2025

  • Benjamin S, Vi L, Chatterjee D, Jaeggi ET, Ruffatti A, Hiraki LT, Sepiashvili L, Laskin CA, Fatah M, Tonello M, Dominguez D, Ng L, Lohbihler M, Luchessi AD, Hogarth K, Daoud A, Maynes JT, Protze S, Hamilton RM. Maternal autoantibodies to the sodium potassium pump α1 subunit AT1A1 and fetal autoimmune congenital heart block: a case-control study. Lancet Rheumatol. 2025 May 21:S2665-9913(25)00092-X. doi: 10.1016/S2665-9913(25)00092-X. Epub ahead of print. PMID: 40412415.
  • Carlomagno R, Gold N, Liao F, Cao J, Arnold PD, Burton CL, Crosbie J, Dominguez D, Gladman DD, Ishimori M, Jefferies C, Kamen DL, Kamphuis S, Klein-Gitelman MS, Knight AM, Lee CJ, Levy DM, Onel KB, Paterson AD, Peschken CA, Pope JE, Schachar RJ, Silverman ED, Strug L, Touma Z, Urowitz MB, Wallace DJ, Wang C, Webber D, Wither JE, Hiraki LT. Genetics of Childhood-onset Systemic Lupus Erythematosus (cSLE). Arthritis Rheumatol. 2025 May 12. doi: 10.1002/art.43227. Epub ahead of print. PMID: 40356234.
  • Sammaritano LR, Askanase A, Bermas BL, Dall’Era M, Duarte-García A, Hiraki LT, Rovin BH, Son MBF, Alvarado A, Aranow C, Barnado A, Broder A, Brunner HI, Chowdhary V, Contreras G, Felix C, Ferucci ED, Gibson KL, Hersh AO, Izmirly PM, Kalunian K, Kamen D, Rollins B, Smith BJ, Thomas A, Timlin H, Wallace DJ, Ward M, Azzam M, Bartels CM, Cunha JS, DeQuattro K, Fava A, Figueroa-Parra G, Garg S, Greco J, Cuéllar-Gutiérrez MC, Iyer P, Johannemann AS, Jorge A, Kasturi S, Kawtharany H, Khawandi J, Kirou KA, Legge A, Liang KV, Lockwood MM, Sanchez-Rodriguez A, Turgunbaev M, Williams JN, Turner AS, Mustafa RA. 2024 American College of Rheumatology (ACR) Guideline for the Screening, Treatment, and Management of Lupus Nephritis. Arthritis Rheumatol. 2025 May 7. doi: 10.1002/art.43212. Epub ahead of print. PMID: 40331662.
  • Chan RWY, Serpas L, Ni M, Volpi S, Hiraki LT, Tam LS, Rashidfarrokhi A, Wong PCH, Tam LHP, Wang Y, Jiang P, Cheng ASH, Peng W, Han DSC, Tse PPP, Lau PK, Lee WS, Magnasco A, Buti E, Sisirak V, AlMutairi N, Chan KCA, Chiu RWK, Reizis B, Lo YMD. Plasma DNA Profile Associated with DNASE1L3 Gene Mutations: Clinical Observations, Relationships to Nuclease Substrate Preference, and In Vivo Correction. Am J Hum Genet. 2025 May 1;112(5):1247. doi: 10.1016/j.ajhg.2025.04.001. Erratum for: Am J Hum Genet. 2020 Nov 5;107(5):882-894. doi: 10.1016/j.ajhg.2020.09.006. PMID: 40315821.
  • Zaffino I, Boulard L, Law J, Jeyanathan A, Ng L, Williams-Reid S, Reid K, Cortes A, Cortes E, Danguecan A, Levy DM, Hiraki LT, Knight AM. Understanding Contributors of Resilience in Youth with Childhood-Onset Systemic Lupus Erythematosus Through a Socio-ecological Lens: A Mixed Methods Study. Arthritis Care Res (Hoboken). 2025 Apr 14. doi: 10.1002/acr.25550. Epub ahead of print. PMID: 40223659.
  • Misztal MC, Liao F, Gold N, Cao J, Gladman DD, Touma Z, Wither J, Cook R, Urowitz M, Hiraki LT. Identified genetic locus for longitudinal disease activity in adults with systemic lupus erythematosus. Rheumatology (Oxford). 2025 Feb 25. doi: 10.1093/rheumatology/keaf093. Epub ahead of print. PMID: 40036173.
