{"id":1211,"date":"2022-03-16T14:47:09","date_gmt":"2022-03-16T14:47:09","guid":{"rendered":"https:\/\/lab.research.sickkids.ca\/enrich\/?page_id=1211"},"modified":"2026-02-06T19:54:15","modified_gmt":"2026-02-06T19:54:15","slug":"covid-19-knowledge-translation","status":"publish","type":"page","link":"https:\/\/lab.research.sickkids.ca\/enrich\/knowledge-translation\/covid-19-knowledge-translation\/","title":{"rendered":"COVID-19 Knowledge Translation"},"content":{"rendered":"<h1><span style=\"color: #000000\"><strong>Knowledge mobilization activities to support decision-making by youth using a systematic and living map of evidence and recommendations on COVID-19<\/strong><\/span><\/h1>\n<p>&nbsp;<\/p>\n<p><span style=\"color: #000000\">As the general public is overwhelmed with information about COVID-19, including misinformation, a unique repository of COVID-19 guidelines (called the <span style=\"color: #64a0c8\"><a style=\"color: #64a0c8\" href=\"https:\/\/covid19.recmap.org\/\">RecMap<\/a><\/span>) was developed by McMaster University with funding from <span style=\"color: #64a0c8\"><a style=\"color: #64a0c8\" href=\"https:\/\/cihr-irsc.gc.ca\/e\/193.html\">CIHR<\/a>.<\/span> The goal of the RecMap is to identify all COVID-19 guidelines, assess their credibility, and make them accessible to the general public.<\/span><\/p>\n<p><span style=\"color: #000000\">COVID-19 guidelines are commonly developed for healthcare professionals; yet, these guidelines must be accessible and easy for the general public to understand. Led by McMaster, <strong>Plain Language Versions<\/strong> of <strong>COVID-19 Recommendations (PLRs)<\/strong> have been developed to support youth, parents, and adults as autonomous decision-makers regarding their health and to improve their health outcomes. The understandability and acceptability of these PLRs are now being investigated in a CIHR funded multi-center trial.<\/span><\/p>\n<p><span style=\"color: #000000\"><span style=\"color: #64a0c8\"><a style=\"color: #64a0c8\" href=\"https:\/\/lab.research.sickkids.ca\/enrich\/\">EnRICH<\/a><\/span>\u00a0 lead the youth site (Principal Investigators: Drs. Nancy Butcher and Martin Offringa) and recruited young people ages 15-24 globally. EnRICH has refined the PLRs for youth and will test this format during the trial.<\/span><\/p>\n<p><span style=\"color: #000000\"><strong>Youth Partnership and Engagement<\/strong><\/span><\/p>\n<p><span style=\"color: #000000\">Because young people are end users of COVID-19 PLRs, it is critical that they are meaningfully engaged throughout the research process to ensure that their lived experiences are captured. We have partnered with two youth facilitators, Matthew Prebeg and Jacqueline Relihan from the <span style=\"color: #64a0c8\"><a style=\"color: #64a0c8\" href=\"https:\/\/www.camh.ca\/\">Centre for Addiction and Mental Health<\/a><\/span> in Toronto, Ontario. Through this partnership, we co-developed and implemented pre-trial engagement work with Canadian youth advisors, whereby we created study materials, refined a PLR format based on youth preferences, and ensured meaningful engagement efforts were embedded throughout the research process.<\/span><\/p>\n<p><span style=\"color: #000000\"><strong>Our Objective<\/strong><\/span><\/p>\n<p><span style=\"color: #000000\">Our site seeks to understand whether PLRs are easier for youth to use and understand in comparison to the original format, while still conveying the intended message from the original guideline.<\/span><\/p>\n<p><span style=\"color: #000000\"><strong>Collaborators and Partners<\/strong><\/span><\/p>\n<p><span style=\"color: #000000\"><a style=\"color: #000000\" href=\"https:\/\/lab.research.sickkids.ca\/enrich\/\"><span style=\"color: #64a0c8\">SickKids Research Institute<\/span><\/a> recruited youth, <a style=\"color: #000000\" href=\"https:\/\/www.ualberta.ca\/pediatrics\/pediatric-research\/affiliated-research-units\/alberta-research-centre-for-health-evidence-arche\/index.html\"><span style=\"color: #64a0c8\">The University of Alberta<\/span><\/a> recruited parents, and <a style=\"color: #000000\" href=\"https:\/\/uwo.ca\/research\/index.html\">Western University<\/a>\u00a0 recruited adults. All three sites were coordinated through <span style=\"color: #64a0c8\"><a style=\"color: #64a0c8\" href=\"https:\/\/hei.mcmaster.ca\/research\">McMaster University<\/a><\/span>, the lead site.