{"id":500,"date":"2015-01-12T18:50:57","date_gmt":"2015-01-12T18:50:57","guid":{"rendered":"http:\/\/lab-dev.research.sickkids.ca\/brent-derry-lab\/?page_id=500"},"modified":"2026-04-13T14:39:01","modified_gmt":"2026-04-13T14:39:01","slug":"meet-the-scientist","status":"publish","type":"page","link":"https:\/\/lab.research.sickkids.ca\/derry\/meet-the-scientist\/","title":{"rendered":"The Leader"},"content":{"rendered":"<p><div class=\"fusion-fullwidth fullwidth-box fusion-builder-row-1 nonhundred-percent-fullwidth non-hundred-percent-height-scrolling\" style=\"--awb-background-position:left top;--awb-border-sizes-top:0px;--awb-border-sizes-bottom:0px;--awb-border-sizes-left:0px;--awb-border-sizes-right:0px;--awb-border-radius-top-left:0px;--awb-border-radius-top-right:0px;--awb-border-radius-bottom-right:0px;--awb-border-radius-bottom-left:0px;--awb-padding-top:20px;--awb-padding-right:0px;--awb-padding-bottom:20px;--awb-padding-left:0px;--awb-flex-wrap:wrap;\" ><div class=\"fusion-builder-row fusion-row\"><div class=\"fusion-layout-column fusion_builder_column fusion-builder-column-0 fusion_builder_column_1_3 1_3 fusion-one-third fusion-column-first\" style=\"--awb-bg-size:cover;width:30.6666%; margin-right: 4%;\"><div class=\"fusion-column-wrapper fusion-flex-column-wrapper-legacy\"><div class=\"fusion-person person fusion-person-center fusion-person-1 fusion-person-icon-top\" style=\"--awb-pic-style-color:#4b4c4d;--awb-pic-borderradius:0px;--awb-margin-top:0px;--awb-margin-right:0px;--awb-margin-bottom:0px;--awb-margin-left:0px;--awb-social-box-border-top:0px;--awb-social-box-border-right:0px;--awb-social-box-border-bottom:0px;--awb-social-box-border-left:0px;--awb-social-box-border-color:var(--awb-color3);--awb-social-box-border-color-hover:var(--awb-color4);--awb-social-box-colors-hover:rgba(0,155,116,0.328);--awb-social-icon-boxed-colors:rgba(0,155,116,0.41);--awb-social-icon-colors:rgba(0,0,0,0.65);--awb-social-icon-colors-hover:rgba(0,0,0,0.52);\"><div class=\"person-shortcode-image-wrapper\"><div class=\"person-image-container hover-type-none\" style=\"border:0px solid #f6f6f6;-webkit-border-radius:0px;-moz-border-radius:0px;border-radius:0px;\"><img decoding=\"async\" class=\"person-img img-responsive wp-image-3127\" width=\"400\" height=\"400\" src=\"https:\/\/lab.research.sickkids.ca\/derry\/wp-content\/uploads\/sites\/11\/2018\/01\/Copy-of-Custom-\u2013-Untitled-Design.png\" srcset=\"https:\/\/lab.research.sickkids.ca\/derry\/wp-content\/uploads\/sites\/11\/2018\/01\/Copy-of-Custom-\u2013-Untitled-Design-200x200.png 200w, https:\/\/lab.research.sickkids.ca\/derry\/wp-content\/uploads\/sites\/11\/2018\/01\/Copy-of-Custom-\u2013-Untitled-Design.png 400w\" sizes=\"(max-width: 800px) 100vw, 400px\" \/><\/div><\/div><\/div><div class=\"fusion-sep-clear\"><\/div><div class=\"fusion-separator fusion-full-width-sep\" style=\"margin-left: auto;margin-right: auto;margin-top:15px;margin-bottom:15px;width:100%;\"><\/div><div class=\"fusion-sep-clear\"><\/div><div class=\"aligncenter\"><div class=\"fusion-social-links fusion-social-links-1\" style=\"--awb-margin-top:0px;--awb-margin-right:0px;--awb-margin-bottom:0px;--awb-margin-left:0px;--awb-alignment:center;--awb-box-border-top:0px;--awb-box-border-right:0px;--awb-box-border-bottom:0px;--awb-box-border-left:0px;--awb-icon-colors-hover:rgba(0,0,0,0.52);--awb-box-colors-hover:rgba(0,155,116,0.328);--awb-box-border-color:var(--awb-color3);--awb-box-border-color-hover:var(--awb-color4);\"><div class=\"fusion-social-networks boxed-icons color-type-custom\"><div class=\"fusion-social-networks-wrapper\"><a class=\"fusion-social-network-icon fusion-tooltip fusion-twitter