, Marinescu R, Oudshoorn CGM, Currie G, Benseler SM, Swart JF, Vastert B, Wulfraat N, Yeung RSM, Marshall D, Ijzerman MJ: Development and qualitative evaluation of a decision support tool for withdrawal of biologic therapy in non-systemic juvenile idiopathic arthritis. MDM Policy & Practice. In press. C
Shapiro JR, Choi F, Xu A, Duong TT, Gingras AC, Colwill K, Bernatsky S, Benseler SM, Yeung RSM and on behalf of the SUCCEED Kids Team: Immunogenicity of COVID-19 booster vaccines in children receiving immunosuppressive medications. Nature. In press. C
Wong S, Guzman J, Chan M, Morishita K, Tucker L, Houghton K, Cabral D, Oen K, Duffy C, Berard R, Chedeville, Loughin T, Yeung RSM: A tale of many Canadas: Associations of ancestry with Juvenile Idiopathic Arthritis categories and disease severity at presentation to care. ACR Open Rheumatology. In press. C
Kirolos N, Mtaweh H, Datta RR, Farrar DS, Seaton C, Bone JN, Muttalib F, Kaziev CL, Fortini J, Manhant , Campigotto A, Freire G, Yeung RSM, Rayment JH, Yang C, Srigley JA, Sadarangani M, Buchanan F, Morris SK, Gill PJ, for the READAPT-Kids Study Group Members: Risk factors for severe disease among children hospitalized with respiratory syncytial virus. JAMA Network Open 2025:8(4):e254666. C
MacMahon JM, Massumi M, Duong TT, Garrett RH, Bell-Peter A, Whitney K, Marcuz JA, Goh I, Yeung RSM, Feldman BM: Correlation between interferon response gene score and disease activity in juvenile dermatomyositis. The Journal of Rheumatology DOI: https://doi.org/10.3899/jrheum.2024-0806. Co-SRI
Shapiro J, Choi F, Xu A, Duong TT, Gingras AC, Colwill K, Bernatsky S, Benseler S, Yeung RSM on behalf of the SUCCEED KIDS Team: Fourth COVID-19 vaccine dose repairs the magnitude and durability of antibody responses in children receiving biologic medications. Pediatric Research (conditionally accepted). SRI
Gill PJ, Kaziev CL, Mtaweh H, Kant T, Seaton C, Farrar DS, Wagman H, Han M, Dhatta RR, Mahant S, Freire G, Campigotto A, Bone JN, Sadarangani M, Buchanan F, Morris SK, for the READAPT-Kids Study: Performance of the World Health Organization (WHO) severe acute respiratory infection (SARI) case definitions in hospitalized children and youth: cross-sectional study. The Lancet Regiona Health – Americas 2025:44: 10134. C
Truong DT, Trachtenberg FL, Hu C, Pearson GD, Friedman K, Sabati AA, Dionne A, Oster ME, Anderson BR, Block J, Bradford TT, Campbell J, L’Addese L Dummer KB, Elias MD, Forsha D, Garuba OD, Hasbani K, Hayes K, Hebson C, Jone PN, Krishnan A, Lang S, McCrindle BW, McHugh KE, Mitchell EC, Morrison T, Muniz JC, Payne M, Portman MA, Russell MW, Sanil Y, Shatki D, Sharma K, Shea R, Sykes M, Shekerdemian LS, Szmuskovicz J, Thacker D, Newburger JW, for the MUSIC Study Investigators: Six-month outcomes in the long-term outcomes after the multisystem inflammatory syndrome in children study. JAMA Pediatr. 2025:179(3):293-301. doi:10.1001/jamapediatrics.2024.5466. C
Lee JJ, Widdifield J, Benchimol E, Kwong J, Li Q, Yeung RSM, Bernatsky S: Safety and health care utilization following COVID-19 vaccination (BNT162b2) among children and youth with Juvenile Idiopathic Arthritis (JIA) and Inflammatory Bowel Disease (IBD) – a population-based study. Pediatrics and Child Health pxae 101, https://doi.org/10.1093/pch/pxae101 C
Farrar DS, Bettinger JA, Campigotto AJ, Deeks SL, Drouin O, Embree JE, Haddad E, Halperin SA, Jadavji T, Kazmi K, King M, Moore Hepburn C, Papenburg J, Purewal R, Sadarangani M, Sauve L, Yeung RSM, Top KA, Kakkar F, Morris SK and on behalf of the Canadian Immunization Monitoring Program, Active (IMPACT) Investigators: Pediatric COVID-19 severity by SARS-CoV-2 lineage and vaccine status in Canada: an IMPACT study. Pediatric Research 2025: https://doi.org/10.1038/s41390-025-03853-0. C
Barbaric A, Christofferson K, Benseler SM, Lalloo C, Mariakakis A, Pham Q, Swart JF, Yeung RSM, Cafazzo JA: Health recommender systems to facilitate collaborative decision-making in chronic disease management: a scoping review. Digital Health 2025:11:1-16. https://doi.org/10.1177/20552076241309386. C
Gagne S, Sivaraman V, Bosman E, Klamer B, Morishita K, Huber A, Orjuela, Berhard BE, Myrup C, Gerst, Foell D, Al-Abadi E, McErlane F, Phillippi-Cook K, Wagner L, Elderme, Moorth LN, Dancey P, Yeung RSM, Chandani R, Deepak S, Tarvin SE, Shenoi S, Tanner T, Sirirat, Brown K, Cabral D: Comparing rituximab and Cyclophosphamide in Induction Therapy for Childhood-Onset ANCA-Associated Vasculitis: An ARChiVe registry-cohort study. Arthritis Care and Research. 2024:77(4):504-512. C
Marshall DA, Dal Ben R, Currie G, Vastert SJ, Yeung RSM, Kip MMA, Swart JF, Benseler S: PCR 149 burden of childhood arthritis: work productivity loss and activity impairment of parents and caregivers. Value in Health 2024:27:12: S535. C
Marshall DA, Gerber B, Currie GR, Anton J, de Somer L, Dey M, Egert T, Egert Y, Henan L, Klotsche J, Mifsut LM, Minden K, Normand C, Porte D, Saurenmann RK, Swart JF, Uziel Y, Wilson J, Wouters C, Ziv A, Benseler SM, PAVE Consortium: Uncovering the hidden socioeconomic impact of juvenile idiopathic arthritis and paving the way for other rare childhood diseases: an international, cross-disciplinary, patient-centered approach (PAVE Consortium). Pediatric Rheumatology Online Journal 2024:9;22(1):74. C
Soulsby WD, Olveda R, He J, Berbert L, Weller E, Barbour KE, Greenlund KJ, Schanberg LE, von Scheven E, Hersh A, Son MB, Chang J, Knight A, on behalf of the CARRA Registry Investigators: Racial disparities and achievement of the low lupus disease activity state: a CARRA registry study. Arthritis Care and Research 2024: 77: 1: 38-49. C
Roumeliotis N, Carwana M, Trudeau O, Charland K, Zinszer K, Benigeri M, Diop M, Papenburg J, Ali S, Yaskina M, Wahi G, d’Arc BF, Cote S, Sadarangani M, Basta NE, Fontela PS, Gantt S, Klassen TP, Quach C, Doan Q, POPCORN Investigators: Mental health hospitalizations in Canadian children, adolescents, and young adults over the COVID-19 pandemic. JAMA Network Open 2024: 1;(7):e2422833. C
Mann SK, Bone JF, Bosman ES, Cabral DA, Morishita KA, Brown KL, PedVas Investigator Network: Predictive utility of ANCA positivity and antigen specificity in the assessment of kidney disease in paediatric-onset small vessel vasculitis. RMD Open 2024:17;10(2):e004315. C
Berard RA, Tam H, Succimarri R, Haddad E, Morin MP, Chan KJ, Dahdah NS, McCrindle BW, Price VE, Yeung RSM, Laxer RM, Acute Care Committee: Paediatric inflammatory multisystem syndrome temporally associated with COVID-19 (spring 2021 update): Canadian Pediatric Society. 2024. C
Dissanayake D, Firouzabady A, Massumi M, de Paz Linares G, Marshall C, Freeman SA, Laxer RM, Yeung RSM: Interleukin-1 mediated hyperinflammation in XIAP-deficiency is associated with defective autophagy. Blood 2024:144(11):1183-1192. SRI
Correia Marques M, Rubin D, Shuldiner EG, Datta M, Schmitz E, Cruz GG, Patt A, Bennett E, Grom A, Foell D, Gattorno M, Bohnsack J, Yeung RSM, Prahalad S, Mellins E, Anton J, Len CA, Oliveira S, Woo P, Ozen S, INCHARGE consortium, Deng Z, Ombrello MJ. Enrichment of rare variants of hemophagocytic lymphohistiocytosis genes in systemic juvenile idiopathic arthritis. Arthritis and Rheumatology 2024:76:10:1566-1572. C
Ohinmaa A, Wen J, Currie GR, Benseler SM, Swart JF, Vastert SJ, Yeung RSM, Marshall DA: Validation of the EQ-5D-Y-5L parent-proxy version among children with juvenile idiopathic arthritis. Qality of Life Research. 2024:33:2677-2691. C
Tsoukas P, Yeung RSM: Kawasaki Disease-Associated Cytokine Storm Syndrome. Adv Exp Med Biology 2024:1448:365-383. SRI
Toor KK, Chen A, Cabral DA, Mammen C, Bosman ES, Shen Y, Bone JN, No-one D, Al-Abadi E, Benseler S, Berard R, Bohm M, Charuvanij S, Cook K, Dancey P, Deepak S, Duffy C, Eberhard B, Elder M, Foell D, Gerstbacher D, Heshin-Bekenstein M, Huber A, James KE, Kim S, Klein-Gitelman M, Martin N, McErlane F, Moorthy LN, Myrup C, Riley P, Shenoi S, Sivaraman V, Tanner T, Tarvin S, Wagner-Weiner L, Yeung RSM, Brown KL, Morishita KA on behalf of the PedVas Investigators Network: Evaluating Renal Disease in Pediatric-Onset Antineutrophil Cytoplasmic Antibody–Associated Vasculitis: Disease Course, Outcomes, and Predictors of Outcome. Arthritis and Rheumatology. 2024. C
Saper VE, Tian L, Verstegen R, Conrad CK, Cidon M, Hopper RK, Kuo CS, Osoegawa K, Baszis K, Bingham CA, Ferguson I, Hahn T, Horne A, Isupova EA, Jones JT, Kasapcopur O, Klein-Gitelman MS, Kostik MM, Ozen S, Phadke O, Prahalad S, Randell R, Sener S, Stingl C, Abdul-Aziz R, Akoghlanian S, Al Julandani D, Alvares MB, Bader-Meunier B, Balay-Dustrude EE, Balboni I, Baxter SK, Berard RA, Bhattad S, Bolaria R, Boneparth A, Cassidy EA, Co DO, Collins KP, Dancey P, Dickinson AM, Edelheit BS, Espada G, Flanagan ER, Imundo LF, Jindal AK, Kim H-A, Klaus G, Lake C, Lapin WB, Lawson EF, Marmor I, Mombourquette J, Ogunjimi B, Olveda R, Ombrello MJ, Onel K, Poholek C, Ramanan AV, Ravelli A, Reinhardt A, Robinson AD, Rouster-Stevens K, Saad N, Schneider R, Selmanovic V, Pasic IS, Shenoi S, Shilo NR, Soep JB, Sura A, Taber SF, Tesher M, Tibaldi J, Torok KS, Tsin CM, Vasquez-Canizares N, Nunes DSV, Way EE, Whitehead B, Zemel LS, Sharma S, Fernandez-Vina MA, Mellins ED and the CARRA Registry Investigators: Interleukin (IL)1/IL-6-inhibitor associated drug reaction with eosinophilia and systemic symptoms (DReSS) in systemic inflammatory illnesses. The Journal of Allergy and Clinical Immunology 2024: 12: 11: 2996-3013. C
Florax AA, Doeleman MJH, de Roock S, van der Linden N, Schatorje E, Currie G, Marshall DA, IJzerman MJ, Yeung RSM, Benseler SM, Vastert SJ, Wulfraat NM, Swart JF, Kip MMA, UCAN-CAN DU and UCAN Consortia: Quantifying hospital-associated costs, and accompanying travel costs and productivity losses, before and after withdrawing TNF-a inhibitors in juvenile idiopathic arthritis. Rheumatology 2024: 00, 1-9. C