  • Diaz T, Danguecan A, Dominguez D, Knight A, Laskin CA, Levy DM, Jaeggi E, Misztal M, Mandhane P, Moraes T, Ng L, Silverio F, Silverman ED, Simons E, Turvey SE, Subbarao P, Hiraki LT. Long-Term Outcomes of Children Born to Anti-Ro Antibody-Positive Mothers With and Without Rheumatic Disease. Arthritis Care Res (Hoboken). 2025 Feb 21. doi: 10.1002/acr.25510. Epub ahead of print. PMID: 39981584.
  • Sadun RE, Cooper JC, Belot A, Avcin T, Aggarwal A, Ainsworth J, Akinsete A, Ardoin SP, Beresford MW, Bortey L, Brunner HI, Chang JC, Ciurtin C, Daftary A, Eberhard B, Feldman CH, Hedrich CM, Hersh AO, Hiraki LT, Isenberg DA, Kamphuis S, Knight AM, Lambert L, Levy DM, Marks SD, Maxwell N, Migowa A, Moore K, Ozen S, Ramsey-Goldman R, Ravelli A, Reeve BB, Rubinstein TB, Saad-Magalhaes C, Sawhney S, Schanberg LE, von Scheven E, Scott C, Son MB, Tony G, Weitzman ER, Wenderfer SE, Woodside A, Lewandowski LB, Smith EM; CARRA SLE Committee and PReS Lupus Working Party. Development of CARRA/PReS-endorsed consensus Core and Expanded Datasets in childhood-onset systemic lupus erythematosus for international registry-based research. Ann Rheum Dis. 2025 Feb;84(2):158-168. doi: 10.1136/ard-2024-226528. Epub 2025 Jan 2. PMID: 39919891.
  • Misztal MC, Gold N, Cao J, Diaz T, Dominguez D, Thompson K, Jaeggi E, Knight AM, Laskin C, Ng L, Silverman ED, Hiraki LT. Genetics of Neonatal Lupus Erythematosus Risk and Specific Manifestations. J Rheumatol. 2025 Jan 1;52(1):52-57. doi: 10.3899/jrheum.2023-1036. PMID: 38825356.

  • Charras A, Hiraki LT, Lewandowski L, Hedrich CM. Genetic and epigenetic factors shape phenotypes and outcomes in systemic lupus erythematosus – focus on juvenile-onset systemic lupus erythematosus. Curr Opin Rheumatol. 2025 Mar 1;37(2):149-163. doi: 10.1097/BOR.0000000000001072. Epub 2024 Dec 11. PMID: 39660463; PMCID: PMC11789615.
  • El Tal T, Chen A, Wong S, Jeyanathan A, Longmore A, Convery H, Finkelstein D, Hiraki L, Kulkarni C, Lerman N, Leslie K, Levy DM, Lorber S, Mwizerwa O, Ng L, Rawal V, Smith E, Toulany A, Knight AM. Improving routine mental health screening for depression and anxiety in a paediatric lupus clinic: a quality improvement initiative for enhanced mental healthcare. Lupus Sci Med. 2024 Oct 22;11(2):e001282. doi: 10.1136/lupus-2024-001282. PMID: 39438087; PMCID: PMC11499811.
  • Johnson SR, Alahmari H, Bonilla D, Ahmad Z, Bookman A, Hiraki LT, Silverman E, Touma Z, Movahedi M, Wither JE. Evaluation of Progression From Preclinical to Systemic Autoimmune Rheumatic Disease: Novel Use of the European Alliance of Associations for Rheumatology/American College of Rheumatology Systemic Lupus Erythematosus Classification Criteria as an Outcome Measure. ACR Open Rheumatol. 2024 Dec;6(12):871-877. doi: 10.1002/acr2.11723. Epub 2024 Sep 30. PMID: 39348240; PMCID: PMC11638143.
  • Choong N, Batthish M, Berard RA, Chédeville G, Feldman BM, Houghton KM, Huber AM, James S, Proulx-Gauthier JP, Rumsey DG, Schmeling H, Toupin-April K, Guzman J; CAPRI Registry Investigators. Relationship of Fatigue, Pain Interference, and Physical Disability in Children Newly Diagnosed With Juvenile Idiopathic Arthritis. Arthritis Care Res (Hoboken). 2024 Oct;76(10):1409-1418. doi: 10.1002/acr.25377. Epub 2024 Jun 17. PMID: 38769616.
  • Hayward K, Grom A, Muscal E, Nigrovic PA, Rouster-Stevens KA, Ardalan K, Hiraki L, Moorthy LN; A. C. R./CARRA Mentoring Interest Group. Longitudinal program evaluation of an inter-institutional mentorship network for pediatric rheumatology using a quality improvement framework. Pediatr Rheumatol Online J. 2024 Jul 10;22(1):64. doi: 10.1186/s12969-024-00993-1. PMID: 38982530; PMCID: PMC11234764.
