{"id":10,"date":"2020-05-19T17:51:21","date_gmt":"2020-05-19T17:51:21","guid":{"rendered":"https:\/\/lab.research.sickkids.ca\/scott\/?page_id=10"},"modified":"2025-10-15T18:06:52","modified_gmt":"2025-10-15T18:06:52","slug":"publications","status":"publish","type":"page","link":"https:\/\/lab.research.sickkids.ca\/scott\/publications\/","title":{"rendered":"Publications"},"content":{"rendered":"<div class=\"wpb-content-wrapper\"><p>[vc_row][vc_column width=&#8221;1\/4&#8243; offset=&#8221;vc_hidden-sm vc_hidden-xs&#8221;][vc_single_image image=&#8221;16&#8243; img_size=&#8221;&#8221; alignment=&#8221;center&#8221; css_animation=&#8221;fadeIn&#8221; image_hovers=&#8221;false&#8221;][vc_empty_space][\/vc_column][vc_column width=&#8221;3\/4&#8243;][vc_column_text]<\/p>\n<h2>Selected publications<\/h2>\n<p>[\/vc_column_text][vc_empty_space height=&#8221;20px&#8221;]<style type=\"text\/css\" data-type=\"the7_shortcodes-inline-css\">#default-btn-25f12b69c8a2fcf40f3c82002395358a.ico-right-side > i {\n  margin-right: 0px;\n  margin-left: 8px;\n}\n#default-btn-25f12b69c8a2fcf40f3c82002395358a > i {\n  margin-right: 8px;\n}<\/style><a href=\"https:\/\/www.ncbi.nlm.nih.gov\/myncbi\/16mGNWaA48q52\/bibliography\/public\/\" class=\"default-btn-shortcode dt-btn dt-btn-l fadeInUp animate-element animation-builder link-hover-off btn-inline-left \" target=\"_blank\" id=\"default-btn-25f12b69c8a2fcf40f3c82002395358a\" title=\"Dr. Ian Scott's bibliography\" rel=\"noopener\"><span>COMPLETE BIBLIOGRAPHY<\/span><\/a>[vc_empty_space][vc_column_text css_animation=&#8221;fadeIn&#8221;]Masud, SN; Srivastava, A; Mero, P; Saba Echezarreta, V; et al. (2025) <a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/40903572\/\"><strong>Genetic suppression features ABHD18 as a Barth syndrome therapeutic target.<\/strong><\/a> <em>Nature<\/em>, doi: 10.1038\/s41586-025-09373-5.<\/p>\n<p>Erkut, E, Somerville, C, et al. (2025) <strong><a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/41033306\/\">A novel cardiovascular, craniofacial, and neurodevelopmental disorder caused by pathogenic variants in the eIF3 complex component genes EIF3A and EIF3B.<\/a><\/strong> <em>American Journal of Human Genetics<\/em>, doi: 10.1016\/j.ajhg.2025.09.008. (co-corresponding author)<\/p>\n<p>Song, M., Yuan, X., Racioppi, C., Leslie, M., Aleksandrova, A., Christiaen, L., Wilson, M.D. and Scott, I.C. (2022) <strong><a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/35275720\/\">GATA4\/5\/6 family transcription factors are conserved determinants of cardiac versus pharyngeal mesoderm fate.<\/a><\/strong> <em>Science Advances\u00a0<\/em>8 (10) doi: 10.1126\/sciadv.abg0834.<\/p>\n<p>Rosenthal, S.M., Misra, T., Abdouni, H., Branon, T.C., Ting, A.Y., Scott, I.C. and Gingras, A.C.G. (2021) <strong><a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/34332124\/\">A toolbox for efficient proximity-dependent biotinylation in early zebrafish embryos.<\/a><\/strong> <em>Molecular and Cellular Proteomics<\/em>\u00a0doi: 10.1016\/j.mcpro.2021.100128.<\/p>\n<p>Stutt, N., Song, M., Wilson, M.D. and Scott, I.C. (2021) <a href=\"https:\/\/doi.org\/10.1016\/j.semcdb.2021.11.011\"><strong>Cardiac specification during gastrulation &#8211; The Yellow Brick Road leading to Tinman.<\/strong><\/a> <em>Seminars in Cell and Developmental Biology<\/em>, doi: 10.1016\/j.semcdb.2021.11.011.<\/p>\n<p>Yuan, X., Scott, I.C. and Wilson, M.D. (2021) <a href=\"https:\/\/doi.org\/10.3389\/fgene.2021.642975\"><strong>Heart enhancers: development and disease control at a distance.