<\/span><\/p>\n<p><span style=\"color: #000000\">All sites worked closely with an <strong>international team<\/strong> of recognized experts in knowledge synthesis, randomized trials, guidelines development, living recommendations, capacity-building, and content relevant to our specific priority populations. This collaborative effort represents teams in Canada, Norway, Australia, Brazil, Chile, Germany, India, Italy, Lebanon, Spain, South Africa, The Netherlands, United Kingdom, and United States.<\/span><\/p>\n<p><span style=\"color: #000000\">Our <strong>partners<\/strong> include <a style=\"color: #000000\" href=\"https:\/\/www.canada.ca\/en\/public-health.html\"><span style=\"color: #64a0c8\">The Public Health Agency of Canada<\/span><\/a>, <span style=\"color: #64a0c8\"><a style=\"color: #64a0c8\" href=\"https:\/\/www.cadth.ca\/\">The Canadian Agency for Drugs and Technology in Health<\/a><\/span>, <span style=\"color: #64a0c8\"><a style=\"color: #64a0c8\" href=\"https:\/\/www.inesss.qc.ca\/\">Institut national d\u2019excellence en sant\u00e9 et services sociaux<\/a><\/span>, <span style=\"color: #64a0c8\"><a style=\"color: #64a0c8\" href=\"https:\/\/www.fhi.no\/en\/\">The Norwegian Public Health Institute<\/a><\/span>, <a style=\"color: #000000\" href=\"https:\/\/www.euro.who.int\/en\"><span style=\"color: #64a0c8\">WHO European (EURO)<\/span>,<\/a> <span style=\"color: #64a0c8\"><a style=\"color: #64a0c8\" href=\"https:\/\/www.paho.org\/en\/countries-and-centers\">Pan-American (PAHO) regional offices<\/a><\/span>, <span style=\"color: #64a0c8\">Secretariat of the <a style=\"color: #64a0c8\" href=\"https:\/\/www.who.int\/groups\/expert-committee-on-selection-and-use-of-essential-medicines\/essential-medicines-lists\">WHO Model List of Essential Medicines<\/a><\/span>, <span style=\"color: #64a0c8\"><a style=\"color: #64a0c8\" href=\"https:\/\/epoc.cochrane.org\/news\/gesi#:~:text=The%20goal%20of%20the%20GESI,middle%20income%20countries%20(LMICs).\">The Global Evidence Synthesis Initiative<\/a><\/span>, <span style=\"color: #64a0c8\"><a style=\"color: #64a0c8\" href=\"https:\/\/g-i-n.net\/\">The Guidelines International Network (G-I-N)<\/a> <\/span>and Canadian-based and leading international institutions or organizations.<\/span><\/p>\n<p><span style=\"color: #000000\"><strong>Publications:<\/strong><\/span><\/p>\n<p><span style=\"color: #000000\">The trial protocol and three trial report manuscripts have been published.<\/span><\/p>\n<ul>\n<li><span style=\"color: #64a0c8\"><a style=\"color: #64a0c8\" href=\"https:\/\/trialsjournal.biomedcentral.com\/articles\/10.1186\/s13063-023-07067-9\">Trial protocol<\/a><\/span><\/li>\n<li><span style=\"color: #64a0c8\"><a style=\"color: #64a0c8\" href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/37548983\/\">Trial publication: Plain Language vs Standard Format for Youth Understanding of COVID-19 Recommendations: A Randomized Clinical Trial (JAMA Pediatrics)<\/a><\/span><\/li>\n<li><span style=\"color: #64a0c8\"><a style=\"color: #64a0c8\" href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/37421995\/\">Trial publication: A multimethods randomized trial found that plain language versions improved parents&#8217; understanding of health recommendations (Journal of Clinical Epidemiology)<\/a><\/span><\/li>\n<li><span style=\"color: #64a0c8\"><a style=\"color: #64a0c8\" href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/38008266\/\">Trial publication: A multimethods randomized trial found that plain language versions improved adults understanding of health recommendations (Journal of Clinical Epidemiology)<\/a><\/span><\/li>\n<\/ul>\n<p>&nbsp;<\/p>\n<p><span style=\"color: #000000\">Updated February 2026<\/span><\/p>\n<p>&nbsp;<\/p>\n","protected":false},"excerpt":{"rendered":"<p>Knowledge mobilization activities to support decision-making by youth using a  [&#8230;]<\/p>\n","protected":false},"author":241,"featured_media":0,"parent":613,"menu_order":0,"comment_status":"closed","ping_status":"closed","template":"","meta":{"footnotes":""},"class_list":["post-1211","page","type-page","status-publish","hentry"],"yoast_head":"<!-- This site is optimized with the Yoast SEO Premium plugin v27.0 (Yoast SEO v27.0) - 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