{"id":19,"date":"2020-11-24T21:12:39","date_gmt":"2020-11-24T21:12:39","guid":{"rendered":"https:\/\/lab.research.sickkids.ca\/goldenberg\/?page_id=19"},"modified":"2024-06-20T12:51:46","modified_gmt":"2024-06-20T12:51:46","slug":"publications","status":"publish","type":"page","link":"https:\/\/lab.research.sickkids.ca\/goldenberg\/publications\/","title":{"rendered":"Publications"},"content":{"rendered":"\t\t
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Publications<\/h1>\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t
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For up to date bibliography please Click Here.<\/a><\/span>\u00a0<\/h4>

2024<\/h2>

Chin K, Jiang H, Steinberg BE, Goldenberg NM<\/b>, Desjardins JF, Kabir G, Liu E, Vanama R, Baker AJ, Deschamps A, Simpson JA, Maynes JT, Vinogradov SA, Connelly KA, Mazer CD, Hare GMT.\u00a0Bilateral nephrectomy impairs cardiovascular function and cerebral perfusion in a rat model of acute hemodilutional anemia<\/a>.\u00a0J Appl Physiol<\/em>. 2024 May 1;136(5):1245-1259.<\/p>

Wang DS, Ju L, Pinguelo AG, Kaneshwaran K, Haffey SC, Lecker I, Gohil H, Wheeler MB, Kaustov L, Ariza A, Yu M, Volchuk A, Steinberg BE, Goldenberg NM<\/b>, Orser BA.\u00a0Crosstalk between GABAA receptors in astrocytes and neurons triggered by general anesthetic drugs<\/a>.\u00a0Trans Res<\/em>. 2024 May:267:39-53.<\/p>

2023<\/h2>

Kayagaki N, Stowe IB, Alegre K, Deshpande I, Wu S, Lin Z, Kornfeld OS, Lee BL, Zhang J, Liu J, Suto E, Lee WP, Schneider K, Lin W, Seshasayee D, Bhangale T, Chalouni C, Johnson MC, Joshi P, Mossemann J, Zhao S, Ali D, Goldenberg NM<\/b>, Sayed BA, Steinberg BE, Newton K, Webster JD, Kelly RL, Dixit VM.\u00a0Inhibiting membrane rupture with NINJ1 antibodies limits tissue injury<\/a>.\u00a0Nature<\/em> 2023 Jun;618(7967):1072-1077.<\/p>

Foley AE, Sulstarova S, Goldenberg NM.\u00a0Assessment of HMGB1 Release During Experimentally Induced Pyroptosis<\/a>.\u00a0<\/b>Methods Mol<\/em>\u00a0Biol. 2023:2641:189-202.<\/p>

2022<\/h2>

Borges JP, S\u00e6tra RSR, Volchuk A, Bugge M, Devant P, Sporsheim B, Kilburn BR, Evavold CL, Kagan JC, Goldenberg NM<\/b>, Flo TH, Steinberg BE.\u00a0Glycine inhibits NINJ1 membrane clustering to suppress plasma membrane rupture in cell death<\/a>.\u00a0eLife<\/em> 2022 Dec 5:11:e78609.\u00a0<\/p>

McVey MJ, Maishan M, Foley A, Turki R, Roach EJ, Deschler R, Weidenfeld S, Goldenberg NM<\/b>, Khursigara CM, Kuebler WM.\u00a0Pseudomonas aeruginosa membrane vesicles cause endothelial barrier failure and lung injury<\/a>.\u00a0Eur Resp J<\/i>. 2022 <\/span>59: <\/span>2101500.<\/span><\/p>

Foley A, Steinberg BE,\u00a0Goldenberg NM<\/strong>.\u00a0Inflammasome Activation in Pulmonary Arterial Hypertension<\/a>.\u00a0Front Med.\u00a0<\/em>2022 Jan 13:8:826557.<\/p>

2021<\/h2>

Gai N, Aoyama K, Faraoni D,\u00a0Goldenberg NM<\/span>, Levin DN, Mayne JT, McVey MJ, Munshey F, Siddiqui A, Switzer T, Steinberg BE.\u00a0<\/p>

