{"id":207,"date":"2021-06-04T05:33:16","date_gmt":"2021-06-04T05:33:16","guid":{"rendered":"https:\/\/lab.research.sickkids.ca\/jones\/?page_id=207"},"modified":"2021-09-27T13:21:55","modified_gmt":"2021-09-27T13:21:55","slug":"publications","status":"publish","type":"page","link":"https:\/\/lab.research.sickkids.ca\/jones\/publications\/","title":{"rendered":"Publications"},"content":{"rendered":"<div class=\"wpb-content-wrapper\"><p>[vc_row][vc_column][vc_column_text css_animation=&#8221;fadeIn&#8221; css=&#8221;.vc_custom_1632748896351{margin-top: 3px !important;margin-right: 3px !important;margin-bottom: 3px !important;margin-left: 3px !important;border-top-width: 2px !important;border-right-width: 2px !important;border-bottom-width: 2px !important;border-left-width: 2px !important;padding-top: 1px !important;padding-right: 1px !important;padding-bottom: 1px !important;padding-left: 1px !important;border-left-color: #ffffff !important;border-left-style: none !important;border-right-color: #ffffff !important;border-right-style: none !important;border-top-color: #ffffff !important;border-top-style: none !important;border-bottom-color: #ffffff !important;border-bottom-style: none !important;}&#8221;][vc_row][vc_column width=&#8221;1\/1&#8243;][vc_column_text]<\/p>\n<h2>Highlighted Publications<\/h2>\n<div class=\"hr-thick\"><\/div>\n<ul>\n<li>McGillis L, Bronte-Tinkew, D, Dang F, McGillis L, Capurro M, Greenfield L, Riccuito A, Lozano-Ruf A, Siddiqui I, Hsieh A, Church P, Walters T, Roth D, Griffiths A, Philpott D, <strong>Jones NL<\/strong>. <a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/34159811\/\" target=\"_blank\" rel=\"noopener\">Vitamin D deficiency enhances expression of autophagy-regulating miR-142-3p in mouse and inflamed IBD patient intestinal tissues<\/a>. American Journal of Physiology GI. 2021 Aug 1;321(2): G171-G184.<\/li>\n<li>Capurro MI, Prashar A, <strong>Jones NL<\/strong>. <a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/31599196\/\" target=\"_blank\" rel=\"noopener\">MCOLN1\/TRPML1 inhibition &#8211; a novel strategy used by Helicobacter pylori to escape autophagic killing and antibiotic eradication therapy in vivo<\/a>. Autophagy. 2020 Jan;16(1):169-170.<\/li>\n<li>Capurro M, Greenfield LK, Abdullah M, Wong H, Zhong XZ, Wilms KJD, Bertaux-Skeirik N, Chakrabarti J, O\u2019Brien C, Dong XP, Robinson L, Philpott DJ, Zavros Y, Helmrath M, <strong>Jones NL<\/strong>. (2019). <a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/31110360\/\" target=\"_blank\" rel=\"noopener\">VacA generates a protective intracellular reservoir for Helicobacter pylori which is eliminated by activation of the lysosomal calcium channel TRPML1<\/a>. Nature Microbiology. 4(8): 1411-1423.<\/li>\n<li>Abdullah M, Greenfield L, Bronte-Tinkew D, Capurro M, Rizzuti D, <strong>Jones NL<\/strong>. (2019). <a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/30631092\/\" target=\"_blank\" rel=\"noopener\">VacA promotes CagA accumulation in gastric epithelial cells during Helicobacter pylori infection<\/a>. Scientific Reports. 