{"id":163,"date":"2017-10-04T17:42:53","date_gmt":"2017-10-04T17:42:53","guid":{"rendered":"http:\/\/localhost\/wordpress\/molecular-analysis\/?page_id=163"},"modified":"2026-01-06T17:39:31","modified_gmt":"2026-01-06T17:39:31","slug":"publications","status":"publish","type":"page","link":"https:\/\/lab.research.sickkids.ca\/sparc-molecular-analysis\/publications\/","title":{"rendered":"Publications"},"content":{"rendered":"

[vc_row][vc_column][vc_column_text]<\/p>\n

\n

SPARC Selected Co-authored Publications<\/strong><\/h4>\n<\/div>\n

Proteomic Characterization of a Candidate Polygenic Driver of Metabolism in Non-small Cell Lung Cancer<\/a>
\nJournal of Molecular Biology. 2022.<\/span>
\nBadr, H., Blutrich, R., Chan, K., Tong, J., Taylor, P., Zhang, W., Kafri, R., R\u00f6st H.L., Tsao, M., Moran, M.F.<\/span><\/p>\n

 <\/p>\n

Integrative analysis of non-small cell lung cancer patient-derived xenografts identifies distinct proteotypes associated with patient outcomes<\/a>
\nNature Communications. 2022.<\/span>
\nMirhadi, S., Tam, S., Li, Q., Moghal, N., Pham, N., Tong, J., Golbourn, B.J., Krieger, J.R., Taylor, P., Li, M., Weiss, J., Martins-Filho, S.N., Raghavan, V., Mamatjan, Y., Khan, A.A., Cabanero, M., Sakashita, S., Huo, K., Agnihotri, S., Ishizawa, K., Waddell, T.K., Zadeh, G., Yasufuku, K., Liu, G., Shepherd, F.A., Moran, M.F., Tsao, M.<\/span><\/p>\n

 <\/p>\n

Mitochondrial Aconitase ACO2<\/sub> Links Iron Homeostasis with Tumorigenicity in Non-Small Cell Lung Cancer<\/a>
\nMolecular Cancer Research. 2023.<\/span>
\nMirhadi, S., Zhang, Z., Pham, N., Karimzadeh, F., Pintilie, M., Tong, J., Taylor, P., Krieger, J., Pitcher, B., Sykes, J., Wybenga-Groot, L.E., Fladd, C., Xu, J., Wang, T., Cabanero, M., Li, M., Weiss, J., Sakashita, S., Zaslaver, O., Yu, M., Caudy, A.A., St-Pierre, J., Hawkins, C., Kislinger, T., Liu, G., Shepherd, F.A., Tsao, M., Moran, M.F.<\/span><\/p>\n

 <\/p>\n

Sleuthing biochemical evidence to elucidate unassigned electron density in a CBL-SLAP2 crystal complex<\/a><\/p>\n

Structural Biology Communications. 2021.<\/span>
\nWybenga-Groot, L.E., McGlade, C.J.<\/span><\/p>\n

 <\/p>\n

SLAP2 Adaptor Binding Disrupts c-CBL Autoinhibition to Activate Ubiquitin Ligase Function<\/a>
\nJournal of Molecular Biology. 2021.<\/span>
\nWybenga-Groot, L.E., Tench, A.J., Simpson, C.D., St. Germain, J., Raught, B., Moran, M.F., McGlade, C.J.<\/span><\/p>\n

 <\/p>\n

Numb exon 9 inclusion regulates Integrin\u03b25 surface expression and promotes breast cancer metastasis<\/a>
\nNature Communications. 2022.<\/span>
\nZhang, Y., Dho, S.E., Othman, K., Simpson, C.D., Lapierre, J., Bondoc, A., McGlade, J.<\/span><\/p>\n