Van Til JA, Kip MMA, Marinescu-Muster R, Groothuis-Oudshoorn CGM, Currie G, Benseler SM, Swart JF, Vastert SJ, Wulffraat N, Yeung RSM, Marshall DA, Ijzerman MJ: Development of a decision support tool for biologic therapy withdrawal decisions in non-systemic juvenile idiopathic arthritis. Medical Decision Making. 2023: 44:2NP53-NP55. C
Jones JT, Smith C, Becker ML, Lovell D, for the CARRA Registry Investigators. Down syndrome -associated arthritis cohort in the new Childhood Arthritis and Rheumatology Research Alliance Registry: clinical characteristics, treatment and outcomes. Arthritis Care and Research. 2023: 73(12): 1739-1745. C
Rumsey DG, Lougee A, Matsouka R, Coliier DH, Schanberg LE, Schenfeld J, Shiff NJ, Stoll ML, Stryker S, Weiss PF, Beukelman T, for the Childhood Arthritis and Rheumatology Research Alliance Registry Investigators. Juvenile spondyloarthritis in the Childhood Arthritis and Rheumatology Research Alliance Registry: high biologic use, low prevalence of HLA-B27, and equal sex representation in sacroiliitis. Arthritis Care and Research. 73(7): 940-946. C
Yeung RSM: What’s in a name? That which we call JIA, by any other name, would still be the same childhood arthritis? The Journal of Rheumatology 2023:50:7: 2-6. SRI
Farrar D, Hepburn CM, Drouin O, El Tal T, Morin MP, Berard RA, King M, Thibodeau ML, Baerg K, Beaudoin-Bussieres G, Beaufils C, Bennett TL, Benseler S, Chan K, Cyr C, Dahdah N, Donner E, Embree J, Farrell C, Finzi A, Forgie S, Giroux R, Kang K, Lang B, Laxer R, McCrindle B, Orkin J, Papenburg J, Pound C, Price V, Proulx-Gauthier JP, Purewal R, Sadarangani M, Salvadori M, Thibeault R, Top K, Viel-Theriault I, Haddad E, Scuccimarri R, Yeung RSM, Kakkar F, Morris S, the Canadian Pediatric Surveillance Program COVID-19 Study Team: Resource use and disease severity of children hospitalized for COVID-19 versus multisystem inflammatory syndrome in children (MIS-C) in Canada. Canada Communicable Disease Report 2023:49(4):103-112. C
Wilhelmsson M, Chun FJ, Yeung RSM, Krtizinger F, McKeown T, Coblentz A, Ertl-Wagner B, Tabori U, Bartels U: Sarcoid-like reaction in a child following prolonged therapeutic exposure to dabrafenib and trametinib for BRAF V600E mutated hypothalamic/chiasmatic glioma. Authorea. July 12, 2023. C
Currie GR, Groothuis-Oudshoorn K, Twilt M, Kip MM, IJzerman MJ, Benseler SM, Swart JF, Vastert SJ, Wulffraat NM, Yeung RSM, Marshall DA: What matters most to pediatric rheumatologists in deciding whether to withdraw biologics in a child with juvenile idiopathic arthritis: a best-worst scaling study. Clinical Rheumatology 2023: 42(8): 2173-2180. C
El Tal T, Morin MP, Morris SK, Farrar DS, Berard RA, Kakkar F, Hepburn CM, Baerg K, Beaufils C, Bennett TL, Benseler SM, Beaudoin-Bussieres G, Chan K, Cyr C, Dahdah N, Donner EJ, Drouin O, Edjoc R, Eljaouhari M, Embree JE, Farrell C, Finzi A, Forgie S, Giroux R, Tang KT, King M, Thibodeau ML, Lang B, Laxer RM, Luu TM, McCrindle BW, Orkin J, Papenburg J, Pound CM, Price VE, Proulx-Gauthier JP, Purewal R, Sadarangani M, Salvadori MI, Thibeault R, Top KA, Viel-Theriault I, Haddad E, Scuccimarri R and Yeung RSM: Pediatric inflammatory multisystem syndrome in Canada: population-based surveillance and role of SARS-CoV2 linkage. Pediatric Research 2023: 94:1744-1753. SRI
Branch DR, Leger RM, Sakac D, Yi Q, Duong TT, Yeung RSM, Binnington B, Block EM. The chemokines IP-10/CXLC10 and IL-8/CXCL8 are potential novel biomarkers of warm autoimmune hemolytic anemia. Blood Advances. 2023:7(10): 2166-2170. C
Currie GR, Kennedy BL, Benseler SM, Yeung RSM, Swart JF, Vastert SJ, Wulffraat NM, Kip MMA, MacKean G, Marshall DA: managing juvenile idiopathic arthritis within the context of their life: what we learnt from children and youth living with juvenile idiopathic arthritis and their parents. Musculoskeletal Care 2023:21:1248-1260. C
Gibson KM, Drogemoller BI, Foell D, Benseler SM, Graham J, Hancock REW, Luqmani RA, Cabral DA, Brown KL, Ross CJ on behalf of the PedVas Investigators Network: Association between HLA-DPB1 and antineutrophil cytoplasmic antibody-associated vasculitis in children. Arthritis and Rheumatology 2023: 75(6):1048-1057. C
Shiff NJ, Shrader P, Correll CK, Dennos A, Phillips T, Beukelman T, the CARRA Registry Investigators. Trajectories of disease activity in patients with JIA in the Childhood Arthritis and Rheumatology Research Alliance Registry. Rheumatology. 2023:62(2): 804-814. C
Yeung RSM: The evolution of JIA. Canadian Rheumatology Association Journal 2023. SRI.
Currie GR, Gerber B, Lorenzetti D, MacDonald K, Benseler SM, Bernier FP, Boycott KM, Carias KV, Hamelin B, Hayeems RZ, LeBlanc C, Twilt M, van Rooijen G, Wong-Rieger D, Yeung RSM, Marshall DA: Developing a framework of cost elements of socioeconomic burden of rare disease: a scoping review. Pharmacoeconomics 2023: 41:803-818. C
Smitherman EA, Chahine RA, Beukelman T, Lewandowski LB, Rahman AKMF, Wenderfer SE, Curtis JR, Hersh AO for the CARRA Registry Investigators. Childhood-onset lupus nephritis in the childhood arthritis and rheumatology research alliance registry: short-term kidney status and variation in care. Arthritis Care and Research. 2023:75(7): 1553-1562. C
Woo JMP, Simmonds F, Dennos A, Son MBF, Lewandowski LB, Rubinstein TB, for the CARRA Registry investigators. Health equity implications of missing data among youths with childhood-onset systemic lupus erythematosus: a proof-of-concept study in the childhood arthritis and rheumatology research alliance registry. Arthritis Care and Research. 2023:75(11): 2285-2294. C
Yoo S, Garg E, Elliott LT, Hung RJ, Halevy AR, Brooks JD, Bull SB, Gagnon F, Greenwood CMT, Lawless JF, Paterson AD, Sun L, Zawati MH, Lerner-Ellis J, Abraham RJS, Birol I, Bourque G, Garant JM, Gosselin C, Li J, Whitney J, Thiruvahindrapuram B, Herbrick JA, Lorenti M, Reuter MS, Adele OO, Liu S, Allen U, Bernier FP, Biggs CM, Cheung AM, Cowan J, Herridge M, Maslove DM, Modi BP, Mooser V, Morris SK, Ostrowski M, Parekh RS, Pfeffer G, Suchowersky O, Taher J, Upton J, Warren RL, Yeung RSM, Aziz N, Turvey SE, Knoppers BM, Lathrop M, Jones SJM, Scherer SW, Strug LJ. HostSeq: a Canadian whole genome sequencing and clinical data resource. BMC Genomic Data. 2023:24:26. C
Go E, Aeschlimann FA, Lu H, Larry JR, Hebert D, Yeung RSM, Noone D. (2023). Von Willebrand factor antigen as a marker of disease activity in childhood-onset antineutrophil cytoplasmic antibody-associated vasculitis. Rheumatology. DOI: 10.1093/rheumatology/kead600. Co-SRI
Alphonse MP, Duong TT, Tam S, Yeung RSM. Mercury increases IL-1B and IL-18 secretion and intensifies coronary arteritis in an animal model of Kawasaki disease. Frontiers in Immunology. 2023:14:1126154. SRI
Elias MD, Truong DT, OSter ME, Trachtenberg FL, Mu X, Jone PN, Mitchell EC, Dummer KB, Tejtel SKS, Osakwe O, Thacker D, Su JA, Bradford TT, Burns KM, Campbell MJ, Connors TJ, D’Addese L, Forsha D, Frosch OH, Giglia TM, Goodell LR, Handler SS, Hasbani K, Hebson C, Krishnan A, Lang SM, McCrindle BW, McHugh KE, Morgan LM, Payne RM, Sabati A, Sagiv E, Sanil Y, Serrano F, Newburger JW, Dionne A, for the Pediatric Heart Network MUSIC Study Investigators. Examination of adverse reactions after COVID-19 vaccination among patients with a history of multisystem inflammatory syndrome in children. JAMA Network. 2023: 6(1): e2248987. C
Fridman MD, Tsoukas P, Jeewa A, Yeung RSM, Gamulka BD, McCrindle BW: Differentiation of COVID-19-associated multisystem inflammatory syndrome from Kawasaki Disease with the use of cardiac biomarkers. Canadian Journal of Cardiology 2023:815-823. C
The COVID-19 Host Genetics Initiative: A second update on mapping the human genetic architecture of COVID-19. Nature 2023: 621(7977):E7-E26. C
Ringold S, Dennos AC, Kimura Y, Beukelman T, Shrader P, Phillips TA, Kohlheim M, Schanberg LE, Yeung RSM, Horton DB on behalf of the CARRA Registry Investigators: Disease recapture rates after medication discontinuation and flare in JIA: an observational study within the childhood arthritis and rheumatology research alliance registry. Arthritis Care and Research 2023:75:4:715-723.. C
Nguyen K, Barsalou J, Basodan D, Batthish M, Benseler SM, Berard RA, Blanchette N, Boire G, Bolaria R, Bruns A, Cabral DA, Cameron B, Campillo S, Cellucci T, Chan M, Chedeville G, Chetaille AL, Chhabra A, Couture J, Dancey P, De Bruycker JJ, Demirkaya E, Dhalla M, Duffy CM, Feldman BM, Feldman DE, Gerschman T, Haddad E, Heale L, Herrington J, Houghton K, Huber AM, Human A, Johnson N, Jurencak R, Lang B, Larche M, Laxer RM, Leblanc CM, Lee JJY, Levy DM, Lim L, Lim LSH, Luca N, McGrath T, McMillan T, Miettunen PM, Morisihita KA, Ng HY, Oen K, Park J, Petty RE, Proulx-Gauthier JP, Ramsey S, Roth J, Rosenberg AM, Rozenblyum E, Rumsey DG, Schmeling H, Schneider R, Scuccimarri R, Shiff NJ, Silverman E, Soon G, Spiegel L, Stringer E, Tam H, Tse SM, Tucker LB, Turvey S, Twilt M, Duffy KW, Yeung RSM, Guzman J for the ReACCh-Out and CAPRI Registry Investigators. (2023). A decade of progress in juvenile idiopathic arthritis treatments and outcomes in Canada: results from ReACCh-Out and the CAPRI registry. Rheumatology. 2024: 63: SI1173-1179. C
Van Til JA, Kip MMA, Schatorje EJH, Currie G, Twilt M, Benseler SM, Swart JF, Vastert SJ, Wulfraat N, Yeung RSM, Groothuis-Oudshoorn CGM, Warta S, Marshall DA, IJzerman MJ and on behalf of the UCAN CAN-DU, UCAN CURE consortia. Withdrawing biologics in non-systemic JIA: what matters to pediatric rheumatologists? Pediatric Rheumatology 2023: 21:69. C.
