{"id":7,"date":"2019-04-11T13:21:04","date_gmt":"2019-04-11T13:21:04","guid":{"rendered":"https:\/\/lab.research.sickkids.ca\/maass\/?page_id=7"},"modified":"2023-01-31T20:27:20","modified_gmt":"2023-01-31T20:27:20","slug":"home","status":"publish","type":"page","link":"https:\/\/lab.research.sickkids.ca\/maass\/","title":{"rendered":"Home"},"content":{"rendered":"<div class=\"wpb-content-wrapper\"><p>[vc_row][vc_column width=&#8221;1\/2&#8243;][vc_column_text css_animation=&#8221;fadeIn&#8221;]<\/p>\n<h5>Our central objective is to gain mechanistic insight into the regulatory functions of the non-coding genome. We use an interdisciplinary systems biology approach of genome biology, live-cell imaging (biophysics), biochemistry, and translational research to address the following questions:<\/h5>\n<p>[\/vc_column_text][vc_column_text css_animation=&#8221;fadeIn&#8221;]<\/p>\n<ul>\n<li>\n<h5><strong>How are chromosomal territories organized?<\/strong><\/h5>\n<\/li>\n<li>\n<h5><strong>How do <em>inter<\/em>-chromosomal contacts facilitate gene regulation and genome organization?<\/strong><\/h5>\n<\/li>\n<li>\n<h5><strong>How do non-coding RNA genes function?<\/strong><\/h5>\n<\/li>\n<li>\n<h5><strong>How are functional elements of the non-coding genome involved in pathogenesis?<\/strong><\/h5>\n<\/li>\n<\/ul>\n<p>[\/vc_column_text][\/vc_column][vc_column width=&#8221;1\/2&#8243;][vc_single_image image=&#8221;89&#8243; img_size=&#8221;full&#8221; style=&#8221;vc_box_shadow&#8221; onclick=&#8221;link_image&#8221; css_animation=&#8221;fadeIn&#8221;][\/vc_column][\/vc_row][vc_row][vc_column width=&#8221;1\/6&#8243;][\/vc_column][vc_column width=&#8221;2\/3&#8243;][\/vc_column][vc_column width=&#8221;1\/6&#8243;][\/vc_column][\/vc_row]<\/p>\n<\/div>","protected":false},"excerpt":{"rendered":"<p>[vc_row][vc_column width=&#8221;1\/2&#8243;][vc_column_text css_animation=&#8221;fadeIn&#8221;] Our central objective is to gain mechanistic insight into the regulatory functions of the non-coding genome. We use an interdisciplinary systems biology approach of genome biology, live-cell imaging (biophysics), biochemistry, and translational research to address the following questions: [\/vc_column_text][vc_column_text css_animation=&#8221;fadeIn&#8221;] How are chromosomal territories organized? How do inter-chromosomal contacts facilitate gene regulation&hellip;<\/p>\n","protected":false},"author":2,"featured_media":0,"parent":0,"menu_order":0,"comment_status":"closed","ping_status":"closed","template":"","meta":{"footnotes":""},"class_list":["post-7","page","type-page","status-publish","hentry","description-off"],"yoast_head":"<!-- This site is optimized with the Yoast SEO Premium plugin v27.0 (Yoast SEO v27.0) - https:\/\/yoast.com\/product\/yoast-seo-premium-wordpress\/ -->\n<title>Home - Maass Lab<\/title>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/lab.research.sickkids.ca\/maass\/\" \/>\n<meta property=\"og:locale\" content=\"en_US\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"Home\" \/>\n<meta property=\"og:description\" content=\"[vc_row][vc_column width=&#8221;1\/2&#8243;][vc_column_text css_animation=&#8221;fadeIn&#8221;] Our central objective is to gain mechanistic insight into the regulatory functions of the non-coding genome. 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