{"id":18,"date":"2021-06-11T19:54:39","date_gmt":"2021-06-11T19:54:39","guid":{"rendered":"https:\/\/lab.research.sickkids.ca\/heath\/?page_id=18"},"modified":"2025-04-08T18:29:00","modified_gmt":"2025-04-08T18:29:00","slug":"publications","status":"publish","type":"page","link":"https:\/\/lab.research.sickkids.ca\/heath\/publications\/","title":{"rendered":"Publications"},"content":{"rendered":"<p><div class=\"fusion-fullwidth fullwidth-box fusion-builder-row-1 fusion-flex-container nonhundred-percent-fullwidth non-hundred-percent-height-scrolling\" style=\"--awb-border-radius-top-left:0px;--awb-border-radius-top-right:0px;--awb-border-radius-bottom-right:0px;--awb-border-radius-bottom-left:0px;--awb-padding-top:20px;--awb-padding-left:10px;--awb-margin-bottom:30px;--awb-flex-wrap:wrap;\" ><div class=\"fusion-builder-row fusion-row fusion-flex-align-items-flex-start fusion-flex-content-wrap\" style=\"max-width:1248px;margin-left: calc(-4% \/ 2 );margin-right: calc(-4% \/ 2 );\"><div class=\"fusion-layout-column fusion_builder_column fusion-builder-column-0 fusion_builder_column_1_1 1_1 fusion-flex-column\" style=\"--awb-padding-left:20px;--awb-bg-size:cover;--awb-border-color:#0046ad;--awb-border-left:5px;--awb-border-style:solid;--awb-width-large:100%;--awb-margin-top-large:0px;--awb-spacing-right-large:1.92%;--awb-margin-bottom-large:20px;--awb-spacing-left-large:0%;--awb-width-medium:100%;--awb-order-medium:0;--awb-spacing-right-medium:1.92%;--awb-spacing-left-medium:0%;--awb-width-small:100%;--awb-order-small:0;--awb-spacing-right-small:1.92%;--awb-spacing-left-small:1.92%;\"><div class=\"fusion-column-wrapper fusion-column-has-shadow fusion-flex-justify-content-flex-start fusion-content-layout-column\"><div class=\"fusion-text fusion-text-1\"><h2>2025<\/h2>\n<ul>\n<li>Robinson, C. , Aman, N. Banh, T., Brooke, J., Chanchlani, R., Cuthbertson, B., Dhillon, V., Fan, E., Langlois, V., Levin, L., Licht, C., McKay, A., Noone, D., Pearl, R., Radhakrishnan, S., Rowley, V., Wei Teoh, C., Vasilevska-Ristovska, J., Heath, A., Parekh, R. <a href=\"https:\/\/doi.org\/10.1001\/jamapediatrics.2024.5286\" target=\"_blank\" rel=\"noopener\">Comparative efficacy of non-steroid immunosuppressive medications in childhood nephrotic syndrome<\/a>. JAMA Pediatrics. 2025.<\/li>\n<li>Phillippo, D., Remiro-Azocar, A., Heath, A., Baio, G., Dias, S., Ades, A., Welton, N. <a href=\"https:\/\/doi.org\/10.1017\/rsm.2025.2\" target=\"_blank\" rel=\"noopener\">Effect modification and non-collapsibility together may lead to conflicting treatment decisions: A review of marginal and conditional estimands and recommendations for decision-making.<\/a>\u00a0Research Synthesis Methods. 2025.<\/li>\n<li>Wahid, L., Froess, J., Ortel, T., Zarychanski, T., Berger, J., Cushman, M., Angus, D., Renard, V., Farahani, P., Webb, S., Heath, A., et al. <a href=\"https:\/\/doi.org\/10.1161\/ATVBAHA.124.321108\" target=\"_blank\" rel=\"noopener\">Longitudinal On-Treatment Markers of Thromboinammation Identify Heterogeneity of Treatment Effect of Therapeutic-Dose Heparin in a Clinical Trial of Patients Hospitalized for COVID-19<\/a>. Arteriosclerosis, Thrombosis, and Vascular Biology. 2025; 41(1).<\/li>\n<\/ul>\n<\/div><div class=\"fusion-text fusion-text-2\"><h2>2024<\/h2>\n<ul>\n<li>Tran, N-A., McGrory, A., Poonai, N., Heath, A. <a href=\"https:\/\/doi.org\/10.1177\/17407745241251812\" target=\"_blank\" rel=\"noopener\">A comparison of alternative ranking methods in two-stage clinical trials with multiple interventions: an application to the anxiolysis for laceration repair in children trial<\/a>. Clin Trials. 2024.<\/li>\n<li>Chen, Z., Harhay, M., Fan, E., Granholm, A., McAuley, D., Urner, M., Yarnell, C., Goligher, E., Heath, A. <a href=\"https:\/\/doi.org\/10.1097\/CCE.0000000000001152\" target=\"_blank\" rel=\"noopener\">Statistical power and performance of strategies to analyze composites of survival and duration of ventilation in clinical trials. Critical Care Explorations<\/a>. 2024; 20;6(10): e1152.<\/li>\n<li>Siu, A., Tran, N.-A., Ali, S., Coyle, D., Mahmood, Q., Pechlivanoglou, P., Poonai, N., Heath, A.<a href=\"http:\/\/10.1097\/PEC.0000000000003020\" target=\"_blank\" rel=\"noopener\"> Anxiolytic Agents for Managing Distress During Laceration Repair in Children: A Systematic Review<\/a>. Pediatric Emergency Care. 2024; 40(2): 88-97.<\/li>\n<li>Li, L., Jalal, H., Heath, A. <a href=\"https:\/\/doi.org\/10.1177\/0272989X241264287\" target=\"_blank\" rel=\"noopener\">Accurate EVSI Estimation for Nonlinear Models Using the Gaussian Approximation Method. Medical Decision Making<\/a>. 2024; 44(7):787- 801.<\/li>\n<li>Wang, J.-Y., Speechley, K., Anderson, K., Gainham, G., Ali, S., Doyon-Trottier, E., Sabhaney, V., Heath, A., Forbes, A., Poonai, N. <a href=\"https:\/\/doi.org\/10.1007\/s43678-024-00731-2\" target=\"_blank\" rel=\"noopener\">Intranasal Midazolam for Procedural Distress in Children: A Systematic Review and Meta-Analysis<\/a>. Canadian Journal of Emergency Medicine. 2024; 26(1): 658-670.<\/li>\n<li>Siu, A., Tran, N.-A., Ali, S., Coyle, D., Mahmood, Q., Pechlivanoglou, P., Poonai, N., Heath, A. Pharmacologic Procedural Distress Management During Laceration Repair in Children: A Systematic Review. Pediatric Emergency Care. 2024; 40(2):88-97.