<\/strong><\/a> <em>Frontiers in Genetics<\/em> 12, doi: 10.3389\/fgene.2021.642975.<\/p>\n<p>van Eif, V., Protze, S., Bosada-Musselwhite, F., Yuan, X., Sinha, T., van Duijvenboden, K., Ernault, A., Mohan, R.A., Wakker, V., de Gier-de Vries, C., Hooijkaas, I., Wilson, M.D., Bakkers, J., Boukens, B.J., Black. B., Scott, I.C. and Christoffels, V. (2020)\u00a0<strong><a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/33040635\/\">Genome-Wide Analysis Identifies an Essential Human TBX3 Pacemaker Enhancer.<\/a><\/strong> <em>Circulation Research <\/em>127(12):1522-1535.<\/p>\n<p>Liang, M., Soomro, A., Tasneem, S., Abatti, L., Alizada, A., Yuan, X., Uusk\u00fcla-Reimand, L., Antounians, L., Paterson, A., Rivard, G.-E., Scott, I.C., Mitchell, J., Hayward, C. and Wilson, M.D. (2020) <strong><a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/32663239\/\">Enhancer-gene rewiring in the pathogenesis of Quebec Platelet Disorder.<\/a><\/strong> <em>Blood<\/em> 136 (23), 2679-90.<\/p>\n<p><span data-contrast=\"auto\">Lee, S.-H., <\/span><span data-contrast=\"auto\">Hadipour-Lakmehsari<\/span><span data-contrast=\"auto\">, S., Murthy, H.R., Gibb, N., Miyake, T., Teng, A.C.T., <\/span><span data-contrast=\"auto\">Cosme<\/span><span data-contrast=\"auto\">, J., Yu, J.C., Moon, M., Lim, S.H., Wong, V., Liu, P., <\/span><span data-contrast=\"auto\">Billia<\/span><span data-contrast=\"auto\">, F., Fernandez-Gonzalez, R., <\/span><span data-contrast=\"auto\">Stagljar<\/span><span data-contrast=\"auto\">, I., Sharma, P., <\/span><span data-contrast=\"auto\">Kislinger<\/span><span data-contrast=\"auto\">, T., Scott, I.C. and <\/span><span data-contrast=\"auto\">Gramolini<\/span><span data-contrast=\"auto\">, A.O.\u00a0(2020) <strong><a href=\"https:\/\/www.ncbi.nlm.nih.gov\/pmc\/articles\/PMC7031342\/\" target=\"_blank\" rel=\"noopener noreferrer\">REEP5 depletion causes sarco-endoplasmic reticulum vacuolization and cardiac functional defects.<\/a> <\/strong><\/span><em>Nature Communications<\/em><span data-contrast=\"auto\"> 11 (1), 965.<div class=\"gap\" style=\"line-height: 15px; height: 15px;\"><\/div><\/span><\/p>\n<p><span data-contrast=\"auto\">Gibb, N., <\/span><span data-contrast=\"auto\">Lazic<\/span><span data-contrast=\"auto\">, S., Yuan, X., <\/span><span data-contrast=\"auto\">Deshwar<\/span><span data-contrast=\"auto\">, A.S., Leslie, M., Wilson, M.D. and Scott, I.C. (2018) <strong><a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/30355727\/\" target=\"_blank\" rel=\"noopener noreferrer\">Hey2 regulates the size of the cardiac progenitor pool during development.<\/a> <\/strong><\/span><em>Development<\/em><span data-contrast=\"auto\"> 145 (22), dev167510.<\/span><span data-ccp-props=\"{}\">\u00a0<\/span><\/p>\n<p style=\"padding-left: 40px\"><q class=\"text-big shortcode-pullquote wf-cell align-right wf-1\"><p><em><span class=\"TextRun SCXW76207627 BCX4\" lang=\"EN-CA\" xml:lang=\"EN-CA\" data-contrast=\"auto\"><span class=\"NormalTextRun SCXW76207627 BCX4\">Finding that <\/span><\/span><span class=\"TextRun SCXW76207627 BCX4\" lang=\"EN-CA\" xml:lang=\"EN-CA\" data-contrast=\"auto\"><span class=\"NormalTextRun SCXW76207627 BCX4\">hey2 <\/span><\/span><span class=\"TextRun SCXW76207627 BCX4\" lang=\"EN-CA\" xml:lang=\"EN-CA\" data-contrast=\"auto\"><span class=\"NormalTextRun SCXW76207627 BCX4\">restricts the contribution of Second Heart Field (SHF) cells to the developing heart, and therefore is a regulator of cardiac chamber size and cardiac proliferation.