The High-Resolution High-Throughput CryoEM core is used for high-resolution structure determination of proteins that have already been screened at other facilities. <\/p>\n
The facility provides state-of-the-art high-resolution imaging that can extend resolution from 4 to 6 \u00c5 to 2 to 4 \u00c5. It does not provide an advantage for obtaining structures at less than 4 \u00c5 resolution, and it is not suitable for screening samples.<\/p>\n
We facilitate high-resolution and high-throughput data collection for single particle electron cryomicroscopy of proteins and protein complexes. These data are collected with the ultimate goal of determining three-dimensional structures of protein and contributing to the development of drugs.<\/p>\n<\/div><\/div><\/div><\/div><\/div>
High-resolution high-throughput CryoEM<\/span><\/p>\n<\/div>The High-Resolution High-Throughput CryoEM core is used for high-resolution structure determination of proteins that have already been screened at other facilities. <\/span><\/p>\nThe facility provides state-of-the-art high-resolution imaging that can extend resolution from 4 to 6 \u00c5 to 2 to 4 \u00c5. It does not provide an advantage for obtaining structures at less than 4 \u00c5 resolution, and it is not suitable for screening samples.<\/span><\/p>\nWe house high-end microscopes with high-resolution and high-throughput data using cryo-electron microscopy single particle analysis, with the ultimate goal of producing three-dimensional structures of proteins to understand their function, and contribute to developing drugs that interact with it.<\/span><\/p>\n<\/div><\/div><\/div><\/div><\/div>