{"id":17,"date":"2015-10-10T19:31:34","date_gmt":"2015-10-10T19:31:34","guid":{"rendered":"https:\/\/lab.research.sickkids.ca\/julien\/?page_id=17"},"modified":"2026-02-01T14:50:37","modified_gmt":"2026-02-01T14:50:37","slug":"publications","status":"publish","type":"page","link":"https:\/\/lab.research.sickkids.ca\/julien\/publications\/","title":{"rendered":"Publications"},"content":{"rendered":"<div class=\"fusion-fullwidth fullwidth-box fusion-builder-row-1 hundred-percent-fullwidth non-hundred-percent-height-scrolling\" style=\"--awb-border-radius-top-left:0px;--awb-border-radius-top-right:0px;--awb-border-radius-bottom-right:0px;--awb-border-radius-bottom-left:0px;--awb-overflow:visible;--awb-flex-wrap:wrap;\" ><div class=\"fusion-builder-row fusion-row\"><div class=\"fusion-layout-column fusion_builder_column fusion-builder-column-0 fusion_builder_column_1_1 1_1 fusion-one-full fusion-column-first fusion-column-last\" style=\"--awb-bg-size:cover;\"><div class=\"fusion-column-wrapper fusion-flex-column-wrapper-legacy\"><div class=\"fusion-clearfix\"><\/div><\/div><\/div><div class=\"fusion-layout-column fusion_builder_column fusion-builder-column-1 fusion_builder_column_1_1 1_1 fusion-one-full fusion-column-first fusion-column-last\" style=\"--awb-bg-size:cover;\"><div class=\"fusion-column-wrapper fusion-flex-column-wrapper-legacy\"><div class=\"fusion-tabs fusion-tabs-1 classic vertical-tabs icon-position-left mobile-mode-accordion\" style=\"--awb-title-border-radius-top-left:0px;--awb-title-border-radius-top-right:0px;--awb-title-border-radius-bottom-right:0px;--awb-title-border-radius-bottom-left:0px;--awb-alignment:start;--awb-inactive-color:#ebeaea;--awb-background-color:#ffffff;--awb-border-color:#ebeaea;--awb-active-border-color:#1a80b6;\"><div class=\"nav\"><ul class=\"nav-tabs\" role=\"tablist\"><li class=\"active\" role=\"presentation\"><a class=\"tab-link\" data-toggle=\"tab\" role=\"tab\" aria-controls=\"tab-9d70e0de5f2fb055df5\" aria-selected=\"true\" id=\"fusion-tab-2026\" href=\"#tab-9d70e0de5f2fb055df5\"><h4 class=\"fusion-tab-heading\">2026<\/h4><\/a><\/li><li role=\"presentation\"><a class=\"tab-link\" data-toggle=\"tab\" role=\"tab\" aria-controls=\"tab-3f61b6978270da28efc\" aria-selected=\"false\" tabindex=\"-1\" id=\"fusion-tab-2025\" href=\"#tab-3f61b6978270da28efc\"><h4 class=\"fusion-tab-heading\">2025<\/h4><\/a><\/li><li role=\"presentation\"><a class=\"tab-link\" data-toggle=\"tab\" role=\"tab\" aria-controls=\"tab-bbdb76af9e88bd2f8b9\" aria-selected=\"false\" tabindex=\"-1\" id=\"fusion-tab-2024\" href=\"#tab-bbdb76af9e88bd2f8b9\"><h4 class=\"fusion-tab-heading\">2024<\/h4><\/a><\/li><li role=\"presentation\"><a class=\"tab-link\" data-toggle=\"tab\" role=\"tab\" aria-controls=\"tab-bdcb7e7a953a85891f7\" aria-selected=\"false\" tabindex=\"-1\" id=\"fusion-tab-2023\" href=\"#tab-bdcb7e7a953a85891f7\"><h4 class=\"fusion-tab-heading\">2023<\/h4><\/a><\/li><li role=\"presentation\"><a class=\"tab-link\" data-toggle=\"tab\" role=\"tab\" aria-controls=\"tab-73d22cc73f8b38ea1ef\" aria-selected=\"false\" tabindex=\"-1\" id=\"fusion-tab-2022\" href=\"#tab-73d22cc73f8b38ea1ef\"><h4 class=\"fusion-tab-heading\">2022<\/h4><\/a><\/li><li role=\"presentation\"><a class=\"tab-link\" data-toggle=\"tab\" role=\"tab\" aria-controls=\"tab-267e99459c826365c6c\" aria-selected=\"false\" tabindex=\"-1\" id=\"fusion-tab-2021\" href=\"#tab-267e99459c826365c6c\"><h4 class=\"fusion-tab-heading\">2021<\/h4><\/a><\/li><li role=\"presentation\"><a class=\"tab-link\" data-toggle=\"tab\" role=\"tab\" aria-controls=\"tab-5428f3f4b06bb488336\" aria-selected=\"false\" tabindex=\"-1\" id=\"fusion-tab-2020\" href=\"#tab-5428f3f4b06bb488336\"><h4 class=\"fusion-tab-heading\">2020<\/h4><\/a><\/li><li role=\"presentation\"><a class=\"tab-link\" data-toggle=\"tab\" role=\"tab\" aria-controls=\"tab-5d37cc70d17531dc115\" aria-selected=\"false\" tabindex=\"-1\" id=\"fusion-tab-2019\" href=\"#tab-5d37cc70d17531dc115\"><h4 class=\"fusion-tab-heading\">2019<\/h4><\/a><\/li><li role=\"presentation\"><a class=\"tab-link\" data-toggle=\"tab\" role=\"tab\" aria-controls=\"tab-3f37d601f7c349aee65\" aria-selected=\"false\" tabindex=\"-1\" id=\"fusion-tab-2018\" href=\"#tab-3f37d601f7c349aee65\"><h4 class=\"fusion-tab-heading\">2018<\/h4><\/a><\/li><li role=\"presentation\"><a class=\"tab-link\" data-toggle=\"tab\" role=\"tab\" aria-controls=\"tab-9786dee369dd6af6724\" aria-selected=\"false\" tabindex=\"-1\" id=\"fusion-tab-2017\" href=\"#tab-9786dee369dd6af6724\"><h4 class=\"fusion-tab-heading\">2017<\/h4><\/a><\/li><li role=\"presentation\"><a class=\"tab-link\" data-toggle=\"tab\" role=\"tab\" aria-controls=\"tab-ffd7a97064bd3c2206d\" aria-selected=\"false\" tabindex=\"-1\" id=\"fusion-tab-2016\" href=\"#tab-ffd7a97064bd3c2206d\"><h4 class=\"fusion-tab-heading\">2016<\/h4><\/a><\/li><li role=\"presentation\"><a class=\"tab-link\" data-toggle=\"tab\" role=\"tab\" aria-controls=\"tab-b499ed44594057c66a0\" aria-selected=\"false\" tabindex=\"-1\" id=\"fusion-tab-2015\" href=\"#tab-b499ed44594057c66a0\"><h4 class=\"fusion-tab-heading\">2015<\/h4><\/a><\/li><li role=\"presentation\"><a class=\"tab-link\" data-toggle=\"tab\" role=\"tab\" aria-controls=\"tab-835873251a38f2b70c8\" aria-selected=\"false\" tabindex=\"-1\" id=\"fusion-tab-2014\" href=\"#tab-835873251a38f2b70c8\"><h4 class=\"fusion-tab-heading\">2014<\/h4><\/a><\/li><li role=\"presentation\"><a class=\"tab-link\" data-toggle=\"tab\" role=\"tab\" aria-controls=\"tab-e00d04916de5f6293f2\" aria-selected=\"false\" tabindex=\"-1\" id=\"fusion-tab-2013\" href=\"#tab-e00d04916de5f6293f2\"><h4 class=\"fusion-tab-heading\">2013<\/h4><\/a><\/li><li role=\"presentation\"><a class=\"tab-link\" data-toggle=\"tab\" role=\"tab\" aria-controls=\"tab-047d121a944f94414b2\" aria-selected=\"false\" tabindex=\"-1\" id=\"fusion-tab-2012\" href=\"#tab-047d121a944f94414b2\"><h4 class=\"fusion-tab-heading\">2012<\/h4><\/a><\/li><li role=\"presentation\"><a class=\"tab-link\" data-toggle=\"tab\" role=\"tab\" aria-controls=\"tab-86acae89c9cc02b38c5\" aria-selected=\"false\" tabindex=\"-1\" id=\"fusion-tab-2011\" href=\"#tab-86acae89c9cc02b38c5\"><h4 class=\"fusion-tab-heading\">2011<\/h4><\/a><\/li><li role=\"presentation\"><a class=\"tab-link\" data-toggle=\"tab\" role=\"tab\" aria-controls=\"tab-cac579999c4eefd178a\" aria-selected=\"false\" tabindex=\"-1\" id=\"fusion-tab-2010\" href=\"#tab-cac579999c4eefd178a\"><h4 class=\"fusion-tab-heading\">2010<\/h4><\/a><\/li><li role=\"presentation\"><a class=\"tab-link\" data-toggle=\"tab\" role=\"tab\" aria-controls=\"tab-47581cc8595ecdb1fd1\" aria-selected=\"false\" tabindex=\"-1\" id=\"fusion-tab-2009\" href=\"#tab-47581cc8595ecdb1fd1\"><h4 class=\"fusion-tab-heading\">2009<\/h4><\/a><\/li><li role=\"presentation\"><a class=\"tab-link\" data-toggle=\"tab\" role=\"tab\" aria-controls=\"tab-523b2dcbe2155e07ab5\" aria-selected=\"false\" tabindex=\"-1\" id=\"fusion-tab-2008\" href=\"#tab-523b2dcbe2155e07ab5\"><h4 class=\"fusion-tab-heading\">2008<\/h4><\/a><\/li><li role=\"presentation\"><a class=\"tab-link\" data-toggle=\"tab\" role=\"tab\" aria-controls=\"tab-5afda7eccd42c3defe3\" aria-selected=\"false\" tabindex=\"-1\" id=\"fusion-tab-2006\" href=\"#tab-5afda7eccd42c3defe3\"><h4 class=\"fusion-tab-heading\">2006<\/h4><\/a><\/li><\/ul><\/div><div class=\"tab-content\"><div class=\"nav fusion-mobile-tab-nav\"><ul class=\"nav-tabs\" role=\"tablist\"><li class=\"active\" role=\"presentation\"><a class=\"tab-link\" data-toggle=\"tab\" role=\"tab\" aria-controls=\"tab-9d70e0de5f2fb055df5\" aria-selected=\"true\" id=\"mobile-fusion-tab-2026\" href=\"#tab-9d70e0de5f2fb055df5\"><h4 class=\"fusion-tab-heading\">2026<\/h4><\/a><\/li><\/ul><\/div><div class=\"tab-pane fade fusion-clearfix in active\" role=\"tabpanel\" tabindex=\"0\" aria-labelledby=\"fusion-tab-2026\" id=\"tab-9d70e0de5f2fb055df5\">\n<p class=\"title\"><a style=\"color: #000080\" href=\"https:\/\/www.nature.com\/articles\/s41467-026-68761-1\">A stabilized tandem antigen chimera that elicits potent malaria transmission-reducing activity.<\/a><\/p>\n<p>Ivanochko D, Miura K, Hailemariam S, Ravichandran R, Song Y, Huang WC, Stoter R, Teelen K, van Gemert GJ, Leaf EM, Chan S, Men C, Semesi A, Shiu C, MacGill RS, Long CA, Jore MM, King NP, Lovell JF, Julien JP.<\/p>\n<p><em>Nature Communications. 2026 Jan 24. doi: 10.1038\/s41467-026-68761-1.<\/em><\/p>\n<p class=\"title\"><a style=\"color: #000080\" href=\"https:\/\/www.biorxiv.org\/content\/10.64898\/2026.01.16.699998v1\">B Lymphocyte Protein Factories produced by Hematopoietic Stem Cell Gene Editing.<\/a><\/p>\n<p>Hartweger H, Ruprecht C, Yao KH, Laffont P, Lima Dos Reis G, Zhou P, H\u00e4ggl\u00f6f T, Binet L, Loewe M, Hong JP, Xiao T, Sefik E, Hernandez B, Gazumyan A, Jankovic M, Seaman MS, Costa G, Nelson SA, Clark J, Kanatani S, Wilson PC, Krammer F, Levashina EA, Julien JP, Wardemann H, Sinnis P, Stamatatos L, Flavell RA, Nussenzweig MC.<\/p>\n<p><em>bioRxiv. 2026 Jan 18. doi: 10.64898\/2026.01.16.699998.<\/em><\/p>\n<\/div><div class=\"nav fusion-mobile-tab-nav\"><ul class=\"nav-tabs\" role=\"tablist\"><li role=\"presentation\"><a class=\"tab-link\" data-toggle=\"tab\" role=\"tab\" aria-controls=\"tab-3f61b6978270da28efc\" aria-selected=\"false\" tabindex=\"-1\" id=\"mobile-fusion-tab-2025\" href=\"#tab-3f61b6978270da28efc\"><h4 class=\"fusion-tab-heading\">2025<\/h4><\/a><\/li><\/ul><\/div><div class=\"tab-pane fade fusion-clearfix\" role=\"tabpanel\" tabindex=\"0\" aria-labelledby=\"fusion-tab-2025\" id=\"tab-3f61b6978270da28efc\">\n<p class=\"title\"><a style=\"color: #000080\" href=\"https:\/\/journals.asm.org\/doi\/10.1128\/jvi.01523-25\">Human antibody targeting of coronavirus spike S2 subunit is associated with protection mediated by Fc effector functions.