{"id":6,"date":"2015-08-24T13:59:36","date_gmt":"2015-08-24T13:59:36","guid":{"rendered":"https:\/\/lab.research.sickkids.ca\/hopyan\/?page_id=6"},"modified":"2025-12-10T18:41:04","modified_gmt":"2025-12-10T18:41:04","slug":"home","status":"publish","type":"page","link":"https:\/\/lab.research.sickkids.ca\/hopyan\/","title":{"rendered":"Home"},"content":{"rendered":"

[vc_row margin_top=”20″ margin_bottom=”20″ bg_type=”image” parallax_style=”vcpb-default” bg_image_new=”443|https:\/\/lab.research.sickkids.ca\/hopyan\/wp-content\/uploads\/sites\/16\/2015\/12\/Snowflakesright-only-copy2.jpg” bg_override=”ex-full” parallax_content=”off” enable_overlay=”off” seperator_enable=”off” ult_hide_row=”off”][vc_column width=”2\/3″]

The most important feature of our approach is the highly collaborative nature of biologists, engineers, and physicists, within our lab and beyond.<\/span><\/h4>\n<\/q>[vc_empty_space height=”5px”][vc_column_text css_animation=”fadeIn” css=””]In the embryo, many organs begin life as tiny, simple buds. \u00a0They grow, change shape, and arrange multiple types of cells into complex patterns as they mature into functioning organs. \u00a0The limbs, face, and heart are examples of organs for which form determines function. \u00a0Amazing as it is, development remains quite mysterious.<\/p>\n

Embryonic mechanisms that physically shape early organs (morphogenesis) set the stage for how well they work after birth. \u00a0Therefore, studying morphogenesis is the key to understanding how birth differences arise and for designing regenerative or therapeutic strategies. \u00a0Some of the rules that govern embryonic development go awry in diseases such as cancer, so new therapeutic ideas flow from this work.<\/p>\n

Our lab is most interested in how embryonic organs are shaped during development. \u00a0We currently focus on the limb and heart and work with other labs that have an interest in the face and skull, spine, gut, and lungs. \u00a0In our lab, we discover previously unknown ways in which organs form and figure out how genes help to control their physical development.[\/vc_column_text][vc_empty_space height=”15px”][\/vc_column][vc_column width=”1\/3″][vc_single_image image=”823″ img_size=”full” css=””][\/vc_column][\/vc_row][vc_row][vc_column width=”1\/4″][vc_single_image image=”597″ img_size=”large” onclick=”custom_link” img_link_target=”_blank” css_animation=”fadeIn” link=”https:\/\/cihr-irsc.gc.ca\/e\/193.html”][\/vc_column][vc_column width=”1\/4″][\/vc_column][vc_column width=”1\/4″][\/vc_column][vc_column width=”1\/4″][\/vc_column][\/vc_row]<\/p>\n<\/div>","protected":false},"excerpt":{"rendered":"

[vc_row margin_top=”20″ margin_bottom=”20″ bg_type=”image” parallax_style=”vcpb-default” bg_image_new=”443|https:\/\/lab.research.sickkids.ca\/hopyan\/wp-content\/uploads\/sites\/16\/2015\/12\/Snowflakesright-only-copy2.jpg” bg_override=”ex-full” parallax_content=”off” enable_overlay=”off” seperator_enable=”off” ult_hide_row=”off”][vc_column width=”2\/3″][vc_empty_space height=”5px”][vc_column_text css_animation=”fadeIn” css=””]In the embryo, many organs begin life as tiny, simple buds. \u00a0They grow, change shape, and arrange multiple types of cells into complex patterns as they mature into functioning organs. \u00a0The limbs, face, and heart are examples of organs for which…<\/p>\n","protected":false},"author":2,"featured_media":0,"parent":0,"menu_order":0,"comment_status":"closed","ping_status":"closed","template":"","meta":{"footnotes":""},"class_list":["post-6","page","type-page","status-publish","hentry","description-off"],"yoast_head":"\nHome - Hopyan Lab<\/title>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/lab.research.sickkids.ca\/hopyan\/\" \/>\n<meta property=\"og:locale\" content=\"en_US\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"Home\" \/>\n<meta property=\"og:description\" content=\"[vc_row margin_top=”20″ margin_bottom=”20″ bg_type=”image” parallax_style=”vcpb-default” bg_image_new=”443|https:\/\/lab.research.sickkids.ca\/hopyan\/wp-content\/uploads\/sites\/16\/2015\/12\/Snowflakesright-only-copy2.jpg” bg_override=”ex-full” parallax_content=”off” enable_overlay=”off” seperator_enable=”off” ult_hide_row=”off”][vc_column width=”2\/3″][vc_empty_space height=”5px”][vc_column_text css_animation=”fadeIn” css=””]In the embryo, many organs begin life as tiny, simple buds. \u00a0They grow, change shape, and arrange multiple types of cells into complex patterns as they mature into functioning organs. \u00a0The limbs, face, and heart are examples of organs for which…\" \/>\n<meta property=\"og:url\" content=\"https:\/\/lab.research.sickkids.ca\/hopyan\/\" \/>\n<meta property=\"og:site_name\" content=\"Hopyan Lab\" \/>\n<meta property=\"article:modified_time\" content=\"2025-12-10T18:41:04+00:00\" \/>\n<meta name=\"twitter:card\" content=\"summary_large_image\" \/>\n<meta name=\"twitter:label1\" content=\"Est. reading time\" \/>\n\t<meta name=\"twitter:data1\" content=\"2 minutes\" \/>\n<script type=\"application\/ld+json\" class=\"yoast-schema-graph\">{\"@context\":\"https:\/\/schema.org\",\"@graph\":[{\"@type\":\"WebPage\",\"@id\":\"https:\/\/lab.research.sickkids.ca\/hopyan\/\",\"url\":\"https:\/\/lab.research.sickkids.ca\/hopyan\/\",\"name\":\"Home - 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Hopyan Lab","robots":{"index":"index","follow":"follow","max-snippet":"max-snippet:-1","max-image-preview":"max-image-preview:large","max-video-preview":"max-video-preview:-1"},"canonical":"https:\/\/lab.research.sickkids.ca\/hopyan\/","og_locale":"en_US","og_type":"article","og_title":"Home","og_description":"[vc_row margin_top=”20″ margin_bottom=”20″ bg_type=”image” parallax_style=”vcpb-default” bg_image_new=”443|https:\/\/lab.research.sickkids.ca\/hopyan\/wp-content\/uploads\/sites\/16\/2015\/12\/Snowflakesright-only-copy2.jpg” bg_override=”ex-full” parallax_content=”off” enable_overlay=”off” seperator_enable=”off” ult_hide_row=”off”][vc_column width=”2\/3″][vc_empty_space height=”5px”][vc_column_text css_animation=”fadeIn” css=””]In the embryo, many organs begin life as tiny, simple buds. \u00a0They grow, change shape, and arrange multiple types of cells into complex patterns as they mature into functioning organs. \u00a0The limbs, face, and heart are examples of organs for which…","og_url":"https:\/\/lab.research.sickkids.ca\/hopyan\/","og_site_name":"Hopyan Lab","article_modified_time":"2025-12-10T18:41:04+00:00","twitter_card":"summary_large_image","twitter_misc":{"Est. reading time":"2 minutes"},"schema":{"@context":"https:\/\/schema.org","@graph":[{"@type":"WebPage","@id":"https:\/\/lab.research.sickkids.ca\/hopyan\/","url":"https:\/\/lab.research.sickkids.ca\/hopyan\/","name":"Home - 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