{"id":193,"date":"2015-10-30T00:36:46","date_gmt":"2015-10-30T00:36:46","guid":{"rendered":"https:\/\/lab.research.sickkids.ca\/trimble\/?page_id=193"},"modified":"2015-11-09T23:34:12","modified_gmt":"2015-11-09T23:34:12","slug":"primary-cilia-research","status":"publish","type":"page","link":"https:\/\/lab.research.sickkids.ca\/trimble\/research-2-2\/primary-cilia-research\/","title":{"rendered":"Primary Cilia"},"content":{"rendered":"

\"Primary<\/a>The primary cilium is a central signaling structure, likened to the cellular \u201cantenna\u201d, found on most cells of the body. Defects in cilia formation lead to a range of diseases and ongoing studies are aimed at investigating how cilia are formed, what controls their length, and how this is associated with their signal transduction activities.\u00a0 For these studies we are using cell culture and animal models including mice and zebrafish.<\/span><\/p>\n","protected":false},"excerpt":{"rendered":"

The primary cilium is a central signaling structure, likened to the cellular \u201cantenna\u201d, found on most cells of the body. Defects in cilia formation lead to a range of diseases and ongoing studies are aimed at investigating how cilia are formed, what controls their length, and how this is associated with their signal transduction activities.\u00a0…<\/p>\n","protected":false},"author":46,"featured_media":0,"parent":159,"menu_order":0,"comment_status":"closed","ping_status":"closed","template":"","meta":{"footnotes":""},"class_list":["post-193","page","type-page","status-publish","hentry","description-off"],"yoast_head":"\nPrimary Cilia - Trimble Lab<\/title>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/lab.research.sickkids.ca\/trimble\/research-2-2\/primary-cilia-research\/\" \/>\n<meta property=\"og:locale\" content=\"en_US\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"Primary Cilia\" \/>\n<meta property=\"og:description\" content=\"The primary cilium is a central signaling structure, likened to the cellular \u201cantenna\u201d, found on most cells of the body. Defects in cilia formation lead to a range of diseases and ongoing studies are aimed at investigating how cilia are formed, what controls their length, and how this is associated with their signal transduction activities.\u00a0…\" \/>\n<meta property=\"og:url\" content=\"https:\/\/lab.research.sickkids.ca\/trimble\/research-2-2\/primary-cilia-research\/\" \/>\n<meta property=\"og:site_name\" content=\"Trimble Lab\" \/>\n<meta property=\"article:modified_time\" content=\"2015-11-09T23:34:12+00:00\" \/>\n<meta property=\"og:image\" content=\"https:\/\/lab.research.sickkids.ca\/trimble\/wp-content\/uploads\/sites\/37\/2015\/11\/Primary-Cilia2.jpg\" \/>\n\t<meta property=\"og:image:width\" content=\"240\" \/>\n\t<meta property=\"og:image:height\" content=\"240\" \/>\n\t<meta property=\"og:image:type\" content=\"image\/jpeg\" \/>\n<meta name=\"twitter:card\" content=\"summary_large_image\" \/>\n<script type=\"application\/ld+json\" class=\"yoast-schema-graph\">{\"@context\":\"https:\/\/schema.org\",\"@graph\":[{\"@type\":\"WebPage\",\"@id\":\"https:\/\/lab.research.sickkids.ca\/trimble\/research-2-2\/primary-cilia-research\/\",\"url\":\"https:\/\/lab.research.sickkids.ca\/trimble\/research-2-2\/primary-cilia-research\/\",\"name\":\"Primary Cilia - Trimble Lab\",\"isPartOf\":{\"@id\":\"https:\/\/lab.research.sickkids.ca\/trimble\/#website\"},\"primaryImageOfPage\":{\"@id\":\"https:\/\/lab.research.sickkids.ca\/trimble\/research-2-2\/primary-cilia-research\/#primaryimage\"},\"image\":{\"@id\":\"https:\/\/lab.research.sickkids.ca\/trimble\/research-2-2\/primary-cilia-research\/#primaryimage\"},\"thumbnailUrl\":\"https:\/\/lab.research.sickkids.ca\/trimble\/wp-content\/uploads\/sites\/37\/2015\/11\/Primary-Cilia2.jpg\",\"datePublished\":\"2015-10-30T00:36:46+00:00\",\"dateModified\":\"2015-11-09T23:34:12+00:00\",\"breadcrumb\":{\"@id\":\"https:\/\/lab.research.sickkids.ca\/trimble\/research-2-2\/primary-cilia-research\/#breadcrumb\"},\"inLanguage\":\"en-US\",\"potentialAction\":[{\"@type\":\"ReadAction\",\"target\":[\"https:\/\/lab.research.sickkids.ca\/trimble\/research-2-2\/primary-cilia-research\/\"]}]},{\"@type\":\"ImageObject\",\"inLanguage\":\"en-US\",\"@id\":\"https:\/\/lab.research.sickkids.ca\/trimble\/research-2-2\/primary-cilia-research\/#primaryimage\",\"url\":\"https:\/\/lab.research.sickkids.ca\/trimble\/wp-content\/uploads\/sites\/37\/2015\/11\/Primary-Cilia2.jpg\",\"contentUrl\":\"https:\/\/lab.research.sickkids.ca\/trimble\/wp-content\/uploads\/sites\/37\/2015\/11\/Primary-Cilia2.jpg\"},{\"@type\":\"BreadcrumbList\",\"@id\":\"https:\/\/lab.research.sickkids.ca\/trimble\/research-2-2\/primary-cilia-research\/#breadcrumb\",\"itemListElement\":[{\"@type\":\"ListItem\",\"position\":1,\"name\":\"Home\",\"item\":\"https:\/\/lab.research.sickkids.ca\/trimble\/\"},{\"@type\":\"ListItem\",\"position\":2,\"name\":\"Research 2\",\"item\":\"https:\/\/lab.research.sickkids.ca\/trimble\/research-2-2\/\"},{\"@type\":\"ListItem\",\"position\":3,\"name\":\"Primary Cilia\"}]},{\"@type\":\"WebSite\",\"@id\":\"https:\/\/lab.research.sickkids.ca\/trimble\/#website\",\"url\":\"https:\/\/lab.research.sickkids.ca\/trimble\/\",\"name\":\"Trimble Lab\",\"description\":\"Cell Biology\",\"potentialAction\":[{\"@type\":\"SearchAction\",\"target\":{\"@type\":\"EntryPoint\",\"urlTemplate\":\"https:\/\/lab.research.sickkids.ca\/trimble\/?s={search_term_string}\"},\"query-input\":{\"@type\":\"PropertyValueSpecification\",\"valueRequired\":true,\"valueName\":\"search_term_string\"}}],\"inLanguage\":\"en-US\"}]}<\/script>\n<!-- \/ Yoast SEO Premium plugin. -->","yoast_head_json":{"title":"Primary Cilia - Trimble Lab","robots":{"index":"index","follow":"follow","max-snippet":"max-snippet:-1","max-image-preview":"max-image-preview:large","max-video-preview":"max-video-preview:-1"},"canonical":"https:\/\/lab.research.sickkids.ca\/trimble\/research-2-2\/primary-cilia-research\/","og_locale":"en_US","og_type":"article","og_title":"Primary Cilia","og_description":"The primary cilium is a central signaling structure, likened to the cellular \u201cantenna\u201d, found on most cells of the body. 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