Oen K, Toupin-April K, Feldman BM, Berard RA, Duffy CRM, Tucker LB, Tian J, Rumsey DG, Guzman J, ReACCh-Out investigators: Validation of the parent global assessment as a health-related quality of life measure in juvenile idiopathic arthritis: results from ReACCh-Out. Rheumatology 2023: 62(S12):SI 152-SI162. C
Currie GR, Pham T, Twilt M, IJzerman MJ, Hull PM, Kip MMA, Benseler SM, Hazlewood GS, Yeung RSM, Wulffraat NM, Swart JF, Vastert SB, Marshall DA: Perspectives of pediatric rheumatologists on initiating and tapering biologics in patients with juvenile idiopathic arthritis: a formative qualitative study. Springer Nature 2022: 15(5):599-609. C
Grazziotin LR, Currie G, Twilt M, IJzerman MJ, Kip MMA, Koffijberg H, Bonsel G, Benseler SM, Swart JF, Vastert SJ, Wulffraat NM, Yeung RSM, Armbrust W, van den Berg JM, Marshall DA: Factors associated with care- and health- related quality of life of caregivers of children with juvenile idiopathic arthritis. Pediatric Rheumatology 2022: 20(1):51. C
Aeschlimann FA, Yeung RSM, Laxer RM: An update on childhood-onset Takayasu Arteritis. Frontiers in Pediatrics 2022: https://doi.org/10.3389/fped.2022.872313. Co-SRI
Lee JJY, Lin E, Widdifield J, Mahmood Q, McCrindle BW, Yeung RSM, Feldman BM: The long-term cardiac and noncardiac prognosis of Kawasaki disease: a systematic review. Pediatrics 2022: 149(3):e2021052567. co-SRI
Mulla I, Yeung RSM, Noon DG, Bell-Peter A, Pagnoux C: Pediatric-to-adult transition experience in vasculitis: report of a model of care and outcomes. Clinical and Experimental Rheumatology 2022: 40(4):772-778. C
Grazziotin LR, Currie G, Twilt M, IJzerman MJ, Kip MMA, Koffijberg H, Benseler SM, Swart JF, Vastert SJ, Wulffraat, Yeung RSM, Marshall D: Real-world data reveals the complexity of disease modifying anti-rheumatic drug treatment patterns in juvenile idiopathic arthritis: an observational study. Pediatric Rheumatology 2022:20(1):25. C
Lee JJY, Feldman BM, McCrindle BW, Li P, Yeung RSM, Widdifield J: Evaluating the time-varying risk of hypertension, cardiac events, and mortality following Kawasaki disease diagnosis. Pediatric Research 2023:93:5:1439-1446. C
Kip MMA, de Roock S, Currie G, Marshall DA, Grazziotin LR, Twilt M, Yeung RSM, Benseler SM, Vastert SJ, Wulffraat N, Swart JF, IJzerman MJ: Pharmacological treatment patterns in patients with juvenile idiopathic arthritis in the Netherlands: a real-world data analysis. Rheumatology 2023:62:SI12:SI170-SI180. C
Verstegen RHJ, Shrader P, Balevic SJ, Beukelman T, Correll C, Dennos A, Phillips T, Feldman BM for the CARRA Registry Investigators: Dosing variation at initiation of adalimumab and etanercept and clinical outcomes in juvenile idiopathic arthritis: a childhood arthritis and Rheumatology Research Alliance Registry Study. Arthritis Care and Research 2022:75:2:410-422. C
Kip MMA, de Roock S, van den Berg I, Currie G, Marshall DA, Grazziotin LR, Twilt M, Yeung RSM, Benseler SM, Vastert SJ, Wulffraat N, Swart JF, IJzerman MJ: Costs of hospital-associated care for patients with juvenile idiopathic arthritis in the Dutch healthcare system. Arthritis Care and Research 2022: 74:10:1585-1592. C
Brogan P, Yeung RSM, Cleary G, Rangaraj S, Kasapcopur O, Hersh AO, Li S, Paripovic D, Schikler K, Zeft A, Bracaglia C, Eleftheriou D, Pordeli P, Melega S, Jamois C, Gaudreault J, Michalska M, Brunetta P, Cooper JC, Lehane PB and the PePRS Study Group: Phase IIa global study evaluating rituximab for the treatment of pediatric patients with granulomatosis with polyangiitis or microscopic polyangiitis. Arthritis and Rheumatology 2022: 74(1):124-133. C (article featured as “Editor’s Pick” for January 2022). co-PA
Stingl C, Eng SWM, Feldman BF, Pachman LM, Dvergsten J, Fritzler, Yeung RSM, Reed A: Gene expression profiles of treatment response and non-response in children with juvenile dermatomyositis. ACR Open Rheumatology 2022: 4(8):671-681. co-SRI
Chen A, Mammen C, Guzman J, Al-Abadi E, Benseler SM, Berard RA, Gertsbacher D, Heshin-Bekenstein M, Kim S, Klein-Gitelman M, Chavan PP, James KE, Martin N, McErlane F, Myrup C, Noone DG, Raghuram J, Shenoi S, Sivaraman V, Tanner T, Yeung RSM, Cabral DA, Morishita KA, ARChiVe Investigators within the PedVas Initiative: Wide variation in glucocorticoid dosing in pediatric ANCA-associated vasculitis with renal disease: a pediatric vasculitis initiative study. Clinical and Experimental Rheumatology 2022: 40(4): 841-848. C
Tsoukas P, Yeung RSM: Kawasaki disease and MIS-C share a host immune response. Nature Reviews Rheumatology 2022: 18(10):555-556. SRI
Saper VE, Ombrello MJ, Tremoulet AH, Montero-Martin G, Prahalad S, Canna S, Shimizu C, Deutsch G, Tan SY, Remmers EF, Monos D, Hahn T, Phadke OK, Cassidy E, Ferguson I, Mallajosyula V, Xu J, Rosa Duque JS, Chua GT, Ghosh D, Szymanski AM, Rubin D, Burns JC, Tian L, Fernandez-Vina MA, Mellins ED, Hollenbach JA; Drug Hypersensitivity Consortium; INCHARGE consortium: Severe delayed hypersensitivity reactions to IL-1 and IL-6 inhibitors link to common HLA-DRB1*15 alleles. Annals of Rheumatic Diseases 2022: 81(3):406-415. C
Melega S, Brogan P, Cleary G, Hersh AO, Kasapcopur O, Rangaraj S, Yeung RSM, Zeft A, Cooper J, Pordeli P, Kirchner P, Lehane PB: Evaluation of serious infection in pediatric patients with low immunoglobulin levels receiving Rituximab for granulomatosis with polyangiitis or microscopic polyangiitis. Rheumatology Therapies 2022: 9(2):721-734. C
Lee JJY, Eng SWM, Guzman J, Duffy CM, Tucker LB, Oen K, Yeung RSM, Feldman BM on behalf of the ReACCh-Out investigators: A comparison of international league of associations for rheumatology and pediatric rheumatology international trials organization classification systems for juvenile idiopathic arthritis among children in a Canadian arthritis cohort. Arthritis and Rheumatology 2022: 74(8):1409-1419. Co-SRI
Yeung RSM, Mosoiu A, Benseler SM: UCAN CURE: transforming care and optimizing outcomes of children living with arthritis. The Journal of the Canadian Rheumatology Association 2022: 32: 3: 14. SRI
Nigrovic PA, Colbert RA, Holers VM, Ozen S, Ruperto N, Thompson SD, Wedderburn LR, Yeung RSM, Martini A: Publisher Correction: biological classification of childhood arthritis: roadmap to a molecular nomenclature. Nature Reviews Rheumatology 2021: 17(5):257-269. C
Henderson LA, Friedman KG, Son MBF, Kernan KF, Canna SW, Gorelik M, Lapidus SK, Ferris A, Schulert GS, Seo P, Tremoulet AH, Yeung RSM, Karp DR, Bassiri H, Behrens EM, Mehta JJ: Reply to prophylactic anticoagulation: comment on the ACR guidance for management of multisystem inflammatory syndrome in children. Arthritis and Rheumatology 2021: 73(7):1342-1343. C
Calatroni M, Consonni F, Allivoni M, Bettiol A, Jawa N, Fiasella S, Curi D, Abu Rumeileh S, Tomei L, Fortunato L, Gelain E, Gianfreda D, Oliva E, Jeannin G, Salviani C, Emmi G, Bodria M, Sinico RA, Moroni G, Ramirez GA, Bozzolo E, Tombetti E, Monti S, Bracaglia C, Marucci G, Pastore S, Esposito P, Catanose MG, Crapella B, Montini G, Roperto R, Materassi M, Rossi GM, Badalamenti S, Yeung RSM, Romagnani P, Ghiggeri GM, Noone D, Vaglio A: Prognostic factors and long-term outcomes with ANCA-associated kidney vasculitis in childhood. Clinical Journal of American Society of Nephrology 2021: 16(7):1043-1051. C
Rezaei E, Newkirk MM, Li Z, Gordon JR, Oen KG, Benseler SM, Boire G, Cabral DA, Campillo S, Chedeville G, Chetaille AL, Dancey P, Duffy C, Duffy KW, Houghton K, Huber AM, Jurencak R, Lang B, Morishita KA, Petty RE, Ramsey SE, Roth J, Schneider R, Succimarri R, Spiegel L, Stringer E, Tse SML, Tucker LB, Turvey SE, Yeung RSM, Rosenberg AM for the BBOP study group. (2021). Soluble low-density lipoprotein receptor-related protein 1 in Juvenile Idiopathic Arthritis. Journal of Rheumatology. 48(5): 760-766. C
Mendel A, Ennis D, Go E, Bakowsky V, Baldwin C, Benseler SM, Cabral DA, Carette S, Clements-Baker M, Clifford AH, Cohen Tervaert JW, Cox G, Dehghan N, Dipchand C, Dhindsa N, Famorca L, Fifi-Mah A, Garner S, Girard LP, Lessard C, Liang P, Noone D, Makhzoum JP, Milman N, Pineau CA, Reich HN, Rheaume M, Robinson DB, Rumsey DG, Towheed TE, Trudeau J, Twilt M, Yacyshyn E, Yeung RSM, Barra L, Khalidi N, Pagnoux C. (2021). CanVasc consensus recommendations for the management of antineutrophil cytoplasm antibody-associated vasculitis: 2020 update. Journal of Rheumatology. 48(4):555-566. C
Go E, El Tal T, Tsoukas P, Kraus R, Gamulka B, Mizzi T, McCrindle B, Johnstone J, Premji L, Friedman J, Laxer R, Schneider R, Levy D, Dissanayake D, Morris SK, Yeung RSM and the Sickkids MIS-C working group. (2021). Comparing apples to apples in post-COVID associated multisystem inflammatory syndrome in children (MIS-C). Lancet Pre-print. 00: 00. SRI
Go E, van Veenendaal M, Manlhiot C, Schneider R, McCrindle BW, Yeung RSM. (2021). Kawasaki Disease and systemic juvenile idiopathic arthritis – two ends of the same spectrum. Frontiers in Paediatrics 9: 665815. SRI
Heale LD, Houghton KM, Rezaei E, Baxter-Jones ADG, Tupper SM, Muhajarine N, Benseler SM, Boire G, Cabral DA, Campillo S, Chedeville G, Chetaille AL, Dancey P, Duffy C, Duffy KW, Ellsworth J, Guzman J, Huber AM, Jurencak R, Lang B, Laxer RM, Morishita K, Oen KG, Petty RE, Ramsey SE, Roth J, Schneider R, Scuccimarri R, Spiegel L, Stringer E, Tse SML, Tucker LB, Turvey SE, Yeung RSM, Rosenberg AM and the BBOP Study Group: Clinical and psychosocial stress factors are associated with decline in physical activity over time in children with juvenile idiopathic arthritis. Pediatric Rheumatology Online 2021: 29: 19(1):97. C