<\/span><\/span><span class=\"EOP SCXW76207627 BCX4\" data-ccp-props=\"{}\">\u00a0<\/span><\/em><span class=\"EOP SCXW227941252 BCX4\" data-ccp-props=\"{}\">\u00a0<\/span><\/p>\n<\/q><span data-contrast=\"auto\"><div class=\"gap\" style=\"line-height: 15px; height: 15px;\"><\/div><\/span><\/p>\n<p><span data-contrast=\"auto\">Yuan, X., Song, M., Devine, P., Bruneau, B.G., Scott, I.C.* and Wilson M.D.*\u00a0(2018) <a href=\"https:\/\/www.ncbi.nlm.nih.gov\/pmc\/articles\/PMC6255839\/\" target=\"_blank\" rel=\"noopener noreferrer\"><strong>Heart enhancers with deeply conserved regulatory activity are established early in zebrafish development.<\/strong><\/a> <\/span><em>Nature Communications<\/em><span data-contrast=\"auto\"> 9 (1), 4977. (* co-corresponding author)<\/span><span data-ccp-props=\"{}\">\u00a0<\/span><\/p>\n<p><i><span data-contrast=\"auto\">Chosen by Faculty of 1,000; featured as an Editor\u2019s Highlight by Nature Communications.<\/span><\/i><span data-ccp-props=\"{}\">\u00a0<\/span><\/p>\n<p style=\"padding-left: 40px\"><q class=\"text-big shortcode-pullquote wf-cell align-right wf-1\"><p><em><span class=\"TextRun SCXW227941252 BCX4\" lang=\"EN-CA\" xml:lang=\"EN-CA\" data-contrast=\"auto\"><span class=\"NormalTextRun SCXW227941252 BCX4\">Identification of conserved enhancers (<\/span><\/span><span class=\"TextRun SCXW227941252 BCX4\" lang=\"EN-CA\" xml:lang=\"EN-CA\" data-contrast=\"auto\"><span class=\"SpellingError SCXW227941252 BCX4\">aCNEs<\/span><\/span><span class=\"TextRun SCXW227941252 BCX4\" lang=\"EN-CA\" xml:lang=\"EN-CA\" data-contrast=\"auto\"><span class=\"NormalTextRun SCXW227941252 BCX4\"> \u2013 accessible conserved non-coding elements) that are active during early development and are conserved between zebrafish and human. This toolbox of 6,000+ enhancers is being exploited to identify key non-coding regulators of development, regeneration, and human disease.<\/span><\/span><span class=\"EOP SCXW227941252 BCX4\" data-ccp-props=\"{}\">\u00a0<\/span><\/em><\/p>\n<\/q><span data-contrast=\"auto\"><div class=\"gap\" style=\"line-height: 15px; height: 15px;\"><\/div><\/span><\/p>\n<p><span data-contrast=\"auto\">Deshwar<\/span><span data-contrast=\"auto\">, A.R., <\/span><span data-contrast=\"auto\">Onderisin<\/span><span data-contrast=\"auto\">, J.C., <\/span><span data-contrast=\"auto\">Aleksandrova<\/span><span data-contrast=\"auto\">, A., Yuan, X., Burrows, J.T. and Scott, I.C. (2016)\u00a0<\/span><a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/27554166\/\" target=\"_blank\" rel=\"noopener noreferrer\"><strong>Mespaa can potently induce cardiac fates in zebrafish.<\/strong><\/a> <em>Developmental Biology<\/em> <span data-contrast=\"auto\">418 (1), 17-27.<\/span><span data-ccp-props=\"{}\"> <div class=\"gap\" style=\"line-height: 15px; height: 15px;\"><\/div><\/span><\/p>\n<p><span data-contrast=\"auto\">Deshwar<\/span><span data-contrast=\"auto\">, A.R., <\/span><span data-contrast=\"auto\">Chng<\/span><span data-contrast=\"auto\">, S.C., Ho, L., <\/span><span data-contrast=\"auto\">Reversade<\/span><span data-contrast=\"auto\">, B. and Scott, I.C. (2016)\u00a0<\/span><a href=\"https:\/\/www.ncbi.nlm.nih.gov\/pmc\/articles\/PMC4859801\/\" target=\"_blank\" rel=\"noopener noreferrer\"><strong>The Apelin receptor enhances Nodal\/TGF\u03b2\u00a0signaling to ensure proper cardiac development.<\/strong><\/a> <em>eLife<\/em> <span data-contrast=\"auto\">10:e<\/span><span data-contrast=\"auto\">13758.