{"id":263,"date":"2017-09-22T20:05:08","date_gmt":"2017-09-22T20:05:08","guid":{"rendered":"https:\/\/lab.research.sickkids.ca\/neuroinflamm\/?page_id=263"},"modified":"2025-05-08T11:42:34","modified_gmt":"2025-05-08T15:42:34","slug":"research","status":"publish","type":"page","link":"https:\/\/lab.research.sickkids.ca\/neuroinflamm\/research\/","title":{"rendered":"Research"},"content":{"rendered":"<div class=\"wpb-content-wrapper\"><p>[vc_row][vc_column][vc_empty_space height=&#8221;60px&#8221;]<div id=\"uvc-type-wrap-1901\"  data-ultimate-target='#uvc-type-wrap-1901'  data-responsive-json-new='{\"font-size\":\"desktop:20px;\",\"line-height\":\"\"}'  class=\"uvc-type-wrap vc_custom_1627682174305 ult-adjust-bottom-margin ult-responsive  uvc-type-align-center uvc-type-no-prefix uvc-wrap-164073416669e4c1e11fc91\" style=\"text-align:center;\"><div id=\"vticker-164073416669e4c1e11fc91\"  data-ultimate-target=&#039;#uvc-type-wrap-1901&#039;  data-responsive-json-new=&#039;{&quot;font-size&quot;:&quot;desktop:20px;&quot;,&quot;line-height&quot;:&quot;&quot;}&#039;  class=\"ultimate-vticker ticker  ultimate-fancy-text-inherit\" style=\"color:#767a83; font-weight:normal; text-transform: unset;\"><ul><li style=&quot;opacity:1&quot;>Our Paediatric Neuroinflammatory Disorders program, in collaboration with other site investigators across Canada and internationally, are currently recruiting for several studies under the following areas:<\/li><\/ul><\/div><script type=\"text\/javascript\">\n\t\t\t\t\t\tjQuery(function($){\n\t\t\t\t\t\t\t$(document).ready(function(){\n\t\t\t\t\t\t\t\tif( typeof jQuery(\"#vticker-164073416669e4c1e11fc91\").easyTicker == \"function\"){\n\t\t\t\t\t\t\t\t\t$(\"#vticker-164073416669e4c1e11fc91\").find(\"li\").css(\"opacity\",\"1\");\n\t\t\t\t\t\t\t\t\t\n\t\t\t\t\t\t\t\t\t$(\"#vticker-164073416669e4c1e11fc91\").easyTicker({\n\t\t\t\t\t\t\t\t\t\tdirection: \"up\",\n\t\t\t\t\t\t\t\t\t\teasing: \"swing\",\n\t\t\t\t\t\t\t\t\t\tspeed: \"200\",\n\t\t\t\t\t\t\t\t\t\tinterval: \"30000\",\n\t\t\t\t\t\t\t\t\t\theight: \"auto\",\n\t\t\t\t\t\t\t\t\t\tvisible: \"1\",\n\t\t\t\t\t\t\t\t\t\tmousePause: \"1\",\n\t\t\t\t\t\t\t\t\t\tcontrols: {\n\t\t\t\t\t\t\t\t\t\t\tup: \"\",\n\t\t\t\t\t\t\t\t\t\t\tdown: \"\",\n\t\t\t\t\t\t\t\t\t\t\ttoggle: \"\",\n\t\t\t\t\t\t\t\t\t\t\tplayText: \"Play\",\n\t\t\t\t\t\t\t\t\t\t\tstopText: \"Stop\"\n\t\t\t\t\t\t\t\t\t\t}\n\t\t\t\t\t\t\t\t\t});\n\t\t\t\t\t\t\t\t}\n\t\t\t\t\t\t\t});\n\t\t\t\t\t\t});\n\t\t\t\t\t<\/script><\/div>[vc_empty_space height=&#8221;10&#8243;][\/vc_column][\/vc_row][vc_row][vc_column]<div id=\"advanced-tabs-desc-wrap-8715\" class=\"ult_tabs \" style=\" \" data-tabsstyle=\"style2\"\n data-titlebg=\"#e7ecea\" data-titlecolor=\"#74777b\" data-fullheight=\"off\"\n data-titlehoverbg=\"#4f90d1\" data-titlehovercolor=\"#ffffff\"\n data-rotatetabs=\"0\" data-responsivemode=\"Both\" data-animation=\"Slide-Zoom\"\ndata-activetitle=\"#ffffff\" data-activeicon=\"\" data-activebg=\"#4f90d1\"  data-respmode=\"Tabs\" data-respwidth=\"400\" data-scroll = \"on\" data-activeindex=\"1\"><ul id=advanced-tabs-wrap-6661 class=\"ult_tabmenu style2 \" style=\"color:transparent;border-bottom-color:transparent;border-bottom-width:0px;border-bottom-style:solid;border-bottom-width:0px;\"><li class=\"ult_tab_li   \" data-iconcolor=\"#74777b\" data-iconhover=\"#ffffff\" style=\"\">\n\t\t\t\t\t<a href=\"#1628818368354-7\" id=\"1628818368354-7\" style=\"color:#74777b;background-color:#e7ecea;border-top-left-radius:8px;;  \" class=\"ult_a \">\n\t\t\t\t\t   <span class=\"ult_tab_main  Both \">\n\t\t\t\t\t    <span class=\"ult_tab_section\">\n\t\t\t\t\t  \t\t<span  data-ultimate-target='#advanced-tabs-wrap-6661 .ult-span-text'  data-responsive-json-new='{\"font-size\":\"desktop:15px;\",\"line-height\":\"\"}'  class=\"ult-span-text ult-responsive\" style=\"\">Patient Opportunities<\/span>\n\t\t\t\t\t\t   \t<span class=\"aio-icon none ult_tab_iconright\" style=\"color:#74777b;font-size:15px;\">\n\t\t\t\t\t\t   \t<i class=\"   ult_tab_icon\"  ><\/i>\n\t\t\t\t\t\t   <\/span>\n\t\t\t\t\t\t<\/span>\n\t\t\t\t\t   <\/span>\n\n\t\t\t\t\t<\/a>\n\t\t\t\t\t<\/li><li class=\"ult_tab_li   \" data-iconcolor=\"#74777b\" data-iconhover=\"#ffffff\" style=\"\">\n\t\t\t\t\t<a href=\"#tab_hc\" id=\"tab_hc\" style=\"color:#74777b;background-color:#e7ecea;border-top-right-radius:8px;;  \" class=\"ult_a \">\n\t\t\t\t\t   <span class=\"ult_tab_main  Both \">\n\t\t\t\t\t    <span class=\"ult_tab_section\">\n\t\t\t\t\t  \t\t<span  data-ultimate-target='#advanced-tabs-wrap-6661 .ult-span-text'  data-responsive-json-new='{\"font-size\":\"desktop:15px;\",\"line-height\":\"\"}'  class=\"ult-span-text ult-responsive\" style=\"\">Healthy Control Opportunities<\/span>\n\t\t\t\t\t\t   \t<span class=\"aio-icon none ult_tab_iconright\" style=\"color:#74777b;font-size:15px;\">\n\t\t\t\t\t\t   \t<i class=\"   ult_tab_icon\"  ><\/i>\n\t\t\t\t\t\t   <\/span>\n\t\t\t\t\t\t<\/span>\n\t\t\t\t\t   <\/span>\n\n\t\t\t\t\t<\/a>\n\t\t\t\t\t<\/li><\/ul><div  data-ultimate-target='#advanced-tabs-desc-wrap-8715 .ult_tabcontent .ult_tab_min_contain  p'  data-responsive-json-new='{\"font-size\":\"\",\"line-height\":\"\"}' class=\"ult_tabcontent ult-responsive style2\" style=\"color:#74777b;\"><div class=\"ult_tab_min_contain tabanimate\" >\n\t\t\t<div  class=\"ult_tabitemname\"  >\n\t\t\t\t<div class=\"ult_exp_section_layer ult-adjust-bottom-margin  \" >\n\t\t<div id=\"uvc-exp-wrap-4619\" role=\"button\" tabindex=\"0\" aria-pressed=\"false\"  data-ultimate-target='#uvc-exp-wrap-4619'  data-responsive-json-new='{\"font-size\":\"desktop:25px;\",\"line-height\":\"desktop:50px;\"}'  class=\"ult_exp_section  ult-responsive \" style=\"color:#0068b3;background-color:#eaf2fb;font-weight:bold;  text-align:center;\" data-textcolor=\"#0068b3\"data-texthover=\"#db58a7\"data-icncolor=\"#333333\"data-ihover=\"#333333\"data-height=\"0\"data-cntbg=\"#eaf2fb\"data-cnthvrbg=\"rgba(219,88,167,0.06)\"data-headerbg=\"#eaf2fb\"data-headerhover=\"rgba(219,88,167,0.06)\"data-title=\"For Multiple Sclerosis\"data-newtitle=\"For Multiple Sclerosis\"data-icon=\"\"data-newicon=\"\"data-activeicon=\"#333333\"data-effect=\"slideToggle\"data-override=\"0\"data-activetitle=\"#db58a7\"data-activebg=\"rgba(219,88,167,0.06)\"data-img=\"\"data-newimg=\"\"><div  class=\"ult_exp_section-main \">\n\t\t\t\t\t<div class=\"ult_expheader\" >For Multiple Sclerosis\n\t\t\t\t\t <\/div><\/div>\n\t\t\t\t<\/div><div class=\"ult_exp_content \" style=\"background-color:rgba(219,88,167,0.06);  \"><div class=\"ult_ecpsub_cont\" style=\" \" >[vc_column_text css=&#8221;.vc_custom_1644419278134{margin-top: -20px !important;padding-right: 20px !important;padding-left: 20px !important;}&#8221;]<\/p>\n<p>&nbsp;<\/p>\n<p style=\"text-align: left;font-size: 18px\"><strong>Metformin in Children and Young Adults with MS Study<\/strong><\/p>\n<p style=\"text-align: left;font-size: 18px\">We want to see if we can repair damaged myelin in children and young adults with MS using a drug called metformin. Previous research has shown that metformin helps repair myelin in mice and may associate with decreased relapses in adults with MS and metabolic syndromes. <a href=\"https:\/\/lab.research.sickkids.ca\/neuroinflamm\/research\/visual-neurocognitive-outcomes\/\">Learn more here<\/a>.<\/p>\n<p style=\"text-align: left;font-size: 18px\">You may be eligible for this study if you:<\/p>\n<ul>\n<li style=\"font-size: 18px;text-align: left\">are between 10 and 26 years old;<\/li>\n<li style=\"font-size: 18px;text-align: left\">have been diagnosed with MS.<\/li>\n<\/ul>\n<p style=\"text-align: left;font-size: 18px\">If interested in learning more, please contact <a href=\"mailto:yeh.team@sickkids.ca\">Brenna Wong<\/a> (416-813-7654 x <strong>415744<\/strong>).<\/p>\n<p>&nbsp;<\/p>\n<p style=\"text-align: left;font-size: 18px\"><strong>Participation, Environment, And Key Clinical and Health Outcomes in Children with Multiple Sclerosis (PEACH)<\/strong><\/p>\n<p style=\"text-align: left;font-size: 18px\">We are currently conducting and recruiting for a new study looking at the relationship between participation in home, school and community activities, and mental health in children and youth with multiple sclerosis (MS). We hope to use this information to better understand how neuroinflammatory disease can affect a child\u2019s mental health and ability to participate in activities at home, school and in the community. Over the course of the study, we hope to also identify what other factors affect their ability to participate in these activities.<\/p>\n<p style=\"text-align: left;font-size: 18px\">You may be eligible for this study if you:<\/p>\n<ul>\n<li style=\"font-size: 18px;text-align: left\">are between 5 and 17 years old;<\/li>\n<li style=\"font-size: 18px;text-align: left\">have been diagnosed with MS.<\/li>\n<\/ul>\n<p style=\"text-align: left;font-size: 18px\">If interested in learning more, please contact <a href=\"paul.yoo@sickkids.ca\">Paul Yoo<\/a> (416-813-7654 x <strong>328190<\/strong>).