<\/a><\/p>\n<p>Muthuraman K, Jackman M, Liang Y, Garrett ME, Cui H, Vu Hong Nguyen L, Ivanochko D, Ye C, Pino PA, Hicks A, Maingot B, Yusko E, Benzeno S, Mart\u00ednez-Sobrido L, Torrelles JB, Gilbert AE, Rubin BER, Keitany G, Jetha A, Julien JP.<\/p>\n<p><em>Journal of Virology. 2025 Nov 12. 99(12):e0152325. doi: 10.1128\/jvi.01523-25.<\/em><\/p>\n<p class=\"title\"><a style=\"color: #000080\" href=\"https:\/\/pubs.acs.org\/doi\/full\/10.1021\/jacsau.5c01013\">Molecular Insights into the Engagement of High-Affinity Sialylated Ligands to Human CD22.<\/a><\/p>\n<p>Ere\u00f1o-Orbea J, Pang L, Sicard T, Nycholat C, Cui H, Borovsky D, Franconetti A, Jim\u00e9nez-Barbero J, Paulson JC, Julien JP.<\/p>\n<p><em>JACS Au. 2025 Nov 5. 5(11):5524-5537. doi: 10.1021\/jacsau.5c01013.<\/em><\/p>\n<p class=\"title\"><a style=\"color: #000080\" href=\"https:\/\/www.cell.com\/immunity\/fulltext\/S1074-7613(25)00425-X\">Cryo-EM structure of endogenous Pfs230:Pfs48\/45 complex with six antibodies reveals mechanisms of malaria transmission-blocking activity.<\/a><\/p>\n<p>Bekkering ET, Yoo R, Hailemariam S, Heide F, Ivanochko D, Jackman M, Proellochs NI, Stoter R, Wanders OT, van Daalen RC, Inklaar MR, Andrade CM, Jansen PWTC, Vermeulen M, Bousema T, Rubinstein JL, Kooij TWA, Jore MM, Julien JP.<\/p>\n<p><em>Immunity. 2025 Oct 9. 58(11):2899-2916.e10. doi: 10.1016\/j.immuni.2025.09.014.<\/em><\/p>\n<p><em>bioRxiv. 2025 Feb 14. doi: 10.1101\/2025.02.14.638310.<\/em><\/p>\n<p class=\"title\"><a style=\"color: #000080\" href=\"https:\/\/academic.oup.com\/jid\/advance-article-abstract\/doi\/10.1093\/infdis\/jiaf318\/8160841?redirectedFrom=fulltext\">Priming or Boosting Plasmodium falciparum Transmission-Blocking Responses With Recombinant Vaccines or Gametocyte Extract.<\/a><\/p>\n<p>Song Y, Deng B, Long CA, Li Q, Diakite M, Huang WC, Zhou S, Luo Y, Ivanochko D, MacGill RS, Julien JP, Miura K, Lovell J.<\/p>\n<p><em>Journal of Infectious Diseases. 2025 Jun 12. 232(6):1418-1426. doi: 10.1093\/infdis\/jiaf318.<\/em><\/p>\n<p class=\"title\"><a style=\"color: #000080\" href=\"https:\/\/www.nature.com\/articles\/s41594-025-01532-6\">Structural elucidation of full-length Pfs48\/45 in complex with potent monoclonal antibodies isolated from a naturally exposed individual.<\/a><\/p>\n<p>Kucharska I, Ivanochko D, Hailemariam S, Inklaar MR, Kim HR, Teelen K, Stoter R, van de Vegte-Bolmer M, van Gemert GJ, Semesi A, McLeod B, Ki A, Lee WK, Rubinstein JL, Jore MM, Julien JP.<\/p>\n<p><em>Nature Structural &amp; Molecular Biology. 2025 May 22. 32(8):1396-1407. doi: 10.1038\/s41594-025-01532-6.<\/em><\/p>\n<p><em>Research Square. 2023 Nov 30. doi: 10.21203\/rs.3.rs-3605634.<\/em><\/p>\n<p class=\"title\"><a style=\"color: #000080\" href=\"https:\/\/pubs.acs.org\/doi\/10.1021\/acsnano.4c16865\">50-Fold Adjuvant and 20-Fold Antigen Vaccine Dose Sparing from Nanoliposome Display of a Stabilized Malarial Protein Antigen.<\/a><\/p>\n<p>Song Y, Huang WC, Ivanochko D, Li Q, Long C, Zhou L, Julien JP, Miura K, Lovell J.<\/p>\n<p><em>ACS Nano. 2025 Mar 18. 19(10):10103-10112. doi: 10.1021\/acsnano.4c16865.<\/em><\/p>\n<p class=\"title\"><a style=\"color: #000080\" href=\"https:\/\/journals.asm.org\/doi\/10.1128\/spectrum.01333-24\">Persistence and decay of neutralizing antibody responses elicited by SARS-CoV-2 infection and hybrid immunity in a Canadian cohort.<\/a><\/p>\n<p>Nouanesengsy A, Semesi A, Quach K, Ivanochko D, Byrne W, Hwang M, La Neve MR, Leon-Ponte M, Litosh A, Wisener N, Adeli K, Campigotto A, Grunebaum E, McGeer A, Moraes TJ, Sepiashvili L, Upton J, Julien JP, Allen U.<\/p>\n<p><em>Microbiology Spectrum. 2025 Feb 19. 13(4):e0133324. doi: 10.1128\/spectrum.01333-24.<\/em><\/p>\n<p class=\"title\"><a style=\"color: #000080\" href=\"https:\/\/onlinelibrary.wiley.com\/doi\/10.1111\/imr.70001\">Targeting bottlenecks in malaria transmission: antibody-epitope descriptions guide the design of next-generation biomedical interventions.<\/a><\/p>\n<p>Yoo R, Jore MM, Julien JP.<\/p>\n<p><em>Immunological Reviews. 2025 Feb 5. 330(1):e70001. doi: 10.1111\/imr.70001.<\/em><\/p>\n<p class=\"title\"><a style=\"color: #000080\" href=\"https:\/\/www.tandfonline.com\/doi\/full\/10.1080\/21645515.2025.2460749\">PfCSP-Ferritin Nanoparticle Malaria Vaccine Antigen Formulated with Aluminum-salt and CpG 1018\u00ae Adjuvants: Preformulation Characterization, Antigen- Adjuvant Interactions, and Mouse Immunogenicity Studies.<\/a><\/p>\n<p>Hickey JM, Sharma N, Fairlamb M, Doering J, Adewunmi Y, Prieto K, Costa G, Wizel B, Levashina EA, Mantis NJ, Julien JP, Joshi SB, Volkin DB.<\/p>\n<p><em>Human Vaccines &amp; Immunotherapeutics. 2025 Feb 4. 21(1):2460749. doi: 10.1080\/21645515.2025.2460749.<\/em><\/p>\n<p class=\"title\"><a style=\"color: #000080\" href=\"https:\/\/elifesciences.org\/articles\/97865\">Target-agnostic identification of human antibodies to Plasmodium falciparum sexual forms reveals cross stage recognition of glutamate-rich repeats.<\/a><\/p>\n<p>Amen A, Yoo R, Fabra-Garcia A, Bolscher J, Stone WJR, Bally I, Dergan-Dylon S, Kucharska I, de Jong RM, de Bruijni M, Bousema T, King CR, MacGill RS, Sauerwein RW, Julien JP, Poignard P, Jore MM.<\/p>\n<p><em>eLife. 2025 Jan 16. 13:RP97865. doi: 10.7554\/eLife.97865.3.<\/em><\/p>\n<p><em>bioRxiv. 2023 Nov 5. doi: 10.1101\/2023.11.03.565335.<\/em><\/p>\n<\/div><div class=\"nav fusion-mobile-tab-nav\"><ul class=\"nav-tabs\" role=\"tablist\"><li role=\"presentation\"><a class=\"tab-link\" data-toggle=\"tab\" role=\"tab\" aria-controls=\"tab-bbdb76af9e88bd2f8b9\" aria-selected=\"false\" tabindex=\"-1\" id=\"mobile-fusion-tab-2024\" href=\"#tab-bbdb76af9e88bd2f8b9\"><h4 class=\"fusion-tab-heading\">2024<\/h4><\/a><\/li><\/ul><\/div><div class=\"tab-pane fade fusion-clearfix\" role=\"tabpanel\" tabindex=\"0\" aria-labelledby=\"fusion-tab-2024\" id=\"tab-bbdb76af9e88bd2f8b9\">\n<p class=\"title\"><a style=\"color: #000080\" href=\"https:\/\/www.nature.com\/articles\/s41587-024-02466-y\">A general system for targeting MHC class II\u2013antigen complex via a single adaptable loop.<\/a><\/p>\n<p>Du H, Liu J, Jude KM, Yang X, Li Y, Bell B, Yang H, Kassardjian A, Blackson W, Mobedi A, Parekh U, Sperberg A, Julien JP, Mellins E, Garcia KC, Huang P.<\/p>\n<p><em>Nature Biotechnology. 2024 December 13. doi: 10.1038\/s41587-024-02466-y.<\/em><\/p>\n<p><em>bioRxiv. 2024 Jan 30. doi: 10.1101\/2024.01.26.577489.<\/em><\/p>\n<p class=\"title\"><a style=\"color: #000080\" href=\"https:\/\/rupress.org\/jem\/article\/221\/12\/e20240546\/277074\/Human-ITGAV-variants-are-associated-with-immune\">Human ITGAV variants are associated with immune dysregulation, brain abnormalities, and colitis.<\/a><\/p>\n<p>Ghasempour S, Warner N, Guan R, Rodari MM, Ivanochko D, Whittaker Hawkins R, Marwaha A, Nowak JK, Liang Y, Mulder DJ, Stallard L, Li M, Yu DD, Pluthero FG, Batura V, Zhao M, Siddiqui I, Upton JEM, Hulst JM, Kahr WHA, Mendoza-Londono R, Charbit-Henrion F, Hoefsloot LH, Khiat A, Moreira D, Trindade E, do C\u00e9u Espinheira M, Pinto Pais I, Weerts MJA, Douben H, Kotlarz D, Snapper SB, Klein C, Dowling JJ., Julien JP, Joosten M, Cerf-Bensussan N, Freeman SA, Parlato M, van Ham TJ, Muise AM.<\/p>\n<p><em>Journal of Experimental Medicine. 2024 November 11; 221(12): e20240546. doi: 10.1084\/jem.20240546.<\/em><\/p>\n<p class=\"title\"><a style=\"color: #000080\" href=\"https:\/\/www.nature.com\/articles\/s41598-024-73843-5\">A human-serum-free medium can induce more infectious P. falciparum gametocytes than a conventional human-serum-containing medium.<\/a><\/p>\n<p>Miura K, Deng B, Suresh RV, Gebremicale YT, Zhou L, Pham TP, Roche K, Diouf A, Lovell JF, Julien JP, Long CA.<\/p>\n<p><em>Scientific Reports. 2024 September 27; 14, 22052. doi: 10.1038\/s41598-024-73843-5.<\/em><\/p>\n<p class=\"title\"><a style=\"color: #000080\" href=\"https:\/\/www.science.org\/doi\/10.1126\/scitranslmed.adn6605\">A comparative immunological assessment of multiple clinical-stage adjuvants for the R21 malaria vaccine in nonhuman primates.<\/a><\/p>\n<p>Arunachalam PS, Ha NY, Dennison SM, Spreng RL, Seaton KE, Xiao P, Feng Y, Zarnitsyna VI, Kazmin D, Hu M, Santagata JM, Xie X, Rogers K, Shirreff LM, Chottin C, Spencer AJ, Dutta S, Prieto K, Julien JP, Tomai M, Fox CB, Villinger F, Hill AVS, Tomaras GD, Pulendran B.<\/p>\n<p><em>Science Translational Medicine. 2024 July 31; 16(758), adn6605. doi: 10.1126\/scitranslmed.adn6605.<\/em><\/p>\n<p class=\"title\"><a style=\"color: #000080\" href=\"https:\/\/www.mdpi.com\/2073-4468\/13\/3\/57\">Humanization of pan-HLA-DR mAb 44H10 Hinges on Critical Residues in the Antibody Framework.<\/a><\/p>\n<p>Kassardjian A, Ivanochko D, Barber B, Jetha A, Julien JP.<\/p>\n<p><em>Antibodies. 2024 July 16; 13(3), 57. doi: 10.3390\/antib13030057.<\/em><\/p>\n<p class=\"title\"><a style=\"color: #000080\" href=\"https:\/\/link.springer.com\/article\/10.1007\/s40615-023-01903-z\">Disproportionate Rates of COVID-19 Among Black Canadian Communities: Lessons from a Cross-Sectional Study in the First Year of the Pandemic.