<\/li>\n<li>Bosma, K., Lafreniere-Roula, M., Jiang, A., Heath, A., Ouyang, Y., et al. <a href=\"https:\/\/doi.org\/10.1186\/s13063-024-08669-7\" target=\"_blank\" rel=\"noopener\">Proportional Assist Ventilation for Minimizing the Duration of Mechanical Ventilation (the PROMIZING study): update to the statistical analysis plan for a randomized controlled trial<\/a>. Trials, 2024; 25: 885.<\/li>\n<li>* Robinson, C. *, Parekh, R., Cuthbertson, B., Fan, E., Ouyang, Y., Heath, A. <a href=\"https:\/\/doi.org\/10.1681\/ASN.0000000565\" target=\"_blank\" rel=\"noopener\">Using Simulation to Optimize the Design of Adaptive Clinical Trials<\/a>. Journal of the American Society of Nephrology. 2024.<\/li>\n<li>Ben Eltriki, M., Chhabra, M., Rafiq, A., Paul, A., Prabhu, D., Afolabi, M., Bashaw, R., Neilson, C., Mahmud, S., Lacaze-Masmonteil, T., Marlin, S., Klassen, T., Offringa, M., Butcher, N., Heath, A., Driedger, M., Kelly, L. <a href=\"https:\/\/doi.org\/10.1186\/s12874-024-02272-9\" target=\"_blank\" rel=\"noopener\">Adaptive designs in clinical trials: a systematic review-part I.<\/a> BMC Medical Research Methodology, 2024; 24:229.<\/li>\n<li>Goligher, E., Heath, A., Harhay, M. <a href=\"http:\/\/10.1016\/S0140-6736(24)01295-9\" target=\"_blank\" rel=\"noopener\">Bayesian statistics for clinical research<\/a>. Lancet, 2024; 404(10457):1067-1076.<\/li>\n<li>Baba, A., Aregbesola, A., Caldwell, P., Elliott, S., Elsman, E., Fernandes, R., Hartling, L., Heath, A., Kelly, L., Preston, J., Sammy, A., Webbe, J., Williams, K., Woolfall, K., Klassen, T., Offringa, M. on behalf of StaR Child Health. <a href=\"https:\/\/doi.org\/10.1542\/peds.2024-065799\" target=\"_blank\" rel=\"noopener\">Developments in the Design, Conduct, and Reporting of Child Health Trials.<\/a> Pediatrics. 2024;154(1): e2024065799.<\/li>\n<li>Ganji, N., Kalish, B., Offringa, M., Li, B., Anderson, J., Baruchel, S., Blakely, M., De Coppi, P., Eaton, S., Gauda, E., Hall, N., Heath, A., Livingston, M., McNair, C., Mitchell, R., Patel, K., Pechlivanoglou, P., et al. <a href=\"https:\/\/doi.org\/10.1038\/s41390-024-03236-x\" target=\"_blank\" rel=\"noopener\">Translating Regenerative Medicine Therapies in Neonatal Necrotizing Enterocolitis<\/a>. Pediatric Research. 2024; 96(1): 1609-1615.<\/li>\n<li>Hosseini, R., Chen, Z., Goligher, E., Fan, E., Ferguson, N., Harhay, M., Sahetya, S., Urner, M., Yarnell, C., Heath, A. <a href=\"https:\/\/doi.org\/10.1016\/j.cct.2024.107560\" target=\"_blank\" rel=\"noopener\">Designing a Bayesian adaptive clinical trial to evaluate ventilation procedures in critical care using Integrated Nested Laplace Approximations. Contemporary Clinical Trials<\/a>. 2024; 142:107560.<\/li>\n<li>Marks, Y., Hoch, J., Heath, A., Pechlivanoglou, P. <a href=\"https:\/\/doi.org\/10.1007\/s40273-024-01374-y\" target=\"_blank\" rel=\"noopener\">Barriers and facilitators of using R for decision analytic modelling in health technology assessment: Focus group results<\/a>. Pharmacoeconomics. 2024; 42(1): 783-795.<\/li>\n<li>Heath, A., Manolopoulou, I., Baio, G., and Welton, N. <a href=\"https:\/\/doi.org\/10.1007\/s40273-024-01372-0\" target=\"_blank\" rel=\"noopener\">Value of Information for clinical trial design: the importance of considering all relevant comparators<\/a>. Pharmacoeconomics. 2024; 42, 479-486.<\/li>\n<li>Chen, Z., Berger, J., Castellucci, L., Farkouh, M., Goligher, E., Hade, E., Hunt, B., Kornblith, L., Lawler, P., Leifer, E., Lorenzi, E., Neal, M., Zarychanski, R., Heath, A. <a href=\"https:\/\/doi.org\/10.1177\/17407745241247334\" target=\"_blank\" rel=\"noopener\">A Comparison of Computational Algorithms for the Bayesian Analysis of Clinical Trials. Clinical Trials. <\/a>2024; 21(6): 689-700.<\/li>\n<li>Bos, L., Calfee, C., Castellvi-Font, A., Cornelius, V., Derde, L., Docherty, A., Fan, E., Gerguson, N., Goligher, E., Gordon, A., Granholm, A., Harhay, M., Heath, A., et al. <a href=\"https:\/\/doi.org\/10.1164\/rccm.202401-0101CP\" target=\"_blank\" rel=\"noopener\">The Rise of Adaptive Platform Trials in Critical Care<\/a>. Critical Care. 2024; 209(5):491-496.<\/li>\n<li>Remiro Azocar, A. , Heath, A., Baio, G. Model-based standardization using multiple imputation. BMC Medical Research Methodology. 2024; 24, 32. DOI: <a href=\"https:\/\/doi.org\/10.1186\/s12874-024-02157-x\">https:\/\/doi.org\/10.1186\/s12874-024-02157-x<\/a><\/li>\n<li>Yarnell, C., Barrett, K., Heath, A., Herridge, M., Fowler, R., Sung, L., Naimark, S., Tomlinson, G. <a href=\"http:\/\/10.1097\/CCE.0000000000001098\" target=\"_blank\" rel=\"noopener\">What is the potential value of a randomized trial of different thresholds to initiate invasive ventilation? A health economic analysis<\/a>. Critical Care Explorations. 2024; 4;6(6): e1098.<\/li>\n<li>Kunst, N., Siu, A., Drummond, M., Grimm, S., Grutters, J., Husereau, D., Koffijberg, E., Rothery, C., Wilson, E., Heath, A. <a href=\"https:\/\/doi.org\/10.1007\/s40258-023-00856-y\" target=\"_blank\" rel=\"noopener\">Comment on: Adding Value to CHEERS: New Reporting Standards for Value of Information Analyses<\/a>. Applied Health Economics and Health Policy.\u00a0 2024; 22: 265-267.