Rezaei E, Newkirk MM, Li Z, Gordon JR, Oen KG, Benseler SM, Boire G, Cabral DA, Campillo S, Chedeville G, Chetaille AL, Dancey P, Duffy C, Duffy KW, Houghton K, Huber AM, Jurencak R, Lang B, Morishita KA, Petty RE, Roth J, Schneider R, Scuccimarri R, Spiegel L, Stringer E, Tse S, Tucker LB, Turvey SE, Yeung RSM, Rosenberg AM for the BBOP Study Group: Soluble low-density lipoprotein receptor-related protein 1 in juvenile idiopathic arthritis. The Journal of Rheumatology 2021:48(5) 760-766. C
Kimura Y, Schanberg LE, Tomlinson GA, Riordan ME, Dennos AC, Del Gaizo V, Murphy KL, Weiss PF, Natter MD, Feldman BM, Ringold S, and the CARRA STOP-JIA investigators: Optimizing the start time of biologics in polyarticular juvenile idiopathic arthritis: a comparative effectiveness study of childhood arthritis and rheumatology research alliance consensus treatment plans. Arthritis and Rheumatology 2021:73:10:1898-1909. C
Henderson LA, Canna SW, Friedman KG, Gorelik M, Lapidus SK, Bassiri H, Behrens EM, Ferris A, Kernan KF, Schulert GS, Seo P, Son MBF, Tremoulet AH, Yeung RSM, Mudano AS, Tuner AS, Karp DR, Mehta JJ: American College of Rheumatology clinical guidance for multisystem inflammatory syndrome in children (MIS-C) associated with SARS-CoV-2 and hyperinflammation in COVID-19. Version 2. Arthritis and Rheumatology 2021:73(4):e13-e29. C
Ong MS, Ringold S, Kimura Y, Schanberg LE, Tomlinson GA, Natter MC, and the CARRA Registry Investigators: Improved disease course associated with early initiation of biologics in polyarticular juvenile idiopathic arthritis: trajectory analysis of a childhood arthritis and rheumatology research alliance consensus treatment plans study. Arthritis and Rheumatology 2021:73:10: 1910-1920. C
Kraus R, Yeung RSM, Persaud N: Biologic medicine inclusion in 138 national essential medicines lists. Pediatric Rheumatology Online 2021: 19(1):140. co-SRI
Eng SWM, Yeung RSM, Morris Q: The promise of machine learning to inform the management of juvenile idiopathic arthritis: Expert Review of Clinical Immunology 2021: 17(1):1-3. Co-SRI
Henderson LA, Yeung RSM: MIS-C: early lessons from immune profiling. Nature Reviews Rheumatology 2021:17(2):75-76. SRI
Finch SL, Rosenberg AM, Kusalik AJ, Maleki F, Rezaei E, Baxter-Jones A, Benseler SM, Boire G, Cabral D, Campillo S, Chedeville G, Chetaille A-L, Dancey P, Duffy C, Duffy KW, Guzman J, Houghton K, Huber A, Jurencak R, Lang B, Laxer RM, Morishita K, Petty RE, Ramsey SE, Roth J, Schneider R, Scuccimarri R, Stringer E, Tse SML, Tucker LB, Turvey SE, Szafron M Whiting S, Yeung RSM, Vatanparast H, for the BBOP Study Group: Higher concentrations of Vitamin D in Canadian children with Juvenile Idiopathic Arthritis compared to healthy controls are associated with more frequent use of vitamin D supplements and season of birth. Nutrition Research 2021: 92:139-149. C
Grazziotin LR, Currie G, Twilt M, Ijzerman MJ, Kip MMA, Koffijberg H, Benseler SM, Swart JF, Vastert SJ, Wulffraat NM, Yeung RSM, Johnson N, Luca NJ, Miettunen PM, Schmeling H, Marshall DA: Evaluation of real-world healthcare resource utilization and associated costs in children with juvenile idiopathic arthritis: a Canadian retrospective cohort study. Rheumatology and Therapy 2021: 8(3):1303-1322. C
Henderson LA, Canna SW, Friedman KG, Gorelik M, Lapidus SK, Bassiri H, Behrens EM, Ferris A, Kernan KF, Schulert GS, Seo P, Son MBF, Tremoulet AH, Vanderpluym C, Yeung RSM, Mudano AS, Turner AS, Karp DR, Mehta JJ: American College of Rheumatology clinical guidance for Multisystem Inflammatory Syndrome in Children (MIS-C) associated with SARS-CoV-2 and hyperinflammation in COVID-19. Version 3. Arthritis and Rheumatology 2022. https://doi.org/10.1002/art.42062. C
Gupta A, Cafazzo JA, IJzerman MJ, Swart JF, Vastert S, Wulffraat NM, Benseler SM, Marshall D, Yeung RSM, Twilt M: Genomic health literacy interventions in pediatrics: scoping review. Journal of Medical Internet Research 2021: 23(12):e26684. co-SRI
Nigrovic PA, Colbert RA, Holers VM, Ozen S, Ruperto N, Thompson SD, Wedderburn LR, Yeung RSM, Martini A: Biological classification of childhood arthritis: roadmap to a molecular nomenclature. Nature Reviews Rheumatology 2021: 17:306. C
Bruggeman CW, Nagelkerke SQ, Lau W, Manlhiot C, de Haas M, van Bruggen R, McCrindle BW, Yeung RSM, Kuijpers TW: Treatment-Associated Hemolysis in Kawasaki Disease: Association with Blood-Group Antibody Titers in IVIG Products. Blood Advances 2020: 4(14):3416-3426. Co-SRI
Aeschlimann FA, Twilt M, Yeung RSM: Childhood-onset Takayasu Arteritis. European Journal of Rheumatology 2020: 7(Suppl1):s58-S66. SRI
Kip MMA, de Roock S, Currie G, Marshall DA, Grazziotin LR, Twilt M, Yeung RSM, Benseler SM, Schreijer MA, Vastert SJ, Wulffraat N, van Royen-Kerkhof A, Swart JF, IJzerman MJ: Costs of medication use among patients with juvenile idiopathic arthritis in the Dutch healthcare system. Expert Reviews in Pharmacoeconomics and Outcomes Research 2021: 21(5):975-984. C
Shivamurthy V, Guzman J, Huber A, Boire G, Oen K, Duffy KW, Yeung RSM et al. (2020). Feasibility of applying the flare definition using the ACR core set variables in juvenile idiopathic arthritis in routine practice: results from the ReACCh-Out Cohort. Journal of Rheumatology. C
Rezaei E, Hogan D, Trost B, Kusalik AJ, Boire G, Cabral DA, Campillo S, Chedeville G, Chetaille AL, Dancey P, Duffy C, Duffy KW, Eng SWM, Gordon J, Guzman J, Houghton K, Huber AM, Jurencak R, Lang B, Laxer RM, Morishita K, Oen KG, Petty RE, Ramsey SE, Scherer SW, Scuccimarri R, Spiegel L, Stringer S, Taylor-Gjevre RM, Tse SML, Tucker LB, Turvey SE, Tupper S, Wintle RF, Yeung RSM, Rosenberg AM for the BBOP Study Group: Associations of clinical and inflammatory biomarker clusters with juvenile idiopathic arthritis categories. Rheumatology 2020:59(5): 1066-1075. co-SRI
Eng SWM, Olazagasti JM, Goldenberg A, Crowson CS, Oddis CV, Niewold TB, Yeung RSM, Reed AM: A clinically and biologically based subclassification of the idiopathic inflammatory myopathies using machine learning. ACR Open Rheumatology 2020:2:3:158-166. co-SRI
Oen K, Yeung RSM, Ellsworth J, Tse S, Scuccimarri R, Chedeville G, Morishita K, Guzman J, Cabral D, Rosenberg A, Feldman B, Silverman E, Chetaille Anne-L, Dancey P, Benseler SM, Huber A, Miettunen P, Boire G, Larche M, Spiegel L, Schneider R, Laxer RM, Turvey S, Houghton K, Duffy K, Campillo S, Lang B, Ramsey S, Stringer E, LeBlanc C, Johnson N, Schmeling H, Bruns A, Shiff N, Berard RA, Levy D, Duffy C, Tucker L: Early Disease Course In A Prospective Juvenile Idiopathic Arthritis Cohort. Annals of Rheumatic Disease. (in press) Co-PA
Yeung RSM, Ferguson PJ: Is multisystem inflammatory syndrome in children on the Kawasaki syndrome spectrum? Journal of Clinical Investigation. 2020: 130(11):5681-5684. PA
Rezaei E, Hogan D, Trost B, Kusalik AJ, Benseler SM, Boire G, Cabral DA, Campillo S, Chedeville G, Chetaille A, Dancey P, Duffy C, Watanabe Duffy K, Ellsworth J, Gordon J, Guillet C, Guzman J, Houghton K, Huber AM, Jurencak R, Karananayake B, Lang B, Laxer RM, Morishita K, Muhajarine N, Oen KG, Petty RE, Ramsey SE, Roth J, Schneider R, Scuccimarri R, Spiegel L, Stringer E, Taylor-Gjevre R, Tse SM, Tucker LB, Tupper S, Turvey SE, Yeung RSM, Rosenberg AM for the BBOP Study Group: Clinical and associated inflammatory biomarker features predictive of short-term outcomes in non-systemic juvenile idiopathic arthritis. Rheumatology 2020: 59(9):2402-2411. C
Ennis D, Yeung RSM, Pagnoux C: Long-term use and remission of granulomatosis with polyangiitis with the oral C5a receptor inhibitor avacopan. BMJ Case Report 2020: 13(10):e236236. C
Henderson LA, Canna SW, Friedman KG, Gorelik M, Lapidus SK, Bassiri H, Behrens EM, Ferris A, Kernan KF, Schulert GS, Seo P, Son MBF, Tremoulet AH, Yeung RSM, Mudano AS, Turner AS, Karp DR, Mehta JJ: American College of Rheumatology clinical guidance for multisystem inflammatory syndrome in children associated with SARS-CoV-2 and hyperinflammation in pediatric COVID-19. Version 1. Arthritis and Rheumatology 2020: 72(11) 1791-1805. C
Tam H, El Tal T, Go E, Yeung RSM: Pediatric inflammatory multisystem syndrome temporally associated with COVID-19: a spectrum of diseases with many names. Canadian Medical Association Journal. 2020: 192(38):E1093-E1096. SRI
Chhabra A, Oen K, Huber AM, Shiff NJ, Boire G, Benseler SM, Berard RA, Scuccimarri R, Feldman BM, Lim LSH, Barsalou J, Bruns A, Cabral DA, Chedeville G, Ellsworth J, Houghton K, Lang B, Morishita K, Rumsey DG, Rosenberg AM, Tse SM, Duffy KW, Duffy CM, Guzman J, on behalf of ReACCh-Out Investigators: Real-world effectiveness of common treatment strategies for juvenile idiopathic arthritis: results from a Canadian cohort. Arthritis Care and Research 2020: 72(7): 897-906. C
Binnington B, Sakac D, Yi Q, Tong TN, Parmar N, Duong TT, Yeung RSM, Pendergrast J, Branch DR: Stability of 40 cytokines/chemokines in chronically ill patients under different storage conditions. Cytokine 2020: 130:155057. C
Downie ML, Manlhiot C, Latino GA, Collins TH, Chahal N, Yeung RSM, McCrindle BW. (2020). Subtypes of non-response to intravenous immunoglobulin in the acute treatment of Kawasaki disease: a matched case control study. Canadian Journal of Cardiology. Co-SRI
Barber CEH, Twilt M, Pham T, Currie GR, Benseler SM, Yeung RSM, Batthish M, Blanchette N, Guzman J, Lang B, LeBlanc C, Levy DM, O’Brien C, Schmeling H, Soon G, Spiegel L, Whitney K, Marshall DA: A Canadian evaluation framework for quality improvement in Childhood Arthritis: key performance indicators of the process of care. Arthritis Research and Therapy 2020: 22(1):53. C