<\/a><\/p>\n<p>Allen UA, Barton M, Upton J, Bailey A, Campigotto A, Abdulnoor M, Julien JP, Gubbay J, Kissoon N, Litosh A, La Neve MR, Wong P, Allen A, Bailey R, Byrne W, Jagoowani R, Phillips C, Merreles Pulcini M, Polack A, Prescod C, Siddiqi A, Summers A, Thompson K, Thompson S, James C, for the seroMARK Research Group.<\/p>\n<p><em>Journal of Racial and Ethnic Health Disparities. 2024 Jan 22. ofad500.1652. doi: 10.1007\/s40615-023-01903-z.<\/em><\/p>\n<\/div><div class=\"nav fusion-mobile-tab-nav\"><ul class=\"nav-tabs\" role=\"tablist\"><li role=\"presentation\"><a class=\"tab-link\" data-toggle=\"tab\" role=\"tab\" aria-controls=\"tab-bdcb7e7a953a85891f7\" aria-selected=\"false\" tabindex=\"-1\" id=\"mobile-fusion-tab-2023\" href=\"#tab-bdcb7e7a953a85891f7\"><h4 class=\"fusion-tab-heading\">2023<\/h4><\/a><\/li><\/ul><\/div><div class=\"tab-pane fade fusion-clearfix\" role=\"tabpanel\" tabindex=\"0\" aria-labelledby=\"fusion-tab-2023\" id=\"tab-bdcb7e7a953a85891f7\">\n<p class=\"title\"><a style=\"color: #000080\" href=\"https:\/\/www.cell.com\/cell-reports\/fulltext\/S2211-1247(23)01342-6\">Molecular determinants of cross-reactivity and potency by VH3-33 antibodies against the Plasmodium falciparum circumsporozoite protein.<\/a><\/p>\n<p>Thai E, Murugan R, Binter S, Burn Aschner C, Prieto K, Kassardjian A, Obraztsova AS, Kang RW, Flores-Garcia Y, Mathis-Torres S, Li K, Horn GQ, Huntwork RHC, Bolscher JM, de Bruijni MHC, Sauerwein R, Dennison SM, Tomaras GD, Zavala F, Kellam P, Wardemann H,\u00a0<span class=\"highwire-citation-author hw-author-orcid-logo-wrapper has-tooltip hasTooltip\" data-delta=\"19\" data-hasqtip=\"2\"><span class=\"nlm-surname\">Julien JP<\/span><\/span>.<\/p>\n<p><em>Cell Reports. 2023 Oct 28; 42(11), 113330. doi: 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26 (7):1135-1145. doi: 10.1038\/s41591-020-0881-9.<\/em><\/p>\n<p><em>bioRxiv. 2019 Oct 9. doi: 10.1101\/798769.<\/em><\/p>\n<p class=\"title\"><a style=\"color: #000080\" href=\"https:\/\/science.sciencemag.org\/content\/368\/6492\/eaay5051\">De novo protein design enables the precise induction of RSV-neutralizing antibodies.<\/a><\/p>\n<p>Sesterhenn F, Yang C, Bonet J, Cramer JT, Wen X, Wang Y, Chiang CI, Abriata LA, Kucharska I, Castoro G, Vollers SS, Galloux M, Dheilly E, Rosset S, Corth\u00e9sy P, Georgeon S, Villard M, Richard CA, Descamps D, Delgado T, Oricchio E, Rameix-Welti MA, M\u00e1s V, Ervin S, El\u00e9ou\u00ebt JF, Riffault S, Bates JT, Julien JP, Li Y, Jardetzky T, Krey T, Correia BE.<\/p>\n<p><em>Science. 2020 May 15; 368 (6492): eaay5051. doi: 10.1126\/science.aay5051.<\/em><\/p>\n<\/div><div class=\"nav fusion-mobile-tab-nav\"><ul class=\"nav-tabs\" role=\"tablist\"><li role=\"presentation\"><a class=\"tab-link\" data-toggle=\"tab\" role=\"tab\" aria-controls=\"tab-5d37cc70d17531dc115\" aria-selected=\"false\" tabindex=\"-1\" id=\"mobile-fusion-tab-2019\" href=\"#tab-5d37cc70d17531dc115\"><h4 class=\"fusion-tab-heading\">2019<\/h4><\/a><\/li><\/ul><\/div><div class=\"tab-pane fade fusion-clearfix\" role=\"tabpanel\" tabindex=\"0\" aria-labelledby=\"fusion-tab-2019\" id=\"tab-5d37cc70d17531dc115\">\n<p class=\"title\"><a style=\"color: #000080\" href=\"https:\/\/www.nature.com\/articles\/s41467-019-11980-6\">Potent antibody lineage against malaria transmission elicited by human vaccination with Pfs25.<\/a><\/p>\n<p>McLeod B, Miura K, Scally SW, Bosch A, Nguyen N, Shin H, Kim D, Volkmuth W, R\u00e4misch S, Chichester JA, Streatfield S, Woods C, Schief WR, Emerling D, King CR, Julien JP.<\/p>\n<p><em>Nat Commun. 2019 Sep 24; 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U.S.A. 2019 Mar 20; 116(14): 6812-6817. doi: 10.1073\/pnas.1817246116.<\/em><\/p>\n<p class=\"title\"><a style=\"color: #000080\" href=\"https:\/\/www.nature.com\/articles\/s41467-018-07962-9\">Molecular recognition of the native HIV-1 MPER revealed by STED microscopy of single virions.<\/a><\/p>\n<p>Carravilla P, Chojnacki J, Rujas E, Insausti S, Largo E, Waithe D, Apellaniz B, Sicard T, Julien JP, Eggeling C, Nieva JL.<\/p>\n<p><em>Nat Commun. 2019 Jan 8; 10:\u00a078. doi: 10.1038\/s41467-018-07962-9.<\/em><\/p>\n<div class=\"rprt\"><\/div>\n<\/div><div class=\"nav fusion-mobile-tab-nav\"><ul class=\"nav-tabs\" role=\"tablist\"><li role=\"presentation\"><a class=\"tab-link\" data-toggle=\"tab\" role=\"tab\" aria-controls=\"tab-3f37d601f7c349aee65\" aria-selected=\"false\" tabindex=\"-1\" id=\"mobile-fusion-tab-2018\" href=\"#tab-3f37d601f7c349aee65\"><h4 class=\"fusion-tab-heading\">2018<\/h4><\/a><\/li><\/ul><\/div><div class=\"tab-pane fade fusion-clearfix\" role=\"tabpanel\" tabindex=\"0\" aria-labelledby=\"fusion-tab-2018\" id=\"tab-3f37d601f7c349aee65\">\n<p class=\"title\"><a style=\"color: #000080\" href=\"https:\/\/www.nature.com\/articles\/s41467-018-06742-9\">Structural delineation of potent transmission-blocking epitope I on malaria antigen Pfs48\/45.<\/a><\/p>\n<p>Kundu P, Semesi A, Jore MM, Morin MJ, Price VL, Liang A, Li J, Miura K, Sauerwein RW, King CR, Julien JP.<\/p>\n<p><em>Nat Commun. 2018 Oct 26; 9:\u00a04458. doi: 10.1038\/s41467-018-06742-9.<\/em><\/p>\n<p class=\"title\"><a style=\"color: #000080\" href=\"https:\/\/www.jove.com\/video\/57750\/characterization-glycoproteins-with-immunoglobulin-fold-x-ray\">Characterization of Glycoproteins with the Immunoglobulin Fold by X-Ray Crystallography and Biophysical Techniques.<\/a><\/p>\n<p>Ere\u00f1o-Orbea J, Sicard T, Cui H, Akula I, Julien JP.<\/p>\n<p class=\"title\"><em>J Vis Exp.<\/em>\u00a02018 Jul 5; 137: e57750. doi: 10.3791\/57750.<\/p>\n<p class=\"title\"><a style=\"color: #000080\" href=\"http:\/\/science.sciencemag.org\/content\/early\/2018\/06\/06\/science.aar5304\">Antihomotypic affinity maturation improves human B cell responses against a repetitive epitope.<\/a><\/p>\n<p>Imkeller K, Scally SW, Bosch A, Mart\u00ed GP, Costa G, Triller G, Murugan R, Renna V, Jumaa H, Kremsner PG, Sim BKL, Hoffman SL, Mordm\u00fcller B, Levashina E, Julien JP, Wardemann H.<\/p>\n<p class=\"title\"><em>Science<\/em>. 2018 Jun 22; 360(6395): 1358-1362. doi: 10.1126\/science.aar5304. First Release 2018 Jun 7.<\/p>\n<p>Video highlight of manuscript:<\/p>\n<div style=\"width: 1100px;\" class=\"wp-video\"><video class=\"wp-video-shortcode\" id=\"video-17-2\" width=\"1100\" height=\"619\" preload=\"metadata\" controls=\"controls\"><source type=\"video\/mp4\" src=\"https:\/\/lab.research.sickkids.ca\/julien\/wp-content\/uploads\/sites\/24\/2018\/06\/pfcsp_final01.mp4?_=2\" \/><a href=\"https:\/\/lab.research.sickkids.ca\/julien\/wp-content\/uploads\/sites\/24\/2018\/06\/pfcsp_final01.mp4\">https:\/\/lab.research.sickkids.ca\/julien\/wp-content\/uploads\/sites\/24\/2018\/06\/pfcsp_final01.mp4<\/a><\/video><\/div>\n<p class=\"title\"><a style=\"color: #000080\" href=\"https:\/\/www.cell.com\/immunity\/fulltext\/S1074-7613(18)30208-5\">Peek-Peak-Pique: Repeating Motifs of Subtle Variance Are Targets for Potent Malaria Antibodies.<\/a><\/p>\n<p>Scally SW, Julien JP.<\/p>\n<p class=\"title\"><em>Immunity<\/em>. 2018 May 15; 48(5): 851\u2013854. doi: 10.1016\/j.immuni.2018.04.037.<\/p>\n<p class=\"title\"><a style=\"color: #000080\" href=\"http:\/\/jvi.asm.org\/content\/92\/14\/e02261-17.long\">Molecular basis of unusually high neutralization resistance in tier 3 HIV-1 strain 253-11.<\/a><\/p>\n<p>Moyo T, Ere\u00f1o-Orbea J, Jacob RA, Pavillet CE, Kariuki SM, Tangie EN, Julien JP, Dorfman JR.<\/p>\n<p class=\"title\"><em>J Virol<\/em>. 2018 Jun 29; 92(14). pii: e02261-17. doi: 10.1128\/JVI.02261-17.<\/p>\n<p class=\"title\"><a style=\"color: #000080\" href=\"https:\/\/www.sciencedirect.com\/science\/article\/pii\/S0022283617305910\">Structural basis of enhanced crystallizability induced by a molecular chaperone for antibody antigen-binding fragments.<\/a><\/p>\n<p>Ere\u00f1o-Orbea J, Sicard T, Cui H, Carson J, Hermans P, Julien JP.<\/p>\n<p class=\"title\"><em>J Mol Biol<\/em>. 2018 Feb 2; 430(3): 322\u2013336.\u00a0doi: 10.1016\/j.jmb.2017.12.010.<\/p>\n<p class=\"title\"><a style=\"color: #000080\" href=\"https:\/\/rupress.org\/jem\/article\/215\/1\/63\/42471\/Rare-PfCSP-C-terminal-antibodies-induced-by-live\">Rare PfCSP C-terminal antibodies induced by live sporozoite vaccination are ineffective against malaria infection.<\/a><\/p>\n<p>Scally SW, Murugan R, Bosch A, Triller G, Costa G, Mordm\u00fcller B, Kremsner PG, Sim BKL, Hoffman SL, Levashina EA, Wardemann H, Julien JP.<\/p>\n<p class=\"title\"><em>J Exp Med<\/em>. 2018 Jan 2; 215(1): 63\u201375. doi: 10.1084\/jem.20170869.<\/p>\n<div class=\"rprt\"><\/div>\n<\/div><div class=\"nav fusion-mobile-tab-nav\"><ul class=\"nav-tabs\" role=\"tablist\"><li role=\"presentation\"><a class=\"tab-link\" data-toggle=\"tab\" role=\"tab\" aria-controls=\"tab-9786dee369dd6af6724\" aria-selected=\"false\" tabindex=\"-1\" id=\"mobile-fusion-tab-2017\" href=\"#tab-9786dee369dd6af6724\"><h4 class=\"fusion-tab-heading\">2017<\/h4><\/a><\/li><\/ul><\/div><div class=\"tab-pane fade fusion-clearfix\" role=\"tabpanel\" tabindex=\"0\" aria-labelledby=\"fusion-tab-2017\" id=\"tab-9786dee369dd6af6724\">\n<div class=\"rprt\">\n<div class=\"rslt\">\n<p class=\"title\"><a style=\"color: #000080\" href=\"http:\/\/www.cell.com\/immunity\/fulltext\/S1074-7613(17)30484-3\">Natural Parasite Exposure Induces Protective Human Anti-Malarial Antibodies.<\/a><\/p>\n<p>Triller G, Scally SW, Costa G, Pissarev M, Kreschel C, Bosch A, Marois E, Sack BK, Murugan R, Salman AM, Janse CJ, Khan SM, Kappe SHI,\u00a0 Adegnika AA, Mordm\u00fcller B, Levashina EA, Julien JP, Wardemann H.