<\/li>\n<\/ul>\n<\/div><\/div><\/div><\/div><\/div><div class=\"fusion-fullwidth fullwidth-box fusion-builder-row-2 fusion-flex-container nonhundred-percent-fullwidth non-hundred-percent-height-scrolling\" style=\"--awb-border-radius-top-left:0px;--awb-border-radius-top-right:0px;--awb-border-radius-bottom-right:0px;--awb-border-radius-bottom-left:0px;--awb-padding-top:20px;--awb-padding-left:10px;--awb-margin-bottom:30px;--awb-flex-wrap:wrap;\" ><div class=\"fusion-builder-row fusion-row fusion-flex-align-items-flex-start fusion-flex-content-wrap\" style=\"max-width:1248px;margin-left: calc(-4% \/ 2 );margin-right: calc(-4% \/ 2 );\"><div class=\"fusion-layout-column fusion_builder_column fusion-builder-column-1 fusion_builder_column_1_1 1_1 fusion-flex-column\" style=\"--awb-padding-left:20px;--awb-bg-size:cover;--awb-border-color:#0046ad;--awb-border-left:5px;--awb-border-style:solid;--awb-width-large:100%;--awb-margin-top-large:0px;--awb-spacing-right-large:1.92%;--awb-margin-bottom-large:20px;--awb-spacing-left-large:0%;--awb-width-medium:100%;--awb-order-medium:0;--awb-spacing-right-medium:1.92%;--awb-spacing-left-medium:0%;--awb-width-small:100%;--awb-order-small:0;--awb-spacing-right-small:1.92%;--awb-spacing-left-small:1.92%;\"><div class=\"fusion-column-wrapper fusion-column-has-shadow fusion-flex-justify-content-flex-start fusion-content-layout-column\"><div class=\"fusion-text fusion-text-3\"><h2>2023<\/h2>\n<ul>\n<li>Poonai, N., Sabhaney, V., Ali, S., Stevens, H., Bhatt, M., Doyon-Trottier, E., Brahmbhatt, S., Coriolano, K., Chapman, A., Evans, N., Mace, C., Creene, C., Meulendyks, S., Heath, A. <a href=\"https:\/\/doi.org\/10.1016\/j.annemergmed.2023.01.023\" target=\"_blank\" rel=\"noopener\">\u201cOptimal dose of intranasal dexmedetomidine for laceration repair in children: a phase II dose-ranging study using the Bayesian continual reassessment method.\u201d<\/a> Accepted to <em>Annals of Emergency Medicine.<\/em><\/li>\n<li>Walborn, A., Heath, A., Neal, M., Zarychanski, R., Kornblith, L., Hunt, B., Castellucci, L., Hochman, J., Paul, J. <a href=\"https:\/\/doi.org\/10.1016\/j.rpth.2023.102203\" target=\"_blank\" rel=\"noopener\">Effects of Inflammation on Thrombosis and Outcomes in COVID-19: Secondary Analysis of the ATTACC\/ACTIV-4a Trial. Research and Practice in Thrombosis and Haemostasis (RPTH)<\/a>. 2023; 7(7): 102203.<\/li>\n<li>Smilowitz, N., Hade, E., Kornblith, L., Castellucci, L., Cushman, M., Farkouh, M., Gong, M., Heath, A., et al. <a href=\"https:\/\/doi.org\/10.1016\/j.rpth.2023.102167\" target=\"_blank\" rel=\"noopener\">Effect of Therapeutic-Dose Heparin on Acute Kidney Injury in Non-Critically Ill Patients Hospitalized for COVID-19. Research and Practice in Thrombosis and Haemostasis<\/a>. 2023; 7(6):102167.<\/li>\n<li>Kunst, N., Siu, A., Drummond, M., Grimm, S., Grutters, J., Husereau, D., Koffijberg, E., Rothery, C., Wilson, E., Heath, A. <a href=\"https:\/\/doi.org\/10.1016\/j.jval.2023.06.014\" target=\"_blank\" rel=\"noopener\">Value of Information: CHEERS Extension Reporting Standards Explanation and Elaboration<\/a>. Value in Health. 2023; 26(10):1461-1473.<\/li>\n<li>Remiro Azocar, A., Heath, A., Baio, G. <a href=\"https:\/\/doi.org\/10.1002\/jrsm.1645\" target=\"_blank\" rel=\"noopener\">Methodological considerations for novel approaches to covariate-adjusted indirect treatment comparisons<\/a>. Research Synthesis Methods. 2023; 14(4): 652-658.<\/li>\n<li>Goligher, E., Heath, A. <a href=\"https:\/\/doi.org\/10.1513\/AnnalsATS.202302-169ED\" target=\"_blank\" rel=\"noopener\">Bringing clinical trials to the bedside: conditional average treatment effect in the BASICS trial<\/a>. Annals of the American Thoracic Society. 2023; 20(6): 794-796.<\/li>\n<li>* Vervaart, M.*, Aas, E., Claxton, K., Strong, M., Welton, N., Wisloff, T., Heath, A. <a href=\"https:\/\/doi.org\/10.1177\/0272989X231162069\" target=\"_blank\" rel=\"noopener\">General-Purpose Methods for Simulating Survival Data for Expected Value of Sample Information Calculations<\/a>. Medical Decision Making. 2023; 43(5): 595-609.<\/li>\n<li>Pitre, T., Cheung, S., Cusano, E., Khan, N., Mikhail, D., Leung, G., Vernooij, R., Yarnell, C., Goligher, E., Murthy, S., Heath, A., Mah, J., Rochwerg, B., Zeraatkar, D. <a href=\"https:\/\/doi.org\/10.1016\/j.jclinepi.2023.02.010\" target=\"_blank\" rel=\"noopener\">Methodology and Design of Platform Trials: A meta-epidemiological study<\/a>. Journal of Clinical Epidemiology. 2023; 157: 1-12.<\/li>\n<li>Poonai, N., Sabhaney, V., Ali, S., Stevens, H., Bhatt, M., Doyon-Trottier, E., Brahmbhatt, S., Coriolano, K., Chapman, A., Evans, N., Mace, C., Creene, C., Meulendyks, S., Heath, A. <a href=\"https:\/\/doi.org\/10.1016\/j.annemergmed.2023.01.023\" target=\"_blank\" rel=\"noopener\">Optimal dose of intranasal dexmedetomidine for laceration repair in children: a phase II dose-ranging study using the Bayesian continual reassessment method<\/a>. Annals of Emergency Medicine. 2023; 82(2):179-190.