9(1): 38<\/li>\n<li>Sibony M, Abdullah M, Greenfield L, Raju D, Wu T, Rodrigues D, Galindo-Mata E, Mascarenhas H, Philpott D, Silverberg M, <strong>Jones NL<\/strong>. <a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/26332312\/\" target=\"_blank\" rel=\"noopener\">Microbial disruption of autophagy alters expression of the RISC component AGO2, a critical regulator of the miRNA silencing pathway<\/a>. Journal of Inflammatory Bowel Diseases Dec 2015: 21 (12): pp 2778-2786. PMID: 26332312<\/li>\n<li>Rizzuti D, Ang M, Sokollik C, Wu T, Fattouh R, Reardon C, Schindler C, <strong>Jones NL<\/strong>. <a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/25412627\/\" target=\"_blank\" rel=\"noopener\">Helicobacter pylori inhibits dendritic cell maturation via interleukin-10 mediated activation of the signal transducer and activator of transcription 3 (STAT3) pathway<\/a>. Journal of Innate Immunity Feb 2015: 7 (2): pp 199-211. PMID: 25412627<\/li>\n<li>Raju D, Hussey S, Ang M, Terebiznik MR, Sibony M, Galindo-Mata E, Gupta V, Blanke SR, Delgado A, Romero-Gallo J, Ramjeet MS, Mascarenhas H, Peek RM, Correa P, Streutker C, Hold G, Kunstmann E, Yoshimori T, Silverberg MS, Girardin SE, Philpott DJ, El Omar E, <strong>Jones NL<\/strong>. <a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/22333951\/\" target=\"_blank\" rel=\"noopener\">Vacuolating cytotoxin and variants in Atg16L1 that disrupt autophagy promote Helicobacter pylori infection in humans<\/a>. Gastroenterology 2012: 142 (5): pp 1160-1171.<\/li>\n<li>Travasso LH, Carneiro LAM, Hussey S, Yuan L, Magalhaes JG, Le Bourhis L, Ramjeet M, Boneca IG, Allaoui A, <strong>Jones NL<\/strong>, Girardin SE and Philpott DJ. <a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/19898471\/\" target=\"_blank\" rel=\"noopener\">Nod1 and Nod2 direct autophagy by recruiting ATG16L1 to the plasma membrane at the site of bacterial entry.<\/a> Nature Immunology. 2010: 11 (1): pp 55-62. (Accompanying editorial in Nature Medicine 2010: 16 (1): pp 28-30).<\/li>\n<\/ul>\n<p>&nbsp;<\/p>\n<h2>2021<\/h2>\n<div class=\"hr-thick\"><\/div>\n<ul>\n<li>McGillis L, Bronte-Tinkew, D, Dang F, McGillis L, Capurro M, Greenfield L, Riccuito A, Lozano-Ruf A, Siddiqui I, Hsieh A, Church P, Walters T, Roth D, Griffiths A, Philpott D, <strong>Jones NL<\/strong>. Vitamin D deficiency enhances expression of autophagy-regulating miR-142-3p in mouse and inflamed IBD patient intestinal tissues. American Journal of Physiology GI. 2021 Aug 1;321(2): G171-G184.<\/li>\n<li>Macarthur C, Walsh C, Buchanan F, Karoly A, Pires L, McCreath G, <strong>Jones NL<\/strong>. Development of the Patient-Oriented Research Curriculum in Child Health (PORCCH). Submitted to Research Involvement and Engagement. <em>Accepted<\/em><\/li>\n<li>Prashar A, Capurro MI, <strong>Jones NL<\/strong>. (2021). Under the radar: Strategies used by <em>Helicobacter pylori<\/em> to evade host responses. Annual Reviews in Physiology. <em>Accepted<\/em><\/li>\n<li>Jaehoon C, Prashar A, <strong>Jones N<\/strong>, Moss, SF. (2021). <em>Helicobacter pylori<\/em> Infection. Gastroenterology Clinics of NA. 50(2): 1131.<\/li>\n<\/ul>\n<h2><\/h2>\n<h2>2020<\/h2>\n<div class=\"hr-thick\"><\/div>\n<ul>\n<li>Seo JH, Bortolin K, Jones NL. (2020). Review: <em>Helicobacter pylori<\/em> infection in Children. Helicobacter. 25(S1): e12742<\/li>\n<li>Capurro MI, Prashar A, <strong>Jones NL<\/strong>. MCOLN1\/TRPML1 inhibition &#8211; a novel strategy used by Helicobacter pylori to escape autophagic killing and antibiotic eradication therapy in vivo. Autophagy. 