<\/p>\n<p class=\"title\"><em>Immunity<\/em>. 2017 Dec 19; 47(6):1197-1209.e10. doi: 10.1016\/j.immuni.2017.11.007.<\/p>\n<p class=\"title\"><span style=\"color: #000080\"><a style=\"color: #000080\" href=\"https:\/\/www.nature.com\/articles\/s41467-017-01924-3\">Molecular definition of multiple sites of antibody inhibition of malaria transmission-blocking vaccine antigen Pfs25.<\/a><\/span><\/p>\n<p>Scally SW, McLeod B, Bosch A, Miura K, Liang Q, Carroll S, Reponen S, Nguyen N, Giladi E, R\u00e4misch S, Yusibov V, Bradley A, Lemiale F, Schief WR, Emerling D, Kellam P, King CR, Julien JP.<\/p>\n<p class=\"title\"><em>Nat Commun<\/em>. 2017 Nov 16; 8:1568.\u00a0doi: 10.1038\/s41467-017-01924-3.<\/p>\n<p class=\"title\"><span style=\"color: #000080\"><a style=\"color: #000080\" href=\"https:\/\/www.nature.com\/articles\/s41467-017-00836-6\">Molecular basis of human CD22 function and therapeutic targeting.<\/a><\/span><\/p>\n<p>Ere\u00f1o-Orbea J, Sicard T, Cui H, Mazhab-Jafari MT, Benlekbir S, Guarn\u00e9 A, Rubinstein JL, Julien JP.<\/p>\n<p class=\"title\"><em>Nat Commun<\/em>. 2017 Oct 2; 8:764.\u00a0doi: 10.1038\/s41467-017-00836-6.<\/p>\n<p class=\"title\">Video highlight of manuscript:<\/p>\n<div style=\"width: 1100px;\" class=\"wp-video\"><video class=\"wp-video-shortcode\" id=\"video-17-3\" width=\"1100\" height=\"619\" preload=\"metadata\" controls=\"controls\"><source type=\"video\/mp4\" src=\"https:\/\/lab.research.sickkids.ca\/julien\/wp-content\/uploads\/sites\/24\/2018\/05\/CD22_small_3.mp4?_=3\" \/><a href=\"https:\/\/lab.research.sickkids.ca\/julien\/wp-content\/uploads\/sites\/24\/2018\/05\/CD22_small_3.mp4\">https:\/\/lab.research.sickkids.ca\/julien\/wp-content\/uploads\/sites\/24\/2018\/05\/CD22_small_3.mp4<\/a><\/video><\/div>\n<p class=\"title\"><span style=\"color: #000080\"><a style=\"color: #000080\" href=\"https:\/\/www.ncbi.nlm.nih.gov\/pubmed\/28842504\">Functional defects in Clostridium difficile TcdB toxin uptake identify CSPG4 receptor binding determinants.<\/a><\/span><\/p>\n<p class=\"title\">Gupta P, Zhang Z, Sugiman-Marangos SN, Tam J, Raman S, Julien JP, Kroh HK, Lacy DB, Murgolo N, Bekkari K, Therien AG, Hernandez LD, Melnyk RA.<\/p>\n<p class=\"title\"><em>J Biol Chem<\/em>. 2017 Oct 20; 292(42):17290-17301. doi: 10.1074\/jbc.M117.806687.<\/p>\n<p class=\"title\"><span style=\"color: #000080\"><a style=\"color: #000080\" href=\"https:\/\/www.ncbi.nlm.nih.gov\/pubmed\/28834745\">Improving the Immunogenicity of Native-like HIV-1 Envelope Trimers by Hyperstabilization.<\/a><\/span><\/p>\n<p class=\"title\">Torrents de la Pe\u00f1a A, Julien JP, de Taeye SW, Garces F, Guttman M, Ozorowski G, Pritchard LK, Behrens AJ, Go EP, Burger JA, Schermer EE, Sliepen K, Ketas TJ, Pugach P, Yasmeen A, Cottrell CA, Torres JL, Vavourakis CD, van Gils MJ, LaBranche C, Montefiori DC, Desaire H, Crispin M, Klasse PJ, Lee KK, Moore JP, Ward AB, Wilson IA, Sanders RW.<\/p>\n<p class=\"title\"><em>Cell Rep<\/em>. 2017 Aug 22; 20(8):1805-1817. doi: 10.1016\/j.celrep.2017.07.077.<\/p>\n<p class=\"title\"><span style=\"color: #000080\"><a style=\"color: #000080\" href=\"https:\/\/www.ncbi.nlm.nih.gov\/pubmed\/28423342\">A Broadly Neutralizing Antibody Targets the Dynamic HIV Envelope Trimer Apex via a Long, Rigidified, and Anionic \u03b2-Hairpin Structure.<\/a><\/span><\/p>\n<p class=\"title\">Lee JH, Andrabi R, Su CY, Yasmeen A, Julien JP, Kong L, Wu NC, McBride R, Sok D, Pauthner M, Cottrell CA, Nieusma T, Blattner C, Paulson JC, Klasse PJ, Wilson IA, Burton DR, Ward AB.<\/p>\n<p class=\"title\"><em>Immunity<\/em>. 2017 Apr 18; 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PMID: 28423342<\/p>\n<p class=\"title\"><span style=\"color: #000080\"><a style=\"color: #000080\" href=\"https:\/\/www.ncbi.nlm.nih.gov\/pubmed\/28003379\">Key Residues at Third CDR3\u03b2 Position Impact Structure and Antigen Recognition of Human Invariant NK TCRs.<\/a><\/span><\/p>\n<p class=\"title\">Chamoto K, Guo T, Scally SW, Kagoya Y, Ancruzowski M, Wang CH, Rahman MA, Saso K, Butler MO, Chiu PP, Julien JP, Hirano N.<\/p>\n<p class=\"title\"><em><span class=\"jrnl\" title=\"Journal of immunology (Baltimore, Md. : 1950)\">J Immunol<\/span><\/em>. 2017 Feb 1;198(3):1056-1065. doi: 10.4049\/jimmunol.1601556. PMID: 28003379.<\/p>\n<\/div>\n<\/div>\n<\/div><div class=\"nav fusion-mobile-tab-nav\"><ul class=\"nav-tabs\" role=\"tablist\"><li role=\"presentation\"><a class=\"tab-link\" data-toggle=\"tab\" role=\"tab\" aria-controls=\"tab-ffd7a97064bd3c2206d\" aria-selected=\"false\" tabindex=\"-1\" id=\"mobile-fusion-tab-2016\" href=\"#tab-ffd7a97064bd3c2206d\"><h4 class=\"fusion-tab-heading\">2016<\/h4><\/a><\/li><\/ul><\/div><div class=\"tab-pane fade fusion-clearfix\" role=\"tabpanel\" tabindex=\"0\" aria-labelledby=\"fusion-tab-2016\" id=\"tab-ffd7a97064bd3c2206d\">\n<div class=\"rprt\">\n<div class=\"rslt\">\n<p class=\"title\"><span style=\"color: #000080\"><a style=\"color: #000080\" href=\"https:\/\/www.ncbi.nlm.nih.gov\/pubmed\/27798168\">Discrete TCR Binding Kinetics Control Invariant NKT Cell Selection and Central Priming.<\/a><\/span><\/p>\n<p class=\"title\">Cruz Tleugabulova M, Escalante NK, Deng S, Fieve S, Ere\u00f1o-Orbea J, Savage PB, Julien JP, Mallevaey T.<\/p>\n<p class=\"title\"><em>J Immunol.<\/em> 2016 Nov 15;197(10):3959-3969. doi: 10.4049\/jimmunol.1601382. PMID: 27798168.<\/p>\n<p class=\"title\"><span style=\"color: #000080\"><a style=\"color: #000080\" href=\"http:\/\/journals.plos.org\/plospathogens\/article?id=10.1371\/journal.ppat.1005815\">Minimally mutated HIV-1 broadly neutralizing antibodies to guide reductionist vaccine design<\/a><\/span>.<\/p>\n<p class=\"title\">Jardine JG*, Sok D*, Julien J-P*, Briney B*, Sarkar A, Liang C-H, Scherer EA, Henry Dunand CJ, Adachi Y, Diwanji D, Hsueh J, Jones M, Kalyuzhniy O, Kubitz M, Spencer S, Pauthner M, Saye-Francisco KL, Sesterhenn F, Wilson PC, Galloway DM, Stanfield RL, Wilson IA, Burton DR, Schief WR.<\/p>\n<p class=\"title\"><em>PLoS Pathog<\/em>. 2016 Aug 25;12(8):e1005815. doi:10.1371\/journal.ppat.1005815.\u00a0PMID: 27560183.<\/p>\n<p class=\"title\"><span style=\"color: #000080\"><a style=\"color: #000080\" href=\"http:\/\/www.ncbi.nlm.nih.gov\/pubmed\/27462807\">The structural basis of modified nucleosome recognition by 53BP1<\/a>.<\/span><\/p>\n<p class=\"title\">Wilson MD, Benlekbir S, Fradet-Turcotte A, Sherker A, Julien JP, McEwan A, Noordermeer SM, Sicheri F, Rubinstein JL, Durocher D.<\/p>\n<p class=\"title\"><em>Nature<\/em>. 2016 Jul 27;536(7614):100-103. doi: 10.1038\/nature18951.\u00a0PMID: 27462807<\/p>\n<p class=\"title\"><span style=\"color: #000080\"><a style=\"color: #000080\" href=\"http:\/\/www.polyplus-transfection.com\/wp-content\/uploads\/2015\/09\/FectoPRO-Technical-Note-031716.pdf\">Optimization of Glycoprotein Expression by Transient Transfection in HEK 293F\/S suspension cells<\/a>.<\/span><\/p>\n<p class=\"title\">Akula\u00a0I, Julien\u00a0JP<\/p>\n<p class=\"title\"><em><span class=\"jrnl\" title=\"Science (New York, N.Y.)\">Polyplus Transfections<\/span><\/em>. 2016 May\u00a025:1-6.<\/p>\n<p class=\"title\"><span style=\"color: #000080\"><a style=\"color: #000080\" href=\"http:\/\/www.ncbi.nlm.nih.gov\/pubmed\/27013733\">HIV-1 broadly neutralizing antibody precursor B cells revealed by germline-targeting immunogen.<\/a><\/span><\/p>\n<div class=\"supp\">\n<p class=\"desc\">Jardine JG, Kulp DW, Havenar-Daughton C, Sarkar A, Briney B, Sok D, Sesterhenn F, Ere\u00f1o-Orbea J, Kalyuzhniy O, Deresa I, Hu X, Spencer S, Jones M, Georgeson E, Adachi Y, Kubitz M, deCamp AC, Julien JP, Wilson IA, Burton DR, Crotty S, Schief WR.<\/p>\n<p class=\"details\"><em><span class=\"jrnl\" title=\"Science (New York, N.Y.)\">Science<\/span><\/em>. 2016 Mar 25;351(6280):1458-63. doi: 10.1126\/science.aad9195.\u00a0PMID:27013733<\/p>\n<\/div>\n<\/div>\n<\/div>\n<div class=\"rprt\">\n<div class=\"rslt\">\n<p class=\"title\"><span style=\"color: #000080\"><a style=\"color: #000080\" href=\"http:\/\/www.ncbi.nlm.nih.gov\/pubmed\/26934472\">EspP, an Extracellular Serine Protease from Enterohemorrhagic E. coli, Reduces Coagulation Factor Activities, Reduces Clot Strength, and Promotes Clot Lysis.<\/a><\/span><\/p>\n<div class=\"supp\">\n<p class=\"desc\">Kuo KH, Khan S, Rand ML, Mian HS, Brnjac E, Sandercock LE, Akula I, Julien JP, Pai EF, Chesney AE.<\/p>\n<p class=\"details\"><em><span class=\"jrnl\" title=\"PloS one\">PLoS One<\/span><\/em>. 2016 Mar 2;11(3):e0149830. doi: 10.1371\/journal.pone.0149830. eCollection 2016.\u00a0PMID:26934472<\/p>\n<\/div>\n<\/div>\n<\/div>\n<\/div><div class=\"nav fusion-mobile-tab-nav\"><ul class=\"nav-tabs\" role=\"tablist\"><li role=\"presentation\"><a class=\"tab-link\" data-toggle=\"tab\" role=\"tab\" aria-controls=\"tab-b499ed44594057c66a0\" aria-selected=\"false\" tabindex=\"-1\" id=\"mobile-fusion-tab-2015\" href=\"#tab-b499ed44594057c66a0\"><h4 class=\"fusion-tab-heading\">2015<\/h4><\/a><\/li><\/ul><\/div><div class=\"tab-pane fade fusion-clearfix\" role=\"tabpanel\" tabindex=\"0\" aria-labelledby=\"fusion-tab-2015\" id=\"tab-b499ed44594057c66a0\">\n<div class=\"rprt\">\n<div class=\"rslt\">\n<p class=\"title\"><span style=\"color: #000080\"><a style=\"color: #000080\" href=\"http:\/\/www.ncbi.nlm.nih.gov\/pubmed\/26687358\">Immunogenicity of Stabilized HIV-1 Envelope Trimers with Reduced Exposure of Non-neutralizing Epitopes.