<\/li>\n<\/ul>\n<\/div><\/div><\/div><div class=\"fusion-layout-column fusion_builder_column fusion-builder-column-2 fusion_builder_column_1_1 1_1 fusion-flex-column\" style=\"--awb-padding-left:20px;--awb-bg-size:cover;--awb-border-color:#0046ad;--awb-border-left:5px;--awb-border-style:solid;--awb-width-large:100%;--awb-margin-top-large:0px;--awb-spacing-right-large:1.92%;--awb-margin-bottom-large:20px;--awb-spacing-left-large:0%;--awb-width-medium:100%;--awb-order-medium:0;--awb-spacing-right-medium:1.92%;--awb-spacing-left-medium:0%;--awb-width-small:100%;--awb-order-small:0;--awb-spacing-right-small:1.92%;--awb-spacing-left-small:1.92%;\"><div class=\"fusion-column-wrapper fusion-column-has-shadow fusion-flex-justify-content-flex-start fusion-content-layout-column\"><div class=\"fusion-text fusion-text-4\"><h2>2022<\/h2>\n<ul>\n<li>Green, N., Heath, A., Baio, G. <a href=\"https:\/\/doi.org\/10.21105\/joss.04206\" target=\"_blank\" rel=\"noopener\">\u201cBCEA: An R Package for Cost Effectiveness Analysis.\u201d<\/a> The <em>Journal of Open Source Software<\/em>, 7(77): 4206, 2022.<\/li>\n<li>Park, J., Sharif, B., Harari, O., Dron, L., Heath, A., Meade, M., Zarychanski, R., Lee, R., Tremblay, G., Mills, E., Jemiai, Y., Mehta, C., Wathen, K. <a href=\"https:\/\/doi.org\/10.1371\/journal.pone.0268948\" target=\"_blank\" rel=\"noopener\">\u201cEconomic evaluation of cost and time required for a platform trial vs conventional trials.\u201d<\/a> <em>JAMA Network Open<\/em>, 5(7): e2221140, 2022.<\/li>\n<li>Remiro Azocar, A., Heath, A., Baio, G., <a href=\"https:\/\/doi.org\/10.1002\/jrsm.1565\" target=\"_blank\" rel=\"noopener\">\u201cParametric G-computation for Compatible Indirect Treatment Comparisons with Limited Individual Patient Data.&#8221;<\/a> Research Synthesis Methods.13(6):716-774, 2022.<\/li>\n<li>Lan, J., Plint, A., Dalzel, S., Klassen, T., Offringa, M., Heath, A. <a href=\"https:\/\/doi.org\/10.1186\/s13063-022-06240-w\" target=\"_blank\" rel=\"noopener\">\u201cRemote expert elicitation to determine the prior probability distribution for Bayesian sample size determination in international randomized controlled trials: Application to the Bronchiolitis in Infants Placebo Versus Epinephrine and Dexamethasone (BIPED) Study&#8221;<\/a>. Trials. 23:279, 2022.<\/li>\n<li>Heath, A., and Pechlivanoglou, P. <a href=\"https:\/\/doi.org\/10.1177\/0272989X2110728\" target=\"_blank\" rel=\"noopener\">\u201cPrioritising Research in an Era of Personalised Medicine: The Potential Value of Unexplained Heterogeneity.\u201d<\/a> Medical Decision Making. 42(5): 649-660, 2022.<\/li>\n<li>Heath, A. <a href=\"https:\/\/doi.org\/10.1177\/0272989X2110730\" target=\"_blank\" rel=\"noopener\">\u201cCalculating Expected Value of Sample Information Adjusting for Imperfect Implementation.\u201d<\/a> Medical Decision Making. 42(5): 626-636, 2022.<\/li>\n<li>Flores Pimentel, M., Heath, A., Wan, M., Hussein, R., Leahy, K., MacDonald, H., Tavares, E., VandenHoven, C., MacNeill, K., Kannu, P., Parkins, P., Heon, E., Reginald, A., Vincent, A. <a href=\"https:\/\/lab.research.sickkids.ca\/heath\/contact\/\" target=\"_blank\" rel=\"noopener\">\u201cPrevalence of Choroidal Abnormalities and Lisch Nodules in Clinically Diagnosed and Molecular Confirmed Cohorts of Pediatric Neurofibromatosis Type 1.\u201d<\/a> Translational Vision Science &amp; Technology (TVST), 11(2):10.<\/li>\n<li>Remiro Azocar, A., Heath, A., Baio, G., <a href=\"https:\/\/doi.org\/10.1002\/sim.9286\" target=\"_blank\" rel=\"noopener\">Effect modification in anchored indirect treatment comparisons: Comments on \u201cMatching-adjusted indirect comparisons: Application to time-to-event data.\u201d<\/a> Statistics in Medicine, 41(8): 1541-1553, 2022.<\/li>\n<li>\u00a0Jackson, C., Baio, G., Heath, A., Strong, M., Welton, N., Wilson, E. <a href=\"https:\/\/doi.org\/10.1146\/annurev-statistics-040120-010730\" target=\"_blank\" rel=\"noopener\">\u201cValue of Information Analysis in Models to inform Health Policy.\u201d<\/a> Annual Reviews in Statistics and its Applications, 9(1): 95-118, 2022.<\/li>\n<\/ul>\n<\/div><\/div><\/div><\/div><\/div><div class=\"fusion-fullwidth fullwidth-box fusion-builder-row-3 fusion-flex-container nonhundred-percent-fullwidth non-hundred-percent-height-scrolling\" style=\"--awb-border-radius-top-left:0px;--awb-border-radius-top-right:0px;--awb-border-radius-bottom-right:0px;--awb-border-radius-bottom-left:0px;--awb-padding-top:20px;--awb-padding-left:10px;--awb-margin-bottom:30px;--awb-flex-wrap:wrap;\" ><div class=\"fusion-builder-row fusion-row fusion-flex-align-items-flex-start fusion-flex-content-wrap\" style=\"max-width:1248px;margin-left: calc(-4% \/ 2 );margin-right: calc(-4% \/ 2 );\"><div class=\"fusion-layout-column fusion_builder_column fusion-builder-column-3 fusion_builder_column_1_1 1_1 fusion-flex-column\" style=\"--awb-padding-left:20px;--awb-bg-size:cover;--awb-border-color:#0046ad;--awb-border-left:5px;--awb-border-style:solid;--awb-width-large:100%;--awb-margin-top-large:0px;--awb-spacing-right-large:1.92%;--awb-margin-bottom-large:20px;--awb-spacing-left-large:0%;--awb-width-medium:100%;--awb-order-medium:0;--awb-spacing-right-medium:1.92%;--awb-spacing-left-medium:0%;--awb-width-small:100%;--awb-order-small:0;--awb-spacing-right-small:1.92%;--awb-spacing-left-small:1.92%;\"><div class=\"fusion-column-wrapper fusion-column-has-shadow fusion-flex-justify-content-flex-start fusion-content-layout-column\"><div class=\"fusion-text fusion-text-5\"><h2>2021<\/h2>\n<ul>\n<li>Poonai, N., Coriolano, K., Klassen, T., Heath, A., Yaskina, M., Beer, D., Sawyer, S., Bhatt, M., Kam, A., Doah, Q., Sabhaney, V., Offringa, M., Pechlivanoglou, P., Hickes, S., and Ali, S., on behalf of the KidsCAN PERC iPCT-SPOR (Innovative Paediatric Clinical Trials &#8211; Strategy for Patient Oriented Research) Ketodex Study Team. (2021) <a href=\"https:\/\/bmjopen.bmj.com\/content\/10\/12\/e041319\" target=\"_blank\" rel=\"noopener\">Study protocol for intranasal dexmedetomidine plus ketamine for procedural sedation in children: an adaptive randomized controlled non-inferiority multicenter trial (Ketodex)<\/a>. <em>BMJ Open<\/em>. 