<\/p>\n<p>&nbsp;<\/p>\n<p>[\/vc_column_text]<\/div><\/div>\n\n\t\t\t<\/div><div class=\"ult_exp_section_layer ult-adjust-bottom-margin  \" >\n\t\t<div id=\"uvc-exp-wrap-8649\" role=\"button\" tabindex=\"0\" aria-pressed=\"false\"  data-ultimate-target='#uvc-exp-wrap-8649'  data-responsive-json-new='{\"font-size\":\"desktop:25px;\",\"line-height\":\"desktop:50px;\"}'  class=\"ult_exp_section  ult-responsive \" style=\"color:#0068b3;background-color:#eaf2fb;font-weight:bold;  text-align:center;\" data-textcolor=\"#0068b3\"data-texthover=\"#db58a7\"data-icncolor=\"#333333\"data-ihover=\"#333333\"data-height=\"0\"data-cntbg=\"#eaf2fb\"data-cnthvrbg=\"rgba(219,88,167,0.06)\"data-headerbg=\"#eaf2fb\"data-headerhover=\"rgba(219,88,167,0.06)\"data-title=\"For OMAS\"data-newtitle=\"For OMAS\"data-icon=\"\"data-newicon=\"\"data-activeicon=\"#333333\"data-effect=\"slideToggle\"data-override=\"0\"data-activetitle=\"#db58a7\"data-activebg=\"rgba(219,88,167,0.06)\"data-img=\"\"data-newimg=\"\"><div  class=\"ult_exp_section-main \">\n\t\t\t\t\t<div class=\"ult_expheader\" >For OMAS\n\t\t\t\t\t <\/div><\/div>\n\t\t\t\t<\/div><div class=\"ult_exp_content \" style=\"background-color:rgba(219,88,167,0.06);  \"><div class=\"ult_ecpsub_cont\" style=\" \" >[vc_column_text css=&#8221;.vc_custom_1644419191225{margin-top: -20px !important;padding-right: 20px !important;padding-left: 20px !important;}&#8221;]<\/p>\n<p style=\"text-align: left;font-size: 18px\"><strong>OMAS Study<\/strong><\/p>\n<p style=\"text-align: left;font-size: 18px\">The goal of this study is to investigate eye movement outcomes in relation to brain volume, cognitive function, and disease severity in pediatric OMAS. <a href=\"https:\/\/lab.research.sickkids.ca\/neuroinflamm\/research\/visual-neurocognitive-outcomes\/\">Learn more here<\/a>.<\/p>\n<p style=\"text-align: left;font-size: 18px\">You may be eligible for this study if you:<\/p>\n<ul>\n<li style=\"font-size: 18px;text-align: left\">are between 6 and 18 years old;<\/li>\n<li style=\"font-size: 18px;text-align: left\">have been diagnosed with OMAS.<\/li>\n<\/ul>\n<p style=\"text-align: left;font-size: 18px\">If interested in learning more, please contact <a href=\"mailto:yeh.team@sickkids.ca\">Tara Feltham<\/a> (416-813-7654 x 204757).<\/p>\n<p>&nbsp;<\/p>\n<p style=\"text-align: left;font-size: 18px\"><strong>Autoimmune Encephalitis (AE) Gene Expression Study<\/strong><\/p>\n<p style=\"text-align: left;font-size: 18px\">The goal of this study is to identify key molecular and cellular mechanisms of immune responses in childhood autoimmune encephalitides in order to help identify potential disease biomarkers and develop new targeted therapies. <a href=\"https:\/\/lab.research.sickkids.ca\/neuroinflamm\/research\/therapies-outcomes-in-autoimmune-encephalopathy\/\">Learn more here<\/a>.<\/p>\n<p style=\"text-align: left;font-size: 18px\">You may be eligible for this study if you:<\/p>\n<ul>\n<li style=\"font-size: 18px;text-align: left\">are under 18 years old;<\/li>\n<li style=\"font-size: 18px;text-align: left\">have been diagnosed with autoimmune encephalitis.<\/li>\n<\/ul>\n<p style=\"text-align: left;font-size: 18px\">If interested in learning more, please contact <a href=\"mailto:yeh.team@sickkids.ca\">Carmen Yea<\/a> (416-813-7654 x <strong>308828<\/strong>)<\/p>\n<p>[\/vc_column_text]<\/div><\/div>\n\n\t\t\t<\/div><div class=\"ult_exp_section_layer ult-adjust-bottom-margin  \" >\n\t\t<div id=\"uvc-exp-wrap-4844\" role=\"button\" tabindex=\"0\" aria-pressed=\"false\"  data-ultimate-target='#uvc-exp-wrap-4844'  data-responsive-json-new='{\"font-size\":\"desktop:25px;\",\"line-height\":\"desktop:50px;\"}'  class=\"ult_exp_section  ult-responsive \" style=\"color:#0068b3;background-color:#eaf2fb;font-weight:bold;  text-align:center;\" data-textcolor=\"#0068b3\"data-texthover=\"#db58a7\"data-icncolor=\"#333333\"data-ihover=\"#333333\"data-height=\"0\"data-cntbg=\"#eaf2fb\"data-cnthvrbg=\"rgba(219,88,167,0.06)\"data-headerbg=\"#eaf2fb\"data-headerhover=\"rgba(219,88,167,0.06)\"data-title=\"For MOG\"data-newtitle=\"For MOG\"data-icon=\"\"data-newicon=\"\"data-activeicon=\"#333333\"data-effect=\"slideToggle\"data-override=\"0\"data-activetitle=\"#db58a7\"data-activebg=\"rgba(219,88,167,0.06)\"data-img=\"\"data-newimg=\"\"><div  class=\"ult_exp_section-main \">\n\t\t\t\t\t<div class=\"ult_expheader\" >For MOG\n\t\t\t\t\t <\/div><\/div>\n\t\t\t\t<\/div><div class=\"ult_exp_content \" style=\"background-color:rgba(219,88,167,0.06);  \"><div class=\"ult_ecpsub_cont\" style=\" \" >[vc_column_text css=&#8221;.vc_custom_1644419191225{margin-top: -20px !important;padding-right: 20px !important;padding-left: 20px !important;}&#8221;]<\/p>\n<p style=\"text-align: left;font-size: 18px\"><strong>Satralizumab Drug Trial<\/strong><\/p>\n<p style=\"text-align: left;font-size: 18px\">To evaluate the efficacy of Satralizumab in relapsing pediatric patients with Myelin oligodendrocyte glycoprotein antibody-associated disease (MOGAD).<\/p>\n<p style=\"text-align: left;font-size: 18px\">You may be eligible for this study if you:<\/p>\n<ul>\n<li style=\"font-size: 18px;text-align: left\">are ages 12 and up;<\/li>\n<li style=\"font-size: 18px;text-align: left\">have been diagnosed with MOGAD<\/li>\n<\/ul>\n<p style=\"text-align: left;font-size: 18px\">If interested in learning more, please contact <a href=\"mailto:yeh.team@sickkids.ca\">Tara Feltham<\/a> (416-813-7654 x <strong>328190<\/strong>).<\/p>\n<p>[\/vc_column_text]<\/div><\/div>\n\n\t\t\t<\/div><div class=\"ult_exp_section_layer ult-adjust-bottom-margin  \" >\n\t\t<div id=\"uvc-exp-wrap-7677\" role=\"button\" tabindex=\"0\" aria-pressed=\"false\"  data-ultimate-target='#uvc-exp-wrap-7677'  data-responsive-json-new='{\"font-size\":\"desktop:25px;\",\"line-height\":\"desktop:50px;\"}'  class=\"ult_exp_section  ult-responsive \" style=\"color:#0068b3;background-color:#eaf2fb;font-weight:bold;  text-align:center;\" data-textcolor=\"#0068b3\"data-texthover=\"#db58a7\"data-icncolor=\"#333333\"data-ihover=\"#333333\"data-height=\"0\"data-cntbg=\"#eaf2fb\"data-cnthvrbg=\"rgba(219,88,167,0.06)\"data-headerbg=\"#eaf2fb\"data-headerhover=\"rgba(219,88,167,0.06)\"data-title=\"For Acute Flaccid Myelitis\/Paralysis (AFM\/AFP)\"data-newtitle=\"For Acute Flaccid Myelitis\/Paralysis (AFM\/AFP)\"data-icon=\"\"data-newicon=\"\"data-activeicon=\"#333333\"data-effect=\"slideToggle\"data-override=\"0\"data-activetitle=\"#db58a7\"data-activebg=\"rgba(219,88,167,0.06)\"data-img=\"\"data-newimg=\"\"><div  class=\"ult_exp_section-main \">\n\t\t\t\t\t<div class=\"ult_expheader\" >For Acute Flaccid Myelitis\/Paralysis (AFM\/AFP)\n\t\t\t\t\t <\/div><\/div>\n\t\t\t\t<\/div><div class=\"ult_exp_content \" style=\"background-color:rgba(219,88,167,0.06);  \"><div class=\"ult_ecpsub_cont\" style=\" \" >[vc_column_text css=&#8221;.vc_custom_1644419212568{margin-top: -20px !important;padding-right: 20px !important;padding-left: 20px !important;}&#8221;]<\/p>\n<p style=\"text-align: left;font-size: 18px\"><strong>Acute Flaccid Paralysis (AFP) in Canadian Children Study<\/strong><\/p>\n<p style=\"text-align: left;font-size: 18px\">This study is a national collaborative retrospective evaluation of clinical and MRI outcomes of children presenting with non-polio acute onset flaccid paresis (AFP). <a href=\"https:\/\/lab.research.sickkids.ca\/neuroinflamm\/research\/other-studies\/\">Learn more here<\/a>.<\/p>\n<p style=\"text-align: left;font-size: 18px\">You may be eligible for this study if you:<\/p>\n<ul>\n<li style=\"font-size: 18px;text-align: left\">are under 18 years old;<\/li>\n<li style=\"font-size: 18px;text-align: left\">have been diagnosed with AFP in the past 30 days.<\/li>\n<\/ul>\n<p style=\"text-align: left;font-size: 18px\">If interested in learning more, please contact <a href=\"mailto:yeh.team@sickkids.ca\">Carmen Yea<\/a> (416-813-7654 x <strong>308828<\/strong>).<\/p>\n<p>[\/vc_column_text]<\/div><\/div>\n\n\t\t\t<\/div><div class=\"ult_exp_section_layer ult-adjust-bottom-margin  \" >\n\t\t<div id=\"uvc-exp-wrap-9946\" role=\"button\" tabindex=\"0\" aria-pressed=\"false\"  data-ultimate-target='#uvc-exp-wrap-9946'  data-responsive-json-new='{\"font-size\":\"desktop:25px;\",\"line-height\":\"desktop:50px;\"}'  class=\"ult_exp_section  ult-responsive \" style=\"color:#0068b3;background-color:#eaf2fb;font-weight:bold;  text-align:center;\" data-textcolor=\"#0068b3\"data-texthover=\"#db58a7\"data-icncolor=\"#333333\"data-ihover=\"#333333\"data-height=\"0\"data-cntbg=\"#eaf2fb\"data-cnthvrbg=\"rgba(219,88,167,0.06)\"data-headerbg=\"#eaf2fb\"data-headerhover=\"rgba(219,88,167,0.06)\"data-title=\"For NMOSD\"data-newtitle=\"For NMOSD\"data-icon=\"\"data-newicon=\"\"data-activeicon=\"#333333\"data-effect=\"slideToggle\"data-override=\"0\"data-activetitle=\"#db58a7\"data-activebg=\"rgba(219,88,167,0.06)\"data-img=\"\"data-newimg=\"\"><div  class=\"ult_exp_section-main \">\n\t\t\t\t\t<div class=\"ult_expheader\" >For NMOSD\n\t\t\t\t\t <\/div><\/div>\n\t\t\t\t<\/div><div class=\"ult_exp_content \" style=\"background-color:rgba(219,88,167,0.06);  \"><div class=\"ult_ecpsub_cont\" style=\" \" >[vc_column_text css=&#8221;.vc_custom_1644419230976{margin-top: -20px !important;padding-right: 20px !important;padding-left: 20px !important;}&#8221;]<\/p>\n<p style=\"text-align: left;font-size: 18px\"><strong>Ravulizumab Drug Trial<\/strong><\/p>\n<p style=\"text-align: left;font-size: 18px\">To evaluate the efficacy of eculizumab in relapsing pediatric patients with Neuromyelitis Optica Spectrum Disorder (NMOSD).<\/p>\n<p style=\"text-align: left;font-size: 18px\">You may be eligible for this study if you:<\/p>\n<ul>\n<li style=\"font-size: 18px;text-align: left\">are between 2 and 18 years old;<\/li>\n<li style=\"font-size: 18px;text-align: left\">have been diagnosed with NMOSD<\/li>\n<\/ul>\n<p style=\"text-align: left;font-size: 18px\">If interested in learning more, please contact <a href=\"mailto:yeh.team@sickkids.ca\">Tara Feltham<\/a> (416-813-7654 x <strong>328190<\/strong>).