General medical publications during COVID-19 show increased dissemination despite lower validation<\/a>.<\/span>\u00a0PLoS One<\/span>. 16(2):e0246427 (2021).<\/p>

2020<\/h2>

McVey MJ, Steinberg BE, Goldenberg NM.<\/b> Inflammasome activation in acute lung injury.<\/a><\/span>\u00a0Am J Physiol Lung Cell Mol Physiol<\/em> 320(2):L165-L178 (2020).<\/p>

Hu Y, Chi L, Kuebler WM, Goldenberg NM. <\/b>Perivascular Inflammation in Pulmonary Arterial Hypertension.<\/span><\/a>\u00a0Cells<\/em> 9(11):2338 (2020).<\/p>

Ghaffari S, Jang E, Nabi FN, Sanwal R, Khosraviani N, Wang C, Steinberg BE, <\/span>Goldenberg NM<\/b>, Ikeda J, Lee WL. Endothelial HMGB1 is a critical regulator of LDL transcytosis via an SREBP2-SR-BI axis.<\/a> <\/span><\/span>Arterioscler Thromb Vasc Biol<\/span><\/i>. Oct. (2020).\u00a0<\/span><\/p>

Hu Y, Chi L, Kuebler WM, <\/span>Goldenberg NM. <\/b>Perivascular Inflammation in Pulmonary Arterial Hypertension.<\/span><\/a><\/span> Cells<\/span><\/i> 9<\/span><\/i>(11), 2338 (2020).\u00a0<\/span><\/p>

Volchuk A, Ye A, Chi L, Steinberg BE, <\/span>Goldenberg NM.<\/b> Indirect Regulation of HMGB1 Release By Gasdermin D.<\/span><\/a><\/span> Nature Communications<\/span><\/i> 11:4561 (2020).\u00a0<\/span><\/p>

Steinberg BE, Aoyama K, McVey M, Levin D, Siddiqui A, Munshey F, <\/span>Goldenberg NM<\/b>, Faraoni D, Maynes JT. Efficacy and safety of decontamination for N95 respirator reuse: a systematic literature search and narrative synthesis.<\/a> <\/span><\/span>Can J Anesth.<\/span><\/i> Jul 27:1-10 (2020).<\/span><\/p>

2019<\/h2>

Ali U,<\/span>\u00a0Goldenberg N, <\/b>Foreman C, Crawford Lynn L, Honjo O, O’Leary J, Faraoni D. Association Between Cyanosis, Transfusion, and Thrombotic Complications in Neonates and Children Undergoing Cardiac Surgery.<\/a><\/span>\u00a0<\/span>J Cardiothoracic Vasc Anesth<\/span><\/i>. 2019 July 13.<\/span><\/p>

Fergusson DA, Avey MT, Barron CC et al. Reporting preclinical anesthesia study (REPEAT): Evaluating the quality of reporting in the preclinical anesthesiology literature.<\/a> <\/span><\/span>PLoS One<\/span><\/i>. 2019 May 23.<\/span><\/p>

Goldenberg NM<\/b>, Rabinovitch M, Steinberg BE. The inflammatory basis of pulmonary arterial hypertension: Clinical implications.<\/a> <\/span><\/span>Anesthesiology<\/span><\/i>. 131(4)898-907 (2019).\u00a0<\/span><\/p>

Goldenberg NM, <\/b>Hu Y, Hu X, Volchuk A, Zhao YD, Kucherenko MM, Knosalla C, de Perrot M, Tracey KJ, Al-Abed Y, Steinberg BE, Kuebler WM. Therapeutic targeting of high mobility group box-1 in pulmonary arterial hypertension.<\/a> <\/span><\/span>Am J Resp Crit Care Med<\/span><\/i>. 199(12):1566-1569 (2019).\u00a0<\/span><\/p>

Goldenberg NM<\/b> and Steinberg BE. Inflammation drives pulmonary arterial hypertension.<\/a><\/span>\u00a0 <\/span>Anesthesiology<\/span><\/i>. 130(5):820-821 (2019).\u00a0<\/span><\/p>