2020 Jan;16(1):169-170<\/li>\n<\/ul>\n<p>&nbsp;<\/p>\n<h2>2019<\/h2>\n<div class=\"hr-thick\"><\/div>\n<ul>\n<li>Capurro M, Greenfield LK, Abdullah M, Wong H, Zhong XZ, Wilms KJD, Bertaux-Skeirik N, Chakrabarti J, O\u2019Brien C, Dong XP, Robinson L, Philpott DJ, Zavros Y, Helmrath M, <strong>Jones NL<\/strong>. (2019). VacA generates a protective intracellular reservoir for Helicobacter pylori which is eliminated by activation of the lysosomal calcium channel TRPML1. Nature Microbiology. 4(8): 1411-1423.<\/li>\n<li>Abdullah M, Greenfield L, Bronte-Tinkew D, Capurro M, Rizzuti D, <strong>Jones NL<\/strong>. (2019). VacA promotes CagA accumulation in gastric epithelial cells during Helicobacter pylori infection. Scientific Reports. 9(1): 38<\/li>\n<li>Goldaracena N, Echeverri J, Kehar M, DeAngelis M, <strong>Jones N<\/strong>, Ling S, Kamath BM, Avitzur Y, Ng VL, Cattral MS, Grant DR, Ghanekar A. (2019). Pediatric Living Donor Liver Transplantation with Large-for-Size Left Lateral Segment Grafts. Am J Transplant. 20(2):504-512<\/li>\n<li>\u00a0Benchimol E, <strong>Jones NL<\/strong>, Muise AM, Sherman PM. (2019). 2019 Harry Shwachman Award: Dr. Anne M. Griffiths, MD, FRCPC. J Pediatric Gastroenterology Nutrition.<\/li>\n<li>Kehar M, Parekh R.S, Stunguris J, De Angelis M, Van Roestel K, Ghanekar A, Cattral M, Fecteau A, Ling S, Kamath BM, <strong>Jones N<\/strong>, Avitzur Y, Grant D, NG VL. Superior outcomes and reduced wait times in pediatric recipients of living donor liver transplantation. Transplantation Direct Feb 2019: 5 (3): pp e430.<\/li>\n<\/ul>\n<p>[\/vc_column_text][\/vc_column][\/vc_row]<\/p>\n<\/div>","protected":false},"excerpt":{"rendered":"<p>[vc_row][vc_column][vc_column_text css_animation=&#8221;fadeIn&#8221; css=&#8221;.vc_custom_1632748896351{margin-top: 3px !important;margin-right: 3px !important;margin-bottom: 3px !important;margin-left: 3px !important;border-top-width: 2px !important;border-right-width: 2px !important;border-bottom-width: 2px !important;border-left-width: 2px !important;padding-top: 1px !important;padding-right: 1px !important;padding-bottom: 1px !important;padding-left: 1px !important;border-left-color: #ffffff !important;border-left-style: none !important;border-right-color: #ffffff !important;border-right-style: none !important;border-top-color: #ffffff !important;border-top-style: none !important;border-bottom-color: #ffffff !important;border-bottom-style: none !important;}&#8221;][vc_row][vc_column width=&#8221;1\/1&#8243;][vc_column_text] Highlighted Publications McGillis L, Bronte-Tinkew, D, Dang F, McGillis L, Capurro&hellip;<\/p>\n","protected":false},"author":332,"featured_media":0,"parent":0,"menu_order":0,"comment_status":"closed","ping_status":"closed","template":"","meta":{"footnotes":""},"class_list":["post-207","page","type-page","status-publish","hentry","description-off"],"yoast_head":"<!-- This site is optimized with the Yoast SEO Premium plugin v27.0 (Yoast SEO v27.0) - https:\/\/yoast.com\/product\/yoast-seo-premium-wordpress\/ -->\n<title>Publications - Jones Lab<\/title>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/lab.research.sickkids.ca\/jones\/publications\/\" \/>\n<meta property=\"og:locale\" content=\"en_US\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"Publications\" \/>\n<meta property=\"og:description\" content=\"[vc_row][vc_column][vc_column_text css_animation=&#8221;fadeIn&#8221; css=&#8221;.vc_custom_1632748896351{margin-top: 