<\/p>\n<p>[\/vc_column_text]<\/div><\/div>\n\n\t\t\t<\/div><div class=\"ult_exp_section_layer ult-adjust-bottom-margin  \" >\n\t\t<div id=\"uvc-exp-wrap-4172\" role=\"button\" tabindex=\"0\" aria-pressed=\"false\"  data-ultimate-target='#uvc-exp-wrap-4172'  data-responsive-json-new='{\"font-size\":\"desktop:25px;\",\"line-height\":\"desktop:50px;\"}'  class=\"ult_exp_section  ult-responsive \" style=\"color:#0068b3;background-color:#eaf2fb;font-weight:bold;  text-align:center;\" data-textcolor=\"#0068b3\"data-texthover=\"#db58a7\"data-icncolor=\"#333333\"data-ihover=\"#333333\"data-height=\"0\"data-cntbg=\"#eaf2fb\"data-cnthvrbg=\"rgba(219,88,167,0.06)\"data-headerbg=\"#eaf2fb\"data-headerhover=\"rgba(219,88,167,0.06)\"data-title=\"For All Neuroinflammatory Conditions\"data-newtitle=\"For All Neuroinflammatory Conditions\"data-icon=\"\"data-newicon=\"\"data-activeicon=\"#333333\"data-effect=\"slideToggle\"data-override=\"0\"data-activetitle=\"#db58a7\"data-activebg=\"rgba(219,88,167,0.06)\"data-img=\"\"data-newimg=\"\"><div  class=\"ult_exp_section-main \">\n\t\t\t\t\t<div class=\"ult_expheader\" >For All Neuroinflammatory Conditions\n\t\t\t\t\t <\/div><\/div>\n\t\t\t\t<\/div><div class=\"ult_exp_content \" style=\"background-color:rgba(219,88,167,0.06);  \"><div class=\"ult_ecpsub_cont\" style=\" \" >[vc_column_text css=&#8221;.vc_custom_1644419083235{margin-top: -20px !important;padding-right: 20px !important;padding-left: 20px !important;}&#8221;]<\/p>\n<p>&nbsp;<\/p>\n<p style=\"text-align: left;font-size: 18px\"><strong>Neuroinflammatory Patient Registry Study<\/strong><\/p>\n<p style=\"text-align: left;font-size: 18px\">The purpose of the Registry is to collect information on children with neuroinflammatory disorders for use in research aimed to increase our knowledge of childhood neuroinflammation and to help doctors develop better ways to diagnose and treat children with this rare condition. <a href=\"https:\/\/lab.research.sickkids.ca\/neuroinflamm\/research\/other-studies\/\">Learn more here<\/a>.<\/p>\n<p style=\"text-align: left;font-size: 18px\">You may be eligible for this study if you:<\/p>\n<ul>\n<li style=\"font-size: 18px;text-align: left\">are under 18 years old;<\/li>\n<li style=\"font-size: 18px;text-align: left\">have been diagnosed with a neuroinflammatory disorder or a suspected neuroinflammatory disorder.<\/li>\n<\/ul>\n<p>[\/vc_column_text]<\/div><\/div>\n\n\t\t\t<\/div>\n\t\t\t<\/div>\n\t\t\t<div  class=\"ult_tabitemname\"  >\n\t\t\t\t<div class=\"ult_exp_section_layer ult-adjust-bottom-margin  \" >\n\t\t<div id=\"uvc-exp-wrap-6121\" role=\"button\" tabindex=\"0\" aria-pressed=\"false\"  data-ultimate-target='#uvc-exp-wrap-6121'  data-responsive-json-new='{\"font-size\":\"desktop:25px;\",\"line-height\":\"desktop:50px;\"}'  class=\"ult_exp_section  ult-responsive \" style=\"color:#0068b3;background-color:#eaf2fb;font-weight:bold;  text-align:center;\" data-textcolor=\"#0068b3\"data-texthover=\"#db58a7\"data-icncolor=\"#333333\"data-ihover=\"#333333\"data-height=\"0\"data-cntbg=\"#eaf2fb\"data-cnthvrbg=\"rgba(219,88,167,0.06)\"data-headerbg=\"#eaf2fb\"data-headerhover=\"rgba(219,88,167,0.06)\"data-title=\"LIFESTYLE OUTCOMES\"data-newtitle=\"LIFESTYLE OUTCOMES\"data-icon=\"\"data-newicon=\"\"data-activeicon=\"#333333\"data-effect=\"slideToggle\"data-override=\"0\"data-activetitle=\"#db58a7\"data-activebg=\"rgba(219,88,167,0.06)\"data-img=\"\"data-newimg=\"\"><div  class=\"ult_exp_section-main \">\n\t\t\t\t\t<div class=\"ult_expheader\" >LIFESTYLE OUTCOMES\n\t\t\t\t\t <\/div><\/div>\n\t\t\t\t<\/div><div class=\"ult_exp_content \" style=\"background-color:rgba(219,88,167,0.06);  \"><div class=\"ult_ecpsub_cont\" style=\" \" >[vc_column_text css=&#8221;.vc_custom_1627662122087{margin-top: -20px !important;padding-right: 20px !important;padding-left: 20px !important;}&#8221;]<\/p>\n<p style=\"font-size: 18px;text-align: center\">Check back later for new opportunities!<\/p>\n<p>[\/vc_column_text]<\/div><\/div>\n\n\t\t\t<\/div><div class=\"ult_exp_section_layer ult-adjust-bottom-margin  \" >\n\t\t<div id=\"uvc-exp-wrap-6010\" role=\"button\" tabindex=\"0\" aria-pressed=\"false\"  data-ultimate-target='#uvc-exp-wrap-6010'  data-responsive-json-new='{\"font-size\":\"desktop:25px;\",\"line-height\":\"desktop:50px;\"}'  class=\"ult_exp_section  ult-responsive \" style=\"color:#0068b3;background-color:#eaf2fb;font-weight:bold;  text-align:center;\" data-textcolor=\"#0068b3\"data-texthover=\"#db58a7\"data-icncolor=\"#333333\"data-ihover=\"#333333\"data-height=\"0\"data-cntbg=\"#eaf2fb\"data-cnthvrbg=\"rgba(219,88,167,0.06)\"data-headerbg=\"#eaf2fb\"data-headerhover=\"rgba(219,88,167,0.06)\"data-title=\"VISUAL AND NEURO-COGNITIVE OUTCOMES\"data-newtitle=\"VISUAL AND NEURO-COGNITIVE OUTCOMES\"data-icon=\"\"data-newicon=\"\"data-activeicon=\"#333333\"data-effect=\"slideToggle\"data-override=\"0\"data-activetitle=\"#db58a7\"data-activebg=\"rgba(219,88,167,0.06)\"data-img=\"\"data-newimg=\"\"><div  class=\"ult_exp_section-main \">\n\t\t\t\t\t<div class=\"ult_expheader\" >VISUAL AND NEURO-COGNITIVE OUTCOMES\n\t\t\t\t\t <\/div><\/div>\n\t\t\t\t<\/div><div class=\"ult_exp_content \" style=\"background-color:rgba(219,88,167,0.06);  \"><div class=\"ult_ecpsub_cont\" style=\" \" >[vc_column_text css=&#8221;.vc_custom_1627661969836{margin-top: -20px !important;padding-right: 20px !important;padding-left: 20px !important;}&#8221;]<\/p>\n<p>&nbsp;<\/p>\n<p style=\"text-align: left;font-size: 18px\"><strong>Autoimmune Encephalitis (AE) Gene Expression Study<\/strong><\/p>\n<p style=\"text-align: left;font-size: 18px\">The goal of this study is to identify key molecular and cellular mechanisms of immune responses in childhood autoimmune encephalitides in order to help identify potential disease biomarkers and develop new targeted therapies. <a href=\"https:\/\/lab.research.sickkids.ca\/neuroinflamm\/research\/therapies-outcomes-in-autoimmune-encephalopathy\/\">Learn more here<\/a>.<\/p>\n<p style=\"text-align: left;font-size: 18px\">You may be eligible for this study as a <strong>healthy control participant<\/strong> if you:<\/p>\n<ul>\n<li style=\"font-size: 18px;text-align: left\">are under 18 years old;<\/li>\n<li style=\"font-size: 18px;text-align: left\">have no significant medical history.<\/li>\n<\/ul>\n<p style=\"text-align: left;font-size: 18px\">If interested in learning more, please contact <a href=\"mailto:yeh.team@sickkids.ca\">Carmen Yea<\/a> (416-813-7654 x 308828) or <a href=\"mailto:yeh.team@sickkids.ca\">Olivia Lau<\/a> (416-813-7654 x 328577).<\/p>\n<p>[\/vc_column_text]<\/div><\/div>\n\n\t\t\t<\/div><div class=\"ult_exp_section_layer ult-adjust-bottom-margin  \" >\n\t\t<div id=\"uvc-exp-wrap-2734\" role=\"button\" tabindex=\"0\" aria-pressed=\"false\"  data-ultimate-target='#uvc-exp-wrap-2734'  data-responsive-json-new='{\"font-size\":\"desktop:25px;\",\"line-height\":\"desktop:50px;\"}'  class=\"ult_exp_section  ult-responsive \" style=\"color:#0068b3;background-color:#eaf2fb;font-weight:bold;  text-align:center;\" data-textcolor=\"#0068b3\"data-texthover=\"#db58a7\"data-icncolor=\"#333333\"data-ihover=\"#333333\"data-height=\"0\"data-cntbg=\"#eaf2fb\"data-cnthvrbg=\"rgba(219,88,167,0.06)\"data-headerbg=\"#eaf2fb\"data-headerhover=\"rgba(219,88,167,0.06)\"data-title=\"OTHER STUDIES\"data-newtitle=\"OTHER STUDIES\"data-icon=\"\"data-newicon=\"\"data-activeicon=\"#333333\"data-effect=\"slideToggle\"data-override=\"0\"data-activetitle=\"#db58a7\"data-activebg=\"rgba(219,88,167,0.06)\"data-img=\"\"data-newimg=\"\"><div  class=\"ult_exp_section-main \">\n\t\t\t\t\t<div class=\"ult_expheader\" >OTHER STUDIES\n\t\t\t\t\t <\/div><\/div>\n\t\t\t\t<\/div><div class=\"ult_exp_content \" style=\"background-color:rgba(219,88,167,0.06);  \"><div class=\"ult_ecpsub_cont\" style=\" \" >[vc_column_text css=&#8221;.vc_custom_1627662136143{margin-top: -20px !important;padding-right: 20px !important;padding-left: 20px !important;}&#8221;]<\/p>\n<p style=\"font-size: 18px;text-align: center\">Check back later for new opportunities!<\/p>\n<p>[\/vc_column_text]<\/div><\/div>\n\n\t\t\t<\/div>\n\t\t\t<\/div><\/div><\/div><\/div><div class=\"ult_acord advanced-tabs-desc-wrap-8715\">\n   <div class=\"ult-tabto-accordion \" style=\"width:;\"\n    data-titlecolor=\"#74777b\"  data-titlebg=\"#e7ecea\"\n     data-titlehoverbg=\"#4f90d1\" data-titlehovercolor=\"#ffffff\" data-animation=\"Slide-Zoom\"\n     data-activetitle=\"#ffffff\" data-activeicon=\"\" data-activebg=\"#4f90d1\" data-scroll = \"on\" data-activeindex=\"1\" >\n     <dl><dt class=\"\">\n        \t<a class=\"ult-tabto-actitle withBorder ult_a\" id=\"1628818368354-7\" style=\"color:#74777b;;background-color:#e7ecea;border-bottom-color:transparent;border-bottom-width:0px;border-bottom-style:solid;\" href=\"#1628818368354-7\">\n        \t\t<i class=\"accordion-icon\"><\/i>\n        \t\t\t<span class=\"ult_tab_main ult_ac_mainBoth\">\n\t\t\t\t\t   <span  data-ultimate-target='#advanced-tabs-wrap-6661 .ult-span-text'  data-responsive-json-new='{\"font-size\":\"desktop:15px;\",\"line-height\":\"\"}'  class=\"ult-span-text ult_acordian-text ult-responsive\" style=\";color:inherit \" >Patient Opportunities<\/span>\n\t\t\t\t\t<\/span>\n\t\t\t\t\t   <div class=\"aio-icon none \" style=\"color:#74777b;font-size:15px;\" data-iconcolor=\"#74777b\" data-iconhover=\"#ffffff\">\n\t\t\t\t\t   <i class=\"    ult_tab_icon\"  ><\/i>\n\t\t\t\t\t   <\/div>\n\t\t\t\t\t<\/a><\/dt>\n            \t\t<dd class=\"ult-tabto-accordionItem ult-tabto-accolapsed\">\n\t\t\t            <div class=\"ult-tabto-acontent\" style=\"color:#74777b;\">\n\t\t\t               <div class=\"ult_exp_section_layer ult-adjust-bottom-margin  \" >\n\t\t<div id=\"uvc-exp-wrap-5519\" role=\"button\" tabindex=\"0\" aria-pressed=\"false\"  data-ultimate-target='#uvc-exp-wrap-5519'  