<\/a><\/span><\/p>\n<div class=\"supp\">\n<p class=\"desc\">de Taeye SW, Ozorowski G, Torrents de la Pe\u00f1a A, Guttman M, Julien JP, van den Kerkhof TL, Burger JA, Pritchard LK, Pugach P, Yasmeen A, Crampton J, Hu J, Bontjer I, Torres JL, Arendt H, DeStefano J, Koff WC, Schuitemaker H, Eggink D, Berkhout B, Dean H, LaBranche C, Crotty S, Crispin M, Montefiori DC, Klasse PJ, Lee KK, Moore JP, Wilson IA, Ward AB, Sanders RW.<\/p>\n<p class=\"details\"><em><span class=\"jrnl\" title=\"Cell\">Cell<\/span><\/em>. 2015 Dec 17;163(7):1702-15. doi: 10.1016\/j.cell.2015.11.056.\u00a0PMID:26687358<\/p>\n<p class=\"details\">\n<\/div>\n<\/div>\n<\/div>\n<div class=\"rprt\">\n<div class=\"rslt\">\n<p class=\"title\"><span style=\"color: #000080\"><a style=\"color: #000080\" href=\"http:\/\/www.ncbi.nlm.nih.gov\/pubmed\/26372963\">Design and structure of two HIV-1 clade C SOSIP.664 trimers that increase the arsenal of native-like Env immunogens.<\/a><\/span><\/p>\n<div class=\"supp\">\n<p class=\"desc\">Julien JP, Lee JH, Ozorowski G, Hua Y, Torrents de la Pe\u00f1a A, de Taeye SW, Nieusma T, Cupo A, Yasmeen A, Golabek M, Pugach P, Klasse PJ, Moore JP, Sanders RW, Ward AB, Wilson IA.<\/p>\n<p class=\"details\"><em><span class=\"jrnl\" title=\"Proceedings of the National Academy of Sciences of the United States of America\">Proc Natl Acad Sci U S A<\/span><\/em>. 2015 Sep 22;112(38):11947-52. doi: 10.1073\/pnas.1507793112. Epub 2015 Sep 8.\u00a0PMID:26372963<\/p>\n<p class=\"details\">\n<\/div>\n<\/div>\n<\/div>\n<div class=\"rprt\">\n<div class=\"rslt\">\n<p class=\"title\"><span style=\"color: #000080\"><a style=\"color: #000080\" href=\"http:\/\/www.ncbi.nlm.nih.gov\/pubmed\/26288832\">Origins of a Vaccine-Induced, Human Anti-HIV-1 Antibody.<\/a><\/span><\/p>\n<div class=\"supp\">\n<p class=\"desc\">Julien JP.<\/p>\n<p class=\"details\"><em><span class=\"jrnl\" title=\"EBioMedicine\">EBioMedicine<\/span><\/em>. 2015 Jul 16;2(7):632-3. doi: 10.1016\/j.ebiom.2015.07.019. eCollection 2015 Jul.\u00a0PMID:26288832<\/p>\n<p class=\"details\">\n<\/div>\n<\/div>\n<\/div>\n<div class=\"rprt\">\n<div class=\"rslt\">\n<p class=\"title\"><span style=\"color: #000080\"><a style=\"color: #000080\" href=\"http:\/\/www.ncbi.nlm.nih.gov\/pubmed\/26089353\">HIV-1 VACCINES. HIV-1 neutralizing antibodies induced by native-like envelope trimers.<\/a><\/span><\/p>\n<div class=\"supp\">\n<p class=\"desc\">Sanders RW, van Gils MJ, Derking R, Sok D, Ketas TJ, Burger JA, Ozorowski G, Cupo A, Simonich C, Goo L, Arendt H, Kim HJ, Lee JH, Pugach P, Williams M, Debnath G, Moldt B, van Breemen MJ, Isik G, Medina-Ram\u00edrez M, Back JW, Koff WC, Julien JP, Rakasz EG, Seaman MS, Guttman M, Lee KK, Klasse PJ, LaBranche C, Schief WR, Wilson IA, Overbaugh J, Burton DR, Ward AB, Montefiori DC, Dean H, Moore JP.<\/p>\n<p class=\"details\"><em><span class=\"jrnl\" title=\"Science (New York, N.Y.)\">Science<\/span><\/em>. 2015 Jul 10;349(6244):aac4223. doi: 10.1126\/science.aac4223. Epub 2015 Jun 18.\u00a0PMID:26089353<\/p>\n<\/div>\n<\/div>\n<\/div>\n<div class=\"rprt\">\n<div class=\"rslt\">\n<p class=\"title\"><span style=\"color: #000080\"><a style=\"color: #000080\" href=\"http:\/\/www.ncbi.nlm.nih.gov\/pubmed\/25985274\">Redesigned HIV antibodies exhibit enhanced neutralizing potency and breadth.<\/a><\/span><\/p>\n<div class=\"supp\">\n<p class=\"desc\">Willis JR, Sapparapu G, Murrell S, Julien JP, Singh V, King HG, Xia Y, Pickens JA, LaBranche CC, Slaughter JC, Montefiori DC, Wilson IA, Meiler J, Crowe JE Jr.<\/p>\n<p class=\"details\"><em><span class=\"jrnl\" title=\"The Journal of clinical investigation\">J Clin Invest<\/span><\/em>. 2015 Jun;125(6):2523-31. doi: 10.1172\/JCI80693. Epub 2015 May 18.\u00a0PMID:25985274<\/p>\n<\/div>\n<\/div>\n<\/div>\n<div class=\"rprt\">\n<div class=\"rslt\">\n<p class=\"title\"><span style=\"color: #000080\"><a style=\"color: #000080\" href=\"http:\/\/www.ncbi.nlm.nih.gov\/pubmed\/25807248\">Comprehensive antigenic map of a cleaved soluble HIV-1 envelope trimer.<\/a><\/span><\/p>\n<div class=\"supp\">\n<p class=\"desc\">Derking R, Ozorowski G, Sliepen K, Yasmeen A, Cupo A, Torres JL, Julien JP, Lee JH, van Montfort T, de Taeye SW, Connors M, Burton DR, Wilson IA, Klasse PJ, Ward AB, Moore JP, Sanders RW.<\/p>\n<p class=\"details\"><em><span class=\"jrnl\" title=\"PLoS pathogens\">PLoS Pathog<\/span><\/em>. 2015 Mar 25;11(3):e1004767. doi: 10.1371\/journal.ppat.1004767. eCollection 2015 Mar.\u00a0PMID:25807248<\/p>\n<\/div>\n<\/div>\n<\/div>\n<div class=\"rprt\">\n<div class=\"rslt\">\n<p class=\"title\"><span style=\"color: #000080\"><a style=\"color: #000080\" href=\"http:\/\/www.ncbi.nlm.nih.gov\/pubmed\/25652336\">Antibody potency relates to the ability to recognize the closed, pre-fusion form of HIV Env.<\/a><\/span><\/p>\n<div class=\"supp\">\n<p class=\"desc\">Guttman M, Cupo A, Julien JP, Sanders RW, Wilson IA, Moore JP, Lee KK.<\/p>\n<p class=\"details\"><em><span class=\"jrnl\" title=\"Nature communications\">Nat Commun<\/span><\/em>. 2015 Feb 5;6:6144. doi: 10.1038\/ncomms7144.\u00a0PMID:25652336<\/p>\n<\/div>\n<\/div>\n<\/div>\n<div class=\"rprt\">\n<div class=\"rslt\">\n<p class=\"title\"><span style=\"color: #000080\"><a style=\"color: #000080\" href=\"http:\/\/www.ncbi.nlm.nih.gov\/pubmed\/25589637\">A native-like SOSIP.664 trimer based on an HIV-1 subtype B env gene.<\/a><\/span><\/p>\n<div class=\"supp\">\n<p class=\"desc\">Pugach P, Ozorowski G, Cupo A, Ringe R, Yasmeen A, de Val N, Derking R, Kim HJ, Korzun J, Golabek M, de Los Reyes K, Ketas TJ, Julien JP, Burton DR, Wilson IA, Sanders RW, Klasse PJ, Ward AB, Moore JP.<\/p>\n<p class=\"details\"><em><span class=\"jrnl\" title=\"Journal of virology\">J Virol<\/span><\/em>. 2015 Mar;89(6):3380-95. doi: 10.1128\/JVI.03473-14. Epub 2015 Jan 14.\u00a0PMID:25589637<\/p>\n<\/div>\n<\/div>\n<\/div>\n<\/div><div class=\"nav fusion-mobile-tab-nav\"><ul class=\"nav-tabs\" role=\"tablist\"><li role=\"presentation\"><a class=\"tab-link\" data-toggle=\"tab\" role=\"tab\" aria-controls=\"tab-835873251a38f2b70c8\" aria-selected=\"false\" tabindex=\"-1\" id=\"mobile-fusion-tab-2014\" href=\"#tab-835873251a38f2b70c8\"><h4 class=\"fusion-tab-heading\">2014<\/h4><\/a><\/li><\/ul><\/div><div class=\"tab-pane fade fusion-clearfix\" role=\"tabpanel\" tabindex=\"0\" aria-labelledby=\"fusion-tab-2014\" id=\"tab-835873251a38f2b70c8\">\n<div class=\"rprt\">\n<div class=\"rslt\">\n<p class=\"title\"><span style=\"color: #000080\"><a style=\"color: #000080\" href=\"http:\/\/www.ncbi.nlm.nih.gov\/pubmed\/25422458\">Recombinant HIV envelope trimer selects for quaternary-dependent antibodies targeting the trimer apex.<\/a><\/span><\/p>\n<div class=\"supp\">\n<p class=\"desc\">Sok D, van Gils MJ, Pauthner M, Julien JP, Saye-Francisco KL, Hsueh J, Briney B, Lee JH, Le KM, Lee PS, Hua Y, Seaman MS, Moore JP, Ward AB, Wilson IA, Sanders RW, Burton DR.<\/p>\n<p class=\"details\"><em><span class=\"jrnl\" title=\"Proceedings of the National Academy of Sciences of the United States of America\">Proc Natl Acad Sci U S A<\/span><\/em>. 2014 Dec 9;111(49):17624-9. doi: 10.1073\/pnas.1415789111. Epub 2014 Nov 24.\u00a0PMID:25422458<\/p>\n<p class=\"details\">\n<\/div>\n<\/div>\n<\/div>\n<div class=\"rprt\">\n<div class=\"rslt\">\n<p class=\"title\"><span style=\"color: #000080\"><a style=\"color: #000080\" href=\"http:\/\/www.ncbi.nlm.nih.gov\/pubmed\/25259921\">Structural evolution of glycan recognition by a family of potent HIV antibodies.<\/a><\/span><\/p>\n<div class=\"supp\">\n<p class=\"desc\">Garces F, Sok D, Kong L, McBride R, Kim HJ, Saye-Francisco KF, Julien JP, Hua Y, Cupo A, Moore JP, Paulson JC, Ward AB, Burton DR, Wilson IA.<\/p>\n<p class=\"details\"><em><span class=\"jrnl\" title=\"Cell\">Cell<\/span><\/em>. 2014 Sep 25;159(1):69-79. doi: 10.1016\/j.cell.2014.09.009.\u00a0PMID:25259921<\/p>\n<p class=\"details\">\n<\/div>\n<\/div>\n<\/div>\n<div class=\"rprt\">\n<div class=\"rslt\">\n<p class=\"title\"><span style=\"color: #000080\"><a style=\"color: #000080\" href=\"http:\/\/www.ncbi.nlm.nih.gov\/pubmed\/24965454\">Structure of 2G12 Fab2 in complex with soluble and fully glycosylated HIV-1 Env by negative-stain single-particle electron microscopy.<\/a><\/span><\/p>\n<div class=\"supp\">\n<p class=\"desc\">Murin CD, Julien JP, Sok D, Stanfield RL, Khayat R, Cupo A, Moore JP, Burton DR, Wilson IA, Ward AB.<\/p>\n<p class=\"details\"><em><span class=\"jrnl\" title=\"Journal of virology\">J Virol<\/span><\/em>. 2014 Sep 1;88(17):10177-88. doi: 10.1128\/JVI.01229-14. Epub 2014 Jun 25.\u00a0PMID:24965454<\/p>\n<p class=\"details\">\n<\/div>\n<\/div>\n<\/div>\n<div class=\"rprt\">\n<div class=\"rslt\">\n<p class=\"title\"><span style=\"color: #000080\"><a style=\"color: #000080\" href=\"http:\/\/www.ncbi.nlm.nih.gov\/pubmed\/24931470\">CD4-induced activation in a soluble HIV-1 Env trimer.<\/a><\/span><\/p>\n<div class=\"supp\">\n<p class=\"desc\">Guttman M, Garcia NK, Cupo A, Matsui T, Julien JP, Sanders RW, Wilson IA, Moore JP, Lee KK.<\/p>\n<p class=\"details\"><em><span class=\"jrnl\" title=\"Structure (London, England : 1993)\">Structure<\/span><\/em>. 2014 Jul 8;22(7):974-84. doi: 10.1016\/j.str.2014.05.001. Epub 2014 Jun 12.\u00a0PMID:24931470<\/p>\n<p class=\"details\">\n<\/div>\n<\/div>\n<\/div>\n<div class=\"rprt\">\n<div class=\"rslt\">\n<p class=\"title\"><span style=\"color: #000080\"><a style=\"color: #000080\" href=\"http:\/\/www.ncbi.nlm.nih.gov\/pubmed\/24884783\">Differential binding of neutralizing and non-neutralizing antibodies to native-like soluble HIV-1 Env trimers, uncleaved Env proteins, and monomeric subunits.