 <\/p>\n

SPARC Acknowledged Publications<\/strong><\/h4>\n

Proteome and secretome profiling of zinc availability in Cryptococcus neoformans identifies Wos2 as a subtle influencer of fungal virulence determinants<\/a>
\nBMC Microbiology. 2021.<\/span>
\nBall, B., Woroszchuk, E., Sukumaran, A., West, H., Afaq, A., Carruthers-Lay, D., Muselius, B., Gee, L., Langille, M., Pladwig, S., Kazi, S., Hendriks, A., Geddes-McAlister, J.<\/span><\/p>\n

 <\/p>\n

A designer peptide against the EAG2-Kv\u03b22 potassium channel targets the interaction of cancer cells and neurons to treat glioblastoma<\/a>
\nNature Cancer. 2023.<\/span>
\nDong, W., Fekete, A., Chen, X., Liu, H., Beilhartz, G.L., Chen, X., Bahrampour, S., Xiong, Y., Yang, Q., Zhao, H., Kong, T., Morioka, M.S., Jung, G., Kim, J., Schramek, D., Dirks, P.B., Song, Y., Kim, T., He., Y., Wanggou, S., Li, X., Melnyk, R.A., Wang, L., Huang, X.<\/span><\/p>\n

 <\/p>\n

Differential protein abundance in the regenerating Caribbean corallimorpharian Ricordea florida<\/a>
\nJournal of Zoo and Aquarium Research<\/span>
\nHorricks, R., Millar, Z., Sykes, K., Lumsden, J.<\/span><\/p>\n

 <\/p>\n

Loss of mfsd8 alters the secretome during Dictyostelium aggregation<\/a>
\nEuropean Journal of Cell Biology. 2023.<\/span>
\nHuber, R.J., Gray, J., Kim, W.D.<\/span><\/p>\n

 <\/p>\n

Proteomic profiling reveals engineered chitosan nanoparticles mediated cellular crosstalk and immunomodulation for therapeutic application in apical periodontitis<\/a>
\nBioActive Materials. 2022.<\/span>
\nHussein, H., Kishen, A.<\/span><\/p>\n

 <\/p>\n

TRPV4<\/sub> regulates \u03b21 integrin-mediated cell-matrix adhesions and collagen remodeling<\/a>
\nFederation of American Societies for Experimental Biology. 2023.<\/span>
\nJi, C., Wang, Y., Wang, Q., Wang, A., Ali, A., McCulloch, C.A.<\/span><\/p>\n

 <\/p>\n

A Proteomics Analysis of Calmodulin-Binding Proteins in\u00a0Dictyostelium discoideum<\/i>\u00a0during the Transition from Unicellular Growth to Multicellular Development<\/a>
\nInternational Journal of Molecular Sciences. 2021.<\/span>
\nKim, W.D., Yap, S.Q., Huber, R.B.<\/span><\/p>\n

 <\/p>\n

Coordination of metal center biogenesis in human cytochrome c oxidase<\/a>
\nNature Communications. 2022.<\/span>
\nN\u00fdvltov\u00e1, E., Dietz, J.V., Seravalli, J., Khalimonchuk, O., Barrientos, A.<\/span><\/p>\n

 <\/p>\n

Germination alters the microstructure, in vitro protein digestibility, \u03b1-glucosidase and dipeptidyl peptidase-IV inhibitory activities of bioaccessible fraction of pigeon pea (Cajanus cajan<\/i>) seeds<\/a>
\nLegume Sciences. 2021.<\/span>
\nOhanenye, I.C., Sun, X., Sarteshnizi, R.A., Udenigwe, C.C.<\/span><\/p>\n

 <\/p>\n

Vimentin tunes cell migration on collagen by controlling \u03b21 integrin activation and clustering<\/a>
\nJournal of Cell Science. 2021.<\/span>
\nOstrowska-Podhorodecka, Z., Ding, I., Lee, W., Tanic, J., Abbasi, S., Arora, P.D., Liu, R.S., Patteson, A.E., Janmey, P.A., McCulloch, C.A.<\/span><\/p>\n