data-responsive-json-new='{\"font-size\":\"desktop:25px;\",\"line-height\":\"desktop:50px;\"}'  class=\"ult_exp_section  ult-responsive \" style=\"color:#0068b3;background-color:#eaf2fb;font-weight:bold;  text-align:center;\" data-textcolor=\"#0068b3\"data-texthover=\"#db58a7\"data-icncolor=\"#333333\"data-ihover=\"#333333\"data-height=\"0\"data-cntbg=\"#eaf2fb\"data-cnthvrbg=\"rgba(219,88,167,0.06)\"data-headerbg=\"#eaf2fb\"data-headerhover=\"rgba(219,88,167,0.06)\"data-title=\"For Multiple Sclerosis\"data-newtitle=\"For Multiple Sclerosis\"data-icon=\"\"data-newicon=\"\"data-activeicon=\"#333333\"data-effect=\"slideToggle\"data-override=\"0\"data-activetitle=\"#db58a7\"data-activebg=\"rgba(219,88,167,0.06)\"data-img=\"\"data-newimg=\"\"><div  class=\"ult_exp_section-main \">\n\t\t\t\t\t<div class=\"ult_expheader\" >For Multiple Sclerosis\n\t\t\t\t\t <\/div><\/div>\n\t\t\t\t<\/div><div class=\"ult_exp_content \" style=\"background-color:rgba(219,88,167,0.06);  \"><div class=\"ult_ecpsub_cont\" style=\" \" >[vc_column_text css=&#8221;.vc_custom_1644419278134{margin-top: -20px !important;padding-right: 20px !important;padding-left: 20px !important;}&#8221;]<\/p>\n<p>&nbsp;<\/p>\n<p style=\"text-align: left;font-size: 18px\"><strong>Metformin in Children and Young Adults with MS Study<\/strong><\/p>\n<p style=\"text-align: left;font-size: 18px\">We want to see if we can repair damaged myelin in children and young adults with MS using a drug called metformin. Previous research has shown that metformin helps repair myelin in mice and may associate with decreased relapses in adults with MS and metabolic syndromes. <a href=\"https:\/\/lab.research.sickkids.ca\/neuroinflamm\/research\/visual-neurocognitive-outcomes\/\">Learn more here<\/a>.<\/p>\n<p style=\"text-align: left;font-size: 18px\">You may be eligible for this study if you:<\/p>\n<ul>\n<li style=\"font-size: 18px;text-align: left\">are between 10 and 26 years old;<\/li>\n<li style=\"font-size: 18px;text-align: left\">have been diagnosed with MS.<\/li>\n<\/ul>\n<p style=\"text-align: left;font-size: 18px\">If interested in learning more, please contact <a href=\"mailto:yeh.team@sickkids.ca\">Brenna Wong<\/a> (416-813-7654 x <strong>415744<\/strong>).<\/p>\n<p>&nbsp;<\/p>\n<p style=\"text-align: left;font-size: 18px\"><strong>Participation, Environment, And Key Clinical and Health Outcomes in Children with Multiple Sclerosis (PEACH)<\/strong><\/p>\n<p style=\"text-align: left;font-size: 18px\">We are currently conducting and recruiting for a new study looking at the relationship between participation in home, school and community activities, and mental health in children and youth with multiple sclerosis (MS). We hope to use this information to better understand how neuroinflammatory disease can affect a child\u2019s mental health and ability to participate in activities at home, school and in the community. Over the course of the study, we hope to also identify what other factors affect their ability to participate in these activities.<\/p>\n<p style=\"text-align: left;font-size: 18px\">You may be eligible for this study if you:<\/p>\n<ul>\n<li style=\"font-size: 18px;text-align: left\">are between 5 and 17 years old;<\/li>\n<li style=\"font-size: 18px;text-align: left\">have been diagnosed with MS.<\/li>\n<\/ul>\n<p style=\"text-align: left;font-size: 18px\">If interested in learning more, please contact <a href=\"paul.yoo@sickkids.ca\">Paul Yoo<\/a> (416-813-7654 x <strong>328190<\/strong>).<\/p>\n<p>&nbsp;<\/p>\n<p>[\/vc_column_text]<\/div><\/div>\n\n\t\t\t<\/div><div class=\"ult_exp_section_layer ult-adjust-bottom-margin  \" >\n\t\t<div id=\"uvc-exp-wrap-1635\" role=\"button\" tabindex=\"0\" aria-pressed=\"false\"  data-ultimate-target='#uvc-exp-wrap-1635'  data-responsive-json-new='{\"font-size\":\"desktop:25px;\",\"line-height\":\"desktop:50px;\"}'  class=\"ult_exp_section  ult-responsive \" style=\"color:#0068b3;background-color:#eaf2fb;font-weight:bold;  text-align:center;\" data-textcolor=\"#0068b3\"data-texthover=\"#db58a7\"data-icncolor=\"#333333\"data-ihover=\"#333333\"data-height=\"0\"data-cntbg=\"#eaf2fb\"data-cnthvrbg=\"rgba(219,88,167,0.06)\"data-headerbg=\"#eaf2fb\"data-headerhover=\"rgba(219,88,167,0.06)\"data-title=\"For OMAS\"data-newtitle=\"For OMAS\"data-icon=\"\"data-newicon=\"\"data-activeicon=\"#333333\"data-effect=\"slideToggle\"data-override=\"0\"data-activetitle=\"#db58a7\"data-activebg=\"rgba(219,88,167,0.06)\"data-img=\"\"data-newimg=\"\"><div  class=\"ult_exp_section-main \">\n\t\t\t\t\t<div class=\"ult_expheader\" >For OMAS\n\t\t\t\t\t <\/div><\/div>\n\t\t\t\t<\/div><div class=\"ult_exp_content \" style=\"background-color:rgba(219,88,167,0.06);  \"><div class=\"ult_ecpsub_cont\" style=\" \" >[vc_column_text css=&#8221;.vc_custom_1644419191225{margin-top: -20px !important;padding-right: 20px !important;padding-left: 20px !important;}&#8221;]<\/p>\n<p style=\"text-align: left;font-size: 18px\"><strong>OMAS Study<\/strong><\/p>\n<p style=\"text-align: left;font-size: 18px\">The goal of this study is to investigate eye movement outcomes in relation to brain volume, cognitive function, and disease severity in pediatric OMAS. <a href=\"https:\/\/lab.research.sickkids.ca\/neuroinflamm\/research\/visual-neurocognitive-outcomes\/\">Learn more here<\/a>.<\/p>\n<p style=\"text-align: left;font-size: 18px\">You may be eligible for this study if you:<\/p>\n<ul>\n<li style=\"font-size: 18px;text-align: left\">are between 6 and 18 years old;<\/li>\n<li style=\"font-size: 18px;text-align: left\">have been diagnosed with OMAS.<\/li>\n<\/ul>\n<p style=\"text-align: left;font-size: 18px\">If interested in learning more, please contact <a href=\"mailto:yeh.team@sickkids.ca\">Tara Feltham<\/a> (416-813-7654 x 204757).<\/p>\n<p>&nbsp;<\/p>\n<p style=\"text-align: left;font-size: 18px\"><strong>Autoimmune Encephalitis (AE) Gene Expression Study<\/strong><\/p>\n<p style=\"text-align: left;font-size: 18px\">The goal of this study is to identify key molecular and cellular mechanisms of immune responses in childhood autoimmune encephalitides in order to help identify potential disease biomarkers and develop new targeted therapies. <a href=\"https:\/\/lab.research.sickkids.ca\/neuroinflamm\/research\/therapies-outcomes-in-autoimmune-encephalopathy\/\">Learn more here<\/a>.<\/p>\n<p style=\"text-align: left;font-size: 18px\">You may be eligible for this study if you:<\/p>\n<ul>\n<li style=\"font-size: 18px;text-align: left\">are under 18 years old;<\/li>\n<li style=\"font-size: 18px;text-align: left\">have been diagnosed with autoimmune encephalitis.<\/li>\n<\/ul>\n<p style=\"text-align: left;font-size: 18px\">If interested in learning more, please contact <a href=\"mailto:yeh.team@sickkids.ca\">Carmen Yea<\/a> (416-813-7654 x <strong>308828<\/strong>)<\/p>\n<p>[\/vc_column_text]<\/div><\/div>\n\n\t\t\t<\/div><div class=\"ult_exp_section_layer ult-adjust-bottom-margin  \" >\n\t\t<div id=\"uvc-exp-wrap-2386\" role=\"button\" tabindex=\"0\" aria-pressed=\"false\"  data-ultimate-target='#uvc-exp-wrap-2386'  data-responsive-json-new='{\"font-size\":\"desktop:25px;\",\"line-height\":\"desktop:50px;\"}'  class=\"ult_exp_section  ult-responsive \" style=\"color:#0068b3;background-color:#eaf2fb;font-weight:bold;  text-align:center;\" data-textcolor=\"#0068b3\"data-texthover=\"#db58a7\"data-icncolor=\"#333333\"data-ihover=\"#333333\"data-height=\"0\"data-cntbg=\"#eaf2fb\"data-cnthvrbg=\"rgba(219,88,167,0.06)\"data-headerbg=\"#eaf2fb\"data-headerhover=\"rgba(219,88,167,0.06)\"data-title=\"For MOG\"data-newtitle=\"For MOG\"data-icon=\"\"data-newicon=\"\"data-activeicon=\"#333333\"data-effect=\"slideToggle\"data-override=\"0\"data-activetitle=\"#db58a7\"data-activebg=\"rgba(219,88,167,0.06)\"data-img=\"\"data-newimg=\"\"><div  class=\"ult_exp_section-main \">\n\t\t\t\t\t<div class=\"ult_expheader\" >For MOG\n\t\t\t\t\t <\/div><\/div>\n\t\t\t\t<\/div><div class=\"ult_exp_content \" style=\"background-color:rgba(219,88,167,0.06);  \"><div class=\"ult_ecpsub_cont\" style=\" \" >[vc_column_text css=&#8221;.vc_custom_1644419191225{margin-top: -20px !important;padding-right: 20px !important;padding-left: 20px !important;}&#8221;]<\/p>\n<p style=\"text-align: left;font-size: 18px\"><strong>Satralizumab Drug Trial<\/strong><\/p>\n<p style=\"text-align: left;font-size: 18px\">To evaluate the efficacy of Satralizumab in relapsing pediatric patients with Myelin oligodendrocyte glycoprotein antibody-associated disease (MOGAD).<\/p>\n<p style=\"text-align: left;font-size: 18px\">You may be eligible for this study if you:<\/p>\n<ul>\n<li style=\"font-size: 18px;text-align: left\">are ages 12 and up;<\/li>\n<li style=\"font-size: 18px;text-align: left\">have been diagnosed with MOGAD<\/li>\n<\/ul>\n<p style=\"text-align: left;font-size: 18px\">If interested in learning more, please contact <a href=\"mailto:yeh.team@sickkids.ca\">Tara Feltham<\/a> (416-813-7654 x <strong>328190<\/strong>).