Lee JJY, Eng SWM, Feldman BM, Guzman J, Oen K, Yeung RSM on behalf of the ReACCh-Out Consortium. (2020). Implications of adopting the newly proposed Pediatric Rheumatology International Trials Organization (PRINTO) classification criteria for JIA: Results from the Research in Arthritis in Canadian Children, emphasizing Outcomes (ReACCh-Out) Cohort. Arthritis and Rheumatology. 72: 3-6. SRI
Henrey A, Rypdal V, Rypdal M, Loughin T, Nordal E, Guzman J, on behalf of ReACCh-Out and NoSPeR Investigators: Validation of prediction models of severe disease course and non-achievement of remission in juvenile idiopathic arthritis part 2: results of the Nordic model in the Canadian cohort. Arthritis Research and Therapy 2020: 22(1):10. C
Batthish M, Berard RA, Cabral D, Bolaria R, Chedeville G, Duffy C, Gerhold K, Gerschman T, Huber A, Proulx-Gauthier JP, Rosenberg A, Rumsey D, Schmeling H, Shiff N, Soon G, Bruns A, Tucker L, Guzman J and the Canadian Alliance of Pediatric Rheumatology Investigators: A new Canadian inception cohort for juvenile idiopathic arthritis: the Canadian Alliance of Pediatric Rheumatology Investigators Registry. Rheumatology 2020: 59(10):2796-2805. C
Rumsey DG, Guzman J, Rosenberg AM, Huber AM, Scuccimarri R, Shiff NJ, Bruns A, Feldman BM, Eurich DT for the Research in Arthritis in Canadian Children Emphasizing Outcomes Investigators. (2019). Worse quality of life, function, and pain in children with enthesitis, irrespective of their juvenile arthritis category. Arthritis Care and Research. 72(3): 441-446. C
Sham L, Bitnum A, Branson H, Hazrati LN, Dell SD, Yeung RSM, Johnstone J, Yeh A: Treatment of rituximab-associated chronic CNS enterovirus using IVIG and fluoxetine. Neurology 2019: 92(19):916-918. C
Guzman J, Henrey A, Loughin T, Berard RA, Shiff NJ, Jurencak R, Huber AM, Oen K, Gerhold K, Feldman BM, Succimarri R, Houghton K, Chedeville G, Morishita K, Lang B, Dancey P, Rosenberg AM, Barsalou J, Bruns A, Watanabe Duffy K, Benseler SM, Duffy CM, Tucker LB, on behalf of ReACCh-Out Investigators: Predicting which children with juvenile idiopathic arthritis will not attain early remission with conventional treatment: results from the ReACCh-Out cohort. Journal of Rheumatology 2019: 46(6):628-635. C
Lee JJY, Duffy CM, Guzman J, Oen K, Barrowman N, Rosenberg AM, Shiff NJ, Stringer E, Spiegel L, Morishita KA, Lang B, Reddy D, Huber AM, Cabral DA, Feldman BM, Yeung RSM, Tucker LB, Watanabe DK; ReACCh-Out Investigators: Prospective determination of the incidence and risk factors of new-onset uveitis in juvenile idiopathic arthritis: the research in arthritis in Canadian children emphasizing outcomes cohort. Arthritis Care and Research 2019: 71(11):1436-1443. C
Gibson KM, Morishita KA, Dancey P, Moorehead P, Drogemoller B, Han X, Graham J, Hancock RE, Foell D, Benseler SM, Luqmani R, Yeung RSM, Shenoi S, Bohm M, Rosenberg AM, Ross CJ Cabral DA, Brown KL, PedVas investigators network: Identification of novel Adenosine Deaminase 2 gene variants and varied clinical phenotype in pediatric vasculitis. Arthritis Rheumatology 2019: 71(10): 1747-1755. C
Lee JJY, Alsaleem A, Chiang GPK, Limenis E, Sontichai W, Yeung RSM, Akikusa J, Laxer RM: Hallmark trials in ANCA-Associated Vasculitis (AAV) for the pediatric rheumatologist. Paediatric Rheumatology Online Journal 2019: 17(1)31. C
Grotenhuis HB, Aeschlimann FA, Hui W, Slorach C, Yeung RSM, Benseler SM, Bradley TJ, Grosse-Wortmann L: Increased arterial stiffness adversely affects left ventricular mechanics in patients with pediatric Takayasu Arteritis from a Toronto cohort. Journal of Clinical Rheumatology 2019: 25(4):171-175. C
Nagelkerke SQ, Tacke CEA, Breunis WB, Tanck MWT, Geissler J, Png E, Hoang L, van der Heijden J, Naim A, Yeung RSM, Levin M, Wright V, Burgner D, Ponsonby AL, Ellis J, Cimaz, Shimizu C, Burns JC, Fijnvandraat K, van der Schoot E, de Boer M, Davila S, Hibberd M and Kuijpers TW: Extensive ethnic variation and linkage disequilibrium at the FCGR2/3 locus: different genetic associations revealed in Kawasaki Disease. Frontiers in Immunology 2019: 10:185:1-16. C
Kip MMA, Currie G, Marshall DA, Grazziotin Lago G, Twilt M, Vastert SJ, Swart JF, Wulffraat N, Yeung RSM, Benseler SM, IJzerman MJ and on behalf of the UCAN CAN-DU Health Economics Working Group. Seeking the state of the art in standardized measurement of health care resource use and costs in juvenile idiopathic arthritis: a scoping review. Pediatric Rheumatology 2019: 17(1):20. C
Volpi S, Cicalese MP, Tuijnenburg P, Tool ATJ, Cuadrado E, Abu-Halaweh M, Ahanchian H, Alzyoud R, Akdemir ZC, Barzaghi F, Blank A, Boisson B, Bottino C, Brigida I, Caorsi R, Casanova JL, Chiesa S, Chinn IK, Duckers G, Enders A, Erichsen HC, Forbes LR, Gambin T, Gattorno M, Karimiani EG, Giliani S, Gold MS, Jacobsen EM, Jansen MH, King JR, Laxer RM, Lupski JR, Mace E, Marcenaro S, Maroofian R, Meijer AB, Niehues T, Notarangelo LD, Orange J, Pannicke U, Pearson C, Picco P, Quinn PJ, Schulz A, Seeborg F, Stray-Pedersen A, Tawamie H, van Leeuwen EMM, Aiuti A, Yeung RSM, Schwarz K, Kuijpers TW. A combined immunodeficiency with severe infections, inflammation and allergy caused by ARPC1B deficiency. The Journal of Allergy and Clinical Immunology 2019: 143(6):2296-2299. co-SRI
Eng SWM, Aeschlimann FA, van Veenendaal M, Berard RA, Rosenberg AM, Morris Q, Yeung RSM on behalf of the ReACCh-Out Research Consortium. Patterns of joint involvement in juvenile idiopathic arthritis and prediction of disease course: a prospective study with multilayer non-negative matrix factorization. PLOS Medicine 2019: 16(2):e1002750. SRI
Aeschlimann FA, Barra L, Alsolaimani R, Benseler SM, Hebert D, Khalidi N, Laxer RM, Noone D, Pagnoux C, Twilt M, Yeung RSM: Presentation and disease course of childhood-onset versus adult-onset Takayasu Arteritis. Arthritis Rheumatology 2018: 71(2):315-323. SRI
Lee JJY, Duffy CM, Guzman J, Oen K, Barrowman N, Rosenberg AM, Shiff NJ, Boire G, Stringer E, Spiegel L, Morishita KA, Lang B, Reddy D, Huber AM, Cabral DA, Feldman BM, Yeung RSM, Tucker LB, Watanabe Duffy K, ReACCh Out Investigators. The Research in Arthritis in Canadian Children Emphasizing Outcomes (ReACCh Out) Cohort: Prospective Determination of the Incidence of New Onset Uveitis in Juvenile Idiopathic Arthritis. Arthritis Care and Research 2018 Oct 15. doi: 10.1002/acr.23783. (Epub ahead of print) C
Da Silveira Cavalcante L, Branch DR, Duong TT, Yeung RSM, Acker JP, Holovati JL: The immune-stimulation capacity of liposome-treated red blood cells. Journal of Liposome Research 2018: 28(3):173-181. C
Kipkeu BJ, Shyian ML, da Silveira Cavalcante L, Duong TT, Yeung RSM, Binnington B, Branch DR, Acker JP, Holovati JL: Evaluation of the functional properties of cryopreserved buffy coat-derived monocytes for monocyte monolayer assay. Transfusion 2018: 58(8):2027-2035. C
Okihiro A, Hasija R, Fung L, Cameron B, Feldman BM, Laxer R, Schneider R, Silverman E, Spiegel L, Yeung RSM, Tse SML: Development of neoplasms in pediatric patients with rheumatic disease exposed to anti-tumor necrosis factor therapies: a single Centre retrospective study. Pediatric Rheumatology Online Journal 2018: 16(1):17. C
Arthur VL, Shuldiner E, Remmers EF, Hinks A, Grom A, Foel D, Martini A, Gattorno M, Ozen S, Prahalad S, Zeft AS, Bohnsack JF, Ilowite NT, Mellins ED, Russo R, Len C, Oliveira S, Yeung RSM, Rosenberg AM, Wedderburn LR, Anton J, Haas J-P, Rosen-Wolff A, Minden K, Szymanski AM, INCHARGE consortium, Thomson W, Kastner DL, Woo P, Ombrello MJ: IL1RN variation influences both disease susceptibility and response to human recombinant IL-1RA therapy in systemic juvenile idiopathic arthritis. Arthritis and Rheumatology 2018:7 0(8): 1319-1330. C
Hinks A, McMarion MC, Cobb J, Comeau ME, Sudman M, Ainsorth HC, Bowes J, Juvenile Arthritis Consortium for Immunochip, Becker ML, Bohnsack JF, Haas JP, Lovell DJ, Mellins ED, Nelson JL, Nordal E, Punaro M, Reed AM, Rose CD, Rosenberg AM, Rygg M, Smith SL, Stevens AM, Videm V, Wallace CA, Wedderburn LR, Yarwood A, Yeung RSM, Langefeld CD, Thompson SD, Thomson W, Prahalad S: The genetic profile of rheumatoid factor-positive polyarticular juvenile idiopathic arthritis (JIA) resembles that of adult rheumatoid arthritis (RA). Arthritis and Rheumatology 2018: 70(6): 957-962. C
Manlhiot C, Mueller B, O’Shea S, Majeed H, Bernknopf B, Labelle M, Westcott K, Heming B, Chahal N, Birken CS, Yeung RSM, McCrindle BW: Environmental epidemiology of Kawasaki Disease: linking disease etiology, pathogenesis and global distribution? PLOS ONE 2018: 13(2):e0191087. Co-SRI
Oen K, Guzman J, Dufault B, Tucker LB, Shiff NJ, Watanabe DK, Lee JJYJ, Feldman BM, Berard RA, Dancey P, Huber AM, Scuccimarri R, Cabral DA, Morishita KA, Ramsey SE, Rosenberg AM, Boire G, Benseler SM, Lang B, Houghton K, Miettunen PM, Chedeville G, Levy DM, Bruns A, Schmeling H, Haddad E, Yeung RSM, Duffy CM, Research in Arthritis in Canadian Children emphasizing Outcomes (ReACCh-Out) investigators: Health-related quality of life in an inception cohort of children with Juvenile Idiopathic Arthritis: a longitudinal analysis. Arthritis Care Research 2018: 70(1):134-144. co-SRI
Co-PI on CIHR Team grant leading to this publication and active participant in design of research question, data acquisition and analysis and manuscript preparation
Shiff NJ, Tupper S, Oen K, Guzman J, Lim H, Lee CH, Bryce R, Huber AM, Boire G, Dancey P, Feldman B, Laxer R, Miettunen P, Schemling H, Watanabe DK, Levy DM, Turvey S, Bolaria R, Bruns A, Cabral DA, Campillo S, Chedeville G, Feldman DE, Haddad E, Houghton K, Johnson K, Jurencak R, Lang B, Larche M, Morishita K, Ramsey S, Roth J, Schneider R, Scuccimarri R, Spiegel L, Stringer E, Tse SM, Yeung RSM, Duffy CM, Tucker LB: Trajectories of pain severity in juvenile idiopathic arthritis: results from the Research in Arthritis in Canadian Children Emphasizing Outcomes cohort. Pain 2018: 159(1):57-66. co-SRI