2018<\/h2>

Sugiyama MG, Raheel H, Mintsopoulos V, <\/span>Goldenberg <\/b>NM, et al. Lung ultrasound and microbubbles enhance aminoglycoside efficacy in the lung in E. coli-induced pneumonia and ARDS.<\/a><\/span>\u00a0<\/span>Am J Resp Crit Care Med. <\/span><\/i>198(3):404-408. (2018).\u00a0<\/span><\/p>

Hu Y, Zabini D, Gu W, Breitling S, <\/span>Goldenberg NM<\/b>, Kabir G, Connelly K, Kuebler WM.\u00a0 The role of the human immune system in chronic hypoxic pulmonary hypertension.<\/a><\/span> \u00a0 <\/span>Am J Resp Crit Care Med.<\/span><\/i> 198(4):528-531 (2018).<\/span><\/p>

2017<\/h2>

Breitling S, Zhang H, Zabini D, Hu Y, Hoffmann J, <\/span>Goldenberg NM<\/b>, Buelow R, Kuebler WM.\u00a0 The mast cell – B-cell axis in lung vascular remodeling and pulmonary hypertension.<\/a><\/span>\u00a0 <\/span>Am J Physiol \u2013 Lung.\u00a0 <\/span><\/i>312(5):L710-L721 (2017)<\/span><\/p>

2016<\/h2>

Goldenberg NM<\/b>, Steinberg BE, Rutka JT, Chen R, Cabral V, Rosenblum ND, Kapus A, Lee WL.\u00a0 Research projects in the Surgeon-Scientist and Clinician-Investigator programs at the University of Toronto (1987-2016): A cohort study.<\/a><\/span>\u00a0 <\/span>CMAJ Open<\/span><\/i>.\u00a0 4(3):E444-E447 (2016)<\/span><\/p>

Kuebler WM, Wittenberg C, Lee WL, Reppien E, <\/span>Goldenberg NM<\/b>, Lindner K, Gao Y, Winoto-Morbach S, Drab M, Mu\u0308hlfeld C, Dombrowsky H, Ochs M, Schu\u0308tze S, Uhlig S. Thrombin stimulates albumin transcytosis in lung microvascular endothelial cells via activation of acid sphingomyelinase.<\/a><\/span>\u00a0 <\/span>Am J Physiol \u2013 Lung<\/span><\/i>. 310(8):L720-L732 (2016)<\/span><\/p>

Yin J, Michalick L, Tang CT, Tabuchi A, <\/span>Goldenberg NM<\/b>, Dan Q, Awwad K, Wang L, Erfinanda L, Nouailles-Kursar G, Witzenrath M, Vogelzang A, Lv L, Lee WL, Zhang H, Rotstein O, Kapus A, Szaszi K, Fleming I, Liedtke W, Kuppe H, Kuebler WM<\/span>.<\/span><\/i> Role of transient receptor potential vanilloid 4 in neutrophil activation and acute lung injury.<\/a><\/span>\u00a0 <\/span>Am J Resp Cell Mol Biol<\/span><\/i>.\u00a0 54(3):370-83 (2016).<\/span><\/p>

Steinberg BE, <\/span>Goldenberg NM<\/b>, Fairn GD, Kuebler WM, Slutsky AS, Lee WL.\u00a0 Is basic science disappearing from medicine? The decline of biomedical research in the medical literature.<\/a> <\/span><\/span>FASEB J<\/span><\/i>. 30(2):515-528 (2016)<\/span><\/p>

2015<\/h2>

Breitling S, Ravindran K, <\/span>Goldenberg NM<\/b>, Kuebler WM.\u00a0 The Pathophysiology of Pulmonary Hypertension in Left Heart Disease.<\/a><\/span>\u00a0 <\/span>Am J Physiol \u2013 Lung<\/span><\/i>. 309(9):L924-41 (2015).<\/span><\/p>

