Research papers
- Wei Y*, Qin Q*, Hayes MN, Yan C, Xi H, Garcia S, Do D, Jin A, Eng T, Spentzos D, Neilsen P, Wexler L, Pyle AD, Suva M, Dela Cruz F, Pinello L, Langenau DM. Stem cell programs and developmental origins of rhabdomyosarcoma. Nature Cancer – 3(8): 961-975.
- Yan C, Brunson DC, Tang Q, Do D, Iftimia NA, Moore JC, Hayes MN, Welker AM, Garcia EG, Dubash T, Hong X, Drapkin BJ, Myers DT, Phat S, Volorio A, Marvin DL, Ligorio M, Dershowitz L, McCarthy KM, Karabacak M, Fletcher JA, Sgroi D, Iafrate AJ, Maheswaran S, Dyson NJ , Haber DA, 6, Rawls JF, Langenau DM. Visualizing engrafted human cancer and therapy responses in immun0deficient zebrafish. Cell. 2019 June 13; 177(7):1903-1914.
- Hayes MN*, Ignatius MS*, Moore FE, Tang Q, Garcia SP, Blackburn PR, Baxi K, Wang L, Jin A, Ramakrishnan A, Reeder S, Chen Y, Nielsen GP, Chen EY, Hasserjian RP, Ekker SC, Langenau DM. tp53 deficiency causes a wide tumour spectrum and elevates embryonal rhabdomyosarcoma metastasis in zebrafish. Elife. 2018. 7:e37202. *co-first author.
- Hayes MN, McCarthy K, Jin A, Oliveira ML, Iyer S, Garcia SP, Sindiri S, Gryder B, Motala Z, Nielsen GP, Borg JP, van de Rijn M, Malkin D, Khan J, Ignatius MS, Langenau DM. Vangl2/RhoA Signaling Pathway Regulates Stem Cell Self-Renewal Programs and Growth in Rhabdomyosarcoma. Cell Stem Cell. 2018 Mar 1;22(3):414-427.
- Ignatius MS, Hayes MN, Lobbardi R, Chen EY, McCarthy KM, Sreenivas P, Motala Z, Durbin AD, Molodtsov A, Reeder S, Jin A, Sindiri S, Beleyea BC, Bhere D, Alexander MS, Shah K, Keller C, Linardic CM, Nielsen PG, Malkin D, Khan J, Langenau DM. The NOTCH1/SNAIL1/MEF2C Pathway Regulates Growth and Self-Renewal in Embryonal Rhabdomyosarcoma. Cell Reports. 2017 Jun 13;19(11):2304-2318.
- Tenente IM, Hayes MN, Ignatius MS, McCarthy K, Yohe M, Sindiri S, Gryder B, Oliveira ML, Ramakrishnan A, Tang Q, Chen EY, Petur Nielsen G, Khan J, Langenau DM. Myogenic regulatory transcription factors regulate growth in rhabdomyosarcoma. Elife. 2017 Jan 12;6. pii: e19214.
- Tang Q, Moore JC, Ignatius MS, Tenente IM, Hayes MN, Garcia EG, Torres Yordán N, Bourque C, He S, Blackburn JS, Look AT, Houvras Y, Langenau DM. Imaging tumour cell heterogeneity following cell transplantation into optically clear immune-deficient zebrafish. Nature Communications. 2016 Jan 21;7:10358.
- Hayes M, Gao X, Yu LX, Paria N, Henkelman RM, Wise CA, Ciruna B. ptk7 mutant zebrafish models of congenital and idiopathic scoliosis implicate dysregulated Wnt signalling in disease. Nature Communications. 2014 Sep 3;5:4777.
- Hayes M, Naito M, Daulat A, Angers S, Ciruna B. Ptk7 promotes non-canonical Wnt/PCP-mediated morphogenesis and inhibits Wnt/b-catenin-dependent cell fate decisions during vertebrate development. Development. 2013 Apr;140(8):1807-18.
Reviews & chapters
- Yohe ME, Heske CM, Stewart E, Adamson PC, Ahmed N, Antonescu CR, Chen E, Collins N, Ehrlich A, Galindo RL, Gryder BE, Hahn H, Hammond S, Hatley ME, Hawkins DS, Hayes MN, Hayes-Jordan A, Helman LJ, Hettmer S, Ignatius MS, Keller C, Khan J, Kirsch DG, Linardic CM, Lupo PJ, Rota R, Shern JF, Shipley J, Sindiri S, Skapek SX, Tapscott SJ, Vakoc CR, Wexler LH, Langenau DM. Insights into rhabdomyosarcoma research: challenges and goals. Pediatric Blood and Cancer. 2019. Jun 21:e27869.
- Hayes MN, Langenau DM. Discovering novel oncogenic pathways and new therapies using zebrafish models of sarcoma. Methods in Cell Biology. 2017;138:525-561.
- Ignatius MS, Hayes M, Langenau DM. In Vivo Imaging of Cancer in Zebrafish. Advances in Experimental Medicine and Biology. 2016;916:219-37.