Noone D, Yeung RSM, Hebert D: Outcome of kidney transplantation in pediatric patients with ANCA-associated glomerulonephritis: a single-center experience. Pediatric Nephrology 2017: 32(12):2343-2350. C
Aeschlimann FA, Eng SWM, Sheikh S, Laxer RM, Hebert D, Noone D, Twilt M, Pagnoux C, Benseler SM, Yeung RSM: Childhood Takayasu arteritis: disease course and response to therapy. Arthritis Research and Therapy. Arthritis Research and Therapy 2017: 19(1):255. SRI
Guzman J, Kerr T, Ward LM, Ma J, Oen K, Rosenberg AM, Feldman BM, Boire G, Houghton K, Dancey P, Scuccimarri R, Bruns A, Huber AM, Watanabe Duffy K, Shiff NJ, Berard RA, Levy DM, Stringer E, Morishita K, Johnson N, Cabral DA, Larche M, Petty RE, Laxer RM, Silverman E, Miettunen P, Chetaille AL, Haddad E, Spiegel L, Turvey SE, Schmeling H, Lang B, Ellsworth J, Ramsey SE, Roth J, Campillo S, Benseler SM, Chedeville G, Schneider R, Tse SML, Bolaria R, Gross K, Feldman D, Cameron B, Jurencak R, Dorval J, LeBlanc C, St Cyr C, Gibbon M, Yeung RSM, Duffy CM, Tucker LB: Growth and weight gain in children with juvenile idiopathic arthritis: results from the ReACCh-Out cohort. Pediatric Rheumatology Online Journal 2017: 15(1):68. co-SRI
Aeschlimann FA, Yeung RSM, Laxer RM, Hebert D, Cooper A, Chami R, Noone D: A toddler presenting with pulmonary renal syndrome. Case Reports in Nephrology and Dialysis 2017: 7(2)73-80. C
Bonetto C, Trotta F, Felicetti P, Alarcon GS, Santuccio C, Bachtiar NS, Brauchli Pernus Y, Chandler R, Girolomoni G, Hadden RD, Kucuku M, Ozen S, Pahud B, Top K, Varrrichio O, Wise RP, Znoni G, Zivkovic S, Bonhoeffer J, Brighton Collaboration Vasculities Working Group: Vasculitis as an adverse event following immunization – systematic literature review. Vaccine 2016: 34(51):6641-6651. C
Downie ML, Manlhiot C, Collins TH, Chahal N, Yeung RSM, McCrindle BW: Factors associated with development of coronary artery aneurysms after Kawasaki disease are similar for those treated promptly and those with delayed or no treatment. International Journal of Cardiology 2017: 236:157-161. co-SRI
Felicetti P, Trotta F, Bonetto C, Santuccio C, Pernus YB, Burgner D, Chandler R, Girolomoni G, Hadden RDM, Kochar S, Kukucu M, Monaco G, Ozen S, Pahud B, Phuong L, Bachtiar NS, Teeba A, Top K, Varrichio F, Wise RP, Zanoni G, Zivkovic S, Bonhoeffer J, The Brighton Collaboration Vasculitis Working Group: Spontaneous reports of vasculitis as an adverse event following immunization: a descriptive analysis across three international databases. Vaccine 2017: 34(51):6634-6640. C
Kahr WH, Pluthero FG, Elkadri A, Warner N, Drobac M, Chen CH, Lo R, Li L, Li R, Li Q, Thoeni C, Pan J, Leung G, Lara-Corrales I, Murchie R, Cutz E, Laxer RM, Upton J, Roifman CM, Yeung RSM, Brumell JH, Muise AM: Loss of the Arp2/3 complex component ARPC1B causes platelet abnormalities and predisposes to inflammatory disease. Nature Communications 2017: 8:14816. C
Morishita K, Moorthy L, Lubieniecka J, Twilt M, Yeung RSM, Toth M, Shenoi S, Ristic G, Nielsen S, Li S, Lee T, Lawson E, Kostic M, Klein-Gitelman M, Huber A, Hersh A, Foell D, Elder M, Eberhard B, Dancey P, Charuvanij S, Benseler SM, Cabral D: Early outcomes in children with Antineutrophil Cytoplasmic Antibody (ANCA) Associated Vasculitis (AAV). Arthritis and Rheumatology 2017: 69(7): 1470-1479. C
Dhanrajani A, Yeung RSM: Revisiting the role of steroids and aspirin in the management of acute Kawasaki disease. Current Opinion in Rheumatology 2017: 29(5):547-552. SRI
Phuong LK, Bonetto C, Buttery J, Pernus YB, Chandler R, Felicetti P, Goldenthal KL, Kukucu M, Monaco G, Pahud B, Shulman ST, Top KA, Trotta F, Ulloa-Gutierrez R, Varricchio F, de Ferranti S, Newburger JW, Dahdah N, Singh S, Bonhoeffer J, Burgner D, The Brighton Collaboration Vasculitis Working Group: Kawasaki Disease and immunization: a systematic review. Vaccine 2017: 35(14):1770-1779. C
Hinks A, Bowes J, Cobb J, Ainsworth HC, Marion MC, Comeau ME, Sudman M, Han B, Juvenile Arthritis Consortium for Immunochip, Becker ML, Bohnsack JF, de Bakker PIW, Haas JP, Hazen M, Lovell DJ, Nigrovic PA, Nordal E, Punnaro M, Rosenberg AM, Rygg M, Smith SL, Wise CA, Videm V, Wedderburn LR, Yarwood A, Yeung RSM, Prahalad S, Langefeld CD, Raychaudhuri S, Thompson SD, Thomson W: Fine-mapping the MHC locus in juvenile idiopathic arthritis (JIA) reveals genetic heterogeneity corresponding to distinct adult inflammatory arthritic diseases. Annals of Rheumatic Diseases. Epub ahead of print doi: 10.1136/annrheumdis-2016-210025. C
Ombrello MJ, Arthur VL, Remmers EF, Hinks A, Tachmazidou I, Grom A, Foell D, Martini A, Gattorno M, Ozen S, Prahalad S, Zeft AS, Bohnsack JF, Illowite NT, Mellins ED, Russo R, Len C, Hilario MOE, Oliveira S, Yeung RSM, Rosenberg A, Wedderburn LR, et al Langefeld CD, Thompson S, Zeggini E, Kastner DL, Woo P, Thomson W: Genetic architecture distinguishes systemic juvenile idiopathic arthritis from other forms of juvenile idiopathic: clinical and therapeutic implications. Annals of Rheumatic Diseases 2017: 76(5):906-913. C
Barnabe C, Toepfer D, Marotte H, Hauge EM, Scharmga A, Kocijan R, Kraus S, Boutroy S, Schett G, Keller KK, deJong J, Stok KS, Finzel S, Yeung RSM and members of the SPECTRA collaboration: Definition for rheumatoid arthritis erosions imaged with high resolution peripheral quantitative computed tomography and interreader reliability for detection and measurement. The Journal of Rheumatology 2016: 43(10)1935-1940. C
Nagaraj S, Finzel S, Stok KS, Barnabe C, members of the SPECTRA collaboration (Yeung RSM member) collaboration: High-resolution peripheral quantitative computed tomography imaging in the assessment of periarticular bone of metacarpophalangeal and wrist joints. The Journal of Rheumatology 2016: 43(10)1921-1934. C
Aeschlimann FA, members of the SPECTRA collaboration (Yeung RSM member) collaboration: TNF vs IL-1 targeted treatment in Kawasaki Disease. Current Treatment Options in Rheumatology. 2016: 2:283-295. SRI
Alphone MP, Duong TT, Shumitzu C, Hoang TL, McCrindle BW, Franco A, Schurmans S, Philpott DJ, Hibberd ML, Burns J, Kuijpers TW, Yeung RSM: Inositol-Triphosphate 3-Kinase C mediates inflammasome activation and treatment response in Kawasaki disease. Journal of Immunology 2016: 197(9): 3481-3489. SRI
Shimizu C, Eleftherohorinou H, Wright VJ, Kim J, Alphone MP, Perry JC, Cimaz R, Burgner D, Dahdah N, Hoang LT, Khor CC, Salgado A, Tremoulet AH, Davila S, Kuijpers TW, Hibberd ML, Johnson TA, Takahashi A, Tsunoda T, Kubo M, Tanaka T, Onouchi Y, Yeung RSM, Coin LJM, Levin M, Burns JC on behalf of the International Kawasaki Disease Genetic Consortium: Genetic variation in the SLC8A1 calcium signaling pathway is associated with susceptibility to Kawasaki disease and coronary artery abnormalities. Circulation Cardiovascular Genetics 2016: 9(6): 559-568. C
Aeschlimann FA, Grosse-Wortmann L, Benseler SM, Laxer RM, Hebert D, Yeung RSM: Arterial dissection in childhood Takayasu Arteritis: not as rare as thought. Pediatric Rheumatology Online Journal 2016: 22:14(1): 56. SRI
Yeung RSM, S Albani, Feldman BM, Mellins E, Prakken B, Wedderburn L: Enhancing translational research in paediatric rheumatology through standardization. Nature Reviews Rheumatology 2016: 12(11): 684-690. PA
Guzman J, Oen K, Huber AM, Watanabe Duffy K, Boire G, Shiff N, Berard RA, Levy DM, Stringer E, Scuccimarri R, Morishita K, Johnson N, Cabral DA, Rosenberg AM, Larche M, Dancey P, Petty RE, Laxer RM, Silverman E, Miettunen P, Chetaille AL, Haddad E, Houghton K, Spiegel L, Turvey SE, Schmeling H, Lang B, Ellsworth J, Ramsey SE, Bruns A, Roth J, Campillo S, Benseler SM, Chedeville G, Schneider R, Tse SM, Bolaria R, Gross K, Feldman B, Feldman D, Cameron B, Jurencak R, Dorval J, LeBlanc C, St Cyr C, Gibbon M, Yeung RSM, Duffy CM, Tucker LB, ReACCh-Out investigators: The risk and nature of flares in juvenile idiopathic arthritis: results from the ReACCh-Out cohort. Annals of the Rheumatic Diseases 2016: 75(6): 1092-8. C
Cui A, Quon G, Rosenberg A, Yeung RSM, Morris QD: Gene expression deconvolution for uncovering molecular signatures in response to therapy in juvenile idiopathic arthritis. PLoS ONE 2016: May 31: 11(5):e0156055. Co-SRI
Sieberts SK, Zhu F, García-García J, Stahl E, Pratap A, Pandey G, Pappas D, Aguilar D, Anton B, Bonet J, ksi R, Fornés O, Guney E, Li H, Marín MA, Panwar B, Planas-Iglesias J, Poglayen D, Cui J, O Falcao A, Suver C, Hoff B, Balagurusamy VSK, Dillenberger D, Chaibub Neto S, Norman T, Aittokallio T, Azencott C, Bellón V, Boeva V, Bunte K, Chheda H, Cheng L, Corander J, Dumontier M, Goldenberg A, Gopalacharyulu P, Hajiloo M, Hidru D, Jaiswal A, Kaski S, Khalfaoui B, li Khan SA, Kramer ER, Marttinen P, Mezlini AM, Molparia B, Pirinen M, Saarela J, Samwald M, Stoven V, Tang H, Tang J, Torkamani A, Vert JP, Wang B, Wang T, Wennerberg K, Wineinger NE, Xiao G, Xie Y, Yeung RSM, Zhan X, Zhao C, Calaza M, Elmarakeby H, Heath LS, Long Q, Moore JD, Opiyo SO, Savage RS, Zhu J, Greenberg J, Kremer J, Michaud K, Barton A, Coenen M, Mariette X, Miceli C, Shadick N, Weinblatt M, de Vries N, Tak PP, Gerlag D, Huizinga TWJ, Kurreeman F, Allaart C, Bridges Jr SL, Criswell L, Moreland L, Klareskog L, Saevarsdottir S, Padyukov L, Gregersen PK, Friend S, Plenge R, Stolovitzky G, Oliva B, Guan Y, Mangravite LM, Rheumatoid Arthritis Challenge Consortium: Crowdsourced assessment of common genetic contribution to prediciting anti-TNF treatment response in rheumatoid arthritis. Nature Communications 2016: 7:12460. C