Steinberg BE, <\/span>Goldenberg NM<\/b>, Laffey JG.\u00a0 Extracorporeal membrane oxygenation for blastomycosis-related severe ARDS: a new indication as a rescue therapy?<\/a><\/span>\u00a0 <\/span>Can J Anesth.<\/span><\/i>\u00a0 Apr. 16 (2015).<\/span><\/p>

Tabeling C, Yu H, Wang L, Ranke H, <\/span>Goldenberg NM<\/b>, Zabini\u00a0 D, Noe E, Krauszman A, Gutbier B, Yin J, Schaefer M, Arenz C, Hocke AC, Suttorp N, Proia RL, Witzenrath M, Kuebler WM.\u00a0 CFTR and sphingolipids mediate hypoxic pulmonary vasoconstriction.<\/a><\/span>\u00a0 <\/span>Proc Nat Acad Sci<\/span><\/i>. 112(13):E1614-23 (2015).\u00a0<\/span><\/p>

Goldenberg NM, <\/b>Steinberg BE, Wijeysundera D, Kavanagh BP.\u00a0 In Reply.<\/a>\u00a0 <\/span><\/span>Anesthesiology<\/span><\/i>. 122(2):473 (2015).\u00a0<\/span><\/p>

Goldenberg NM, <\/b>Wang L, Ranke H, Tabuchi A, Liedtke W, Kuebler WM.\u00a0 TRPV4 is required for hypoxic pulmonary vasoconstriction.<\/span> <\/a><\/span>Anesthesiology <\/span><\/i>122(6):1338-48 (2015).\u00a0<\/span><\/p>

Goldenberg NM, <\/b>Ravindran K, Kuebler WM.\u00a0 TRPV4: Physiological role and therapeutic potential in respiratory diseases.<\/a><\/span>\u00a0 <\/span>Naunyn Schmiedeberg Arch Pharmacol.\u00a0 <\/span><\/i>388(4):421 (2015).<\/span><\/p>

Goldenberg NM <\/b>and Kuebler WM.\u00a0 Endothelial Cell Regulation of Pulmonary Vascular Tone, Inflammation, and Coagulation.<\/a> <\/span><\/span>Comprehensive Physiology.<\/span><\/i>5(2):532 (2015).<\/span><\/p>

2014-<\/h2>

Goldenberg NM<\/b>, Leligdowicz A, Slutsky AS, Friedrich JO, Lee WL. Is Nosocomial Infection Really the Major Cause of Death in Sepsis?<\/a><\/span>\u00a0 <\/span>Crit Care<\/span><\/i>.\u00a0 18(5):540 (2014).<\/span><\/p>

Goldenberg NM, <\/b>Steinberg BE, Wijeysundera D, Kavanagh BP.\u00a0 Lung Protective Ventilation in the Operating Room: Time to Implement?<\/a><\/span>\u00a0 <\/span>Anesthesiology<\/span><\/i>.\u00a0 121(1):184-8 (2014).\u00a0<\/span><\/p>

Goldenberg NM, <\/b>Hare GM.\u00a0 From the Journal archives: Understanding the mechanism(s) regulating hypoxic pulmonary vasoconstriction: how an early study has led to novel translational approaches.<\/a><\/span>\u00a0 <\/span>Can J Anesth.<\/span><\/i>\u00a0 62(2):195-9 (2014).<\/span><\/p>

Steinberg BE, <\/span>Goldenberg NM<\/b>, Lee WL. Do viral infections mimic bacterial sepsis? The role of microvascular permeability: A review of mechanisms and methods.<\/a><\/span><\/span> \u00a0<\/span>Antiviral Research <\/span><\/i>93(1):2-15 (2012).<\/span><\/p>

Goldenberg NM<\/b>, Steinberg BE, Slutsky AS, Lee WL.\u00a0 Broken Barriers:\u00a0 A New Take On Sepsis Pathogenesis.<\/a><\/span>\u00a0 <\/span>Sci. Transl. Med.<\/span><\/i> 3, 86ps22 (2011).\u00a0<\/span><\/p>

Goldenberg NM<\/b>, Steinberg BE.\u00a0 Surface Charge:\u00a0 A key determinant of protein localization and function.<\/a><\/span>\u00a0 <\/span>Cancer Res.\u00a0 <\/span><\/i>70(4):1277-80 (2010).\u00a0<\/span><\/p>