awb-icon-twitter\" style=\"color:#231f20;font-size:16px;width:16px;background-color:rgba(0,155,116,0.56);border-color:rgba(0,155,116,0.56);border-radius:4px;\" data-placement=\"top\" data-title=\"X\" data-toggle=\"tooltip\" title=\"X\" aria-label=\"twitter\" target=\"_blank\" rel=\"noopener noreferrer\" href=\"https:\/\/twitter.com\/wbderry\"><\/a><a class=\"fusion-social-network-icon fusion-tooltip fusion-mail awb-icon-mail\" style=\"color:#231f20;font-size:16px;width:16px;background-color:rgba(0,155,116,0.56);border-color:rgba(0,155,116,0.56);border-radius:4px;\" data-placement=\"top\" data-title=\"Email\" data-toggle=\"tooltip\" title=\"Email\" aria-label=\"mail\" target=\"_blank\" rel=\"noopener noreferrer\" href=\"mailto:&#098;r&#101;&#110;&#116;&#046;de&#114;&#114;y&#064;&#115;ic&#107;&#107;id&#115;&#046;&#099;a\"><\/a><\/div><\/div><\/div><\/div><div class=\"fusion-clearfix\"><\/div><\/div><\/div><div class=\"fusion-layout-column fusion_builder_column fusion-builder-column-1 fusion_builder_column_2_3 2_3 fusion-two-third fusion-column-last\" style=\"--awb-bg-size:cover;width:65.3333%;\"><div class=\"fusion-column-wrapper fusion-flex-column-wrapper-legacy\"><div class=\"fusion-text fusion-text-1\"><h2 style=\"text-align: left\"><span style=\"color: #000000\">Brent Derry, PhD<\/span><\/h2>\n<\/div><div class=\"fusion-text fusion-text-2\"><h3><span style=\"color: #000000\">Education<\/span><\/h3>\n<p><span style=\"color: #000000\"><strong>PhD<\/strong>\u00a0| Biochemistry and Molecular Biology, University of California, Santa Barbara, California, USA<br \/>\n<strong style=\"line-height: 1.5\">M.Sc.<\/strong><span style=\"line-height: 1.5\"> | Biochemistry, McMaster University, Hamilton, Ontario, Canada<br \/>\n<\/span><strong style=\"line-height: 1.5\">B.Sc.<\/strong><span style=\"line-height: 1.5\"> | (Honours) Biochemistry, Carleton University, Ottawa, Ontario, Canada<\/span><\/span><\/p>\n<h3><span style=\"color: #000000\">Professional Experience<\/span><\/h3>\n<p><span style=\"color: #000000\"><strong>2023 &#8211; Present <\/strong>| Research Integrity Advisor, The Hospital for Sick Children<br \/>\n<\/span><span style=\"color: #000000\"><strong>2019 &#8211; Present <\/strong>| Canada Research Chair in Genetic models of human disease<br \/>\n<\/span><span style=\"color: #000000\"><strong>2016 &#8211; Present <\/strong>| Professor, Department of Molecular Genetics, University of Toronto<\/span><br \/>\n<span style=\"color: #000000\"><strong> 2015 &#8211; 2023 <\/strong>| Vice Chair of Fundamental Research, Garron Family Cancer Centre, <span style=\"line-height: 1.5\">The Hospital for Sick Children<\/span><br \/>\n<strong>2011 &#8211; 2016\u00a0<\/strong>|\u00a0Associate Professor, Department of Molecular Genetics, University of Toronto<br \/>\n<strong>2010 &#8211; Present<\/strong><span style=\"line-height: 1.5\"> | Senior Scientist, Developmental, Stem Cell &amp; Cancer Biology, The Hospital for Sick Children<br \/>\n<\/span><strong>2003 \u2013 2011<\/strong><span style=\"line-height: 1.5\"> |\u00a0Assistant Professor, Department of Molecular Genetics, University of Toronto<br \/>\n<\/span><strong>2003 &#8211; 2010 <\/strong>| Scientist, <span style=\"line-height: 1.5\">Developmental, Stem Cell &amp; Cancer Biology<\/span>, The Hospital for Sick Children<br \/>\n<strong>1997 &#8211; 2003<\/strong><span style=\"line-height: 1.5\"> |\u00a0Postdoctoral Fellow, University of California, Santa Barbara<\/span><\/span><\/p>\n<pre><\/pre>\n<h3><span style=\"color: #000000\">Research Interests<\/span><\/h3>\n<p><span style=\"color: #000000\">Life and Death&#8230;<\/span><\/p>\n<\/div><div class=\"fusion-alignleft\"><a class=\"fusion-button button-flat button-xlarge button-custom fusion-button-default button-1 fusion-button-default-span fusion-button-default-type