<\/p>\n<p>[\/vc_column_text]<\/div><\/div>\n\n\t\t\t<\/div><div class=\"ult_exp_section_layer ult-adjust-bottom-margin  \" >\n\t\t<div id=\"uvc-exp-wrap-8631\" role=\"button\" tabindex=\"0\" aria-pressed=\"false\"  data-ultimate-target='#uvc-exp-wrap-8631'  data-responsive-json-new='{\"font-size\":\"desktop:25px;\",\"line-height\":\"desktop:50px;\"}'  class=\"ult_exp_section  ult-responsive \" style=\"color:#0068b3;background-color:#eaf2fb;font-weight:bold;  text-align:center;\" data-textcolor=\"#0068b3\"data-texthover=\"#db58a7\"data-icncolor=\"#333333\"data-ihover=\"#333333\"data-height=\"0\"data-cntbg=\"#eaf2fb\"data-cnthvrbg=\"rgba(219,88,167,0.06)\"data-headerbg=\"#eaf2fb\"data-headerhover=\"rgba(219,88,167,0.06)\"data-title=\"For Acute Flaccid Myelitis\/Paralysis (AFM\/AFP)\"data-newtitle=\"For Acute Flaccid Myelitis\/Paralysis (AFM\/AFP)\"data-icon=\"\"data-newicon=\"\"data-activeicon=\"#333333\"data-effect=\"slideToggle\"data-override=\"0\"data-activetitle=\"#db58a7\"data-activebg=\"rgba(219,88,167,0.06)\"data-img=\"\"data-newimg=\"\"><div  class=\"ult_exp_section-main \">\n\t\t\t\t\t<div class=\"ult_expheader\" >For Acute Flaccid Myelitis\/Paralysis (AFM\/AFP)\n\t\t\t\t\t <\/div><\/div>\n\t\t\t\t<\/div><div class=\"ult_exp_content \" style=\"background-color:rgba(219,88,167,0.06);  \"><div class=\"ult_ecpsub_cont\" style=\" \" >[vc_column_text css=&#8221;.vc_custom_1644419212568{margin-top: -20px !important;padding-right: 20px !important;padding-left: 20px !important;}&#8221;]<\/p>\n<p style=\"text-align: left;font-size: 18px\"><strong>Acute Flaccid Paralysis (AFP) in Canadian Children Study<\/strong><\/p>\n<p style=\"text-align: left;font-size: 18px\">This study is a national collaborative retrospective evaluation of clinical and MRI outcomes of children presenting with non-polio acute onset flaccid paresis (AFP). <a href=\"https:\/\/lab.research.sickkids.ca\/neuroinflamm\/research\/other-studies\/\">Learn more here<\/a>.<\/p>\n<p style=\"text-align: left;font-size: 18px\">You may be eligible for this study if you:<\/p>\n<ul>\n<li style=\"font-size: 18px;text-align: left\">are under 18 years old;<\/li>\n<li style=\"font-size: 18px;text-align: left\">have been diagnosed with AFP in the past 30 days.<\/li>\n<\/ul>\n<p style=\"text-align: left;font-size: 18px\">If interested in learning more, please contact <a href=\"mailto:yeh.team@sickkids.ca\">Carmen Yea<\/a> (416-813-7654 x <strong>308828<\/strong>).<\/p>\n<p>[\/vc_column_text]<\/div><\/div>\n\n\t\t\t<\/div><div class=\"ult_exp_section_layer ult-adjust-bottom-margin  \" >\n\t\t<div id=\"uvc-exp-wrap-3202\" role=\"button\" tabindex=\"0\" aria-pressed=\"false\"  data-ultimate-target='#uvc-exp-wrap-3202'  data-responsive-json-new='{\"font-size\":\"desktop:25px;\",\"line-height\":\"desktop:50px;\"}'  class=\"ult_exp_section  ult-responsive \" style=\"color:#0068b3;background-color:#eaf2fb;font-weight:bold;  text-align:center;\" data-textcolor=\"#0068b3\"data-texthover=\"#db58a7\"data-icncolor=\"#333333\"data-ihover=\"#333333\"data-height=\"0\"data-cntbg=\"#eaf2fb\"data-cnthvrbg=\"rgba(219,88,167,0.06)\"data-headerbg=\"#eaf2fb\"data-headerhover=\"rgba(219,88,167,0.06)\"data-title=\"For NMOSD\"data-newtitle=\"For NMOSD\"data-icon=\"\"data-newicon=\"\"data-activeicon=\"#333333\"data-effect=\"slideToggle\"data-override=\"0\"data-activetitle=\"#db58a7\"data-activebg=\"rgba(219,88,167,0.06)\"data-img=\"\"data-newimg=\"\"><div  class=\"ult_exp_section-main \">\n\t\t\t\t\t<div class=\"ult_expheader\" >For NMOSD\n\t\t\t\t\t <\/div><\/div>\n\t\t\t\t<\/div><div class=\"ult_exp_content \" style=\"background-color:rgba(219,88,167,0.06);  \"><div class=\"ult_ecpsub_cont\" style=\" \" >[vc_column_text css=&#8221;.vc_custom_1644419230976{margin-top: -20px !important;padding-right: 20px !important;padding-left: 20px !important;}&#8221;]<\/p>\n<p style=\"text-align: left;font-size: 18px\"><strong>Ravulizumab Drug Trial<\/strong><\/p>\n<p style=\"text-align: left;font-size: 18px\">To evaluate the efficacy of eculizumab in relapsing pediatric patients with Neuromyelitis Optica Spectrum Disorder (NMOSD).<\/p>\n<p style=\"text-align: left;font-size: 18px\">You may be eligible for this study if you:<\/p>\n<ul>\n<li style=\"font-size: 18px;text-align: left\">are between 2 and 18 years old;<\/li>\n<li style=\"font-size: 18px;text-align: left\">have been diagnosed with NMOSD<\/li>\n<\/ul>\n<p style=\"text-align: left;font-size: 18px\">If interested in learning more, please contact <a href=\"mailto:yeh.team@sickkids.ca\">Tara Feltham<\/a> (416-813-7654 x <strong>328190<\/strong>).<\/p>\n<p>[\/vc_column_text]<\/div><\/div>\n\n\t\t\t<\/div><div class=\"ult_exp_section_layer ult-adjust-bottom-margin  \" >\n\t\t<div id=\"uvc-exp-wrap-2750\" role=\"button\" tabindex=\"0\" aria-pressed=\"false\"  data-ultimate-target='#uvc-exp-wrap-2750'  data-responsive-json-new='{\"font-size\":\"desktop:25px;\",\"line-height\":\"desktop:50px;\"}'  class=\"ult_exp_section  ult-responsive \" style=\"color:#0068b3;background-color:#eaf2fb;font-weight:bold;  text-align:center;\" data-textcolor=\"#0068b3\"data-texthover=\"#db58a7\"data-icncolor=\"#333333\"data-ihover=\"#333333\"data-height=\"0\"data-cntbg=\"#eaf2fb\"data-cnthvrbg=\"rgba(219,88,167,0.06)\"data-headerbg=\"#eaf2fb\"data-headerhover=\"rgba(219,88,167,0.06)\"data-title=\"For All Neuroinflammatory Conditions\"data-newtitle=\"For All Neuroinflammatory Conditions\"data-icon=\"\"data-newicon=\"\"data-activeicon=\"#333333\"data-effect=\"slideToggle\"data-override=\"0\"data-activetitle=\"#db58a7\"data-activebg=\"rgba(219,88,167,0.06)\"data-img=\"\"data-newimg=\"\"><div  class=\"ult_exp_section-main \">\n\t\t\t\t\t<div class=\"ult_expheader\" >For All Neuroinflammatory Conditions\n\t\t\t\t\t <\/div><\/div>\n\t\t\t\t<\/div><div class=\"ult_exp_content \" style=\"background-color:rgba(219,88,167,0.06);  \"><div class=\"ult_ecpsub_cont\" style=\" \" >[vc_column_text css=&#8221;.vc_custom_1644419083235{margin-top: -20px !important;padding-right: 20px !important;padding-left: 20px !important;}&#8221;]<\/p>\n<p>&nbsp;<\/p>\n<p style=\"text-align: left;font-size: 18px\"><strong>Neuroinflammatory Patient Registry Study<\/strong><\/p>\n<p style=\"text-align: left;font-size: 18px\">The purpose of the Registry is to collect information on children with neuroinflammatory disorders for use in research aimed to increase our knowledge of childhood neuroinflammation and to help doctors develop better ways to diagnose and treat children with this rare condition. <a href=\"https:\/\/lab.research.sickkids.ca\/neuroinflamm\/research\/other-studies\/\">Learn more here<\/a>.<\/p>\n<p style=\"text-align: left;font-size: 18px\">You may be eligible for this study if you:<\/p>\n<ul>\n<li style=\"font-size: 18px;text-align: left\">are under 18 years old;<\/li>\n<li style=\"font-size: 18px;text-align: left\">have been diagnosed with a neuroinflammatory disorder or a suspected neuroinflammatory disorder.<\/li>\n<\/ul>\n<p>[\/vc_column_text]<\/div><\/div>\n\n\t\t\t<\/div>\n\t\t\t            <\/div>\n        \t<\/dd><dt class=\"\">\n        \t<a class=\"ult-tabto-actitle withBorder ult_a\" id=\"tab_hc\" style=\"color:#74777b;;background-color:#e7ecea;border-bottom-color:transparent;border-bottom-width:0px;border-bottom-style:solid;border-bottom-color:transparent;border-bottom-width:0px;border-bottom-style:solid;\" href=\"#tab_hc\">\n        \t\t<i class=\"accordion-icon\"><\/i>\n        \t\t\t<span class=\"ult_tab_main ult_ac_mainBoth\">\n\t\t\t\t\t   <span  data-ultimate-target='#advanced-tabs-wrap-6661 .ult-span-text'  data-responsive-json-new='{\"font-size\":\"desktop:15px;\",\"line-height\":\"\"}'  class=\"ult-span-text ult_acordian-text ult-responsive\" style=\";color:inherit \" >Healthy Control Opportunities<\/span>\n\t\t\t\t\t<\/span>\n\t\t\t\t\t   <div class=\"aio-icon none \" style=\"color:#74777b;font-size:15px;\" data-iconcolor=\"#74777b\" data-iconhover=\"#ffffff\">\n\t\t\t\t\t   <i class=\"    ult_tab_icon\"  ><\/i>\n\t\t\t\t\t   <\/div>\n\t\t\t\t\t<\/a><\/dt>\n            \t\t<dd class=\"ult-tabto-accordionItem ult-tabto-accolapsed\">\n\t\t\t            <div class=\"ult-tabto-acontent\" style=\"color:#74777b;\">\n\t\t\t               <div class=\"ult_exp_section_layer ult-adjust-bottom-margin  \" >\n\t\t<div id=\"uvc-exp-wrap-4784\" role=\"button\" tabindex=\"0\" aria-pressed=\"false\"  data-ultimate-target='#uvc-exp-wrap-4784'  data-responsive-json-new='{\"font-size\":\"desktop:25px;\",\"line-height\":\"desktop:50px;\"}'  class=\"ult_exp_section  ult-responsive \" style=\"color:#0068b3;background-color:#eaf2fb;font-weight:bold;  text-align:center;\" data-textcolor=\"#0068b3\"data-texthover=\"#db58a7\"data-icncolor=\"#333333\"data-ihover=\"#333333\"data-height=\"0\"data-cntbg=\"#eaf2fb\"data-cnthvrbg=\"rgba(219,88,167,0.06)\"data-headerbg=\"#eaf2fb\"data-headerhover=\"rgba(219,88,167,0.06)\"data-title=\"LIFESTYLE OUTCOMES\"data-newtitle=\"LIFESTYLE OUTCOMES\"data-icon=\"\"data-newicon=\"\"data-activeicon=\"#333333\"data-effect=\"slideToggle\"data-override=\"0\"data-activetitle=\"#db58a7\"data-activebg=\"rgba(219,88,167,0.06)\"data-img=\"\"data-newimg=\"\"><div  class=\"ult_exp_section-main \">\n\t\t\t\t\t<div class=\"ult_expheader\" >LIFESTYLE OUTCOMES\n\t\t\t\t\t <\/div><\/div>\n\t\t\t\t<\/div><div class=\"ult_exp_content \" style=\"background-color:rgba(219,88,167,0.06);  \"><div class=\"ult_ecpsub_cont\" style=\" \" >[vc_column_text css=&#8221;.vc_custom_1627662122087{margin-top: -20px !important;padding-right: 20px !important;padding-left: 20px !important;}&#8221;]<\/p>\n<p style=\"font-size: 18px;text-align: center\">Check back later for new opportunities!