<\/span><span data-ccp-props=\"{}\"> <div class=\"gap\" style=\"line-height: 15px; height: 15px;\"><\/div><\/span><\/p>\n<p><span data-contrast=\"auto\">Lou, X., Burrows, J. and Scott, I.C. (2015)\u00a0<\/span><a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/26553192\/\" target=\"_blank\" rel=\"noopener noreferrer\"><strong>Med14 cooperates with brg1 in the differentiation of skeletogenic neural crest.<\/strong><\/a> <em>BMC Developmental Biology<\/em><span data-contrast=\"auto\"> 15(1):41.<\/span><span data-ccp-props=\"{}\"> <div class=\"gap\" style=\"line-height: 15px; height: 15px;\"><\/div><\/span><\/p>\n<p><span data-contrast=\"auto\">Burrows, J.T.A., Pearson, B.J. and Scott, I.C. (2015)\u00a0<\/span><a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/25772472\/\" target=\"_blank\" rel=\"noopener noreferrer\"><strong>An in vivo requirement for the Mediator subunit Med14 in the maintenance of stem cell populations.<\/strong><\/a> <em>Stem Cell Reports<\/em><span data-contrast=\"auto\"> S2213-6711.<\/span><span data-ccp-props=\"{}\"> <div class=\"gap\" style=\"line-height: 15px; height: 15px;\"><\/div><\/span><\/p>\n<p><span data-contrast=\"auto\">Yoruk<\/span><span data-contrast=\"auto\">, B., <\/span><span data-contrast=\"auto\">Giller<\/span><span data-contrast=\"auto\">, B.S., Chi, N.C. and Scott, I.C. (2012)\u00a0<\/span><a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/22182521\/\" target=\"_blank\" rel=\"noopener noreferrer\"><strong>Ccm3 functions in a manner distinct from Ccm1 and Ccm2 in a zebrafish model of CCM vascular disease.<\/strong><\/a> <em>Developmental Biology<\/em><span data-contrast=\"auto\"> 362 (2), 121-131.<\/span><span data-ccp-props=\"{}\">\u00a0<\/span><\/p>\n<p style=\"padding-left: 40px\"><q class=\"text-big shortcode-pullquote wf-cell align-right wf-1\"><p><em><span class=\"TextRun SCXW188159369 BCX4\" lang=\"EN-CA\" xml:lang=\"EN-CA\" data-contrast=\"auto\"><span class=\"NormalTextRun SCXW188159369 BCX4\">Analysis of <\/span><\/span><span class=\"TextRun SCXW188159369 BCX4\" lang=\"EN-CA\" xml:lang=\"EN-CA\" data-contrast=\"auto\"><span class=\"NormalTextRun SCXW188159369 BCX4\">ccm3 <\/span><\/span><span class=\"TextRun SCXW188159369 BCX4\" lang=\"EN-CA\" xml:lang=\"EN-CA\" data-contrast=\"auto\"><span class=\"NormalTextRun SCXW188159369 BCX4\">loss-of-function in zebrafish, and demonstration that CCM3 may function is a pathway distinct from CCM1\/2.<\/span><\/span><\/em><span class=\"EOP SCXW188159369 BCX4\" data-ccp-props=\"{}\">\u00a0<\/span><\/p>\n<\/q><span data-contrast=\"auto\"><div class=\"gap\" style=\"line-height: 15px; height: 15px;\"><\/div><\/span><\/p>\n<p><span data-contrast=\"auto\">Paskaradevan<\/span><span data-contrast=\"auto\">, S. and Scott, I.C. (2012) <\/span><a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/23213418\/\" target=\"_blank\" rel=\"noopener noreferrer\"><strong>The Aplnr GPCR signals independently of G\u03b1i\/o proteins and cell-non-autonomously in the development of myocardial progenitor cells.<\/strong><\/a> <em>Biology OPEN<\/em> 1 (3), 275-85.<span data-contrast=\"auto\"><div class=\"gap\" style=\"line-height: 15px; height: 15px;\"><\/div><\/span><span data-ccp-props=\"{}\">\u00a0<\/span><br \/>\n<span data-contrast=\"auto\">Lou, X., <\/span><span data-contrast=\"auto\">Deshwar<\/span><span data-contrast=\"auto\">, A.R., Crump, J.G. and Scott, I.C. (2011)\u00a0<\/span><a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/21715426\/\" target=\"_blank\" rel=\"noopener noreferrer\"><strong>Smarcd3b and Gata5 promote a cardiac progenitor fate in the zebrafish embryo.