fusion-has-button-gradient\" style=\"--button_bevel_color:rgba(35,31,32,0.88);--button_accent_color:#231f20;--button_border_color:#231f20;--button_accent_hover_color:#ffffff;--button_border_hover_color:#ffffff;--button_border_width-top:1px;--button_border_width-right:1px;--button_border_width-bottom:1px;--button_border_width-left:1px;--button_gradient_top_color:#ffffff;--button_gradient_bottom_color:#ffffff;--button_gradient_top_color_hover:rgba(0,155,116,0.56);--button_gradient_bottom_color_hover:rgba(0,155,116,0.21);\" target=\"_blank\" rel=\"noopener noreferrer\" href=\"https:\/\/lab.research.sickkids.ca\/derry\/wp-content\/uploads\/sites\/11\/2026\/04\/CCV-WilliamDerry-CIHR_Biosketch-March-26-2026.pdf\"><span class=\"fusion-button-text awb-button__text awb-button__text--default\">Download CV<\/span><\/a><\/div><div class=\"fusion-clearfix\"><\/div><\/div><\/div><\/div><\/div><div class=\"fusion-fullwidth fullwidth-box fusion-builder-row-2 nonhundred-percent-fullwidth non-hundred-percent-height-scrolling\" style=\"--awb-border-radius-top-left:0px;--awb-border-radius-top-right:0px;--awb-border-radius-bottom-right:0px;--awb-border-radius-bottom-left:0px;--awb-flex-wrap:wrap;\" ><div class=\"fusion-builder-row fusion-row\"><div class=\"fusion-layout-column fusion_builder_column fusion-builder-column-2 fusion_builder_column_1_1 1_1 fusion-one-full fusion-column-first fusion-column-last\" style=\"--awb-bg-size:cover;\"><div class=\"fusion-column-wrapper fusion-flex-column-wrapper-legacy\"><div class=\"accordian fusion-accordian\" style=\"--awb-border-size:1px;--awb-icon-size:23px;--awb-content-font-size:14.5px;--awb-icon-alignment:left;--awb-hover-color:#f9f9f9;--awb-border-color:#cccccc;--awb-background-color:#ffffff;--awb-divider-color:#e0dede;--awb-divider-hover-color:#e0dede;--awb-icon-color:#62d6c2;--awb-title-color:#189b7a;--awb-content-color:#000000;--awb-icon-box-color:#333333;--awb-toggle-hover-accent-color:rgba(0,155,116,0.63);--awb-title-font-family:Arial, Helvetica, sans-serif;--awb-title-font-weight:700;--awb-title-font-style:normal;--awb-title-font-size:16px;--awb-content-font-family:Arial, Helvetica, sans-serif;--awb-content-font-style:normal;--awb-content-font-weight:400;\"><div class=\"panel-group fusion-toggle-icon-boxed\" id=\"accordion-500-1\"><div class=\"fusion-panel panel-default panel-184c4bcccc9f312de fusion-toggle-has-divider\"><div class=\"panel-heading\"><h4 class=\"panel-title toggle\" id=\"toggle_184c4bcccc9f312de\"><a aria-expanded=\"false\" aria-controls=\"184c4bcccc9f312de\" role=\"button\" data-toggle=\"collapse\" data-parent=\"#accordion-500-1\" data-target=\"#184c4bcccc9f312de\" href=\"#184c4bcccc9f312de\"><span class=\"fusion-toggle-icon-wrapper\" aria-hidden=\"true\"><i class=\"fa-fusion-box active-icon awb-icon-minus\" aria-hidden=\"true\"><\/i><i class=\"fa-fusion-box inactive-icon awb-icon-plus\" aria-hidden=\"true\"><\/i><\/span><span class=\"fusion-toggle-heading\">A Little Story About Brent<\/span><\/a><\/h4><\/div><div id=\"184c4bcccc9f312de\" class=\"panel-collapse collapse \" aria-labelledby=\"toggle_184c4bcccc9f312de\"><div class=\"panel-body toggle-content fusion-clearfix\">\n<p>Dr. Brent Derry received his B.Sc. from Carleton University, his M.Sc. from McMaster University, and his PhD from the University of California, Santa Barbara. His PhD thesis research with Dr. Leslie Wilson focused on elucidating the molecular mechanism by which the anti-cancer drug taxol suppresses microtubule dynamics, and the role of beta-tubulin isotypes in taxol resistance. Derry carried out his postdoctoral training with Dr. Joel Rothman at the University of California where he identified and characterized the <em>C. elegans<\/em> p53 tumour suppressor gene.<\/p>\n<p>In 2003 Derry joined the Research Institute as a scientist. His laboratory is focused on the application of genetics, functional genomics, and biochemical techniques to understand signaling pathways deregulated in paediatric diseases, such as cancer and cerebral cavernous malformations.