<\/p>\n<p>[\/vc_column_text]<\/div><\/div>\n\n\t\t\t<\/div><div class=\"ult_exp_section_layer ult-adjust-bottom-margin  \" >\n\t\t<div id=\"uvc-exp-wrap-6871\" role=\"button\" tabindex=\"0\" aria-pressed=\"false\"  data-ultimate-target='#uvc-exp-wrap-6871'  data-responsive-json-new='{\"font-size\":\"desktop:25px;\",\"line-height\":\"desktop:50px;\"}'  class=\"ult_exp_section  ult-responsive \" style=\"color:#0068b3;background-color:#eaf2fb;font-weight:bold;  text-align:center;\" data-textcolor=\"#0068b3\"data-texthover=\"#db58a7\"data-icncolor=\"#333333\"data-ihover=\"#333333\"data-height=\"0\"data-cntbg=\"#eaf2fb\"data-cnthvrbg=\"rgba(219,88,167,0.06)\"data-headerbg=\"#eaf2fb\"data-headerhover=\"rgba(219,88,167,0.06)\"data-title=\"VISUAL AND NEURO-COGNITIVE OUTCOMES\"data-newtitle=\"VISUAL AND NEURO-COGNITIVE OUTCOMES\"data-icon=\"\"data-newicon=\"\"data-activeicon=\"#333333\"data-effect=\"slideToggle\"data-override=\"0\"data-activetitle=\"#db58a7\"data-activebg=\"rgba(219,88,167,0.06)\"data-img=\"\"data-newimg=\"\"><div  class=\"ult_exp_section-main \">\n\t\t\t\t\t<div class=\"ult_expheader\" >VISUAL AND NEURO-COGNITIVE OUTCOMES\n\t\t\t\t\t <\/div><\/div>\n\t\t\t\t<\/div><div class=\"ult_exp_content \" style=\"background-color:rgba(219,88,167,0.06);  \"><div class=\"ult_ecpsub_cont\" style=\" \" >[vc_column_text css=&#8221;.vc_custom_1627661969836{margin-top: -20px !important;padding-right: 20px !important;padding-left: 20px !important;}&#8221;]<\/p>\n<p>&nbsp;<\/p>\n<p style=\"text-align: left;font-size: 18px\"><strong>Autoimmune Encephalitis (AE) Gene Expression Study<\/strong><\/p>\n<p style=\"text-align: left;font-size: 18px\">The goal of this study is to identify key molecular and cellular mechanisms of immune responses in childhood autoimmune encephalitides in order to help identify potential disease biomarkers and develop new targeted therapies. <a href=\"https:\/\/lab.research.sickkids.ca\/neuroinflamm\/research\/therapies-outcomes-in-autoimmune-encephalopathy\/\">Learn more here<\/a>.<\/p>\n<p style=\"text-align: left;font-size: 18px\">You may be eligible for this study as a <strong>healthy control participant<\/strong> if you:<\/p>\n<ul>\n<li style=\"font-size: 18px;text-align: left\">are under 18 years old;<\/li>\n<li style=\"font-size: 18px;text-align: left\">have no significant medical history.<\/li>\n<\/ul>\n<p style=\"text-align: left;font-size: 18px\">If interested in learning more, please contact <a href=\"mailto:yeh.team@sickkids.ca\">Carmen Yea<\/a> (416-813-7654 x 308828) or <a href=\"mailto:yeh.team@sickkids.ca\">Olivia Lau<\/a> (416-813-7654 x 328577).<\/p>\n<p>[\/vc_column_text]<\/div><\/div>\n\n\t\t\t<\/div><div class=\"ult_exp_section_layer ult-adjust-bottom-margin  \" >\n\t\t<div id=\"uvc-exp-wrap-2950\" role=\"button\" tabindex=\"0\" aria-pressed=\"false\"  data-ultimate-target='#uvc-exp-wrap-2950'  data-responsive-json-new='{\"font-size\":\"desktop:25px;\",\"line-height\":\"desktop:50px;\"}'  class=\"ult_exp_section  ult-responsive \" style=\"color:#0068b3;background-color:#eaf2fb;font-weight:bold;  text-align:center;\" data-textcolor=\"#0068b3\"data-texthover=\"#db58a7\"data-icncolor=\"#333333\"data-ihover=\"#333333\"data-height=\"0\"data-cntbg=\"#eaf2fb\"data-cnthvrbg=\"rgba(219,88,167,0.06)\"data-headerbg=\"#eaf2fb\"data-headerhover=\"rgba(219,88,167,0.06)\"data-title=\"OTHER STUDIES\"data-newtitle=\"OTHER STUDIES\"data-icon=\"\"data-newicon=\"\"data-activeicon=\"#333333\"data-effect=\"slideToggle\"data-override=\"0\"data-activetitle=\"#db58a7\"data-activebg=\"rgba(219,88,167,0.06)\"data-img=\"\"data-newimg=\"\"><div  class=\"ult_exp_section-main \">\n\t\t\t\t\t<div class=\"ult_expheader\" >OTHER STUDIES\n\t\t\t\t\t <\/div><\/div>\n\t\t\t\t<\/div><div class=\"ult_exp_content \" style=\"background-color:rgba(219,88,167,0.06);  \"><div class=\"ult_ecpsub_cont\" style=\" \" >[vc_column_text css=&#8221;.vc_custom_1627662136143{margin-top: -20px !important;padding-right: 20px !important;padding-left: 20px !important;}&#8221;]<\/p>\n<p style=\"font-size: 18px;text-align: center\">Check back later for new opportunities!<\/p>\n<p>[\/vc_column_text]<\/div><\/div>\n\n\t\t\t<\/div>\n\t\t\t            <\/div>\n        \t<\/dd>\n    \t<\/dl>\n    <!--<div class=\"extraborder\" style=\"background-color:#4f90d1\"><\/div>-->\n<\/div>\n\n<\/div>[\/vc_column][\/vc_row][vc_row][vc_column][vc_cta h2=&#8221;LEARN MORE ABOUT OUR RESEARCH&#8221; h2_font_container=&#8221;color:%23db58a7&#8243; h2_google_fonts=&#8221;font_family:Poiret%20One%3Aregular|font_style:400%20regular%3A400%3Anormal&#8221; txt_align=&#8221;center&#8221; shape=&#8221;round&#8221; style=&#8221;3d&#8221; use_custom_fonts_h2=&#8221;true&#8221; css=&#8221;.vc_custom_1627678166111{padding-top: 30px !important;padding-bottom: 30px !important;background-color: rgba(235,235,235,0.37) !important;*background-color: rgb(235,235,235) !important;}&#8221;]<\/p>\n<h4 style=\"text-align: center\">To learn more about what our research participants do,<br \/>\nvisit the <a style=\"color: #0068b3;text-decoration: underline\" href=\"https:\/\/lab.research.sickkids.ca\/neuroinflamm\/research\/research-components\/\" target=\"_blank\" rel=\"noopener\">Research Components<\/a> page.<\/h4>\n<p>&nbsp;<\/p>\n<h4 style=\"text-align: center\">To view our past publications, please <a style=\"color: #0068b3;text-decoration: underline\" href=\"https:\/\/lab.research.sickkids.ca\/neuroinflamm\/research\/publications\/\" target=\"_blank\" rel=\"noopener\">click here<\/a>.<\/h4>\n<p>[\/vc_cta][\/vc_column][\/vc_row][vc_row][vc_column][vc_row_inner disable_element=&#8221;yes&#8221;][vc_column_inner]<div class=\"ult_exp_section_layer ult-adjust-bottom-margin  \" >\n\t\t<div id=\"uvc-exp-wrap-6676\" role=\"button\" tabindex=\"0\" aria-pressed=\"false\"  data-ultimate-target='#uvc-exp-wrap-6676'  data-responsive-json-new='{\"font-size\":\"desktop:25px;\",\"line-height\":\"desktop:50px;\"}'  class=\"ult_exp_section  ult-responsive \" style=\"color:#0068b3;background-color:#eaf2fb;font-weight:bold;  text-align:center;\" data-textcolor=\"#0068b3\"data-texthover=\"#db58a7\"data-icncolor=\"#333333\"data-ihover=\"#333333\"data-height=\"0\"data-cntbg=\"#eaf2fb\"data-cnthvrbg=\"rgba(219,88,167,0.06)\"data-headerbg=\"#eaf2fb\"data-headerhover=\"rgba(219,88,167,0.06)\"data-title=\"LIFESTYLE OUTCOMES\"data-newtitle=\"LIFESTYLE OUTCOMES\"data-icon=\"\"data-newicon=\"\"data-activeicon=\"#333333\"data-effect=\"slideToggle\"data-override=\"0\"data-activetitle=\"#db58a7\"data-activebg=\"rgba(219,88,167,0.06)\"data-img=\"\"data-newimg=\"\"><div  class=\"ult_exp_section-main \">\n\t\t\t\t\t<div class=\"ult_expheader\" >LIFESTYLE OUTCOMES\n\t\t\t\t\t <\/div><\/div>\n\t\t\t\t<\/div><div class=\"ult_exp_content \" style=\"background-color:rgba(219,88,167,0.06);  \"><div class=\"ult_ecpsub_cont\" style=\" \" >[vc_column_text css=&#8221;.vc_custom_1627660342513{margin-top: -20px !important;padding-right: 20px !important;padding-left: 20px !important;}&#8221;]<\/p>\n<p style=\"text-align: left;font-size: 18px\"><strong>Metformin in Children and Young Adults with MS Study<\/strong><\/p>\n<p style=\"text-align: left;font-size: 18px\">We want to see if we can repair damaged myelin in children and young adults with MS using a drug called metformin. Previous research has shown that metformin helps repair myelin in mice and may be associated with decreased relapses in adults with MS and metabolic syndromes. <a href=\"https:\/\/lab.research.sickkids.ca\/neuroinflamm\/research\/visual-neurocognitive-outcomes\/\">Learn more here<\/a>.<\/p>\n<p style=\"text-align: left;font-size: 18px\">You may be eligible for this study if you:<\/p>\n<ul>\n<li style=\"font-size: 18px;text-align: left\">are between 10 and 26 years old;<\/li>\n<li style=\"font-size: 18px;text-align: left\">have been diagnosed with MS.<\/li>\n<\/ul>\n<p style=\"text-align: left;font-size: 18px\">If interested in learning more, please contact <a href=\"mailto:yeh.team@sickkids.ca\">Brenna Wong<\/a> (416-813-7654 x 415744).<\/p>\n<p>&nbsp;<\/p>\n<p style=\"text-align: left;font-size: 18px\"><strong>OMAS Study<\/strong><\/p>\n<p style=\"text-align: left;font-size: 18px\">The goal of this study is to investigate eye movement outcomes in relation to brain volume, cognitive function, and disease severity in pediatric OMAS. <a href=\"https:\/\/lab.research.sickkids.ca\/neuroinflamm\/research\/visual-neurocognitive-outcomes\/\">Learn more here<\/a>.<\/p>\n<p style=\"text-align: left;font-size: 18px\">You may be eligible for this study if you:<\/p>\n<ul>\n<li style=\"font-size: 18px;text-align: left\">are between 6 and 18 years old;<\/li>\n<li style=\"font-size: 18px;text-align: left\">have been diagnosed with OMAS.<\/li>\n<\/ul>\n<p style=\"text-align: left;font-size: 18px\">If interested in learning more, please contact <a href=\"mailto:yeh.team@sickkids.ca\">Tara Feltham<\/a>\u00a0(416-813-7654 x 328576).<\/p>\n<p>[\/vc_column_text]<\/div><\/div>\n\n\t\t\t<\/div><div class=\"ult_exp_section_layer ult-adjust-bottom-margin  \" >\n\t\t<div id=\"uvc-exp-wrap-3115\" role=\"button\" tabindex=\"0\" aria-pressed=\"false\"  data-ultimate-target='#uvc-exp-wrap-3115'  data-responsive-json-new='{\"font-size\":\"desktop:25px;\",\"line-height\":\"desktop:50px;\"}'  class=\"ult_exp_section  ult-responsive \" style=\"color:#0068b3;background-color:#eaf2fb;font-weight:bold;  text-align:center;\" data-textcolor=\"#0068b3\"data-texthover=\"#db58a7\"data-icncolor=\"#333333\"data-ihover=\"#333333\"data-height=\"0\"data-cntbg=\"#eaf2fb\"data-cnthvrbg=\"rgba(219,88,167,0.06)\"data-headerbg=\"#eaf2fb\"data-headerhover=\"rgba(219,88,167,0.06)\"data-title=\"THERAPIES &amp; OUTCOMES IN AUTOIMMUNE ENCEPHALOPATHY\"data-newtitle=\"THERAPIES &amp; OUTCOMES IN AUTOIMMUNE ENCEPHALOPATHY\"data-icon=\"\"data-newicon=\"\"data-activeicon=\"#333333\"data-effect=\"slideToggle\"data-override=\"0\"data-activetitle=\"#db58a7\"data-activebg=\"rgba(219,88,167,0.06)\"data-img=\"\"data-newimg=\"\"><div  class=\"ult_exp_section-main \">\n\t\t\t\t\t<div class=\"ult_expheader\" >THERAPIES &amp; OUTCOMES IN AUTOIMMUNE ENCEPHALOPATHY\n\t\t\t\t\t <\/div><\/div>\n\t\t\t\t<\/div><div class=\"ult_exp_content \" style=\"background-color:rgba(219,88,167,0.06);  \"><div class=\"ult_ecpsub_cont\" style=\" \" >[vc_column_text css=&#8221;.vc_custom_1627660372297{margin-top: -20px !important;padding-right: 20px !important;padding-left: 20px !important;}&#8221;]<\/p>\n<p style=\"text-align: left;font-size: 18px\"><strong>Autoimmune Encephalitis (AE) Gene Expression Study<\/strong><\/p>\n<p style=\"text-align: left;font-size: 18px\">The goal of this study is to identify key molecular and cellular mechanisms of immune responses in childhood autoimmune encephalitides in order to help identify potential disease biomarkers and develop new targeted therapies. <a href=\"https:\/\/lab.research.sickkids.ca\/neuroinflamm\/research\/therapies-outcomes-in-autoimmune-encephalopathy\/\">Learn more here<\/a>.