<\/strong><\/a> <em>Development<\/em> 138 (15), 3113-23.<\/p>\n<p style=\"padding-left: 40px\"><q class=\"text-big shortcode-pullquote wf-cell align-right wf-1\"><p><em><span class=\"TextRun SCXW219814859 BCX4\" lang=\"EN-CA\" xml:lang=\"EN-CA\" data-contrast=\"auto\"><span class=\"NormalTextRun SCXW219814859 BCX4\">Demonstration that activity of Gata5 alone can drive cells to migrate and contribute to heart development. This again suggests that key events in <\/span><\/span><span class=\"TextRun SCXW219814859 BCX4\" lang=\"EN-CA\" xml:lang=\"EN-CA\" data-contrast=\"auto\"><span class=\"SpellingError SCXW219814859 BCX4\">cardiogenesis<\/span><\/span><span class=\"TextRun SCXW219814859 BCX4\" lang=\"EN-CA\" xml:lang=\"EN-CA\" data-contrast=\"auto\"><span class=\"NormalTextRun SCXW219814859 BCX4\"> happen very early in development, well before the expression of canonical cardiac mesoderm markers.<\/span><\/span><span class=\"EOP SCXW219814859 BCX4\" data-ccp-props=\"{}\">\u00a0<\/span><\/em><\/p>\n<\/q><span data-contrast=\"auto\"><div class=\"gap\" style=\"line-height: 15px; height: 15px;\"><\/div><\/span><\/p>\n<p>Lazic, S. and Scott, I.C. (2011)\u00a0<a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/21466801\/\" target=\"_blank\" rel=\"noopener noreferrer\"><strong>Mef2cb regulates late myocardial cell addition from a second heart field-like population of progenitors in zebrafish.<\/strong><\/a> <em>Developmental Biology<\/em> 354 (1), 123-133.<\/p>\n<p style=\"padding-left: 40px\"><q class=\"text-big shortcode-pullquote wf-cell align-right wf-1\"><p><em><span class=\"TextRun SCXW90276786 BCX4\" lang=\"EN-CA\" xml:lang=\"EN-CA\" data-contrast=\"auto\"><span class=\"NormalTextRun SCXW90276786 BCX4\">Demonstration that the zebrafish heart, as is true for the mammalian heart, is built via two waves of cell addition.<\/span><\/span><span class=\"EOP SCXW90276786 BCX4\" data-ccp-props=\"{}\">\u00a0<\/span><\/em><\/p>\n<\/q><span data-contrast=\"auto\"><div class=\"gap\" style=\"line-height: 15px; height: 15px;\"><\/div><\/span><\/p>\n<p>Takeuchi, J.K.*, Lou, X.*, Alexander, J.M., Sugizaki, H., Delgado-Olguin, P., Holloway, A.K., Mori, A.D., Wylie, J.N., Munson, C., Zhu, Y., Zhou, Y.-Q., Yeh, R.-F., Henkelman, R.M., Harvey, R.P., Metzger, D., Chambon, P., Stainier, D.Y., Pollard, K.S., Scott, I.C. and Bruneau, B.G. (2011)\u00a0<a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/21304516\/\" target=\"_blank\" rel=\"noopener noreferrer\"><strong>Chromatin remodelling complex dosage modulates transcription factor function in heart development.<\/strong><\/a> <em>Nature Communications<\/em> 2, 187.<span data-contrast=\"auto\"><div class=\"gap\" style=\"line-height: 15px; height: 15px;\"><\/div><\/span><\/p>\n<p>Scott, I.C., Masri, B., D\u2019Amico, L.A., Jin, S.-W., Jungblut, B., Wehman, A.M., Baier, H., Audigier, Y. and Stainier, D.Y.R. (2007)\u00a0<a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/17336906\/\" target=\"_blank\" rel=\"noopener noreferrer\"><strong>The G protein-coupled receptor Agtrl1b regulates early development of myocardial progenitors.<\/strong><\/a> <em>Developmental Cell<\/em> 12 (3), 403-413.