<\/p>\n<p>Brent may be part Senior Scientist, part Professor, part Editor, part Collaborator\u00a0but he also exemplifies to be\u00a05 parts mentor,\u00a04 parts geek, 3 parts family-man, 2 parts rock star and 1 part song writer. Can you have too many parts?<\/p>\n<\/div><\/div><\/div><\/div><\/div><div class=\"fusion-sep-clear\"><\/div><div class=\"fusion-separator fusion-full-width-sep\" style=\"margin-left: auto;margin-right: auto;margin-top:40px;width:100%;\"><\/div><div class=\"fusion-sep-clear\"><\/div><div class=\"fusion-soundcloud\"><iframe scrolling=\"no\" frameborder=\"no\" width=\"100%\" height=\"166\" allow=\"autoplay\" src=\"https:\/\/w.soundcloud.com\/player\/?url=https:\/\/soundcloud.com\/brent-derry\/swing-low-sweet-chariot&amp;auto_play=false&amp;hide_related=true&amp;show_comments=false&amp;show_user=false&amp;show_reposts=false&amp;visual=false&amp;color=000000\" title=\"soundcloud\"><\/iframe><\/div><div class=\"fusion-clearfix\"><\/div><\/div><\/div><\/div><\/div><\/p>\n","protected":false},"excerpt":{"rendered":"","protected":false},"author":2,"featured_media":0,"parent":0,"menu_order":0,"comment_status":"closed","ping_status":"closed","template":"","meta":{"_bbp_topic_count":0,"_bbp_reply_count":0,"_bbp_total_topic_count":0,"_bbp_total_reply_count":0,"_bbp_voice_count":0,"_bbp_anonymous_reply_count":0,"_bbp_topic_count_hidden":0,"_bbp_reply_count_hidden":0,"_bbp_forum_subforum_count":0,"footnotes":""},"class_list":["post-500","page","type-page","status-publish","hentry"],"yoast_head":"<!-- This site is optimized with the Yoast SEO Premium plugin v27.0 (Yoast SEO v27.0) - https:\/\/yoast.com\/product\/yoast-seo-premium-wordpress\/ -->\n<title>The Leader - Derry Lab<\/title>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/lab.research.sickkids.ca\/derry\/meet-the-scientist\/\" \/>\n<meta property=\"og:locale\" content=\"en_US\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"The Leader\" \/>\n<meta property=\"og:url\" content=\"https:\/\/lab.research.sickkids.ca\/derry\/meet-the-scientist\/\" \/>\n<meta property=\"og:site_name\" content=\"Derry Lab\" \/>\n<meta property=\"article:modified_time\" content=\"2026-04-13T14:39:01+00:00\" \/>\n<meta name=\"twitter:card\" content=\"summary_large_image\" \/>\n<meta name=\"twitter:label1\" content=\"Est. reading time\" \/>\n\t<meta name=\"twitter:data1\" content=\"2 minutes\" \/>\n<script type=\"application\/ld+json\" class=\"yoast-schema-graph\">{\"@context\":\"https:\/\/schema.org\",\"@graph\":[{\"@type\":\"WebPage\",\"@id\":\"https:\/\/lab.research.sickkids.ca\/derry\/meet-the-scientist\/\",\"url\":\"https:\/\/lab.research.sickkids.ca\/derry\/meet-the-scientist\/\",\"name\":\"The Leader - Derry Lab\",\"isPartOf\":{\"@id\":\"https:\/\/lab.research.sickkids.ca\/derry\/#website\"},\"datePublished\":\"2015-01-12T18:50:57+00:00\",\"dateModified\":\"2026-04-13T14:39:01+00:00\",\"breadcrumb\":{\"@id\":\"https:\/\/lab.research.sickkids.ca\/derry\/meet-the-scientist\/#breadcrumb\"},\"inLanguage\":\"en-US\",\"potentialAction\":[{\"@type\":\"ReadAction\",\"target\":[\"https:\/\/lab.research.sickkids.ca\/derry\/meet-the-scientist\/\"]}]},{\"@type\":\"BreadcrumbList\",\"@id\":\"https:\/\/lab.research.sickkids.ca\/derry\/meet-the-scientist\/#breadcrumb\",\"itemListElement\":[{\"@type\":\"ListItem\",\"position\":1,\"name\":\"Home\",\"item\":\"https:\/\/lab.research.sickkids.ca\/derry\/\"},{\"@type\":\"ListItem\",\"position\":2,\"name\":\"The Leader\"}]},{\"@type\":\"WebSite\",\"@id\":\"https:\/\/lab.research.sickkids.ca\/derry\/#website\",\"url\":\"https:\/\/lab.research.sickkids.ca\/derry\/\",\"name\":\"Derry Lab\",\"description\":\"Disease &amp; 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