{"id":9,"date":"2016-11-01T15:39:26","date_gmt":"2016-11-01T15:39:26","guid":{"rendered":"https:\/\/avadawebsites.wpengine.com\/science\/?page_id=9"},"modified":"2025-01-30T20:27:37","modified_gmt":"2025-01-30T20:27:37","slug":"research","status":"publish","type":"page","link":"https:\/\/lab.research.sickkids.ca\/ratjen\/research\/","title":{"rendered":"Research"},"content":{"rendered":"

Our Research<\/h1><\/div>
<\/div><\/div><\/div><\/div>

We aim to provide insight into patterns of disease progression, risk factors for specific outcomes and real-life effectiveness of new treatments through several interventional and observational studies. As part of the <\/span><\/span>Cystic Fibrosis (CF) Centre<\/a><\/span> at SickKids, a collaborative effort on the application of new therapies and technologies are explored to provide meaningful impacts in CF patient care and education.<\/span><\/span><\/p>\n<\/div><\/div><\/div>

\"Photo<\/span><\/div><\/div><\/div><\/div><\/div><\/div>
<\/div>
<\/div><\/div>
<\/div><\/div><\/div><\/div><\/div><\/div><\/div>

What We Do<\/h2>\n<\/div>
<\/div><\/div><\/div><\/div><\/div><\/div>
\"Photo<\/span><\/div><\/div><\/div>

1.<\/span> <\/b><\/span><\/p>\n

Novel Physiological Outcomes: <\/b>
\nOur research focuses on physiological outcomes that can better identify early lung disease and monitor patients with respiratory diseases. Currently, many of our studies focus on the Multiple Breath Washout test which measures how effectively the lungs clears a tracer gas. Our research studies aim to understand how we can interpret the results of this test to monitor patients with CF.<\/span><\/p>\n

2.<\/span> <\/b><\/span><\/p>\n

Translational Research: <\/b>
\nWith a strong emphasis on evidence-based research, our team conducts interventional and observational studies in children with CF to improve the quality and longevity of life. The research studies offer insight into patterns of disease progression, risk factors for specific outcomes and real-life effectiveness of new treatments.<\/span><\/p>\n