Goldenberg NM<\/b>, Silverman M. Rab34 and its effector munc13-2 constitute a new pathway modulating protein secretion in the cellular response to hyperglycemia.<\/a><\/span>\u00a0 <\/span>Am J Physiol Cell Physiol.<\/span><\/i>\u00a0 297(4):C1053-8 (2009).<\/span><\/p>

Plant PJ, Correa J, <\/span>Goldenberg N<\/b>, Bain J, Batt J.\u00a0 The inositol phosphatase MTMR4 is a novel target of the ubiquitin ligase NEDD4.<\/a><\/span>\u00a0 <\/span>Biochem J.<\/span><\/i>\u00a0 419(1):57-63 (2009).<\/span><\/p>

Goldenberg NM<\/b>, Grinstein S, Silverman M.\u00a0 Golgi-bound Rab34 is a novel member of the secretory pathway.<\/a><\/span>\u00a0 <\/span>Mol Biol Cell<\/span><\/i>.\u00a0 8(12):4762-4771 (2007).<\/span><\/p>

Ailenberg M, <\/span>Goldenberg NM, <\/b>Silverman M.\u00a0 Description of a PCR-based technique for DNA splicing and mutagenesis by producing 5\u2019 overhangs with run through stop DNA synthesis utilizing Ara-C.<\/a><\/span>\u00a0 <\/span>BMC Biotechnol.\u00a0 <\/span><\/i>5:23 (2005).<\/span><\/p>\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t

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Publications For up to date bibliography please Click Here.\u00a0 2024 Chin K, Jiang H, Steinberg BE, Goldenberg NM, Desjardins JF, Kabir G, Liu E, Vanama R, Baker AJ, Deschamps A, Simpson JA, Maynes JT, Vinogradov SA, Connelly KA, Mazer CD, Hare GMT.\u00a0Bilateral nephrectomy impairs cardiovascular function and cerebral perfusion in a rat model of acute…<\/p>\n","protected":false},"author":293,"featured_media":0,"parent":0,"menu_order":3,"comment_status":"closed","ping_status":"closed","template":"","meta":{"footnotes":""},"class_list":["post-19","page","type-page","status-publish","hentry"],"yoast_head":"\nPublications - Goldenberg Lab<\/title>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/lab.research.sickkids.ca\/goldenberg\/publications\/\" \/>\n<meta property=\"og:locale\" content=\"en_US\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"Publications\" \/>\n<meta property=\"og:description\" content=\"Publications For up to date bibliography please Click Here.\u00a0 2024 Chin K, Jiang H, Steinberg BE, Goldenberg NM, Desjardins JF, Kabir G, Liu E, Vanama R, Baker AJ, Deschamps A, Simpson JA, Maynes JT, Vinogradov SA, Connelly KA, Mazer CD, Hare GMT.\u00a0Bilateral nephrectomy impairs cardiovascular function and cerebral perfusion in a rat model of acute…\" \/>\n<meta property=\"og:url\" content=\"https:\/\/lab.research.sickkids.ca\/goldenberg\/publications\/\" \/>\n<meta property=\"og:site_name\" content=\"Goldenberg Lab\" \/>\n<meta property=\"article:modified_time\" content=\"2024-06-20T12:51:46+00:00\" \/>\n<meta name=\"twitter:card\" content=\"summary_large_image\" \/>\n<meta name=\"twitter:label1\" content=\"Est. reading time\" \/>\n\t<meta name=\"twitter:data1\" content=\"6 minutes\" \/>\n<script type=\"application\/ld+json\" class=\"yoast-schema-graph\">{\"@context\":\"https:\/\/schema.org\",\"@graph\":[{\"@type\":\"WebPage\",\"@id\":\"https:\/\/lab.research.sickkids.ca\/goldenberg\/publications\/\",\"url\":\"https:\/\/lab.research.sickkids.ca\/goldenberg\/publications\/\",\"name\":\"Publications - 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