<\/a><\/span><\/p>\n<div class=\"supp\">\n<p class=\"desc\">Yasmeen A, Ringe R, Derking R, Cupo A, Julien JP, Burton DR, Ward AB, Wilson IA, Sanders RW, Moore JP, Klasse PJ.<\/p>\n<p class=\"details\"><em><span class=\"jrnl\" title=\"Retrovirology\">Retrovirology<\/span><\/em>. 2014 May 29;11:41. doi: 10.1186\/1742-4690-11-41.\u00a0PMID:24884783<\/p>\n<p class=\"details\">\n<\/div>\n<\/div>\n<\/div>\n<div class=\"rprt\">\n<div class=\"rslt\">\n<p class=\"title\"><span style=\"color: #000080\"><a style=\"color: #000080\" href=\"http:\/\/www.ncbi.nlm.nih.gov\/pubmed\/24828077\">Promiscuous glycan site recognition by antibodies to the high-mannose patch of gp120 broadens neutralization of HIV.<\/a><\/span><\/p>\n<div class=\"supp\">\n<p class=\"desc\">Sok D, Doores KJ, Briney B, Le KM, Saye-Francisco KL, Ramos A, Kulp DW, Julien JP, Menis S, Wickramasinghe L, Seaman MS, Schief WR, Wilson IA, Poignard P, Burton DR.<\/p>\n<p class=\"details\"><em><span class=\"jrnl\" title=\"Science translational medicine\">Sci Transl Med<\/span><\/em>. 2014 May 14;6(236):236ra63. doi: 10.1126\/scitranslmed.3008104.\u00a0PMID:24828077<\/p>\n<p class=\"details\">\n<\/div>\n<\/div>\n<\/div>\n<div class=\"rprt\">\n<div class=\"rslt\">\n<p class=\"title\"><span style=\"color: #000080\"><a style=\"color: #000080\" href=\"http:\/\/www.ncbi.nlm.nih.gov\/pubmed\/24768348\">Structural delineation of a quaternary, cleavage-dependent epitope at the gp41-gp120 interface on intact HIV-1 Env trimers.<\/a><\/span><\/p>\n<div class=\"supp\">\n<p class=\"desc\">Blattner C, Lee JH, Sliepen K, Derking R, Falkowska E, de la Pe\u00f1a AT, Cupo A, Julien JP, van Gils M, Lee PS, Peng W, Paulson JC, Poignard P, Burton DR, Moore JP, Sanders RW, Wilson IA, Ward AB.<\/p>\n<p class=\"details\"><em><span class=\"jrnl\" title=\"Immunity\">Immunity<\/span><\/em>. 2014 May 15;40(5):669-80. doi: 10.1016\/j.immuni.2014.04.008. Epub 2014 Apr 24.\u00a0PMID:24768348<\/p>\n<p class=\"details\">\n<\/div>\n<\/div>\n<\/div>\n<\/div><div class=\"nav fusion-mobile-tab-nav\"><ul class=\"nav-tabs\" role=\"tablist\"><li role=\"presentation\"><a class=\"tab-link\" data-toggle=\"tab\" role=\"tab\" aria-controls=\"tab-e00d04916de5f6293f2\" aria-selected=\"false\" tabindex=\"-1\" id=\"mobile-fusion-tab-2013\" href=\"#tab-e00d04916de5f6293f2\"><h4 class=\"fusion-tab-heading\">2013<\/h4><\/a><\/li><\/ul><\/div><div class=\"tab-pane fade fusion-clearfix\" role=\"tabpanel\" tabindex=\"0\" aria-labelledby=\"fusion-tab-2013\" id=\"tab-e00d04916de5f6293f2\">\n<div class=\"rprt\">\n<div class=\"rslt\">\n<p class=\"title\"><span style=\"color: #000080\"><a style=\"color: #000080\" href=\"http:\/\/www.ncbi.nlm.nih.gov\/pubmed\/24278016\">The effects of somatic hypermutation on neutralization and binding in the PGT121 family of broadly neutralizing HIV antibodies.<\/a><\/span><\/p>\n<div class=\"supp\">\n<p class=\"desc\">Sok D, Laserson U, Laserson J, Liu Y, Vigneault F, Julien JP, Briney B, Ramos A, Saye KF, Le K, Mahan A, Wang S, Kardar M, Yaari G, Walker LM, Simen BB, St John EP, Chan-Hui PY, Swiderek K, Kleinstein SH, Alter G, Seaman MS, Chakraborty AK, Koller D, Wilson IA, Church GM, Burton DR, Poignard P.<\/p>\n<p class=\"details\"><em><span class=\"jrnl\" title=\"PLoS pathogens\">PLoS Pathog<\/span><\/em>. 2013;9(11):e1003754. doi: 10.1371\/journal.ppat.1003754. Epub 2013 Nov 21. Erratum in: PLoS Pathog. 2013 Dec;9(12). doi:10.1371\/annotation\/f1f8c791-61e9-45c6-a455-92c6dadf9f06. Kleinstein, Stephen H [corrected to Kleinstein, Steven H].\u00a0PMID:24278016<\/p>\n<p class=\"details\">\n<\/div>\n<\/div>\n<\/div>\n<div class=\"rprt\">\n<div class=\"rslt\">\n<p class=\"title\"><span style=\"color: #000080\"><a style=\"color: #000080\" href=\"http:\/\/www.ncbi.nlm.nih.gov\/pubmed\/24179160\">Cryo-EM structure of a fully glycosylated soluble cleaved HIV-1 envelope trimer.<\/a><\/span><\/p>\n<div class=\"supp\">\n<p class=\"desc\">Lyumkis D, Julien JP, de Val N, Cupo A, Potter CS, Klasse PJ, Burton DR, Sanders RW, Moore JP, Carragher B, Wilson IA, Ward AB.<\/p>\n<p class=\"details\"><em><span class=\"jrnl\" title=\"Science (New York, N.Y.)\">Science<\/span><\/em>. 2013 Dec 20;342(6165):1484-90. doi: 10.1126\/science.1245627. Epub 2013 Oct 31.\u00a0PMID:24179160<\/p>\n<p class=\"details\">\n<\/div>\n<\/div>\n<\/div>\n<div class=\"rprt\">\n<div class=\"rslt\">\n<p class=\"title\"><span style=\"color: #000080\"><a style=\"color: #000080\" href=\"http:\/\/www.ncbi.nlm.nih.gov\/pubmed\/24179159\">Crystal structure of a soluble cleaved HIV-1 envelope trimer.<\/a><\/span><\/p>\n<div class=\"supp\">\n<p class=\"desc\">Julien JP, Cupo A, Sok D, Stanfield RL, Lyumkis D, Deller MC, Klasse PJ, Burton DR, Sanders RW, Moore JP, Ward AB, Wilson IA.<\/p>\n<p class=\"details\"><em><span class=\"jrnl\" title=\"Science (New York, N.Y.)\">Science<\/span><\/em>. 2013 Dec 20;342(6165):1477-83. doi: 10.1126\/science.1245625. Epub 2013 Oct 31.\u00a0PMID:24179159<\/p>\n<p class=\"details\">\n<\/div>\n<div class=\"aux\">\n<div class=\"resc\">\n<div class=\"rprt\">\n<div class=\"rslt\">\n<p class=\"title\"><span style=\"color: #000080\"><a style=\"color: #000080\" href=\"http:\/\/www.ncbi.nlm.nih.gov\/pubmed\/24145402\">Cleavage strongly influences whether soluble HIV-1 envelope glycoprotein trimers adopt a native-like conformation.<\/a><\/span><\/p>\n<div class=\"supp\">\n<p class=\"desc\">Ringe RP, Sanders RW, Yasmeen A, Kim HJ, Lee JH, Cupo A, Korzun J, Derking R, van Montfort T, Julien JP, Wilson IA, Klasse PJ, Ward AB, Moore JP.<\/p>\n<p class=\"details\"><em><span class=\"jrnl\" title=\"Proceedings of the National Academy of Sciences of the United States of America\">Proc Natl Acad Sci U S A<\/span><\/em>. 2013 Nov 5;110(45):18256-61. doi: 10.1073\/pnas.1314351110. Epub 2013 Oct 21.\u00a0PMID:24145402<\/p>\n<p class=\"details\">\n<\/div>\n<\/div>\n<\/div>\n<div class=\"rprt\">\n<div class=\"rslt\">\n<p class=\"title\"><span style=\"color: #000080\"><a style=\"color: #000080\" href=\"http:\/\/www.ncbi.nlm.nih.gov\/pubmed\/24068931\">A next-generation cleaved, soluble HIV-1 Env trimer, BG505 SOSIP.664 gp140, expresses multiple epitopes for broadly neutralizing but not non-neutralizing antibodies.<\/a><\/span><\/p>\n<div class=\"supp\">\n<p class=\"desc\">Sanders RW, Derking R, Cupo A, Julien JP, Yasmeen A, de Val N, Kim HJ, Blattner C, de la Pe\u00f1a AT, Korzun J, Golabek M, de Los Reyes K, Ketas TJ, van Gils MJ, King CR, Wilson IA, Ward AB, Klasse PJ, Moore JP.<\/p>\n<p class=\"details\"><em><span class=\"jrnl\" title=\"PLoS pathogens\">PLoS Pathog<\/span><\/em>. 2013 Sep;9(9):e1003618. doi: 10.1371\/journal.ppat.1003618. Epub 2013 Sep 19.\u00a0PMID:24068931<\/p>\n<p class=\"details\">\n<\/div>\n<\/div>\n<\/div>\n<div class=\"rprt\">\n<div class=\"rslt\">\n<p class=\"title\"><span style=\"color: #000080\"><a style=\"color: #000080\" href=\"http:\/\/www.ncbi.nlm.nih.gov\/pubmed\/23824825\">Ebolavirus VP35 coats the backbone of double-stranded RNA for interferon antagonism.<\/a><\/span><\/p>\n<div class=\"supp\">\n<p class=\"desc\">Bale S, Julien JP, Bornholdt ZA, Krois AS, Wilson IA, Saphire EO.<\/p>\n<p class=\"details\"><em><span class=\"jrnl\" title=\"Journal of virology\">J Virol<\/span><\/em>. 2013 Sep;87(18):10385-8. doi: 10.1128\/JVI.01452-13. Epub 2013 Jul 3.\u00a0PMID:23824825<\/p>\n<p class=\"details\">\n<\/div>\n<\/div>\n<\/div>\n<div class=\"rprt\">\n<div class=\"rslt\">\n<p class=\"title\"><span style=\"color: #000080\"><a style=\"color: #000080\" href=\"http:\/\/www.ncbi.nlm.nih.gov\/pubmed\/23824824\">Influences on trimerization and aggregation of soluble, cleaved HIV-1 SOSIP envelope glycoprotein.<\/a><\/span><\/p>\n<div class=\"supp\">\n<p class=\"desc\">Klasse PJ, Depetris RS, Pejchal R, Julien JP, Khayat R, Lee JH, Marozsan AJ, Cupo A, Cocco N, Korzun J, Yasmeen A, Ward AB, Wilson IA, Sanders RW, Moore JP.<\/p>\n<p class=\"details\"><em><span class=\"jrnl\" title=\"Journal of virology\">J Virol<\/span><\/em>. 2013 Sep;87(17):9873-85. doi: 10.1128\/JVI.01226-13. Epub 2013 Jul 3.\u00a0PMID:23824824<\/p>\n<p class=\"details\">\n<\/div>\n<\/div>\n<\/div>\n<div class=\"rprt\">\n<div class=\"rslt\">\n<p class=\"title\"><span style=\"color: #000080\"><a style=\"color: #000080\" href=\"http:\/\/www.ncbi.nlm.nih.gov\/pubmed\/23824817\">Structural characterization of cleaved, soluble HIV-1 envelope glycoprotein trimers.<\/a><\/span><\/p>\n<div class=\"supp\">\n<p class=\"desc\">Khayat R, Lee JH, Julien JP, Cupo A, Klasse PJ, Sanders RW, Moore JP, Wilson IA, Ward AB.<\/p>\n<p class=\"details\"><em><span class=\"jrnl\" title=\"Journal of virology\">J Virol<\/span><\/em>. 2013 Sep;87(17):9865-72. doi: 10.1128\/JVI.01222-13. Epub 2013 Jul 3.\u00a0PMID:23824817<\/p>\n<p class=\"details\">\n<\/div>\n<\/div>\n<\/div>\n<div class=\"rprt\">\n<div class=\"rslt\">\n<p class=\"title\"><span style=\"color: #000080\"><a style=\"color: #000080\" href=\"http:\/\/www.ncbi.nlm.nih.gov\/pubmed\/23708606\">Supersite of immune vulnerability on the glycosylated face of HIV-1 envelope glycoprotein gp120.<\/a><\/span><\/p>\n<div class=\"supp\">\n<p class=\"desc\">Kong L, Lee JH, Doores KJ, Murin CD, Julien JP, McBride R, Liu Y, Marozsan A, Cupo A, Klasse PJ, Hoffenberg S, Caulfield M, King CR, Hua Y, Le KM, Khayat R, Deller MC, Clayton T, Tien H, Feizi T, Sanders RW, Paulson JC, Moore JP, Stanfield RL, Burton DR, Ward AB, Wilson IA.