<\/p>\n<p style=\"text-align: left;font-size: 18px\">You may be eligible for this study if you:<\/p>\n<ul>\n<li style=\"font-size: 18px;text-align: left\">are under 18 years old;<\/li>\n<li style=\"font-size: 18px;text-align: left\">have been diagnosed with autoimmune encephalitis.<\/li>\n<\/ul>\n<p style=\"text-align: left;font-size: 18px\">If interested in learning more, please contact <a href=\"mailto:yeh.team@sickkids.ca\">Carmen Yea<\/a> (416-813-7654 x 308828)<\/p>\n<p>[\/vc_column_text]<\/div><\/div>\n\n\t\t\t<\/div><div class=\"ult_exp_section_layer ult-adjust-bottom-margin  \" >\n\t\t<div id=\"uvc-exp-wrap-6448\" role=\"button\" tabindex=\"0\" aria-pressed=\"false\"  data-ultimate-target='#uvc-exp-wrap-6448'  data-responsive-json-new='{\"font-size\":\"desktop:25px;\",\"line-height\":\"desktop:50px;\"}'  class=\"ult_exp_section  ult-responsive \" style=\"color:#0068b3;background-color:#eaf2fb;font-weight:bold;  text-align:center;\" data-textcolor=\"#0068b3\"data-texthover=\"#db58a7\"data-icncolor=\"#333333\"data-ihover=\"#333333\"data-height=\"0\"data-cntbg=\"#eaf2fb\"data-cnthvrbg=\"rgba(219,88,167,0.06)\"data-headerbg=\"#eaf2fb\"data-headerhover=\"rgba(219,88,167,0.06)\"data-title=\"OTHER STUDIES\"data-newtitle=\"OTHER STUDIES\"data-icon=\"\"data-newicon=\"\"data-activeicon=\"#333333\"data-effect=\"slideToggle\"data-override=\"0\"data-activetitle=\"#db58a7\"data-activebg=\"rgba(219,88,167,0.06)\"data-img=\"\"data-newimg=\"\"><div  class=\"ult_exp_section-main \">\n\t\t\t\t\t<div class=\"ult_expheader\" >OTHER STUDIES\n\t\t\t\t\t <\/div><\/div>\n\t\t\t\t<\/div><div class=\"ult_exp_content \" style=\"background-color:rgba(219,88,167,0.06);  \"><div class=\"ult_ecpsub_cont\" style=\" \" >[vc_column_text css=&#8221;.vc_custom_1627660383628{margin-top: -20px !important;padding-right: 20px !important;padding-left: 20px !important;}&#8221;]<\/p>\n<p style=\"text-align: left;font-size: 18px\"><strong>Neuroinflammatory Patient Registry Study<\/strong><\/p>\n<p style=\"text-align: left;font-size: 18px\">The purpose of the Registry is to collect information on children with neuroinflammatory disorders for use in research aimed to increase our knowledge of childhood neuroinflammation and to help doctors develop better ways to diagnose and treat children with this rare condition. <a href=\"https:\/\/lab.research.sickkids.ca\/neuroinflamm\/research\/other-studies\/\">Learn more here<\/a>.<\/p>\n<p style=\"text-align: left;font-size: 18px\">You may be eligible for this study if you:<\/p>\n<ul>\n<li style=\"font-size: 18px;text-align: left\">are under 18 years old;<\/li>\n<li style=\"font-size: 18px;text-align: left\">have been diagnosed with a neuroinflammatory disorder or a suspected neuroinflammatory disorder.<\/li>\n<\/ul>\n<p>&nbsp;<\/p>\n<p style=\"text-align: left;font-size: 18px\"><strong>Acute Flaccid Paralysis (AFP) in Canadian Children Study<\/strong><\/p>\n<p style=\"text-align: left;font-size: 18px\">This study is a national collaborative retrospective evaluation of clinical and MRI outcomes of children presenting with non-polio acute onset flaccid paresis (AFP). <a href=\"https:\/\/lab.research.sickkids.ca\/neuroinflamm\/research\/other-studies\/\">Learn more here<\/a>.<\/p>\n<p style=\"text-align: left;font-size: 18px\">You may be eligible for this study if you:<\/p>\n<ul>\n<li style=\"font-size: 18px;text-align: left\">are under 18 years old;<\/li>\n<li style=\"font-size: 18px;text-align: left\">have been diagnosed with AFP in the past 30 days.<\/li>\n<\/ul>\n<p style=\"text-align: left;font-size: 18px\">If interested in learning more, please contact <a href=\"mailto:yeh.team@sickkids.ca\">Carmen Yea<\/a> (416-813-7654 x 308828).<\/p>\n<p>[\/vc_column_text]<\/div><\/div>\n\n\t\t\t<\/div>[vc_empty_space height=&#8221;15&#8243;]<form class=\"dt-contact-form dt-form privacy-form\" method=\"post\"><input type=\"hidden\" name=\"widget_id\" value=\"presscore-contact-form-widget--1\" \/><input type=\"hidden\" name=\"send_message\" value=\"\" \/><input type=\"hidden\" name=\"security_token\" value=\"7b7278327ad2d362127c\"\/><div class=\"form-fields\"><span class=\"form-name\"><label class=\"assistive-text\">Name *<\/label><input type=\"text\" class=\"validate[required]\" placeholder=\"Name *\" name=\"name\" value=\"\" aria-required=\"true\">\n<\/span><span class=\"form-mail\"><label class=\"assistive-text\">E-mail *<\/label><input type=\"text\" class=\"validate[required,custom[email]]\" placeholder=\"E-mail *\" name=\"email\" value=\"\" aria-required=\"true\">\n<\/span><span class=\"form-telephone\"><label class=\"assistive-text\">Telephone<\/label><input type=\"text\" placeholder=\"Telephone\" name=\"telephone\" value=\"\" aria-required=\"false\">\n<\/span><\/div><span class=\"form-message\"><label class=\"assistive-text\">Message<\/label><textarea placeholder=\"Message\" name=\"message\" rows=\"6\" aria-required=\"false\"><\/textarea>\n<\/span><p class=\"the7-form-terms-wrap\"><input type=\"checkbox\" id=\"the7-form-terms-7bcbf838aad2d6d4f975380ee45ef8d8\" name=\"terms\" class=\"validate[required] the7-form-terms\" aria-required=\"true\" \/>&nbsp;<label for=\"the7-form-terms-7bcbf838aad2d6d4f975380ee45ef8d8\"><span class=\"form-terms-text\">By using this form you agree with the storage and handling of your data by this website. Please <strong><span style=\"text-decoration: underline\">DO NOT<\/span><\/strong> use this contact form to send messages containing <strong>confidential<\/strong>, <strong>identifying<\/strong> or <strong>personal information<\/strong>.<\/span><\/label><\/p><p><a href=\"#\" class=\"dt-btn dt-btn-m dt-btn-submit\" rel=\"nofollow\"><span>SEND MESSAGE<\/span><\/a><input class=\"assistive-text\" type=\"submit\" value=\"submit\"><\/p><\/form>\n\n<div class=\"wpcf7 no-js\" id=\"wpcf7-f4-o1\" lang=\"en-US\" dir=\"ltr\" data-wpcf7-id=\"4\">\n<div class=\"screen-reader-response\"><p role=\"status\" aria-live=\"polite\" aria-atomic=\"true\"><\/p> <ul><\/ul><\/div>\n<form action=\"\/neuroinflamm\/wp-json\/wp\/v2\/pages\/263#wpcf7-f4-o1\" method=\"post\" class=\"wpcf7-form init\" aria-label=\"Contact form\" novalidate=\"novalidate\" data-status=\"init\">\n<fieldset class=\"hidden-fields-container\"><input type=\"hidden\" name=\"_wpcf7\" value=\"4\" \/><input type=\"hidden\" name=\"_wpcf7_version\" value=\"6.1.5\" \/><input type=\"hidden\" name=\"_wpcf7_locale\" value=\"en_US\" \/><input type=\"hidden\" name=\"_wpcf7_unit_tag\" value=\"wpcf7-f4-o1\" \/><input type=\"hidden\" name=\"_wpcf7_container_post\" value=\"0\" \/><input type=\"hidden\" name=\"_wpcf7_posted_data_hash\" value=\"\" \/>\n<\/fieldset>\n<p><script type=\"text\/javascript\">\nfunction toggle(source) {\n checkboxes = document.getElementsByName('foo');\n for(var i=0, n=checkboxes.length;i\n<\/script>\n<\/p>\n<h1 style=\"padding-top: 40px; color: #0068b3; font-size: 25px; font-weight: bolder; text-align: left;\">INTERESTED IN VOLUNTEERING WITH OUR RESEARCH STUDIES?\n<\/h1>\n<p style=\"text-align: left; color: #767a83; font-size: 17px; line-height: 20px; font-family: 'Roboto Condensed'; font-weight: 400;\">We welcome both <strong>patients<\/strong> and <strong>healthy volunteers<\/strong> to take part in the studies that our team is currently recruiting for.\n<\/p>\n<p style=\"text-align: left; color: #767a83; font-size: 17px; line-height: 20px; font-family: 'Roboto Condensed'; font-weight: 400;\">To learn more about how to take part in our research studies please email us at <a style=\"color: #0068b3; text-decoration: underline;\" href=\"mailto:yeh.team@sickkids.ca\">yeh.team@sickkids.ca<\/a> or submit the form below.\n<\/p>\n<p><span class=\"wpcf7-form-control-wrap\" data-name=\"your-name\"><input size=\"40\" maxlength=\"400\" class=\"wpcf7-form-control wpcf7-text wpcf7-validates-as-required contact_form\" id=\"form_name\" aria-required=\"true\" aria-invalid=\"false\" placeholder=\"Your Name (Required)\" value=\"\" type=\"text\" name=\"your-name\" \/><\/span>\n<\/p>\n<p><span class=\"wpcf7-form-control-wrap\" data-name=\"your-email\"><input size=\"40\" maxlength=\"400\" class=\"wpcf7-form-control wpcf7-email wpcf7-validates-as-required wpcf7-text wpcf7-validates-as-email contact_form\" id=\"form_email\" aria-required=\"true\" aria-invalid=\"false\" placeholder=\"Your Email (Required)\" value=\"\" type=\"email\" name=\"your-email\" \/><\/span>\n<\/p>\n<p><span class=\"wpcf7-form-control-wrap\" data-name=\"your-number\"><input size=\"40\" maxlength=\"400\" class=\"wpcf7-form-control wpcf7-tel wpcf7-text wpcf7-validates-as-tel contact_form\" id=\"form_number\" aria-invalid=\"false\" placeholder=\"Your Phone Number (Optional)\" value=\"\" type=\"tel\" name=\"your-number\" \/><\/span>\n<\/p>\n<p>Type of Participant (optional)\n<\/p>\n<p><span class=\"wpcf7-form-control-wrap\" data-name=\"participant-type\"><select class=\"wpcf7-form-control wpcf7-select contact_form\" id=\"form_participant\" aria-invalid=\"false\" name=\"participant-type\"><option value=\"\">&#8212;Please choose an option&#8212;<\/option><option value=\"Patient\">Patient<\/option><option value=\"Healthy Control\">Healthy Control<\/option><\/select><\/span>\n<\/p>\n<p>Studies of Interest (optional)<br \/>\n<span style=\"font-size: 12px;\">*Hold the control key down while clicking to select multiple studies.