10(12): e041319 &#8211; e041319.<\/li>\n<li>Heath, A. (2021) <a href=\"https:\/\/doi.org\/10.1177\/0272989X211073098\" target=\"_blank\" rel=\"noopener\">Calculating Expected Value of Sample Information Adjusting for Imperfect Implementation<\/a>. <em>Medical Decision Making<\/em>.<\/li>\n<li>Heath, A., Rios, D., Pullenayegum, E., Pechlivanoglou, P., Offringa, M., Yaskina, M., Watts, R., Riimmer, S., Klassen, T., De Silva, K., Poonai, N. on behalf of the PERC-KIDSCAN Ketodex Study Group. (2021) <a href=\"http:\/\/dx.doi.org\/https:\/\/doi.org\/10.1186\/s13063-020-04946-3\" target=\"_blank\" rel=\"noopener\">The intranasal dexmedetomidine plus ketamine for procedural sedation in children study (the Ketodex trial): Statistical Analysis Plan<\/a>. <em>Trials<\/em>. 22(1): 15-15.<\/li>\n<li>Ali, S., Hopkin, G., Poonai, N., Richer, L., Yaskina, M., Heath, A., Klassen T., McCabe, C., KidsCAN PERC Innovative Pediatric Clinical Trials; KidsCAN PERC Innovative Pediatric Clinical Trials Methods Core. (2021) <a href=\"http:\/\/dx.doi.org\/https:\/\/doi.org\/10.1186\/s13063-021-05164-1\" target=\"_blank\" rel=\"noopener\">A Novel Preference-Informed Complementary Trials (PICT) Design for Clinical Trial Research Influenced by Strong Patient Preferences<\/a>. <em>Trails.<\/em><\/li>\n<li>A Heath, M Strong, D Glynn, N Kunst, N J Welton, J D Goldhaber-Fiebert. <a href=\"http:\/\/dx.doi.org\/https:\/\/doi.org\/10.1177\/0272989X211026292\" target=\"_blank\" rel=\"noopener\">Simulating Study Data to Support Expected Value of Sample Information Calculations: A Tutorial.<\/a> <em>Medical Decision Making.<\/em><\/li>\n<li>Heath, A.<strong>,<\/strong> Hunink, M., Krijkamp, E., Pechlivanoglou, P. (2021) <a href=\"http:\/\/dx.doi.org\/https:\/\/doi.org\/10.1007\/s10654-021-00761-5\" target=\"_blank\" rel=\"noopener\">Prioritisation and design of clinical trials. European Journal of Epidemiology<\/a>. 36: 1111\u20131121.<\/li>\n<li>Remiro Azocar, A., Heath, A., Baio, G. (2021). <a href=\"http:\/\/dx.doi.org\/https:\/\/doi.org\/10.1002\/jrsm.1511\" target=\"_blank\" rel=\"noopener\">Methods for Population Adjustment with Limited Access to Individual Patient Data: A Simulation Study<\/a>. <em>Research Synthesis Methods.<\/em><\/li>\n<li>Daniel, A., Bwanali, M., Tenthani, J., Gladstone, M., Voskuijl, W., Potani, I., Ziwoya F., Chidzalo, K., Mbale, E., Heath, A., Bourdon, C., Njirammadzi, J., Heuvel, M., Bandsma, R. (2021) <a href=\"http:\/\/dx.doi.org\/https:\/\/doi.org\/10.1093\/cdn\/nzab100\" target=\"_blank\" rel=\"noopener\">A mixed methods cluster-randomized controlled trial of a hospital-based psychosocial stimulation and counseling program for caregivers and children with severe acute malnutrition<\/a>. <em>Current Developments in Nutrition<\/em>. 5(8): nzab100- nzab100.<\/li>\n<li>Aregbesola, A., Gates, A., Coyle, A., Sim, S., Vandermeer, B., Skakum, M., Contopoulos-Ioannidis, D., Heath, A., Hartling, L., Klassen, T. (2021) <a href=\"http:\/\/dx.doi.org\/https:\/\/doi.org\/10.1186\/s13643-021-01622-8\" target=\"_blank\" rel=\"noopener\">P-value and Bayesian analysis in randomized-controlled trials in child health research published over ten years, 2007 to 2017: a methodological review protocol<\/a>. <em>Systematic Reviews<\/em>. 10: 71.<\/li>\n<li>Remiro-Az\u00f3car, A., Heath, A., Baio, G. (2021) <a href=\"http:\/\/dx.doi.org\/https:\/\/doi.org\/10.1002\/sim.8857\" target=\"_blank\" rel=\"noopener\">Conflating marginal and conditional treatment effects: comments on &#8220;Assessing the performance of population adjustment methods for anchored indirect comparisons: A simulation study&#8221;<\/a>. <em>Statistics in Medicine<\/em>. 40(11): 2753-2758.<\/li>\n<li>Heath, A., Yaskina, M., Pechlivanoglou, P., Rios, J., Offringa, M., Klassen, T., Poonai, N., Pullenayegum, E. (2021) <a href=\"http:\/\/dx.doi.org\/https:\/\/doi.org\/10.1177\/1740774520965173\" target=\"_blank\" rel=\"noopener\">A Bayesian response-adaptive dose finding and comparative effectiveness trial<\/a>. <em>Clinical Trials: Journal of the Society for Clinical Trials<\/em>. 18(1): 61-70.