3.<\/span> <\/b><\/span><\/p>\n

Multiple Breath Washout: <\/b>
\nThe Multiple Breath Washout (MBW) test has been identified as promising outcome for evaluating the efficacy of new treatments. We are linked with centres in Canad<\/span>a, the US, Europe and Australia and work together closely to advance CF care.<\/span><\/p>\n<\/div><\/div><\/div><\/div><\/div><\/p>\n","protected":false},"excerpt":{"rendered":"","protected":false},"author":1,"featured_media":0,"parent":0,"menu_order":0,"comment_status":"closed","ping_status":"closed","template":"100-width.php","meta":{"footnotes":""},"class_list":["post-9","page","type-page","status-publish","hentry"],"yoast_head":"\nResearch - Ratjen Lab<\/title>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/lab.research.sickkids.ca\/ratjen\/research\/\" \/>\n<meta property=\"og:locale\" content=\"en_US\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"Research\" \/>\n<meta property=\"og:url\" content=\"https:\/\/lab.research.sickkids.ca\/ratjen\/research\/\" \/>\n<meta property=\"og:site_name\" content=\"Ratjen Lab\" \/>\n<meta property=\"article:modified_time\" content=\"2025-01-30T20:27:37+00:00\" \/>\n<meta name=\"twitter:card\" content=\"summary_large_image\" \/>\n<meta name=\"twitter:label1\" content=\"Est. reading time\" \/>\n\t<meta name=\"twitter:data1\" content=\"12 minutes\" \/>\n<script type=\"application\/ld+json\" class=\"yoast-schema-graph\">{\"@context\":\"https:\/\/schema.org\",\"@graph\":[{\"@type\":\"WebPage\",\"@id\":\"https:\/\/lab.research.sickkids.ca\/ratjen\/research\/\",\"url\":\"https:\/\/lab.research.sickkids.ca\/ratjen\/research\/\",\"name\":\"Research - Ratjen Lab\",\"isPartOf\":{\"@id\":\"https:\/\/lab.research.sickkids.ca\/ratjen\/#website\"},\"datePublished\":\"2016-11-01T15:39:26+00:00\",\"dateModified\":\"2025-01-30T20:27:37+00:00\",\"breadcrumb\":{\"@id\":\"https:\/\/lab.research.sickkids.ca\/ratjen\/research\/#breadcrumb\"},\"inLanguage\":\"en-US\",\"potentialAction\":[{\"@type\":\"ReadAction\",\"target\":[\"https:\/\/lab.research.sickkids.ca\/ratjen\/research\/\"]}]},{\"@type\":\"BreadcrumbList\",\"@id\":\"https:\/\/lab.research.sickkids.ca\/ratjen\/research\/#breadcrumb\",\"itemListElement\":[{\"@type\":\"ListItem\",\"position\":1,\"name\":\"Home\",\"item\":\"https:\/\/lab.research.sickkids.ca\/ratjen\/\"},{\"@type\":\"ListItem\",\"position\":2,\"name\":\"Research\"}]},{\"@type\":\"WebSite\",\"@id\":\"https:\/\/lab.research.sickkids.ca\/ratjen\/#website\",\"url\":\"https:\/\/lab.research.sickkids.ca\/ratjen\/\",\"name\":\"Ratjen Lab\",\"description\":\"Studying new therapies to improve patients\u2019 outcomes\",\"potentialAction\":[{\"@type\":\"SearchAction\",\"target\":{\"@type\":\"EntryPoint\",\"urlTemplate\":\"https:\/\/lab.research.sickkids.ca\/ratjen\/?s={search_term_string}\"},\"query-input\":{\"@type\":\"PropertyValueSpecification\",\"valueRequired\":true,\"valueName\":\"search_term_string\"}}],\"inLanguage\":\"en-US\"}]}<\/script>\n<!-- \/ Yoast SEO Premium plugin. -->","yoast_head_json":{"title":"Research - Ratjen Lab","robots":{"index":"index","follow":"follow","max-snippet":"max-snippet:-1","max-image-preview":"max-image-preview:large","max-video-preview":"max-video-preview:-1"},"canonical":"https:\/\/lab.research.sickkids.ca\/ratjen\/research\/","og_locale":"en_US","og_type":"article","og_title":"Research","og_url":"https:\/\/lab.research.sickkids.ca\/ratjen\/research\/","og_site_name":"Ratjen Lab","article_modified_time":"2025-01-30T20:27:37+00:00","twitter_card":"summary_large_image","twitter_misc":{"Est. reading time":"12 minutes"},"schema":{"@context":"https:\/\/schema.org","@graph":[{"@type":"WebPage","@id":"https:\/\/lab.research.sickkids.ca\/ratjen\/research\/","url":"https:\/\/lab.research.sickkids.ca\/ratjen\/research\/","name":"Research - Ratjen Lab","isPartOf":{"@id":"https:\/\/lab.research.sickkids.ca\/ratjen\/#website"},"datePublished":"2016-11-01T15:39:26+00:00","dateModified":"2025-01-30T20:27:37+00:00","breadcrumb":{"@id":"https:\/\/lab.research.sickkids.ca\/ratjen\/research\/#breadcrumb"},"inLanguage":"en-US","potentialAction":[{"@type":"ReadAction","target":["https:\/\/lab.research.sickkids.ca\/ratjen\/research\/"]}]},{"@type":"BreadcrumbList","@id":"https:\/\/lab.research.sickkids.ca\/ratjen\/research\/#breadcrumb","itemListElement":[{"@type":"ListItem","position":1,"name":"Home","item":"https:\/\/lab.research.sickkids.ca\/ratjen\/"},{"@type":"ListItem","position":2,"name":"Research"}]},{"@type":"WebSite","@id":"https:\/\/lab.research.sickkids.ca\/ratjen\/#website","url":"https:\/\/lab.research.sickkids.ca\/ratjen\/","name":"Ratjen Lab","description":"Studying new therapies to improve patients\u2019 outcomes","potentialAction":[{"@type":"SearchAction","target":{"@type":"EntryPoint","urlTemplate":"https:\/\/lab.research.sickkids.ca\/ratjen\/?s={search_term_string}"},"query-input":{"@type":"PropertyValueSpecification","valueRequired":true,"valueName":"search_term_string"}}],"inLanguage":"en-US"}]}},"_links":{"self":[{"href":"https:\/\/lab.research.sickkids.ca\/ratjen\/wp-json\/wp\/v2\/pages\/9","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/lab.research.sickkids.ca\/ratjen\/wp-json\/wp\/v2\/pages"}],"about":[{"href":"https:\/\/lab.research.sickkids.ca\/ratjen\/wp-json\/wp\/v2\/types\/page"}],"author":[{"embeddable":true,"href":"https:\/\/lab.research.sickkids.ca\/ratjen\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/lab.research.sickkids.ca\/ratjen\/wp-json\/wp\/v2\/comments?post=9"}],"version-history":[{"count":0,"href":"https:\/\/lab.research.sickkids.ca\/ratjen\/wp-json\/wp\/v2\/pages\/9\/revisions"}],"wp:attachment":[{"href":"https:\/\/lab.research.sickkids.ca\/ratjen\/wp-json\/wp\/v2\/media?parent=9"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}