<\/span><br \/>\n<span class=\"wpcf7-form-control-wrap\" data-name=\"your-sel\"><select class=\"wpcf7-form-control wpcf7-select contact_form\" id=\"form_study\" aria-invalid=\"false\" multiple=\"multiple\" name=\"your-sel[]\"><option value=\"Neuroinflammatory Patient Registry Study\">Neuroinflammatory Patient Registry Study<\/option><option value=\"Social Networks Study\">Social Networks Study<\/option><option value=\"ATOMIC Physical Activity Study\">ATOMIC Physical Activity Study<\/option><option value=\"Autoimmune Encephalitis (AE) Gene Expression Study\">Autoimmune Encephalitis (AE) Gene Expression Study<\/option><option value=\"Acute Flaccid Paralysis (AFP) in Canadian Children Study\">Acute Flaccid Paralysis (AFP) in Canadian Children Study<\/option><option value=\"Metformin in Children with MS Study\">Metformin in Children with MS Study<\/option><option value=\"OMAS Study\">OMAS Study<\/option><\/select><\/span>\n<\/p>\n<p><span class=\"wpcf7-form-control-wrap\" data-name=\"your-message\"><textarea cols=\"40\" rows=\"10\" maxlength=\"2000\" class=\"wpcf7-form-control wpcf7-textarea wpcf7-validates-as-required contact_form\" id=\"form_message\" aria-required=\"true\" aria-invalid=\"false\" placeholder=\"Your Message (Required)\" name=\"your-message\"><\/textarea><\/span>\n<\/p>\n<p>By using this form you agree with the storage and handling of your data by this website. Please <strong><span style=\"text-decoration: underline;\">DO NOT<\/span><\/strong> use this contact form to send messages containing <strong>confidential<\/strong>, <strong>identifying<\/strong> or <strong>personal information<\/strong>.\n<\/p>\n<p><input class=\"wpcf7-form-control wpcf7-submit has-spinner\" type=\"submit\" value=\"SEND MESSAGE\" \/>\n<\/p><div class=\"wpcf7-response-output\" aria-hidden=\"true\"><\/div>\n<\/form>\n<\/div>\n[vc_column_text]<\/p>\n<h1 style=\"color: #0068b3;font-size: 25px;font-weight: bolder;text-align: left\">INTERESTED IN VOLUNTEERING WITH OUR RESEARCH STUDIES?<\/h1>\n<p style=\"text-align: left;color: #767a83;font-size: 17px;line-height: 20px;font-family: 'Roboto Condensed';font-weight: 400\">We welcome both <strong>patients<\/strong> and <strong>healthy volunteers<\/strong> to take part in the studies that our team is currently recruiting for.<\/p>\n<p style=\"text-align: left;color: #767a83;font-size: 17px;line-height: 20px;font-family: 'Roboto Condensed';font-weight: 550\">To learn more about how to take part in our research studies please email us at <a style=\"color: #0068b3;text-decoration: underline\" href=\"mailto:yeh.team@sickkids.ca\">yeh.team@sickkids.ca<\/a> or submit the form below.<\/p>\n<p>[\/vc_column_text][\/vc_column_inner][\/vc_row_inner][\/vc_column][\/vc_row][vc_row][vc_column][vc_row_inner][vc_column_inner][\/vc_column_inner][\/vc_row_inner][\/vc_column][\/vc_row]<\/p>\n<\/div>","protected":false},"excerpt":{"rendered":"<p>[vc_row][vc_column][vc_empty_space height=&#8221;60px&#8221;][vc_empty_space height=&#8221;10&#8243;][\/vc_column][\/vc_row][vc_row][vc_column][\/vc_column][\/vc_row][vc_row][vc_column][vc_cta h2=&#8221;LEARN MORE ABOUT OUR RESEARCH&#8221; h2_font_container=&#8221;color:%23db58a7&#8243; h2_google_fonts=&#8221;font_family:Poiret%20One%3Aregular|font_style:400%20regular%3A400%3Anormal&#8221; txt_align=&#8221;center&#8221; shape=&#8221;round&#8221; style=&#8221;3d&#8221; use_custom_fonts_h2=&#8221;true&#8221; css=&#8221;.vc_custom_1627678166111{padding-top: 30px !important;padding-bottom: 30px !important;background-color: rgba(235,235,235,0.37) !important;*background-color: rgb(235,235,235) !important;}&#8221;] To learn more about what our research participants do, visit the Research Components page. &nbsp; To view our past publications, please click here. [\/vc_cta][\/vc_column][\/vc_row][vc_row][vc_column][vc_row_inner disable_element=&#8221;yes&#8221;][vc_column_inner][vc_empty_space height=&#8221;15&#8243;][vc_column_text] INTERESTED IN VOLUNTEERING WITH OUR RESEARCH&hellip;<\/p>\n","protected":false},"author":119,"featured_media":0,"parent":0,"menu_order":0,"comment_status":"closed","ping_status":"closed","template":"","meta":{"footnotes":""},"class_list":["post-263","page","type-page","status-publish","hentry","description-off"],"yoast_head":"<!-- This site is optimized with the Yoast SEO Premium plugin v27.0 (Yoast SEO v27.0) - https:\/\/yoast.com\/product\/yoast-seo-premium-wordpress\/ -->\n<title>Research - Paediatric Neuroinflammatory Disorders Program<\/title>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/lab.research.sickkids.ca\/neuroinflamm\/research\/\" \/>\n<meta property=\"og:locale\" content=\"en_US\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"Research\" \/>\n<meta property=\"og:description\" content=\"[vc_row][vc_column][vc_empty_space height=&#8221;60px&#8221;][vc_empty_space height=&#8221;10&#8243;][\/vc_column][\/vc_row][vc_row][vc_column][\/vc_column][\/vc_row][vc_row][vc_column][vc_cta h2=&#8221;LEARN MORE ABOUT OUR RESEARCH&#8221; h2_font_container=&#8221;color:%23db58a7&#8243; h2_google_fonts=&#8221;font_family:Poiret%20One%3Aregular|font_style:400%20regular%3A400%3Anormal&#8221; txt_align=&#8221;center&#8221; shape=&#8221;round&#8221; style=&#8221;3d&#8221; use_custom_fonts_h2=&#8221;true&#8221; css=&#8221;.vc_custom_1627678166111{padding-top: 30px !important;padding-bottom: 30px !important;background-color: rgba(235,235,235,0.37) !important;*background-color: rgb(235,235,235) !important;}&#8221;] To learn more about what our research participants do, visit the Research Components page. &nbsp; To view our past publications, please click here. [\/vc_cta][\/vc_column][\/vc_row][vc_row][vc_column][vc_row_inner disable_element=&#8221;yes&#8221;][vc_column_inner][vc_empty_space height=&#8221;15&#8243;][vc_column_text] INTERESTED IN VOLUNTEERING WITH OUR RESEARCH&hellip;\" \/>\n<meta property=\"og:url\" content=\"https:\/\/lab.research.sickkids.ca\/neuroinflamm\/research\/\" \/>\n<meta property=\"og:site_name\" content=\"Paediatric Neuroinflammatory Disorders Program\" \/>\n<meta property=\"article:modified_time\" content=\"2025-05-08T15:42:34+00:00\" \/>\n<meta name=\"twitter:card\" content=\"summary_large_image\" \/>\n<meta name=\"twitter:label1\" content=\"Est. reading time\" \/>\n\t<meta name=\"twitter:data1\" content=\"12 minutes\" \/>\n<script type=\"application\/ld+json\" class=\"yoast-schema-graph\">{\"@context\":\"https:\/\/schema.org\",\"@graph\":[{\"@type\":\"WebPage\",\"@id\":\"https:\/\/lab.research.sickkids.ca\/neuroinflamm\/research\/\",\"url\":\"https:\/\/lab.research.sickkids.ca\/neuroinflamm\/research\/\",\"name\":\"Research - Paediatric Neuroinflammatory Disorders Program\",\"isPartOf\":{\"@id\":\"https:\/\/lab.research.sickkids.ca\/neuroinflamm\/#website\"},\"datePublished\":\"2017-09-22T20:05:08+00:00\",\"dateModified\":\"2025-05-08T15:42:34+00:00\",\"breadcrumb\":{\"@id\":\"https:\/\/lab.research.sickkids.ca\/neuroinflamm\/research\/#breadcrumb\"},\"inLanguage\":\"en-CA\",\"potentialAction\":[{\"@type\":\"ReadAction\",\"target\":[\"https:\/\/lab.research.sickkids.ca\/neuroinflamm\/research\/\"]}]},{\"@type\":\"BreadcrumbList\",\"@id\":\"https:\/\/lab.research.sickkids.ca\/neuroinflamm\/research\/#breadcrumb\",\"itemListElement\":[{\"@type\":\"ListItem\",\"position\":1,\"name\":\"Home\",\"item\":\"https:\/\/lab.research.sickkids.ca\/neuroinflamm\/\"},{\"@type\":\"ListItem\",\"position\":2,\"name\":\"Research\"}]},{\"@type\":\"WebSite\",\"@id\":\"https:\/\/lab.research.sickkids.ca\/neuroinflamm\/#website\",\"url\":\"https:\/\/lab.research.sickkids.ca\/neuroinflamm\/\",\"name\":\"Paediatric Neuroinflammatory Disorders Program\",\"description\":\"Paediatric Neuroinflammatory Disorders Program\",\"potentialAction\":[{\"@type\":\"SearchAction\",\"target\":{\"@type\":\"EntryPoint\",\"urlTemplate\":\"https:\/\/lab.research.sickkids.ca\/neuroinflamm\/?s={search_term_string}\"},\"query-input\":{\"@type\":\"PropertyValueSpecification\",\"valueRequired\":true,\"valueName\":\"search_term_string\"}}],\"inLanguage\":\"en-CA\"}]}<\/script>\n<!-- \/ Yoast SEO Premium plugin. -->","yoast_head_json":{"title":"Research - Paediatric Neuroinflammatory Disorders Program","robots":{"index":"index","follow":"follow","max-snippet":"max-snippet:-1","max-image-preview":"max-image-preview:large","max-video-preview":"max-video-preview:-1"},"canonical":"https:\/\/lab.research.sickkids.ca\/neuroinflamm\/research\/","og_locale":"en_US","og_type":"article","og_title":"Research","og_description":"[vc_row][vc_column][vc_empty_space height=&#8221;60px&#8221;][vc_empty_space height=&#8221;10&#8243;][\/vc_column][\/vc_row][vc_row][vc_column][\/vc_column][\/vc_row][vc_row][vc_column][vc_cta h2=&#8221;LEARN MORE ABOUT OUR RESEARCH&#8221; h2_font_container=&#8221;color:%23db58a7&#8243; h2_google_fonts=&#8221;font_family:Poiret%20One%3Aregular|font_style:400%20regular%3A400%3Anormal&#8221; txt_align=&#8221;center&#8221; shape=&#8221;round&#8221; style=&#8221;3d&#8221; use_custom_fonts_h2=&#8221;true&#8221; css=&#8221;.vc_custom_1627678166111{padding-top: 30px !important;padding-bottom: 30px !important;background-color: rgba(235,235,235,0.37) !important;*background-color: rgb(235,235,235) !important;}&#8221;] To learn more about what our research participants do, visit the Research Components page. &nbsp; To view our past publications, please click here. 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