<\/li>\n<\/ul>\n<\/div><\/div><\/div><\/div><\/div><div class=\"fusion-fullwidth fullwidth-box fusion-builder-row-4 fusion-flex-container nonhundred-percent-fullwidth non-hundred-percent-height-scrolling\" style=\"--awb-border-radius-top-left:0px;--awb-border-radius-top-right:0px;--awb-border-radius-bottom-right:0px;--awb-border-radius-bottom-left:0px;--awb-padding-top:20px;--awb-padding-left:10px;--awb-margin-bottom:30px;--awb-flex-wrap:wrap;\" ><div class=\"fusion-builder-row fusion-row fusion-flex-align-items-flex-start fusion-flex-content-wrap\" style=\"max-width:1248px;margin-left: calc(-4% \/ 2 );margin-right: calc(-4% \/ 2 );\"><div class=\"fusion-layout-column fusion_builder_column fusion-builder-column-4 fusion_builder_column_1_1 1_1 fusion-flex-column\" style=\"--awb-padding-left:20px;--awb-bg-size:cover;--awb-border-color:#0046ad;--awb-border-top:0px;--awb-border-right:0px;--awb-border-bottom:0px;--awb-border-left:5px;--awb-border-style:solid;--awb-width-large:100%;--awb-margin-top-large:0px;--awb-spacing-right-large:1.92%;--awb-margin-bottom-large:20px;--awb-spacing-left-large:0%;--awb-width-medium:100%;--awb-order-medium:0;--awb-spacing-right-medium:1.92%;--awb-spacing-left-medium:0%;--awb-width-small:100%;--awb-order-small:0;--awb-spacing-right-small:1.92%;--awb-spacing-left-small:1.92%;\"><div class=\"fusion-column-wrapper fusion-column-has-shadow fusion-flex-justify-content-flex-start fusion-content-layout-column\"><div class=\"fusion-text fusion-text-6\"><h2>2020<\/h2>\n<ul>\n<li>Freedman, S., Williamson-Urquhart, S., Heath, A., Pechlivanoglou, P., Hopkin, G., Gouin, S., Plint, A., Dixon, A., Beer, A., Joubert. G.; McCabe, C., Finkelstein, Y., Klassen, T. on behalf of the KidsCANPediatric Emergency Research Canada (PERC) Innovative Pediatric Clinical Trials DOSE-AGE Study Group. (2020). <span style=\"text-decoration: underline\"><a href=\"https:\/\/doi.org\/10.1186\/s13063-020-04347-6\" target=\"_blank\" rel=\"noopener\">Multi-dose Oral Ondansetron for Pediatric Gastroenteritis: Study Protocol for the multiDOSE oral ondansetron for pediatric Acute GastroEnteritis (DOSE-AGE) Pragmatic Randomized Controlled Trial<\/a><\/span>. <em>Trials<\/em>. 21(435): 1-13.<\/li>\n<\/ul>\n<ul>\n<li>Heath, A., Offringa, M., Pechlivanoglou, P., Rios, J., Klassen, T., Poonai, N., Pullenayegum,E. (2020). <span style=\"text-decoration: underline\"><a href=\"http:\/\/dx.doi.org\/https:\/\/doi.org\/10.1016\/j.conctc.2020.100561\" target=\"_blank\" rel=\"noopener\">Determining a Bayesian Predictive Power Stopping Rule for Futility in a Non-Inferiority Trial with Binary Outcomes: The INK trial<\/a><\/span>. Contemporary Clinical Trials Communications. 18(1005616): 1-6.<\/li>\n<li>Remiro-Az\u00f3car, A., Heath, A., Baio, G. (2020). <span style=\"text-decoration: underline\"><a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/33963582\/\" target=\"_blank\" rel=\"noopener\">Conflating marginal and conditional treatment effects: comments on Assessing the performance of population adjustment methods for anchored indirect comparisons: A simulation study<\/a><\/span>. <em>Statistics in Medicine.<\/em><\/li>\n<\/ul>\n<ul>\n<li>Kunst, N., Wilson, E., Alarid-Escudero, F., Baio, G., Brennan, A., Fairley, M., Glynn, D., GoldhaberFiebert, J., Jackson, C., Jalal, H., Menzies, N., Strong, M., Thom, H., and Heath, A<strong>.<\/strong> (2020). <span style=\"text-decoration: underline\"><a href=\"https:\/\/arxiv.org\/abs\/1910.03368\" target=\"_blank\" rel=\"noopener\">Computing the Expected Value of Sample Information efficiently: Expertise and Skills Required for Four Model-Based Methods<\/a><\/span>. V<em>alue in Health<\/em>. 23(6): 734\u2013742.<\/li>\n<\/ul>\n<ul>\n<li>Heath, A., Yaskina, M., Hopkin, G., McCabe, C., Offringa, M., Pechlivanoglou, P., Rios, D., Poonai, N., Ali, S. on behalf of the PERC-KIDSCAN NO OUCH Trials Study Group. (2020). <span style=\"text-decoration: underline\"><a href=\"http:\/\/dx.doi.org\/http:\/\/doi.org\/10.1186\/s13063-020-04503-y\" target=\"_blank\" rel=\"noopener\">Non-Steroidal or Opioid Analgesia Use for Children with Musculoskeletal Injuries (No OUCH Trials): A Statistical Analysis Plan<\/a><\/span>. <em>Trials<\/em>. 21: 759.<\/li>\n<\/ul>\n<ul>\n<li>Aoyama, K., Heath, A.<strong>,<\/strong> Yang, A., Maynes, J., Petroz, G., Robertson, J., McDonnell, C.,Velummailum, R., Bond, E., Pechlivanoglou, P. (2020). <span style=\"text-decoration: underline\"><a href=\"https:\/\/doi.org\/10.1007\/s12630-020-01771-9\" target=\"_blank\" rel=\"noopener\">Estimating the risk of SARS-CoV-2 transmission to anesthesiologists: a microsimulation model. Canadian Journal of Anesthesia Journal Canadien d&#8217;anestheesie<\/a><\/span>. 67: 1694\u20131696.<\/li>\n<\/ul>\n<ul>\n<li>Heath, A., Kunst, N., Jackson, C., Strong, M., Alarid-Escudero, F., Goldhaber- Fiebert, J., Baio, G., Menzies, N., and Jalal, H. (2020). <span style=\"text-decoration: underline\"><a href=\"https:\/\/doi.org\/10.1177\/0272989X20912402\" target=\"_blank\" rel=\"noopener\">Calculating the Expected Value of Sample Information in Practice: Considerations from 3 Case Studies<\/a><\/span>. <em>Medical Decision Making<\/em>. 40(3): 314-326.<\/li>\n<\/ul>\n<ul>\n<li>Ali, S., Rajagopal, M., Richer, L., McCabe, C., Willan, A., Yaskina, M., Heath, A., Drendel, A., Gouin, S., Stang, A., Sawyer, S., Bhatt, M., Hickes, S., and Poonai, N., on behalf of the iPCT-PERC No OUCH Trials Team. (2020). <span style=\"text-decoration: underline\"><a href=\"\/\/dx.doi.org\/10.1136\/bmjopen-2019-035177\" target=\"_blank\" rel=\"noopener\">A study protocol for two complementary trials of non-steroidal or opioid analgesia use for children with musculoskeletal injuries (the No OUCH trials)<\/a><\/span>. B<em>MJ Open<\/em>. 