{"id":683,"date":"2015-09-16T14:59:56","date_gmt":"2015-09-16T14:59:56","guid":{"rendered":"https:\/\/lab.research.sickkids.ca\/harrison\/?page_id=683"},"modified":"2016-12-20T15:13:26","modified_gmt":"2016-12-20T15:13:26","slug":"cytomeglovirus-cmv-infection-study","status":"publish","type":"page","link":"https:\/\/lab.research.sickkids.ca\/harrison\/research\/cytomeglovirus-cmv-infection-study\/","title":{"rendered":"Cytomegalovirus (CMV) infection study"},"content":{"rendered":"

Balb\/C mice are\u00a0inoculated 3 days postnatally <\/span>with murine cytomegalovirus in the <\/span>(right) intra-cerebral with an\u00a0injection (2000 pfu in 1 ul).<\/span><\/strong><\/p>\n

At 4 weeks, auditory function was\u00a0tested <\/span>with ABR and OAE measurements.<\/span><\/strong><\/p>\n

At 8 weeks, vascular damage was evaluated using <\/span>partial corrosion cast and SEM microscopy.<\/span><\/strong><\/p>\n<\/div>

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\"Picture<\/a><\/span><\/div><\/div>
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Results<\/strong><\/h3><\/div>
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CMV infection causes significant <\/b>cochlear dysfunction<\/b><\/span><\/h1>\n<\/div>
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CMV damages mid to apical <\/span><\/strong>turn first<\/span><\/strong><\/h1>\n<\/div>
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\"ABR<\/a><\/span><\/div><\/div>
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\"difference<\/a><\/span><\/div><\/div>
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<\/p>\n\t\t\t\n\t\t\t\t\n\t\t\t\t\t\n\t\t\t\t\t\t\n\t\t\t\t\t\t\t\"CMV\n\"black \n\t\t\t\t\t\t\t<\/rs-layer>\"\" \n\t\t\t\t\t\t\t<\/rs-layer>\t\t\t\t\t<\/rs-slide>\n\t\t\t\t\t\t\n\t\t\t\t\t\t\t\"degenerated\n\"black \n\t\t\t\t\t\t\t<\/rs-layer>\"\" \n\t\t\t\t\t\t\t<\/rs-layer>\"\" \n\t\t\t\t\t\t\t<\/rs-layer>\t\t\t\t\t<\/rs-slide>\n\t\t\t\t\t\t\n\t\t\t\t\t\t\t\"Missing\n\"black \n\t\t\t\t\t\t\t<\/rs-layer>\"\" \n\t\t\t\t\t\t\t<\/rs-layer>\"\" \n\t\t\t\t\t\t\t<\/rs-layer>\t\t\t\t\t<\/rs-slide>\n\t\t\t\t\t<\/rs-slides>\n\t\t\t\t<\/rs-module>\n\t\t\t\t