Downie ML, Manlhiot C, Latino GA, Collins TH, Chahal N, Yeung RSM, McCrindle BW: Variability in response to intravenous immunoglobulin in the treatment of Kawasaki disease. Journal of Pediatrics 2016: 179:124-130.e1. co-SRI
Cabral DA, Canter DL, Muscal E, Nanda K, Wahezi DM, Spalding SJ, Twilt M, Benseler SM, Campillo S, Charuvanij S, Dancey P, Eberhard BA, Elder ME, Hersh A, Higgins G, Huber AM, Khubchandani R, Kim S, Klein-Gitelman M, Kostic M, Lawson E, Lee T, Lubieniecka JM, McCurdy D, Moorth LN, Morishita KA, Nielsen SM, O’Neil KM, Reiff A, Ristic G, Robinson AB, Sarmineto A, Shenoi S, Toth MB, Van Mater H, Wagner-Weiner L, Weiss JE, White AJ, Yeung RSM, ARChiVe Investigators Network within the PedVas Initiative: Comparing presenting clinical features in 48 children with microscopic polyangiitis (MPA) against 183 having granulomatosis with polyangiitis (GPA). An ARChiVe study. Arthritis and Rheumatology 2016: 68(10):2514-26. C
Zeft AS, Burns JC, Yeung RSM, McCrindle BW, Newburger JW, Dominguez SR, Anderson MS, Arrington C, Shulman ST, Yoon J, Tewelde H, Mix C, Pope CA: Kawasaki disease and exposure to fine particulate air pollution. Journal of Pediatrics 2016: 177: 179-183.e1. C
Niaki OZ, Clarke AE, Ramsey-Goldman R, Yeung RSM, Hayward K, Oen K, Duffy CM, Rosenberg A, O’Neil KM, von Scheven E, Schanberg L, Labrecque J, Tse S, Hasija R, Lee JJYL, Bernatsky S: Malignancy incidence in 5,294 Juvenile Arthritis Patients. RMD Open, May 2016: May 2:2(1):e000212. C
Chan MO, Petty RE, Guzman J on behalf of the ReACCh-Out Investigators: A family history of psoriasis in a first-degree relative in children with JIA: to include or exclude? Journal of Rheumatology 2016: May 43(5):944-7. C
Ombrello MJ, Remmers EF, Tachmazidou I, Grom A, Foell D, Haas J-P, Martini A, Gattorno M, Ozen S, Prahalad S, Zeft AS, Bohnsack JF, Mellins ED, Ilowite NT, Russo R, Len C, Hilario MOE, Oliveira S, Yeung RSM, Rosenberg A, Wedderburn LR, Anton J, Schwarz T, Hinks A, Bilginer Y, Park J, Cobb J, Satorius C, Han B, Baskin E, Duerr R, Achkar JP, Kamboh MI, Kaufman K, Kottyan LC, Pinto D, Scherer SW, Alarcon-Riquelme ME, Docampo E, EStivill X, Gul A, British Society of Pediatric and Adolescent Rheumatology (BSPAR) study group, Childhood Arthritis Prospective Study (CAPS) group, Randomized Placebo Phase Study of Rilonacept in sJIA (RAPPORT) investigators, Sparks-Childhood Arthritis Response to Medication Study (CHARMS) group, Biologically Based Outcome Predictors in JIA (BBOP) group, de Bakker PIW, Raychaudhuri S, Langefeld CD, Thompson SD, Zeggini E, Thomson W, Kaster DL, Woo P on behalf of the International Childhood Arthritis Genetics INCHARGE Consortium: HLA-DRB1*11 and variants of the MHC class II locus are strong risk factors for systemic juvenile idiopathic arthritis. Proceedings of the National Academy of Sciences 2015: 29: 112(52) 15970-5. C
Guzman J, Oen K, Tucker LB, Huber AM, Shiff N, Boire G… Yeung RSM et al: Degenerative joint disease. Annals of the Rheumatic Diseases 2016: 74(10)1854-1860. C
Soliman M, Laxer R, Manson D, Yeung RSM, Doria AS: Imaging of systemic vasculitis in childhood. Pediatric Radiology 2015: 45(8): 1110-25. C
Guzman J, Oen K, Huber AM, Duffy KW, Boire G, Shiff N, Berard RA, Levy DM, Stringer E, Succimarri R, Morishita K, Johnson N, Cabral D, Rosenberg AM, Larche M, Dancey P, Petty RE, Laxer RM, Silverman E, Miettunen P, Chetaille A-L, Haddad E, Houghton K, Spiegel L, Turvey SE, Schmeling H, Lang B, Ellsworth J, Ramsey SE, Bruns A, Roth J, Campillo S, Benseler SM, Chedeville G, Schneider R, Tse SML, Bolaria R, Gross K, Feldman B, Feldman D, Cameron B, Jurencak R, Dorval J, LeBlanc C, St Cyr C, Gibbon M, Yeung RSM, Duffy C, Tucker LB, for the ReACCh-Out investigators: The Risk and Nature of Flares in Juvenile Idiopathic Arthritis: Results from the ReACCh-Out Cohort. Annals of Rheumatic Diseases 2015: 0: 1-7. C
Guzman J, Oen K, Tucker LB, Huber AM, Shiff N, Boire G, Scuccimarri R, Berard RA, Tse SM, Morishita K, Stringer E, Johnson N, Levy DM, Duffy KW Cabral DA, Rosenberg AM, Larche M, Dancey P, Petty RE, Laxer RM, Silverman E, Miettunen P, Chetaille AL, Haddad E, Houghton K, Spiegel L, Turvey SE, Schmeling H, Lang B, Ellsworth J, Ramsey S, Bruns A, Campillo S, Benseler SM, Chedeville G, Schneider R, Yeung RSM, Duffy CM for the ReACCh-Out investigators: The Outcomes of Juvenile Idiopathic Arthritis in Children Managed with Contemporary Treatments: Results from the ReACCh-Out cohort. Annals of Rheumatic Disease 2014: 74:(10) 1854-1860. Co-SRI
Berard RA, Tomlinson G, Li X, Oen K, Rosenberg A, Feldman B, Yeung RSM, Bombardier C: Description of active joint count trajectories in juvenile idiopathic arthritis. Journal of Rheumatology 2014: 41(12): 2466-73. co-SRI
Eng SWM, Duong TT, Rosenberg AM, Morris Q, Yeung RSM, REACCH OUT and BBOP research consortia: The biologic basis of clinical heterogeneity in juvenile idiopathic arthritis. on behalf of the REACCH OUT and BBOP Research Consortia. Arthritis and Rheumatology 2014: 66(12): 3463-75. SRI
Duvvuri B, Duvvuri VR, Wang C, Chen L, Wagar LE, Jamnik V Wu J, Yeung RSM, Grigull J, Watts TH, Wu GE. The human immune system recognizes neopeptides derived from mitochondrial DNA deletions. Journal of Immunology 2014: 192(10): 4581-91. C
Scuccimarri R, Yeung RSM: Kawasaki Disease: High Index of Suspicion Needed in a Febrile Child. Paediatrics and Child Health 2014: 19(5): pp 239-40. SRI
Ringold S, Weiss PF, Colbert RA, DeWitt EM, Lee T, Oen K, Prahalad S, Schneider R, Shenoi S, Vehe RK, Kimura Y, Juvenile Idiopathic Arthritis Research Committee of the Childhood Arthritis and Rheumatology Alliance. Childhood Arthritis and Rheumatology Alliance consensus treatment plans for new-onset polyarticular juvenile idiopathic arthritis. Arthritis Care and Research 2014: 66(7): pp 1063-72. C
Niedra E, Chahal N, Manlhiot C, Yeung RSM, McCrindle BW: Atorvastatin Safety in Kawasaki Disease Patients with Coronary Artery Aneurysms. Pediatric Cardiology 2014: 35(1): pp 89-92. C
LeBlanc CMA, Lang L, Bencivenga A, Chetaille AL, Dancey P, Dent P, Miettunen P, Oen K, Rosenberg A, Roth J, Scuccimarri R, Tse SML, Benseler SM, Cabral DA, Campillo S, Chedeville G, Duffy C, Duffy KW, Haddad E, Huber AM, Laxer R, Levy D, Johnson N, Ramsey S, Shiff N, Schmeling H, Scheneider R, Stringer E, Yeung RSM, Tucker LB. Access to Biologic Therapies in Canada for Children with Juvenile Idiopathic Arthritis. Journal of Rheumatology 2012: 39: 9: pp 1875-9. C
Luca NJ, Yeung RSM: Epidemiology and management of Kawasaki Disease. Drugs 2012: 72: 8: pp 1029-38. SRI
Banks L, Lin YT, Chahal N, Manlhiot C, Yeung RSM, McCrindle BW: Factors Associated with Low Moderate-to-Vigorous Physical Activity Levels in Pediatric Patients with Kawasaki Disease. Clinical Pediatrics 2012: 51: 9: pp 828-834. C
Chahal N, Somji Z, Manlhiot C, Clarizia N, Ashley J, Yeung RSM, McCrindle B: Rate, Associated Factors and Outcomes of Recurrence of Kawasaki Disease in Ontario, Canada. Pediatrics International 2012: 54: 3: pp 383-7. C
Manlhiot C, Christie E, McCrindle BW, Rosenberg H, Chahal N, Yeung RSM: Complete and Incomplete Kawasaki Disease: two sides of the same coin. European Journal of Pediatrics 2012: 171: 4: pp 657-662. SRI
Millar K, Manlhiot C, Yeung RSM, Somji Z, McCrindle BW: Corticosteroid administration for patients with coronary artery aneurysms after Kawasaki disease may be associated with impaired regression. International Journal of Cardiology 2012: 154: 1: pp 9-13. C
Khor CC, Davila S, Breunis WB, Lee YC, Shimizu C, Wright V, Yeung RSM, Tan DE, Sim KS, Wang JJ, Wong TY, Pang J, Mitchell P, Cimaz R, Dahdah N, Cheung YF, Huang GY, Yang W, Park IS, Lee JJYK, Wu JY, Levin M, Burns JC, Burgner D, Kuijpers TW, Hibberd ML on behalf of the Hong Kong-Shanghai, Korean, Taiwan, U.S. and International, Kawasaki Disease Genetics Consortiums. Genome-wide association study identifies FCGR2A as a susceptibility locus for Kawasaki disease. Nature Genetics. 2011: 43: 12: pp 1241-6. C
Sleeper LA, Minich LL, McCrindle BM, Li JS, Mason W, Colan SD, Atz AM, Printz BF, Baker A, Vetter VL, Newburger JW: Evaluation of Kawasaki disease risk–scoring systems for intravenous immunoglobulin resistance. Pediatric Heart Network Investigators. Journal of Pediatric 2011: 158: 5: pp 831-835.e3. C
Blankier S, McCrindle BM, Ito S, Yeung RSM: The role of atorvastatin in regulating the immune response in a model of Kawasaki Disease. Clinical and Experimental Immunology 2011: 164: 2: pp 193-201. SRI
Alvira CM, Guignabert C, Kim YM, Wang L, Duong TT, Yeung RSM, Li DY, Mecham RP, Rabinovitch M: Inhibition of transforming growth factor-beta worsens elastin degradation in a murine model of Kawasaki disease. American Journal of Pathology 2011: 178: 3: pp 1210-20. C
Shiff NJ, Tucker L, Guzman J, Oen K, Yeung RSM, Duffy C: Factors Associated with a Longer Time to Access Pediatric Rheumatologists in Canadian Children with Juvenile Idiopathic Arthritis. The Journal of Rheumatology 2010: 37: 11: pp 2415-2421. C
Lin YT, Manlhiot C, Ching JCY, Han RK, Nield LE, Dillenburg R, Pepelassis D, Lai LS, Smythe J, Chahal N, Yeung RSM, McCrindle BW. Repeated Systematic Surveillance of Kawasaki Disease in Ontario from 1995 to 2006. Pediatrics International 2010: 52: 5: pp 699-706. C
Yeung RSM: Kawasaki Disease: update on pathogenesis. Current Opinion in Rheumatology 2010: 22: pp 551-560. PA
Oen K.; Duffy C; Tse S, Ramsey S Ellsworth J, Chedeville G, Chetaille AL St. Cyr, C, Cabral D, Spiegel L, Schneider R, Lang B, Huber A, Dancey P, Silverman E, Rosenberg AM, Cameron B, Johnson N, Dorval J, Scuccimarri R Campillo S, Petty RE, Duffy K, Boire G, Haddad E, Houghton K, Laxer RM, Turvey S, Miettunen P, Gross K, Guzman J, Benseler SM, Feldman B, Cheang M, Espinosa V, Yeung RSM, Tucker L. Early outcomes and improvement of patients with juvenile idiopathic arthritis enrolled in a Canadian multicentre inception cohort. Arthritis Care & Research 2010: 62: 4: 527-36. co-SRI