3px !important;margin-right: 3px !important;margin-bottom: 3px !important;margin-left: 3px !important;border-top-width: 2px !important;border-right-width: 2px !important;border-bottom-width: 2px !important;border-left-width: 2px !important;padding-top: 1px !important;padding-right: 1px !important;padding-bottom: 1px !important;padding-left: 1px !important;border-left-color: #ffffff !important;border-left-style: none !important;border-right-color: #ffffff !important;border-right-style: none !important;border-top-color: #ffffff !important;border-top-style: none !important;border-bottom-color: #ffffff !important;border-bottom-style: none !important;}&#8221;][vc_row][vc_column width=&#8221;1\/1&#8243;][vc_column_text] Highlighted Publications McGillis L, Bronte-Tinkew, D, Dang F, McGillis L, Capurro&hellip;\" \/>\n<meta property=\"og:url\" content=\"https:\/\/lab.research.sickkids.ca\/jones\/publications\/\" \/>\n<meta property=\"og:site_name\" content=\"Jones Lab\" \/>\n<meta property=\"article:modified_time\" content=\"2021-09-27T13:21:55+00:00\" \/>\n<meta name=\"twitter:card\" content=\"summary_large_image\" \/>\n<meta name=\"twitter:label1\" content=\"Est. reading time\" \/>\n\t<meta name=\"twitter:data1\" content=\"4 minutes\" \/>\n<script type=\"application\/ld+json\" class=\"yoast-schema-graph\">{\"@context\":\"https:\/\/schema.org\",\"@graph\":[{\"@type\":\"WebPage\",\"@id\":\"https:\/\/lab.research.sickkids.ca\/jones\/publications\/\",\"url\":\"https:\/\/lab.research.sickkids.ca\/jones\/publications\/\",\"name\":\"Publications - Jones Lab\",\"isPartOf\":{\"@id\":\"https:\/\/lab.research.sickkids.ca\/jones\/#website\"},\"datePublished\":\"2021-06-04T05:33:16+00:00\",\"dateModified\":\"2021-09-27T13:21:55+00:00\",\"breadcrumb\":{\"@id\":\"https:\/\/lab.research.sickkids.ca\/jones\/publications\/#breadcrumb\"},\"inLanguage\":\"en-US\",\"potentialAction\":[{\"@type\":\"ReadAction\",\"target\":[\"https:\/\/lab.research.sickkids.ca\/jones\/publications\/\"]}]},{\"@type\":\"BreadcrumbList\",\"@id\":\"https:\/\/lab.research.sickkids.ca\/jones\/publications\/#breadcrumb\",\"itemListElement\":[{\"@type\":\"ListItem\",\"position\":1,\"name\":\"Home\",\"item\":\"https:\/\/lab.research.sickkids.ca\/jones\/\"},{\"@type\":\"ListItem\",\"position\":2,\"name\":\"Publications\"}]},{\"@type\":\"WebSite\",\"@id\":\"https:\/\/lab.research.sickkids.ca\/jones\/#website\",\"url\":\"https:\/\/lab.research.sickkids.ca\/jones\/\",\"name\":\"Jones Lab\",\"description\":\"\",\"potentialAction\":[{\"@type\":\"SearchAction\",\"target\":{\"@type\":\"EntryPoint\",\"urlTemplate\":\"https:\/\/lab.research.sickkids.ca\/jones\/?s={search_term_string}\"},\"query-input\":{\"@type\":\"PropertyValueSpecification\",\"valueRequired\":true,\"valueName\":\"search_term_string\"}}],\"inLanguage\":\"en-US\"}]}<\/script>\n<!-- \/ Yoast SEO Premium plugin. -->","yoast_head_json":{"title":"Publications - Jones Lab","robots":{"index":"index","follow":"follow","max-snippet":"max-snippet:-1","max-image-preview":"max-image-preview:large","max-video-preview":"max-video-preview:-1"},"canonical":"https:\/\/lab.research.sickkids.ca\/jones\/publications\/","og_locale":"en_US","og_type":"article","og_title":"Publications","og_description":"[vc_row][vc_column][vc_column_text css_animation=&#8221;fadeIn&#8221; css=&#8221;.vc_custom_1632748896351{margin-top: 