<\/p>\n<p style=\"padding-left: 40px\"><q class=\"text-big shortcode-pullquote wf-cell align-right wf-1\"><p><em><span class=\"TextRun SCXW266038892 BCX4\" lang=\"EN-CA\" xml:lang=\"EN-CA\" data-contrast=\"auto\"><span class=\"NormalTextRun SCXW266038892 BCX4\">First description of the role of <\/span><\/span><span class=\"TextRun SCXW266038892 BCX4\" lang=\"EN-CA\" xml:lang=\"EN-CA\" data-contrast=\"auto\"><span class=\"SpellingError SCXW266038892 BCX4\">Aplnr<\/span><\/span><span class=\"TextRun SCXW266038892 BCX4\" lang=\"EN-CA\" xml:lang=\"EN-CA\" data-contrast=\"auto\"><span class=\"NormalTextRun SCXW266038892 BCX4\"> signaling in cardiac development<\/span><\/span><span class=\"TextRun SCXW266038892 BCX4\" lang=\"EN-CA\" xml:lang=\"EN-CA\" data-contrast=\"auto\"><span class=\"NormalTextRun SCXW266038892 BCX4\">, and suggestion that early events during gastrulation may primes cells for cardiac contribution.<\/span><\/span><span class=\"EOP SCXW266038892 BCX4\" data-ccp-props=\"{}\">\u00a0<\/span><\/em><\/p>\n<\/q><span data-contrast=\"auto\"><div class=\"gap\" style=\"line-height: 15px; height: 15px;\"><\/div><\/span><\/p>\n<p>[\/vc_column_text][\/vc_column][\/vc_row][vc_row][vc_column][vc_column_text][\/vc_column_text][\/vc_column][\/vc_row]<\/p>\n<\/div>","protected":false},"excerpt":{"rendered":"<p>[vc_row][vc_column width=&#8221;1\/4&#8243; offset=&#8221;vc_hidden-sm vc_hidden-xs&#8221;][vc_single_image image=&#8221;16&#8243; img_size=&#8221;&#8221; alignment=&#8221;center&#8221; css_animation=&#8221;fadeIn&#8221; image_hovers=&#8221;false&#8221;][vc_empty_space][\/vc_column][vc_column width=&#8221;3\/4&#8243;][vc_column_text] Selected publications [\/vc_column_text][vc_empty_space height=&#8221;20px&#8221;][vc_empty_space][vc_column_text css_animation=&#8221;fadeIn&#8221;]Masud, SN; Srivastava, A; Mero, P; Saba Echezarreta, V; et al. (2025) Genetic suppression features ABHD18 as a Barth syndrome therapeutic target. Nature, doi: 10.1038\/s41586-025-09373-5. Erkut, E, Somerville, C, et al. (2025) A novel cardiovascular, craniofacial, and neurodevelopmental disorder caused by&hellip;<\/p>\n","protected":false},"author":2,"featured_media":0,"parent":0,"menu_order":0,"comment_status":"closed","ping_status":"closed","template":"","meta":{"footnotes":""},"class_list":["post-10","page","type-page","status-publish","hentry","description-off"],"yoast_head":"<!-- This site is optimized with the Yoast SEO Premium plugin v27.0 (Yoast SEO v27.0) - https:\/\/yoast.com\/product\/yoast-seo-premium-wordpress\/ -->\n<title>Publications - Ian Scott Lab<\/title>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/lab.research.sickkids.ca\/scott\/publications\/\" \/>\n<meta property=\"og:locale\" content=\"en_US\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"Publications\" \/>\n<meta property=\"og:description\" content=\"[vc_row][vc_column width=&#8221;1\/4&#8243; offset=&#8221;vc_hidden-sm vc_hidden-xs&#8221;][vc_single_image image=&#8221;16&#8243; img_size=&#8221;&#8221; alignment=&#8221;center&#8221; css_animation=&#8221;fadeIn&#8221; image_hovers=&#8221;false&#8221;][vc_empty_space][\/vc_column][vc_column width=&#8221;3\/4&#8243;][vc_column_text] Selected publications [\/vc_column_text][vc_empty_space height=&#8221;20px&#8221;][vc_empty_space][vc_column_text css_animation=&#8221;fadeIn&#8221;]Masud, SN; Srivastava, A; Mero, P; Saba Echezarreta, V; et al. (2025) Genetic suppression features ABHD18 as a Barth syndrome therapeutic target. Nature, doi: 10.1038\/s41586-025-09373-5. Erkut, E, Somerville, C, et al. 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(2025) Genetic suppression features ABHD18 as a Barth syndrome therapeutic target. Nature, doi: 10.1038\/s41586-025-09373-5. Erkut, E, Somerville, C, et al. 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