10(6): e035177.<\/li>\n<\/ul>\n<ul>\n<li>Heath, A., Rios, J., Williamson-Urquhart, S. Pechlivanoglou, P., Offringa, M., McCabe, C., Hopkin, G., Plint, A., Dixon, A., Beer, D., Gouin, S., Joubert, G., Klassen, T., Freedman, S., on behalf of the PERCKIDSCAN DOSE-AGE Study Group. (2020). <span style=\"text-decoration: underline\"><a href=\"http:\/\/dx.doi.org\/https:\/\/doi.org\/10.1186\/s13063-020-04651-1\" target=\"_blank\" rel=\"noopener\">A Pragmatic Randomized Controlled Trial of Multi-Dose Oral Ondansetron for Pediatric Gastroenteritis (DOSE-AGE Study): A Statistical Analysis Plan<\/a><\/span>. <em>Trials<\/em>. 735(21): 1-8.<\/li>\n<\/ul>\n<\/div><\/div><\/div><\/div><\/div><div class=\"fusion-fullwidth fullwidth-box fusion-builder-row-5 fusion-flex-container nonhundred-percent-fullwidth non-hundred-percent-height-scrolling\" style=\"--awb-border-radius-top-left:0px;--awb-border-radius-top-right:0px;--awb-border-radius-bottom-right:0px;--awb-border-radius-bottom-left:0px;--awb-padding-top:20px;--awb-padding-left:10px;--awb-margin-bottom:30px;--awb-flex-wrap:wrap;\" ><div class=\"fusion-builder-row fusion-row fusion-flex-align-items-flex-start fusion-flex-content-wrap\" style=\"max-width:1248px;margin-left: calc(-4% \/ 2 );margin-right: calc(-4% \/ 2 );\"><div class=\"fusion-layout-column fusion_builder_column fusion-builder-column-5 fusion_builder_column_1_1 1_1 fusion-flex-column\" style=\"--awb-padding-left:20px;--awb-bg-size:cover;--awb-border-color:#0046ad;--awb-border-top:0px;--awb-border-right:0px;--awb-border-bottom:0px;--awb-border-left:5px;--awb-border-style:solid;--awb-width-large:100%;--awb-margin-top-large:0px;--awb-spacing-right-large:1.92%;--awb-margin-bottom-large:20px;--awb-spacing-left-large:0%;--awb-width-medium:100%;--awb-order-medium:0;--awb-spacing-right-medium:1.92%;--awb-spacing-left-medium:0%;--awb-width-small:100%;--awb-order-small:0;--awb-spacing-right-small:1.92%;--awb-spacing-left-small:1.92%;\"><div class=\"fusion-column-wrapper fusion-column-has-shadow fusion-flex-justify-content-flex-start fusion-content-layout-column\"><div class=\"fusion-text fusion-text-7\"><h2>2019<\/h2>\n<ul>\n<li>Heath, A., Manolopoulou, I., Baio, G. (2019). <span style=\"text-decoration: underline\"><a href=\"http:\/\/dx.doi.org\/https:\/\/doi.org\/10.1177\/0272989X19837983\" target=\"_blank\" rel=\"noopener\">Estimating the expected value of sample information across different sample sizes using moment matching and non-linear regression<\/a><\/span>. <em>Medical Decision Making<\/em>. 39(4): 346-358.<\/li>\n<\/ul>\n<\/div><\/div><\/div><\/div><\/div><div class=\"fusion-fullwidth fullwidth-box fusion-builder-row-6 fusion-flex-container nonhundred-percent-fullwidth non-hundred-percent-height-scrolling\" style=\"--awb-border-radius-top-left:0px;--awb-border-radius-top-right:0px;--awb-border-radius-bottom-right:0px;--awb-border-radius-bottom-left:0px;--awb-padding-top:20px;--awb-padding-left:10px;--awb-margin-bottom:30px;--awb-flex-wrap:wrap;\" ><div class=\"fusion-builder-row fusion-row fusion-flex-align-items-flex-start fusion-flex-content-wrap\" style=\"max-width:1248px;margin-left: calc(-4% \/ 2 );margin-right: calc(-4% \/ 2 );\"><div class=\"fusion-layout-column fusion_builder_column fusion-builder-column-6 fusion_builder_column_1_1 1_1 fusion-flex-column\" style=\"--awb-padding-left:20px;--awb-bg-size:cover;--awb-border-color:#0046ad;--awb-border-top:0px;--awb-border-right:0px;--awb-border-bottom:0px;--awb-border-left:5px;--awb-border-style:solid;--awb-width-large:100%;--awb-margin-top-large:0px;--awb-spacing-right-large:1.92%;--awb-margin-bottom-large:20px;--awb-spacing-left-large:0%;--awb-width-medium:100%;--awb-order-medium:0;--awb-spacing-right-medium:1.92%;--awb-spacing-left-medium:0%;--awb-width-small:100%;--awb-order-small:0;--awb-spacing-right-small:1.92%;--awb-spacing-left-small:1.92%;\"><div class=\"fusion-column-wrapper fusion-column-has-shadow fusion-flex-justify-content-flex-start fusion-content-layout-column\"><div class=\"fusion-text fusion-text-8\"><h2>2018<\/h2>\n<ul>\n<li>Heath, A., Manolopoulou, I., Baio, G. (2018). <a href=\"http:\/\/dx.doi.org\/10.1177\/0272989X17738515\" target=\"_blank\" rel=\"noopener\"><span style=\"text-decoration: underline\">Efficient Monte Carlo estimation of the expected value of sample information using moment matching<\/span>.<\/a> <em>Medical Decision Making<\/em>. 38(2): 163-173.<\/li>\n<\/ul>\n<ul>\n<li>Heath, A., Baio, G. (2018). <span style=\"text-decoration: underline\"><a href=\"http:\/\/dx.doi.org\/https:\/\/doi.org\/10.1016\/j.jval.2018.05.004\" target=\"_blank\" rel=\"noopener\">Calculating the expected value of sample information using efficient nested Monte Carlo: a tutorial<\/a><\/span>. <em>Value in Health<\/em>. 21(11): 1299-1304.