<\/p>\n<p class=\"details\"><em><span class=\"jrnl\" title=\"Nature structural &amp; molecular biology\">Nat Struct Mol Biol<\/span><\/em>. 2013 Jul;20(7):796-803. doi: 10.1038\/nsmb.2594. Epub 2013 May 26.\u00a0PMID:23708606<\/p>\n<p class=\"details\">\n<\/div>\n<\/div>\n<\/div>\n<div class=\"rprt\">\n<div class=\"rslt\">\n<p class=\"title\"><span style=\"color: #000080\"><a style=\"color: #000080\" href=\"http:\/\/www.ncbi.nlm.nih.gov\/pubmed\/23658524\">Broadly neutralizing antibody PGT121 allosterically modulates CD4 binding via recognition of the HIV-1 gp120 V3 base and multiple surrounding glycans.<\/a><\/span><\/p>\n<div class=\"supp\">\n<p class=\"desc\">Julien JP, Sok D, Khayat R, Lee JH, Doores KJ, Walker LM, Ramos A, Diwanji DC, Pejchal R, Cupo A, Katpally U, Depetris RS, Stanfield RL, McBride R, Marozsan AJ, Paulson JC, Sanders RW, Moore JP, Burton DR, Poignard P, Ward AB, Wilson IA.<\/p>\n<p class=\"details\"><em><span class=\"jrnl\" title=\"PLoS pathogens\">PLoS Pathog<\/span><\/em>. 2013;9(5):e1003342. doi: 10.1371\/journal.ppat.1003342. Epub 2013 May 2.\u00a0PMID:23658524<\/p>\n<p class=\"details\">\n<\/div>\n<\/div>\n<\/div>\n<div class=\"rprt\">\n<div class=\"rslt\">\n<p class=\"title\"><span style=\"color: #000080\"><a style=\"color: #000080\" href=\"http:\/\/www.ncbi.nlm.nih.gov\/pubmed\/23539181\">Rational HIV immunogen design to target specific germline B cell receptors.<\/a><\/span><\/p>\n<div class=\"supp\">\n<p class=\"desc\">Jardine J, Julien JP, Menis S, Ota T, Kalyuzhniy O, McGuire A, Sok D, Huang PS, MacPherson S, Jones M, Nieusma T, Mathison J, Baker D, Ward AB, Burton DR, Stamatatos L, Nemazee D, Wilson IA, Schief WR.<\/p>\n<p class=\"details\"><em><span class=\"jrnl\" title=\"Science (New York, N.Y.)\">Science<\/span><\/em>. 2013 May 10;340(6133):711-6. doi: 10.1126\/science.1234150. Epub 2013 Mar 28.\u00a0PMID:23539181<\/p>\n<p class=\"details\">\n<\/div>\n<\/div>\n<\/div>\n<div class=\"rprt\">\n<div class=\"rslt\">\n<p class=\"title\"><span style=\"color: #000080\"><a style=\"color: #000080\" href=\"http:\/\/www.ncbi.nlm.nih.gov\/pubmed\/23426631\">Asymmetric recognition of the HIV-1 trimer by broadly neutralizing antibody PG9.<\/a><\/span><\/p>\n<div class=\"supp\">\n<p class=\"desc\">Julien JP, Lee JH, Cupo A, Murin CD, Derking R, Hoffenberg S, Caulfield MJ, King CR, Marozsan AJ, Klasse PJ, Sanders RW, Moore JP, Wilson IA, Ward AB.<\/p>\n<p class=\"details\"><em><span class=\"jrnl\" title=\"Proceedings of the National Academy of Sciences of the United States of America\">Proc Natl Acad Sci U S A<\/span><\/em>. 2013 Mar 12;110(11):4351-6. doi: 10.1073\/pnas.1217537110. Epub 2013 Feb 20.\u00a0PMID:23426631<\/p>\n<p class=\"details\">\n<\/div>\n<\/div>\n<\/div>\n<\/div>\n<\/div>\n<\/div>\n<\/div>\n<\/div><div class=\"nav fusion-mobile-tab-nav\"><ul class=\"nav-tabs\" role=\"tablist\"><li role=\"presentation\"><a class=\"tab-link\" data-toggle=\"tab\" role=\"tab\" aria-controls=\"tab-047d121a944f94414b2\" aria-selected=\"false\" tabindex=\"-1\" id=\"mobile-fusion-tab-2012\" href=\"#tab-047d121a944f94414b2\"><h4 class=\"fusion-tab-heading\">2012<\/h4><\/a><\/li><\/ul><\/div><div class=\"tab-pane fade fusion-clearfix\" role=\"tabpanel\" tabindex=\"0\" aria-labelledby=\"fusion-tab-2012\" id=\"tab-047d121a944f94414b2\">\n<div class=\"rprt\">\n<div class=\"rslt\">\n<p class=\"title\"><a href=\"http:\/\/www.ncbi.nlm.nih.gov\/pubmed\/23046130\"><span style=\"color: #000080\">Structural insights into key sites of vulnerability on HIV-1 Env and influenza HA<\/span>.<\/a><\/p>\n<div class=\"supp\">\n<p class=\"desc\">Julien JP, Lee PS, Wilson IA.<\/p>\n<p class=\"details\"><em><span class=\"jrnl\" title=\"Immunological reviews\">Immunol Rev<\/span><\/em>. 2012 Nov;250(1):180-98. doi: 10.1111\/imr.12005. Review.\u00a0PMID:23046130<\/p>\n<p class=\"details\">\n<\/div>\n<\/div>\n<\/div>\n<div class=\"rprt\">\n<div class=\"rslt\">\n<p class=\"title\"><span style=\"color: #000080\"><a style=\"color: #000080\" href=\"http:\/\/www.ncbi.nlm.nih.gov\/pubmed\/23028316\">Marburg virus VP35 can both fully coat the backbone and cap the ends of dsRNA for interferon antagonism.<\/a><\/span><\/p>\n<div class=\"supp\">\n<p class=\"desc\">Bale S, Julien JP, Bornholdt ZA, Kimberlin CR, Halfmann P, Zandonatti MA, Kunert J, Kroon GJ, Kawaoka Y, MacRae IJ, Wilson IA, Saphire EO.<\/p>\n<p class=\"details\"><em><span class=\"jrnl\" title=\"PLoS pathogens\">PLoS Pathog<\/span><\/em>. 2012 Sep;8(9):e1002916. doi: 10.1371\/journal.ppat.1002916. Epub 2012 Sep 13.\u00a0PMID:23028316<\/p>\n<p class=\"details\">\n<\/div>\n<\/div>\n<\/div>\n<div class=\"rprt\">\n<div class=\"rslt\">\n<p class=\"title\"><span style=\"color: #000080\"><a style=\"color: #000080\" href=\"http:\/\/www.ncbi.nlm.nih.gov\/pubmed\/22645128\">Partial enzymatic deglycosylation preserves the structure of cleaved recombinant HIV-1 envelope glycoprotein trimers.<\/a><\/span><\/p>\n<div class=\"supp\">\n<p class=\"desc\">Depetris RS, Julien JP, Khayat R, Lee JH, Pejchal R, Katpally U, Cocco N, Kachare M, Massi E, David KB, Cupo A, Marozsan AJ, Olson WC, Ward AB, Wilson IA, Sanders RW, Moore JP.<\/p>\n<p class=\"details\"><em><span class=\"jrnl\" title=\"The Journal of biological chemistry\">J Biol Chem<\/span><\/em>. 2012 Jul 13;287(29):24239-54. doi: 10.1074\/jbc.M112.371898. Epub 2012 May 29.\u00a0PMID:22645128<\/p>\n<p class=\"details\">\n<\/div>\n<\/div>\n<\/div>\n<div class=\"rprt\">\n<div class=\"rslt\">\n<p class=\"title\"><span style=\"color: #000080\"><a style=\"color: #000080\" href=\"http:\/\/www.ncbi.nlm.nih.gov\/pubmed\/22238313\">Neutralizing epitopes in the membrane-proximal external region of HIV-1 gp41 are influenced by the transmembrane domain and the plasma membrane.<\/a><\/span><\/p>\n<div class=\"supp\">\n<p class=\"desc\">Montero M, Gulzar N, Klaric KA, Donald JE, Lepik C, Wu S, Tsai S, Julien JP, Hessell AJ, Wang S, Lu S, Burton DR, Pai EF, Degrado WF, Scott JK.<\/p>\n<p class=\"details\"><em><span class=\"jrnl\" title=\"Journal of virology\">J Virol<\/span><\/em>. 2012 Mar;86(6):2930-41. doi: 10.1128\/JVI.06349-11. Epub 2012 Jan 11.\u00a0PMID:22238313<\/p>\n<p class=\"details\">\n<\/div>\n<div class=\"aux\">\n<div class=\"resc\">\n<p class=\"title\"><span style=\"color: #000080\"><a style=\"color: #000080\" href=\"http:\/\/www.ncbi.nlm.nih.gov\/pubmed\/22061265\">Computational design of high-affinity epitope scaffolds by backbone grafting of a linear epitope.<\/a><\/span><\/p>\n<div class=\"supp\">\n<p class=\"desc\">Azoitei ML, Ban YE, Julien JP, Bryson S, Schroeter A, Kalyuzhniy O, Porter JR, Adachi Y, Baker D, Pai EF, Schief WR.<\/p>\n<p class=\"details\"><em><span class=\"jrnl\" title=\"Journal of molecular biology\">J Mol Biol<\/span><\/em>. 2012 Jan 6;415(1):175-92. doi: 10.1016\/j.jmb.2011.10.003. Epub 2011 Oct 31.\u00a0PMID:22061265<\/p>\n<p class=\"details\">\n<\/div>\n<\/div>\n<\/div>\n<\/div>\n<\/div>\n<\/div><div class=\"nav fusion-mobile-tab-nav\"><ul class=\"nav-tabs\" role=\"tablist\"><li role=\"presentation\"><a class=\"tab-link\" data-toggle=\"tab\" role=\"tab\" aria-controls=\"tab-86acae89c9cc02b38c5\" aria-selected=\"false\" tabindex=\"-1\" id=\"mobile-fusion-tab-2011\" href=\"#tab-86acae89c9cc02b38c5\"><h4 class=\"fusion-tab-heading\">2011<\/h4><\/a><\/li><\/ul><\/div><div class=\"tab-pane fade fusion-clearfix\" role=\"tabpanel\" tabindex=\"0\" aria-labelledby=\"fusion-tab-2011\" id=\"tab-86acae89c9cc02b38c5\">\n<div class=\"rprt\">\n<div class=\"rslt\">\n<p class=\"title\"><span style=\"color: #000080\"><a style=\"color: #000080\" href=\"http:\/\/www.ncbi.nlm.nih.gov\/pubmed\/22033480\">Structure-based design of a protein immunogen that displays an HIV-1 gp41 neutralizing epitope.<\/a><\/span><\/p>\n<div class=\"supp\">\n<p class=\"desc\">Stanfield RL, Julien JP, Pejchal R, Gach JS, Zwick MB, Wilson IA.<\/p>\n<p class=\"details\"><em><span class=\"jrnl\" title=\"Journal of molecular biology\">J Mol Biol<\/span><\/em>. 2011 Dec 2;414(3):460-76. doi: 10.1016\/j.jmb.2011.10.014. Epub 2011 Oct 15.\u00a0PMID:22033480<\/p>\n<p class=\"details\">\n<\/div>\n<\/div>\n<\/div>\n<div class=\"rprt\">\n<div class=\"rslt\">\n<p class=\"title\"><span style=\"color: #000080\"><a style=\"color: #000080\" href=\"http:\/\/www.ncbi.nlm.nih.gov\/pubmed\/21998254\">A potent and broad neutralizing antibody recognizes and penetrates the HIV glycan shield.<\/a><\/span><\/p>\n<div class=\"supp\">\n<p class=\"desc\">Pejchal R, Doores KJ, Walker LM, Khayat R, Huang PS, Wang SK, Stanfield RL, Julien JP, Ramos A, Crispin M, Depetris R, Katpally U, Marozsan A, Cupo A, Maloveste S, Liu Y, McBride R, Ito Y, Sanders RW, Ogohara C, Paulson JC, Feizi T, Scanlan CN, Wong CH, Moore JP, Olson WC, Ward AB, Poignard P, Schief WR, Burton DR, Wilson IA.<\/p>\n<p class=\"details\"><em><span class=\"jrnl\" title=\"Science (New York, N.Y.)\">Science<\/span><\/em>. 2011 Nov 25;334(6059):1097-103. doi: 10.1126\/science.1213256. Epub 2011 Oct 13.\u00a0PMID:21998254<\/p>\n<p class=\"details\">\n<\/div>\n<\/div>\n<\/div>\n<div class=\"rprt\">\n<div class=\"rslt\">\n<p class=\"title\"><span style=\"color: #000080\"><a style=\"color: #000080\" href=\"http:\/\/www.ncbi.nlm.nih.gov\/pubmed\/21849977\">Broad neutralization coverage of HIV by multiple highly potent antibodies.