3px !important;margin-right: 3px !important;margin-bottom: 3px !important;margin-left: 3px !important;border-top-width: 2px !important;border-right-width: 2px !important;border-bottom-width: 2px !important;border-left-width: 2px !important;padding-top: 1px !important;padding-right: 1px !important;padding-bottom: 1px !important;padding-left: 1px !important;border-left-color: #ffffff !important;border-left-style: none !important;border-right-color: #ffffff !important;border-right-style: none !important;border-top-color: #ffffff !important;border-top-style: none !important;border-bottom-color: #ffffff !important;border-bottom-style: none !important;}&#8221;][vc_row][vc_column width=&#8221;1\/1&#8243;][vc_column_text] Highlighted Publications McGillis L, Bronte-Tinkew, D, Dang F, McGillis L, Capurro&hellip;","og_url":"https:\/\/lab.research.sickkids.ca\/jones\/publications\/","og_site_name":"Jones Lab","article_modified_time":"2021-09-27T13:21:55+00:00","twitter_card":"summary_large_image","twitter_misc":{"Est. reading time":"4 minutes"},"schema":{"@context":"https:\/\/schema.org","@graph":[{"@type":"WebPage","@id":"https:\/\/lab.research.sickkids.ca\/jones\/publications\/","url":"https:\/\/lab.research.sickkids.ca\/jones\/publications\/","name":"Publications - Jones Lab","isPartOf":{"@id":"https:\/\/lab.research.sickkids.ca\/jones\/#website"},"datePublished":"2021-06-04T05:33:16+00:00","dateModified":"2021-09-27T13:21:55+00:00","breadcrumb":{"@id":"https:\/\/lab.research.sickkids.ca\/jones\/publications\/#breadcrumb"},"inLanguage":"en-US","potentialAction":[{"@type":"ReadAction","target":["https:\/\/lab.research.sickkids.ca\/jones\/publications\/"]}]},{"@type":"BreadcrumbList","@id":"https:\/\/lab.research.sickkids.ca\/jones\/publications\/#breadcrumb","itemListElement":[{"@type":"ListItem","position":1,"name":"Home","item":"https:\/\/lab.research.sickkids.ca\/jones\/"},{"@type":"ListItem","position":2,"name":"Publications"}]},{"@type":"WebSite","@id":"https:\/\/lab.research.sickkids.ca\/jones\/#website","url":"https:\/\/lab.research.sickkids.ca\/jones\/","name":"Jones Lab","description":"","potentialAction":[{"@type":"SearchAction","target":{"@type":"EntryPoint","urlTemplate":"https:\/\/lab.research.sickkids.ca\/jones\/?s={search_term_string}"},"query-input":{"@type":"PropertyValueSpecification","valueRequired":true,"valueName":"search_term_string"}}],"inLanguage":"en-US"}]}},"_links":{"self":[{"href":"https:\/\/lab.research.sickkids.ca\/jones\/wp-json\/wp\/v2\/pages\/207","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/lab.research.sickkids.ca\/jones\/wp-json\/wp\/v2\/pages"}],"about":[{"href":"https:\/\/lab.research.sickkids.ca\/jones\/wp-json\/wp\/v2\/types\/page"}],"author":[{"embeddable":true,"href":"https:\/\/lab.research.sickkids.ca\/jones\/wp-json\/wp\/v2\/users\/332"}],"replies":[{"embeddable":true,"href":"https:\/\/lab.research.sickkids.ca\/jones\/wp-json\/wp\/v2\/comments?post=207"}],"version-history":[{"count":2,"href":"https:\/\/lab.research.sickkids.ca\/jones\/wp-json\/wp\/v2\/pages\/207\/revisions"}],"predecessor-version":[{"id":521,"href":"https:\/\/lab.research.sickkids.ca\/jones\/wp-json\/wp\/v2\/pages\/207\/revisions\/521"}],"wp:attachment":[{"href":"https:\/\/lab.research.sickkids.ca\/jones\/wp-json\/wp\/v2\/media?parent=207"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}