<\/li>\n<\/ul>\n<\/div><\/div><\/div><\/div><\/div><div class=\"fusion-fullwidth fullwidth-box fusion-builder-row-7 fusion-flex-container nonhundred-percent-fullwidth non-hundred-percent-height-scrolling\" style=\"--awb-border-radius-top-left:0px;--awb-border-radius-top-right:0px;--awb-border-radius-bottom-right:0px;--awb-border-radius-bottom-left:0px;--awb-padding-top:20px;--awb-padding-left:10px;--awb-margin-bottom:30px;--awb-flex-wrap:wrap;\" ><div class=\"fusion-builder-row fusion-row fusion-flex-align-items-flex-start fusion-flex-content-wrap\" style=\"max-width:1248px;margin-left: calc(-4% \/ 2 );margin-right: calc(-4% \/ 2 );\"><div class=\"fusion-layout-column fusion_builder_column fusion-builder-column-7 fusion_builder_column_1_1 1_1 fusion-flex-column\" style=\"--awb-padding-left:20px;--awb-bg-size:cover;--awb-border-color:#0046ad;--awb-border-top:0px;--awb-border-right:0px;--awb-border-bottom:0px;--awb-border-left:5px;--awb-border-style:solid;--awb-width-large:100%;--awb-margin-top-large:0px;--awb-spacing-right-large:1.92%;--awb-margin-bottom-large:20px;--awb-spacing-left-large:0%;--awb-width-medium:100%;--awb-order-medium:0;--awb-spacing-right-medium:1.92%;--awb-spacing-left-medium:0%;--awb-width-small:100%;--awb-order-small:0;--awb-spacing-right-small:1.92%;--awb-spacing-left-small:1.92%;\"><div class=\"fusion-column-wrapper fusion-column-has-shadow fusion-flex-justify-content-flex-start fusion-content-layout-column\"><div class=\"fusion-text fusion-text-9\"><h2>2017<\/h2>\n<ul>\n<li>Baio, G.<strong>, <\/strong>Heath, A. (2017). <span style=\"text-decoration: underline\"><a href=\"http:\/\/dx.doi.org\/https:\/\/doi.org\/10.5301\/grhta.5000247\" target=\"_blank\" rel=\"noopener\">When simple becomes complicated: why Excel should lose its place at the top table<\/a><\/span>. <em>Global and Regional Health Technology Assessment<\/em>. 4(1): 3-6.<\/li>\n<\/ul>\n<ul>\n<li>Heath, A., Manolopoulou, I., Baio, G. (2017). <span style=\"text-decoration: underline\"><a href=\"http:\/\/dx.doi.org\/https:\/\/doi.org\/10.1177\/0272989X17697692\" target=\"_blank\" rel=\"noopener\">A review of methods for analysis of the expected value of information<\/a><\/span>. <em>Medical Decision Making<\/em>. 37(7): 747-758.<\/li>\n<\/ul>\n<\/div><\/div><\/div><\/div><\/div><div class=\"fusion-fullwidth fullwidth-box fusion-builder-row-8 fusion-flex-container nonhundred-percent-fullwidth non-hundred-percent-height-scrolling\" style=\"--awb-border-radius-top-left:0px;--awb-border-radius-top-right:0px;--awb-border-radius-bottom-right:0px;--awb-border-radius-bottom-left:0px;--awb-padding-top:20px;--awb-padding-left:10px;--awb-flex-wrap:wrap;\" ><div class=\"fusion-builder-row fusion-row fusion-flex-align-items-flex-start fusion-flex-content-wrap\" style=\"max-width:1248px;margin-left: calc(-4% \/ 2 );margin-right: calc(-4% \/ 2 );\"><div class=\"fusion-layout-column fusion_builder_column fusion-builder-column-8 fusion_builder_column_1_1 1_1 fusion-flex-column\" style=\"--awb-padding-left:20px;--awb-bg-size:cover;--awb-border-color:#0046ad;--awb-border-top:0px;--awb-border-right:0px;--awb-border-bottom:0px;--awb-border-left:5px;--awb-border-style:solid;--awb-width-large:100%;--awb-margin-top-large:0px;--awb-spacing-right-large:1.92%;--awb-margin-bottom-large:20px;--awb-spacing-left-large:0%;--awb-width-medium:100%;--awb-order-medium:0;--awb-spacing-right-medium:1.92%;--awb-spacing-left-medium:0%;--awb-width-small:100%;--awb-order-small:0;--awb-spacing-right-small:1.92%;--awb-spacing-left-small:1.92%;\"><div class=\"fusion-column-wrapper fusion-column-has-shadow fusion-flex-justify-content-flex-start fusion-content-layout-column\"><div class=\"fusion-text fusion-text-10\"><h2>2016<\/h2>\n<ul>\n<li>Heath, A., Manolopoulou, I., Baio, G. (2016). <span style=\"text-decoration: underline\"><a href=\"http:\/\/dx.doi.org\/10.1002\/sim.6983\" target=\"_blank\" rel=\"noopener\">Estimating the expected value of partial perfect information in health economic evaluations using integrated nested Laplace approximation<\/a><\/span>. <em>Statistics in Medicine<\/em>. 35: 4264\u20134280.<\/li>\n<\/ul>\n<\/div><\/div><\/div><\/div><\/div><\/p>\n","protected":false},"excerpt":{"rendered":"","protected":false},"author":338,"featured_media":0,"parent":0,"menu_order":0,"comment_status":"closed","ping_status":"closed","template":"","meta":{"footnotes":""},"class_list":["post-18","page","type-page","status-publish","hentry"],"yoast_head":"<!-- This site is optimized with the Yoast SEO Premium plugin v27.0 (Yoast SEO v27.0) - https:\/\/yoast.com\/product\/yoast-seo-premium-wordpress\/ -->\n<title>Publications - EMBaRC Lab<\/title>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/lab.research.sickkids.ca\/heath\/publications\/\" \/>\n<meta property=\"og:locale\" content=\"en_US\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"Publications\" \/>\n<meta property=\"og:url\" content=\"https:\/\/lab.research.sickkids.ca\/heath\/publications\/\" \/>\n<meta property=\"og:site_name\" content=\"EMBaRC Lab\" \/>\n<meta property=\"article:modified_time\" content=\"2025-04-08T18:29:00+00:00\" \/>\n<meta name=\"twitter:card\" content=\"summary_large_image\" \/>\n<meta name=\"twitter:label1\" content=\"Est. reading time\" \/>\n\t<meta name=\"twitter:data1\" content=\"34 minutes\" \/>\n<script type=\"application\/ld+json\" class=\"yoast-schema-graph\">{\"@context\":\"https:\/\/schema.org\",\"@graph\":[{\"@type\":\"WebPage\",\"@id\":\"https:\/\/lab.research.sickkids.ca\/heath\/publications\/\",\"url\":\"https:\/\/lab.research.sickkids.ca\/heath\/publications\/\",\"name\":\"Publications - 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