Manlhiot C, Yeung RSM, Chahal C, McCrindle BW: Intravenous immunoglobulin preparation type: association with outcomes for patients with acute Kawasaki disease. Pediatric Allergy and Immunology 2010: 21: 3: pp 515-21. C
Latino GA, Manlhiot C, Yeung RSM, Chahal C, McCrindle BW: Macrophage Activation Syndrome in the Acute Phase of Kawasaki Disease. Journal of Pediatric Haematology Oncology 2010: 32: 7: pp 527-31. C
Chahal N, Clarizia N, McCrindle B, Boydell K, Obadia M, Manlhiot C, Dillenburg R, Yeung RSM. Parental Anxiety Associated with Kawasaki Disease in Previously Healthy Children. Journal of Pediatric Health Care 2010: 24: 4: pp 250-7. SRI
Sabharwal T, Manlhiot C, Benseler SM, Tyrrell P, Chahal N, Yeung RSM, McCrindle BW: Comparison of Factors Associated with Coronary Artery Dilation Only Versus Coronary Artery Aneurysms in Patients with Kawasaki Disease. American Journal of Cardiology 2009: 104: 12: pp 1743-1747. Co-SRI
Oen K, Tucker L, Huber A, Miettunen P, Succimarri R, Campillo S, Cabral D, Feldman B, Tse S, Chedeville G, Spiegel L, Schneider R, Lang B, Ellsworth J, Ramsey S, Dancey P, Silverman E, Chetaille A-L, Rosenberg AM, Johnson N, Dorval J, Petty RE, Duffy K, Malleson P, Boire G, Hadad E, Houghton K, Laxer RM, St. Cyr C, Turvey S, Gross K, Guzman J, Benseler SM, Gibbon M, Cheang M, Espinosa V, Meshefedian G, Yeung RSM, Duffy C: Predictors of Early Inactive Disease in a Juvenile Idiopathic Arthritis Cohort: The Research in Arthritis in Canadian Children Outcomes Studies I. Arthritis Care and Research 2009: 61: 8: pp 1077-1086. Co-SRI
Manlhiot C, Yeung RSM, Clarizia NA, Chahal N, McCrindle BW: Kawasaki Disease at the Extremes of the Age Spectrum: Similar Outcomes, Different Associated Factors. Pediatrics 2009: 124: 3: pp e409-e415. C
Lau AC, Duong TT, Ito S, Wilson GJ, Yeung RSM: Inhibition of MMP-9 Activity Improves Coronary Outcome in an Animal Model of Kawasaki Disease. Clinical and Experimental Immunology 2009: 157: 2: pp 300-9. SRI
Lau AC, Duong TT, Ito S, Yeung RSM: Intravenous Immunoglobulin and Salicylate Differentially Modulate Pathogenic Processes Leading to Vascular Damage in Kawasaki Disease. Arthritis and Rheumatism 2009: 60: 7: pp 2131-41. SRI
Baker AL, Lu M, Minich LL, Atz AM, Klein GL, Korsin R, Lambert L, Li JS, Mason W, Radojewski E, Vetter VL, Newburger JW, et al: Pediatric Heart Network Investigators. Associated symptoms in the ten days before diagnosis of Kawasaki disease. Journal of Pediatrics 2009: 154(4): pp 592-595. C
Crystal MA, Syan SK, Yeung RSM, Smallhorn JF, McCrindle BW: Echocardiographic and Electrocardiographic Trends in Children with Acute Kawasaki Disease. Canadian Journal of Cardiology 2008: 24: pp 776-80. C
Crystal MA, Manlhiot C, Yeung RSM, Smallhorn JF, McCrindle BW: Coronary Artery Dilation After Kawasaki Disease for Children within the Normal Range. International Journal of Cardiology 2008: 136: 1: pp 27-32. C
Matheson LA, Duong TT, Rosenberg AM, Yeung RSM: Assessment of sample collection and storage methods for multicenter immunologic research in children. Journal of Immunological Methods 2008: 339: pp 82-89. SRI
Lau A, Duong TT, Ito S, Yeung RSM: Matrix Metalloproteinase-9 Activity Leads to Elastin Breakdown in an Animal Model of Kawasaki Disease. Arthritis and Rheumatism 2008: 58: 3: pp 854-63. SRI
Stringer E, Yeung RSM: Pathogenesis of Kawasaki disease: the central role of TNF-a. Future Rheumatology 2008: 3: pp 69-77. SRI
Stinson J, Toomey P, Stevens B, Kagan S, Duffy C, Huber A, Malleson P, McGrath P, Yeung RSM, Feldman, B: Asking the Experts: Exploring the Self-management Needs of Adolescents with Arthritis. Arthritis Care and Research 2008: 59: 65-72. C
Yeung RSM: Lessons Learned from an Animal Model of Kawasaki Disease. Clinical and Experimental Rheumatology 2007: (1 Supplement 44):S69-71. PA
Lau A, Rosenberg H, Duong TT, McCrindle BW, Yeung RSM: Elastolytic Matrix Metalloproteinases and Coronary Outcome in Children with Kawasaki Disease. Pediatric Research 2007: 61: 6: pp 710-5. SRI
Uziel Y, Feldman BM, Krafchik BR, Laxer RM, Yeung RSM: Increased serum levels of TGFb1 in children with localized scleroderma. Pediatric Rheumatology 2007: 5: pp 22. SRI
Newburger JM, Sleeper LA, McCrindle BW, Minich LL, Gersony W, Vetter VL, Atz AM, Li JS, Takahashi M, Baker AL, Colan SD, Mitchell PD, Klein GL, Sundel RP: Pediatric Heart Network Investigators. Randomized trial of pulsed corticosteroid therapy for primary treatment of Kawasaki disease. New England Journal of Medicine 2007: 356: pp 663-75. C
Yeung RSM: Phenotype and Coronary Outcome in Kawasaki Disease. The Lancet 2007: 369: pp 85-88. PA
Lang B, Yeung RSM, Oen K, Malleson P, Huber A, Riley M, Ebbeson R, Ramsey S, Laxer R, Silverman ED, McCrindle B, Ratnapalan S, Feldman BM: Corticosteroid Treatment of Refractory Kawasaki Disease. The Journal of Rheumatology 2006: 33(4): pp 803-808. CPA
Hui-Yuen JS, Duong TT, Yeung RSM: TNF-alpha is necessary for induction of coronary artery inflammation and aneurysm formation in an animal model of Kawasaki disease. The Journal of Immunology 2006: 176(10): pp 6294-6301. SRI
Cabral DA, Laxer RM, Schrader J, Turvey S, Stevens A, Yeung RSM, Foster HE, Emery H, Prendiville J, Tucker LB, Foeldvari I, Sherry DD, Klinkhoff AB, Wallace CA, Houghton K: Old Challenges and New Directions in Pediatric Rheumatology. Journal of Rheumatology 2006: 33: pp 173-84. C
Gong GWK, McCrindle BW, Ching JC, Yeung RSM: Arthritis presenting during the acute phase of Kawasaki disease. Journal of Pediatrics 2006: 148: pp 800-5. SRI
Benseler SM, McCrindle BW, Wong J, Tyrrell P, Silverman ED, Yeung RSM: Infections and Kawasaki Disease: Implications for Coronary Artery Outcome. Pediatrics 2005: 116: pp 760-766. SRI
Yeung RSM: Pathogenesis and Treatment of Kawasaki’s Disease. Current Opinion in Rheumatology 2005: 17 (5): pp 617-623. PA
Yeung RSM: Bones, Blood Vessels and the Immune System: What’s the link? Journal of Rheumatology 2005: 32: pp 2072-2075. PA
Yeung RSM: Kawasaki Disease: An Update. Hong Kong Journal of Pediatrics 2005: 10: pp 238-244. PA
Levy D, Silverman ED, McCrindle BW, Yeung RSM: Longterm outcomes in patients with Giant Aneurysms Secondary to Kawasaki Disease. Journal of Rheumatology 2005: May 2005: pp 928-934. SRI
Yeung RSM: The Etiology of Kawasaki Disease – A Superantigen-Mediated Process. Progress in Pediatric Cardiology 2004: 19: pp 109-113. PA
Wong D, Nutting A, Yeung RSM, McCrindle BW: Kawasaki Disease and Scald Injuries: A Possible Association. Journal of Cardiology 2004: 31: pp 1147-1149. C
Chan WC, Duong TT, Yeung RSM: Presence of IFN-gamma does not indicate its necessity for induction of coronary arteritis in a animal model of Kawasaki Disease. Journal of Immunology 2004: 173: pp 3492-3503. SRI
Yeung RSM: The Osteoprotegerin/Osteoprotegerin Ligand Family: Role in Inflammation and Bone Loss. Journal of Rheumatology 2004: 31: pp 844-846. PA
Duong TT, Silverman ED, Bissessar M, Yeung RSM: Superantigenic activity is responsible for induction of coronary arteritis in mice: An animal model of Kawasaki disease. International Immunology 2003: 15: pp 79-89. SRI
Huber A, Lam P-Y, Duffy C, Yeung RSM, Ditchfield M, Laxer D, Cole W, Graham H, Allen R, Laxer RM: Chronic Recurrent Multifocal Osteomyelitis: Clinical Outcomes After More Than Five Years of Follow-Up. Journal of Pediatrics 2002: 141: pp 198-203. C
Tse SML, Silverman ED, McCrindle BW, Yeung RSM: Early treatment with intravenous immunoglobulin in patients with Kawasaki disease. Journal of Pediatrics 2002: 140: pp 450-455. SRI
Uziel Y, Laxer RM, Krafchik BR, Yeung RSM, Feldman BM: Children with morphea have normal self-perception. Journal of Pediatrics 2000: 137: pp 727-730. C
Honkanen V, Silverman ED, Kumar A, Myones BL, Taylor G, Yeung RSM: TNFa production by T cells and macrophages in response to Lactobacillus cell wall extract. Pediatric Research 2000: 47: pp 561. SRI
Uziel Y, Feldman BM, Krafchik BR, Yeung RSM, Laxer RM: Methotrexate and corticosteriod therapy for pediatric localized scleroderma. Journal of Pediatrics 2000: 136: pp 91-95. C
Bachmaier K, Neu N, Yeung RSM, Mak T W, Liu P, Penninger J: Generation of Humanized Mice Susceptible to Peptide-Induced Inflammatory Heart Disease. Circulation 1999: 99: pp 1885-1891. C
Yeung RSM, Mak TW: Of Men in Mice: Using Murine Expression of Human MHC Molecules to Unravel Autoimmunity. The Immunologist 1998: 6: pp 209-213. PA
Yeung RSM, Penninger J, Khoo W, Kroemer G, Mak TW: Human CD4 and Human MHC Class II (DQ6) Transgenic Mice: Super-sensitivity to Superantigen-Induced Septic Shock. European Journal of Immunology 1996: 26: pp 1074-1082. PA
Yeung RSM, Penninger J, Kundig TM, Law Y, Yamamoto K, Kamikawaji N, Burkly L, Sasazuki T, Flavell RA, Ohashi PS, Mak TW: Human CD4-Major Histocompatiblity Complex Class II (DQw6) Transgenic Mice in an Endogenous CD4/CD8 Deficient Background: Reconstitution of Phenotype and Human-Restricted Function. Journal of Experimental Medicine 1994: 180: pp 1911-1920. PA
Yeung RSM, Penninger J, Tak TW: T-Cell Development and Function in Gene-Knockout Mice. Current Opinion in Immunology 1994: 6: pp 298-307. PA
Sebzda E, Wallace VA, Mayer J, Yeung RSM, Mak TW, Ohashi PS: Positive and Negative Thymocyte Selection Induced by Different Concentrations of a Single Peptide. Science 1994: 263: pp 1615-1618. C
Yeung RSM, Penninger J, Mak TW: Genetically modified animals and immunodeficiency. Current Opinion in Immunology 1993: 5: pp 585-594. PA