<\/a><\/span><\/p>\n<div class=\"supp\">\n<p class=\"desc\">Walker LM, Huber M, Doores KJ, Falkowska E, Pejchal R, Julien JP, Wang SK, Ramos A, Chan-Hui PY, Moyle M, Mitcham JL, Hammond PW, Olsen OA, Phung P, Fling S, Wong CH, Phogat S, Wrin T, Simek MD; Protocol G Principal Investigators, Koff WC, Wilson IA, Burton DR, Poignard P.<\/p>\n<p class=\"details\"><em><span class=\"jrnl\" title=\"Nature\">Nature<\/span><\/em>. 2011 Sep 22;477(7365):466-70. doi: 10.1038\/nature10373.\u00a0PMID:21849977<\/p>\n<p class=\"details\">\n<\/div>\n<\/div>\n<\/div>\n<div class=\"rprt\">\n<div class=\"rslt\">\n<p class=\"title\"><span style=\"color: #000080\"><a style=\"color: #000080\" href=\"http:\/\/www.ncbi.nlm.nih.gov\/pubmed\/21142698\">Interaction of anti-HIV type 1 antibody 2F5 with phospholipid bilayers and its relevance for the mechanism of virus neutralization.<\/a><\/span><\/p>\n<div class=\"supp\">\n<p class=\"desc\"><span style=\"color: #808080\">Maeso R, Huarte N, Julien JP, Kunert R, Pai EF, Nieva JL.<\/span><\/p>\n<p class=\"details\"><span style=\"color: #808080\"><em><span class=\"jrnl\" title=\"AIDS research and human retroviruses\">AIDS Res Hum Retroviruses<\/span><\/em>. 2011 Aug;27(8):863-76. doi: 10.1089\/AID.2010.0265. Epub 2011 Jan 15.\u00a0PMID:21142698<\/span><\/p>\n<\/div>\n<\/div>\n<\/div>\n<\/div><div class=\"nav fusion-mobile-tab-nav\"><ul class=\"nav-tabs\" role=\"tablist\"><li role=\"presentation\"><a class=\"tab-link\" data-toggle=\"tab\" role=\"tab\" aria-controls=\"tab-cac579999c4eefd178a\" aria-selected=\"false\" tabindex=\"-1\" id=\"mobile-fusion-tab-2010\" href=\"#tab-cac579999c4eefd178a\"><h4 class=\"fusion-tab-heading\">2010<\/h4><\/a><\/li><\/ul><\/div><div class=\"tab-pane fade fusion-clearfix\" role=\"tabpanel\" tabindex=\"0\" aria-labelledby=\"fusion-tab-2010\" id=\"tab-cac579999c4eefd178a\">\n<div class=\"rprtnum nohighlight\">\n<p><a style=\"color: #000080\" href=\"http:\/\/www.ncbi.nlm.nih.gov\/pubmed\/20147404\">Ablation of the complementarity-determining region H3 apex of the anti-HIV-1 broadly neutralizing antibody 2F5 abrogates neutralizing capacity without affecting core epitope binding.<\/a><\/p>\n<div class=\"rslt\">\n<div class=\"supp\">\n<p class=\"desc\">Julien JP, Huarte N, Maeso R, Taneva SG, Cunningham A, Nieva JL, Pai EF.<\/p>\n<p class=\"details\"><em><span class=\"jrnl\" title=\"Journal of virology\">J Virol<\/span><\/em>. 2010 May;84(9):4136-47. doi: 10.1128\/JVI.02357-09. Epub 2010 Feb 10.\u00a0PMID:20147404<\/p>\n<\/div>\n<\/div>\n<\/div>\n<\/div><div class=\"nav fusion-mobile-tab-nav\"><ul class=\"nav-tabs\" role=\"tablist\"><li role=\"presentation\"><a class=\"tab-link\" data-toggle=\"tab\" role=\"tab\" aria-controls=\"tab-47581cc8595ecdb1fd1\" aria-selected=\"false\" tabindex=\"-1\" id=\"mobile-fusion-tab-2009\" href=\"#tab-47581cc8595ecdb1fd1\"><h4 class=\"fusion-tab-heading\">2009<\/h4><\/a><\/li><\/ul><\/div><div class=\"tab-pane fade fusion-clearfix\" role=\"tabpanel\" tabindex=\"0\" aria-labelledby=\"fusion-tab-2009\" id=\"tab-47581cc8595ecdb1fd1\">\n<p class=\"title\"><span style=\"color: #000080\"><a style=\"color: #000080\" href=\"http:\/\/www.ncbi.nlm.nih.gov\/pubmed\/19754136\">Structural constraints imposed by the conserved fusion peptide on the HIV-1 gp41 epitope recognized by the broadly neutralizing antibody 2F5.<\/a><\/span><\/p>\n<div class=\"supp\">\n<p class=\"desc\">de la Arada I, Julien JP, de la Torre BG, Huarte N, Andreu D, Pai EF, Arrondo JL, Nieva JL.<\/p>\n<p class=\"details\"><em><span class=\"jrnl\" title=\"The journal of physical chemistry. B\">J Phys Chem B<\/span><\/em>. 2009 Oct 15;113(41):13626-37. doi: 10.1021\/jp905965h.\u00a0PMID:19754136<\/p>\n<p class=\"details\">\n<\/div>\n<div class=\"aux\">\n<div class=\"resc\">\n<p class=\"title\"><span style=\"color: #000080\"><a style=\"color: #000080\" href=\"http:\/\/www.ncbi.nlm.nih.gov\/pubmed\/19740978\">Crystallographic definition of the epitope promiscuity of the broadly neutralizing anti-human immunodeficiency virus type 1 antibody 2F5: vaccine design implications.<\/a><\/span><\/p>\n<div class=\"supp\">\n<p class=\"desc\">Bryson S, Julien JP, Hynes RC, Pai EF.<\/p>\n<p class=\"details\"><em><span class=\"jrnl\" title=\"Journal of virology\">J Virol<\/span><\/em>. 2009 Nov;83(22):11862-75. doi: 10.1128\/JVI.01604-09. Epub 2009 Sep 9.\u00a0PMID:19740978<\/p>\n<p class=\"details\">\n<\/div>\n<\/div>\n<\/div>\n<\/div><div class=\"nav fusion-mobile-tab-nav\"><ul class=\"nav-tabs\" role=\"tablist\"><li role=\"presentation\"><a class=\"tab-link\" data-toggle=\"tab\" role=\"tab\" aria-controls=\"tab-523b2dcbe2155e07ab5\" aria-selected=\"false\" tabindex=\"-1\" id=\"mobile-fusion-tab-2008\" href=\"#tab-523b2dcbe2155e07ab5\"><h4 class=\"fusion-tab-heading\">2008<\/h4><\/a><\/li><\/ul><\/div><div class=\"tab-pane fade fusion-clearfix\" role=\"tabpanel\" tabindex=\"0\" aria-labelledby=\"fusion-tab-2008\" id=\"tab-523b2dcbe2155e07ab5\">\n<div class=\"rprt\">\n<div class=\"rprtnum nohighlight\">\n<p><a style=\"color: #000080\" href=\"http:\/\/www.ncbi.nlm.nih.gov\/pubmed\/18824005\">Structural details of HIV-1 recognition by the broadly neutralizing monoclonal antibody 2F5: epitope conformation, antigen-recognition loop mobility, and anion-binding site.<\/a><\/p>\n<div class=\"rslt\">\n<div class=\"supp\">\n<p class=\"desc\">Julien JP, Bryson S, Nieva JL, Pai EF.<\/p>\n<p class=\"details\"><em><span class=\"jrnl\" title=\"Journal of molecular biology\">J Mol Biol<\/span><\/em>. 2008 Dec 12;384(2):377-92. doi: 10.1016\/j.jmb.2008.09.024. Epub 2008 Sep 18.\u00a0PMID:18824005<\/p>\n<\/div>\n<div class=\"aux\"><\/div>\n<\/div>\n<\/div>\n<div class=\"rprt\">\n<div class=\"rslt\">\n<p class=\"title\"><span style=\"color: #000080\"><a style=\"color: #000080\" href=\"http:\/\/www.ncbi.nlm.nih.gov\/pubmed\/18692506\">Crystal structure of the complex between the F(ab)&#8217; fragment of the cross-neutralizing anti-HIV-1 antibody 2F5 and the F(ab) fragment of its anti-idiotypic antibody 3H6.<\/a><\/span><\/p>\n<div class=\"supp\">\n<p class=\"desc\">Bryson S, Julien JP, Isenman DE, Kunert R, Katinger H, Pai EF.<\/p>\n<p class=\"details\"><em><span class=\"jrnl\" title=\"Journal of molecular biology\">J Mol Biol<\/span><\/em>. 2008 Oct 17;382(4):910-9. doi: 10.1016\/j.jmb.2008.07.057. Epub 2008 Jul 27.\u00a0PMID:18692506<\/p>\n<\/div>\n<\/div>\n<\/div>\n<\/div>\n<\/div><div class=\"nav fusion-mobile-tab-nav\"><ul class=\"nav-tabs\" role=\"tablist\"><li role=\"presentation\"><a class=\"tab-link\" data-toggle=\"tab\" role=\"tab\" aria-controls=\"tab-5afda7eccd42c3defe3\" aria-selected=\"false\" tabindex=\"-1\" id=\"mobile-fusion-tab-2006\" href=\"#tab-5afda7eccd42c3defe3\"><h4 class=\"fusion-tab-heading\">2006<\/h4><\/a><\/li><\/ul><\/div><div class=\"tab-pane fade fusion-clearfix\" role=\"tabpanel\" tabindex=\"0\" aria-labelledby=\"fusion-tab-2006\" id=\"tab-5afda7eccd42c3defe3\">\n<p class=\"title\"><span style=\"color: #000080\"><a style=\"color: #000080\" href=\"http:\/\/www.ncbi.nlm.nih.gov\/pubmed\/16421095\">Structural and functional characterization of PseC, an aminotransferase involved in the biosynthesis of pseudaminic acid, an essential flagellar modification in Helicobacter pylori.<\/a><\/span><\/p>\n<div class=\"supp\">\n<p class=\"desc\">Schoenhofen IC, Lunin VV, Julien JP, Li Y, Ajamian E, Matte A, Cygler M, Brisson JR, Aubry A, Logan SM, Bhatia S, Wakarchuk WW, Young NM.<\/p>\n<p class=\"details\"><em><span class=\"jrnl\" title=\"The Journal of biological chemistry\">J Biol Chem<\/span><\/em>. 2006 Mar 31;281(13):8907-16. Epub 2006 Jan 18.\u00a0PMID:16421095<\/p>\n<\/div>\n<\/div><\/div><\/div><div class=\"fusion-clearfix\"><\/div><\/div><\/div><\/div><\/div>\n","protected":false},"excerpt":{"rendered":"","protected":false},"author":44,"featured_media":0,"parent":0,"menu_order":0,"comment_status":"closed","ping_status":"closed","template":"","meta":{"footnotes":""},"class_list":["post-17","page","type-page","status-publish","hentry"],"yoast_head":"<!-- This site is optimized with the Yoast SEO Premium plugin v27.0 (Yoast SEO v27.0) - https:\/\/yoast.com\/product\/yoast-seo-premium-wordpress\/ -->\n<title>Publications - Julien Lab<\/title>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/lab.research.sickkids.ca\/julien\/publications\/\" \/>\n<meta property=\"og:locale\" content=\"en_US\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"Publications\" \/>\n<meta property=\"og:url\" content=\"https:\/\/lab.research.sickkids.ca\/julien\/publications\/\" \/>\n<meta property=\"og:site_name\" content=\"Julien Lab\" \/>\n<meta property=\"article:modified_time\" content=\"2026-02-01T14:50:37+00:00\" \/>\n<meta property=\"og:image\" content=\"https:\/\/lab.research.sickkids.ca\/julien\/wp-content\/uploads\/sites\/24\/2019\/12\/cover-image.png\" \/>\n\t<meta property=\"og:image:width\" content=\"300\" \/>\n\t<meta property=\"og:image:height\" content=\"414\" \/>\n\t<meta property=\"og:image:type\" content=\"image\/png\" \/>\n<meta name=\"twitter:card\" content=\"summary_large_image\" \/>\n<meta name=\"twitter:label1\" content=\"Est. reading time\" \/>\n\t<meta name=\"twitter:data1\" content=\"29 minutes\" \/>\n<script type=\"application\/ld+json\" class=\"yoast-schema-graph\">{\"@context\":\"https:\/\/schema.org\",\"@graph\":[{\"@type\":\"WebPage\",\"@id\":\"https:\/\/lab.research.sickkids.ca\/julien\/publications\/\",\"url\":\"https:\/\/lab.research.sickkids.ca\/julien\/publications\/\",\"name\":\"Publications - 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