 <\/p>\n

Phosphorylation of the DNA repair scaffold SLX4 drives folding of the SAP domain and activation of the MUS81-EME1 endonuclease<\/a>
\nCell Reports. 2022.<\/span>
\nPayliss, B.J., Tse. Y.W., Reichheld, S.E., Lemak, A., Yun, H.Y., Houliston, S., Patel, A., Arrowsmith, C.H., Sharpe, S., Wyatt, H.D.M.<\/span><\/p>\n

 <\/p>\n

Elevated glycolysis imparts functional ability to CD8+<\/sup> T cells in HIV infection<\/a>
\nLife Science Alliance. 2021.<\/span>
\nRahman, A.N., Liu, J., Mujib, S., Kidane, S., Ali, A., Szep, S., Han. S., Bonner, P., Parsons, M., Benko, E., Kovacs, C., Yue, F.Y., Ostrowski, M.<\/span><\/p>\n

 <\/p>\n

Polyproline type II helical antifreeze proteins are widespread in Collembola and likely originated over 400 million years ago in the Ordovician Period<\/a>
\nScientific Reports. 2023.<\/span>
\nScholl, C.L., Holmstrup, M., Graham, L.A., Davies, P.L.<\/span><\/p>\n

 <\/p>\n

In Silico Analysis of Bioactive Peptides Produced from Underutilized Sea Cucumber By-Products\u2014A Bioinformatics Approach<\/a>
\nMarine Drugs. 2022.<\/span>
\nSenadheera, T.R.L., Hossain, A., Dave, D., Shahidi, F.<\/span><\/p>\n

 <\/p>\n

Functional and physiochemical properties of protein isolates from different body parts of North Atlantic sea cucumber (Cucumaria frondosa<\/i>)<\/a>
\nScientific Reports. 2023.<\/span>
\nSenadheera, T.R.L., Hossain, A., Dave, D., Shahidi, F.<\/span><\/p>\n

 <\/p>\n

Chilling injury in human kidney tubule cells after subzero storage is not mitigated by antifreeze protein addition<\/a>
\nCryobiology. 2023.<\/span>
\nTomalty, H.E., Graham, L.A., Walker, V.K., Davies, P.L.<\/span><\/p>\n

 <\/p>\n

A Peptidisc-Based Survey of the Plasma Membrane Proteome of a Mammalian Cell<\/a>
\nMolecular & Cellular Proteomics. 2023.<\/span>
\nZhao, Z., Khurana, A., Antony, F., Young, J.W., Hewton, K.G., Brough, Z., Zhong, Parker, S.J., Duong van Hoa, F.<\/span>[\/vc_column_text][\/vc_column][\/vc_row]<\/p>\n

 <\/p>\n<\/div>","protected":false},"excerpt":{"rendered":"

[vc_row][vc_column][vc_column_text] SPARC Selected Co-authored Publications Proteomic Characterization of a Candidate Polygenic Driver of Metabolism in Non-small Cell Lung Cancer Journal of Molecular Biology. 2022. Badr, H., Blutrich, R., Chan, K., Tong, J., Taylor, P., Zhang, W., Kafri, R., R\u00f6st H.L., Tsao, M., Moran, M.F.   Integrative analysis of non-small cell lung cancer patient-derived xenografts identifies…<\/p>\n","protected":false},"author":1,"featured_media":0,"parent":0,"menu_order":1,"comment_status":"closed","ping_status":"closed","template":"","meta":{"footnotes":""},"class_list":["post-163","page","type-page","status-publish","hentry","description-off"],"yoast_head":"\nPublications - SPARC BioCentre Molecular Analysis<\/title>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/lab.research.sickkids.ca\/sparc-molecular-analysis\/publications\/\" \/>\n<meta property=\"og:locale\" content=\"en_US\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"Publications\" \/>\n<meta property=\"og:description\" content=\"[vc_row][vc_column][vc_column_text] SPARC Selected Co-authored Publications Proteomic Characterization of a Candidate Polygenic Driver of Metabolism in Non-small Cell Lung Cancer Journal of Molecular Biology. 2022. 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