  • Neufeld KM, Moaf P, Quilter M, Danguecan AN, Couture J, Dominguez D, Hendrikx O, Ng L, Schachter R, Korczak DD, Levy DM, Hiraki L, Knight AM. Evaluation of depressive and anxiety symptoms in childhood-onset systemic lupus erythematosus: Frequency, course, and associated risk factors. Lupus. 2024 Jul;33(8):874-885. doi: 10.1177/09612033241254170. Epub 2024 May 22. PMID: 38774953; PMCID: PMC11141111.
  • Kim G, Levy DM, Nicolson D, Minn S, Knight A, Hiraki LT, Lynch A, Jean-St-Michel E, Ashkanase J, Jeewa A. Severe Inflammatory Heart Disease in Children with Lupus: A Case Series. CJC Pediatr Congenit Heart Dis. 2024 May 31;3(4):161-164. doi: 10.1016/j.cjcpc.2024.05.005. PMID: 39493670; PMCID: PMC1152497
  • DeCoste C, Moaf P, Mohamed I, Ng L, Ostojic-Aitkens D, Levy DM, Hiraki LT, Toulany A, Knight AM. Adolescent health care needs and relationship to disease in patients with childhood-onset systemic lupus erythematosus. Arthritis Care Res (Hoboken). 2024 Jan 14. doi: 10.1002/acr.25297. PMID: 38221711 DOI: 10.1002/acr.25297

  • Van Zuydam NR, Ahlqvist E, Sandholm N, Deshmukh H, Rayner NW, Abdalla M, Ladenvall C, Ziemek D, Fauman E, Robertson NR, McKeigue PM, Valo E, Forsblom C, Harjutsalo V; FINNDIANE Study centres, Perna A, Rurali E, Marcovecchio ML, Igo RP Jr, Salem RM, Perico N, Lajer M, Käräjämäki A, Imamura M, Kubo M, Takahashi A, Sim X, Liu J, van Dam RM, Jiang G, Tam CHT, Luk AOY, Lee HM, Lim CKP, Szeto CC, So WY, Chan JCN; Hong Kong Diabetes Registry TRS Project Group, Ang SF, Dorajoo R, Wang L, Hua Clara TS, McKnight AJ, Duffy S; Warren 3/UK GoKinD Study Group, Pezzolesi MG, Consortium G, Marre M, Gyorgy B, Hadjadj S, Hiraki LT; DCCT/EDIC group, Ahluwalia TS, Almgren P, Schulz CA, Orho-Melander M, Linneberg A, Christensen C, Witte DR, Grarup N, Brandslund I, Melander O, Paterson AD, Tregouet D, Maxwell AP, Lim SC, Ma RCW, Tai ES, Maeda S, Lyssenko V, Tuomi T, Krolewski AS, Rich SS, Hirschhorn JN, Florez JC, Dunger D, Pedersen O, Hansen T, Rossing P, Remuzzi G; SUMMIT Consortium, Brosnan MJ, Palmer CNA, Groop PH, Colhoun HM, Groop LC, McCarthy MI. A Genome-Wide Association Study of Diabetic Kidney Disease in Subjects With Type 2 Diabetes. 2018 July; 67(7):1414-1427. PMID: 29703844
  • Borgia RE, Gerstein M, Levy D, Silverman ED**, Hiraki LT** (**Co-senior authors). Features, treatment and outcomes of macrophage activation syndrome in pediatric systemic lupus erythematosus. Arthritis & Rheumatology. 2018 April;70 (4): 616-624. PMID: 29342508
  • Lionel AC, Costain G, Monfared N, Walker S, Reuter MS, Hosseini SM, Thiruvahindrapuram B, Merico D, Jobling R, Nalpathamkalam T, Pellecchia G, Sung WWL, Wang Z, Bikangaga P, Boelman C, Carter MT, Cordeiro D, Cytrynbaum C, Dell SD, Dhir P, Dowling JJ, Heon E, Hewson S, Hiraki L, Inbar-Feigenberg M, Klatt R, Kronick J, Laxer RM, Licht C, MacDonald H, Mercimek-Andrews S, Mendoza-Londono R, Piscione T, Schneider R, Schulze A, Silverman E, Siriwardena K, Snead OC,Sondheimer N, Sutherland J, Vincent A, Wasserman JD, Weksberg R, Shuman C, Carew C, Szego MJ, Hayeems RZ, Basran R, Stavropoulos DJ, Ray PN, Bowdin S, Meyn MS, Cohn RD, Scherer SW, Marshall CR. Improved diagnostic yield compared with targeted gene sequencing panels suggests a role for whole-genome sequencing as a first-tier genetic test. Genetics in Medicine. 2018 April; 20 (4): 435-443. PMID: 28771251